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Unknown case study#2 Your patient is a 26 yo male who presented to the hospital with complaints
of a recent onset of headaches and swelling in his face, with increasing dyspnea and chest
discomfort during the past two weeks. The patient does not report fever or night sweats. The
patient's vitals are as follows: Temp=36.7C,BP=145/65mmHg. Heart sounds were mildly muted,
with no murmur. Decreased lung sounds detected in the right lower lung field. On exam, you (the
Attending physician) find a young patient in stable condition, but visibly distressed. Unilateral
anterior cervical lymphadenopathy on the patient's right side is palpated, a non-tender, rubbery,
fixed lymph node of approximately 2cm2 in size. You order a complete blood count (CBC) and
Liver function tests (LFTs), a chest X-ray and a mediastinal CT scan, as well as tissue biopsy and
immunophenotyping. 2.A. Based on initial history provide a complete list of all differential
diagnoses you would consider before results are back The blood smear looks like this: 2.B. The
malignant cells seem to have a mixed morphology, describe them here as specifically as possible
The tissue biopsies look like this: H&E-100x total magnification TdT (brown stain)
Myeloperoxidase (brown stain)

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Unknown case study2 Your patient is a 26 yo male who presen.pdf

  • 1. Unknown case study#2 Your patient is a 26 yo male who presented to the hospital with complaints of a recent onset of headaches and swelling in his face, with increasing dyspnea and chest discomfort during the past two weeks. The patient does not report fever or night sweats. The patient's vitals are as follows: Temp=36.7C,BP=145/65mmHg. Heart sounds were mildly muted, with no murmur. Decreased lung sounds detected in the right lower lung field. On exam, you (the Attending physician) find a young patient in stable condition, but visibly distressed. Unilateral anterior cervical lymphadenopathy on the patient's right side is palpated, a non-tender, rubbery, fixed lymph node of approximately 2cm2 in size. You order a complete blood count (CBC) and Liver function tests (LFTs), a chest X-ray and a mediastinal CT scan, as well as tissue biopsy and immunophenotyping. 2.A. Based on initial history provide a complete list of all differential diagnoses you would consider before results are back The blood smear looks like this: 2.B. The malignant cells seem to have a mixed morphology, describe them here as specifically as possible The tissue biopsies look like this: H&E-100x total magnification TdT (brown stain) Myeloperoxidase (brown stain)