This study assessed the treatment outcomes of 101 Pakistani children with unilateral cleft lip and palate using the EuroCran index. The study found that 42% of cases had a favorable dental outcome while 58% had an unfavorable outcome. Modified Millard cheiloplasty and VY pushback palatoplasty techniques were associated with higher odds of unfavorable outcomes compared to conventional techniques. The study provides valuable data on cleft treatment outcomes in the Pakistani population.
This study examined the prevalence of impacted maxillary canines in the Arab population in Israel. The researchers reviewed records of 4250 patients and found 82 cases of impacted canines, a prevalence of 3.7%. Females had a higher prevalence than males, at 1.1% versus 0.8%. Most cases were unilateral, with the left side being more commonly impacted. The results suggest racial and genetic factors may influence canine impaction rates, as this population had a higher prevalence than previous studies in other areas. Early diagnosis and treatment of impacted canines can help guide them into proper alignment and avoid more complex treatment needs.
1. The document outlines Dr. Mohammed Almuzian's process for orthodontic diagnosis, which involves gathering information from the patient's medical history, dental history, clinical examination, and diagnostic records.
2. The clinical examination includes assessing the patient's facial profile, smile, dental alignment, occlusion, and temporomandibular joint from frontal, lateral, and intraoral views.
3. Diagnostic records like dental casts, radiographs, and photographs are evaluated to aid in diagnosis, treatment planning, monitoring treatment, and for legal and teaching purposes. Storage of records for at least 11 years is recommended.
An orthodontic index is used to objectively assess malocclusions. The document discusses several commonly used indices, including Angle's Classification, the Index of Orthodontic Treatment Need (IOTN), and the Peer Assessment Rating (PAR) index. The IOTN consists of an Aesthetic Component and a Dental Health Component to determine treatment need and priority. The PAR index assesses treatment difficulty and outcomes. Overall, orthodontic indices are tools to classify, diagnose, and evaluate the need, complexity, and results of orthodontic treatment in a reliable and standardized manner.
Clinical study of impacted maxillary canine in the Arab population in IsraelAbu-Hussein Muhamad
The objective of the present study was to determine the prevalence of impacted maxillary canine in patients in Arabs
Community in Israel (ARAB48,Israel) visiting our Center For Dentistry,Research & Aesthetics,Jatt,Almothalath,Israel,
4250 patients . This study comprises data from patients who attended the O.P.D.2200 patients between Jun. 2006 to Dec
2013. Patients were examined in order to detect the impacted maxillary canines by intraoral examination, palpation, dental
records and followed by radiographs. It was found that the prevalence of canine impaction was 0,8 % (N=4250), 1,6
(N=2200), 43,9 (N-82) in males and 1,1% (N=4250), 2,1 (N=2200), 56,1 (N-82) in females suggesting that prevalence of
impacted maxillary canines is more in females than males and it is statistically significant. The overall prevalence for
maxillary impacted canines was found to be 3,7 % (N=2200) which suggested that it is much higher than previous studies.
The results of this study were slightly different than other studies, while the dissimilarities may be attributed to the sample
selection, method of the study and area of patient selection, which suggest racial and genetic differences.
This document discusses various orthodontic indices used to classify and assess malocclusions, treatment needs, and treatment outcomes. It provides descriptions of commonly used indices such as the Index of Orthodontic Treatment Need (IOTN), Peer Assessment Rating (PAR), and Goslon Yardstick. The document emphasizes that an ideal orthodontic index should be simple, reliable, objective, and able to differentiate between handicapping and non-handicapping malocclusions. It also outlines the specific components and scoring methods of several popular indices.
This study aimed to determine the prevalence of impacted maxillary canines in the Palestinian population visiting a dental center in Israel between 2006-2013. The researchers examined 4250 patient records and found an overall prevalence of impacted canines to be 3.7%, higher than previous studies. Specifically, the prevalence was 0.8% in males and 1.1% in females, suggesting a higher rate in females. Most impacted canines were palatally positioned. The results differed slightly from other studies, possibly due to differences in sample selection, study methods, and patient populations examined. Accurate assessment of an impacted canine's position is important to determine the appropriate treatment approach.
This study examined the prevalence of impacted maxillary canines in the Arab population in Israel. The researchers reviewed records of 4250 patients and found 82 cases of impacted canines, a prevalence of 3.7%. Females had a higher prevalence than males, at 1.1% versus 0.8%. Most cases were unilateral, with the left side being more commonly impacted. The results suggest racial and genetic factors may influence canine impaction rates, as this population had a higher prevalence than previous studies in other areas. Early diagnosis and treatment of impacted canines can help guide them into proper alignment and avoid more complex treatment needs.
1. The document outlines Dr. Mohammed Almuzian's process for orthodontic diagnosis, which involves gathering information from the patient's medical history, dental history, clinical examination, and diagnostic records.
2. The clinical examination includes assessing the patient's facial profile, smile, dental alignment, occlusion, and temporomandibular joint from frontal, lateral, and intraoral views.
3. Diagnostic records like dental casts, radiographs, and photographs are evaluated to aid in diagnosis, treatment planning, monitoring treatment, and for legal and teaching purposes. Storage of records for at least 11 years is recommended.
An orthodontic index is used to objectively assess malocclusions. The document discusses several commonly used indices, including Angle's Classification, the Index of Orthodontic Treatment Need (IOTN), and the Peer Assessment Rating (PAR) index. The IOTN consists of an Aesthetic Component and a Dental Health Component to determine treatment need and priority. The PAR index assesses treatment difficulty and outcomes. Overall, orthodontic indices are tools to classify, diagnose, and evaluate the need, complexity, and results of orthodontic treatment in a reliable and standardized manner.
Clinical study of impacted maxillary canine in the Arab population in IsraelAbu-Hussein Muhamad
The objective of the present study was to determine the prevalence of impacted maxillary canine in patients in Arabs
Community in Israel (ARAB48,Israel) visiting our Center For Dentistry,Research & Aesthetics,Jatt,Almothalath,Israel,
4250 patients . This study comprises data from patients who attended the O.P.D.2200 patients between Jun. 2006 to Dec
2013. Patients were examined in order to detect the impacted maxillary canines by intraoral examination, palpation, dental
records and followed by radiographs. It was found that the prevalence of canine impaction was 0,8 % (N=4250), 1,6
(N=2200), 43,9 (N-82) in males and 1,1% (N=4250), 2,1 (N=2200), 56,1 (N-82) in females suggesting that prevalence of
impacted maxillary canines is more in females than males and it is statistically significant. The overall prevalence for
maxillary impacted canines was found to be 3,7 % (N=2200) which suggested that it is much higher than previous studies.
The results of this study were slightly different than other studies, while the dissimilarities may be attributed to the sample
selection, method of the study and area of patient selection, which suggest racial and genetic differences.
This document discusses various orthodontic indices used to classify and assess malocclusions, treatment needs, and treatment outcomes. It provides descriptions of commonly used indices such as the Index of Orthodontic Treatment Need (IOTN), Peer Assessment Rating (PAR), and Goslon Yardstick. The document emphasizes that an ideal orthodontic index should be simple, reliable, objective, and able to differentiate between handicapping and non-handicapping malocclusions. It also outlines the specific components and scoring methods of several popular indices.
This study aimed to determine the prevalence of impacted maxillary canines in the Palestinian population visiting a dental center in Israel between 2006-2013. The researchers examined 4250 patient records and found an overall prevalence of impacted canines to be 3.7%, higher than previous studies. Specifically, the prevalence was 0.8% in males and 1.1% in females, suggesting a higher rate in females. Most impacted canines were palatally positioned. The results differed slightly from other studies, possibly due to differences in sample selection, study methods, and patient populations examined. Accurate assessment of an impacted canine's position is important to determine the appropriate treatment approach.
This document provides an overview of case history, diagnosis, and treatment planning procedures. It discusses collecting information such as the chief complaint, medical history, history of present illness, and examinations including general, extraoral, intraoral, and diagnostic assessments. Indices for gingivitis and plaque are described. Various diagnostic aids for dental caries are listed. Phases of treatment planning including systemic, preparatory, corrective, preventive, and maintenance are outlined.
Assessment of correlation of periodontitis in teeth adjacent to implant and p...Dr. Anuj S Parihar
Aims: The present study was conducted to determine correlation between peri‑implantitis and periodontitis in adjacent teeth. Materials and Methods: The present study was conducted on 58 patients with 84 dental implants. They were divided into two groups, group I (50) was with peri‑implantitis and group II (34) was without it. In all patients, probing depth (PD), gingival recession (GR), and clinical attachment loss (CAL) was calculated around implant, adjacent to implant and on contralateral side. Obtained data were statistically analyzed using statistical software IBM SPSS Statistics for Windows, Version 21.0. Armonk, NY: IBM Corp with one‑way analysis of variance. Results: Males were 30 with 52 dental implants and females were 28 with 32 dental implants. CAL was 5.82 ± 0.52 in group I and 3.62 ± 0.63 in group II (P = 0.001) around implants. PD was 4.28 ± 1.26 in group I and 2.20 ± 0.52
in group II around adjacent teeth (P = 0.002). PD around contralateral teeth was significant (P = 0.05) in group I (3.18 ± 1.01) and group II (2.71 ± 0.73). Conclusion: Periodontitis has negative effect on implant success. Teeth adjacent to dental implant plays an important role in deciding the success or failure of implant. Maintenance of periodontal health is of paramount importance for successful implant therapy.
This document discusses periodontal indices and their reliability and usefulness in measuring periodontal disease. It defines key terms like plaque, calculus, and debris. It describes the ideal requisites of an index, including clarity, simplicity, objectivity, validity, reliability, and sensitivity. Several commonly used oral hygiene and plaque indices are explained, including the Oral Hygiene Index, Simplified Oral Hygiene Index, Patient Hygiene Performance Index, and Plaque Index. The document provides details on scoring criteria and how to calculate scores for each index.
This document summarizes a meta-analysis on the incidence of root resorption after replantation of avulsed teeth. It finds that the incidence of root resorption is high, with replacement root resorption being the most common at 51%, followed by inflammatory root resorption at 23.2% and surface root resorption at 13.3%. Internal root resorption is relatively rare at 1.2%. The studies showed maxillary incisors were most affected and that the risk of different types of root resorption depended on factors like the stage of root development and treatment of the tooth. Limitations included heterogeneity between studies and lack of standardization.
This chapter discusses the classification and etiology of malocclusion. Malocclusion can result from genetic factors, environmental factors, or a combination. Environmental influences include habits like digit-sucking and premature tooth loss from caries or trauma. Several commonly used classification systems are described, including Angle's classification (Classes I, II, III based on molar relationship), the British Standards Institute classification (based on incisor relationship), and the Index of Orthodontic Treatment Need (IOTN) which evaluates dental health and psychosocial impacts. The goal of orthodontic treatment is a functional occlusion without interference or pathology, though lack of an ideal occlusion may not cause long-term issues.
Health state utilities of periodontitis patients UKM
This study assessed the effectiveness of periodontal treatment provided at government clinics in Malaysia using patient-reported outcomes. 165 patients newly diagnosed with periodontitis were recruited. Patients completed oral health questionnaires before and after treatment to assess quality of life impacts. Clinical parameters were also measured. Results showed significant improvements in oral health-related quality of life, health state utilities, and clinical parameters after treatment. The use of health state utilities demonstrated treatment effectiveness and should be considered in economic evaluations of dental treatments. Overall, the study found that periodontal treatment significantly improved patients' oral health-related quality of life and clinical outcomes.
Clinical study of impacted maxillary canine in the Arab population in IsraelAbu-Hussein Muhamad
The objective of the present study was to determine the prevalence of impacted maxillary canine in patients in Arabs Community in Israel (ARAB48,Israel) visiting our Center For Dentistry,Research & Aesthetics,Jatt,Almothalath,Israel, 4250 patients . This study comprises data from patients who attended the O.P.D.2200 patients between Jun. 2006 to Dec 2013. Patients were examined in order to detect the impacted maxillary canines by intraoral examination, palpation, dental records and followed by radiographs. It was found that the prevalence of canine impaction was 0,8 % (N=4250), 1,6 (N=2200), 43,9 (N-82) in males and 1,1% (N=4250), 2,1 (N=2200), 56,1 (N-82) in females suggesting that prevalence of impacted maxillary canines is more in females than males and it is statistically significant. The overall prevalence for maxillary impacted canines was found to be 3,7 % (N=2200) which suggested that it is much higher than previous studies. The results of this study were slightly different than other studies, while the dissimilarities may be attributed to the sample selection, method of the study and area of patient selection, which suggest racial and genetic differences.
orthodontic epidemiological indices
Occlusal Feature Index (Poulton & Aaronson, 1961)
Index of Tooth Position (Massler & Frankel, 1951)
Malalignment Index (Van Kirk & Pennel, 1959)
The Bjork Method (1964)
Summers’ Occlusal Index (1971)
The FDI method (Baume et al, 1973)
Little’s Irregularity Index (1975)
Handicapping Labio-lingual Deviation index (HLD) (Draker, 1960, 1967)
Swedish Medical Board Index (SMHB 1966; Linder Aronson, 1974, 1976)
Dental Aesthetic Index (DAI) (Cons et al, 1986)
Index of Orthodontic treatment Need (IOTN) (Brook & Shaw, 1989)
Index of Complexity, Outcome & Need (ICON) (Daniel & Richmond, 2000)
Peer Assessment Rating Index (PAR) (Richmond et al, 1992)
Int Endodontic J - 2022 - Kvist - Clinical decision making of post‐treatment ...DrDipaliShah
This document discusses clinical decision making regarding post-treatment disease in root-filled teeth. It begins by noting that 25-50% of root-filled teeth show signs of post-treatment disease on radiographs, though many are asymptomatic. There is no consensus among clinicians on how to manage such cases. The document outlines the typical options of no treatment, monitoring, extraction, or retreatment via surgical or non-surgical methods. It discusses how decisions are inherently subjective based on a clinician's knowledge and experience. Descriptive research has found wide variation in how clinicians decide to manage individual cases. The concept of "success" and "failure" integrates biological, evaluative, and normative components, but health and disease exist
Oral Cancer Screening AAOM sincev 2018.pdfGanesh189547
This document discusses screening for oral cancer. It defines screening and organized versus opportunistic screening. While oral potentially malignant disorders affect 1-5% of the global population, the malignant transformation rate is low at <2% per year. Natural history studies show oral cavity cancer is often preceded by precursor lesions, though for HPV+ oropharyngeal cancer this is rare. Key questions around oral cancer screening address whether it is an important health problem, appropriate screening tests and their performance, impact on morbidity/mortality, and cost-effectiveness. Studies in India and Taiwan found screening reduced oral cancer mortality in high-risk groups. Simulation studies suggest opportunistic screening of high-risk patients may be cost-effective. The USP
This study compared the effects of the modified Furlow palatoplasty technique versus the two-flap palatoplasty technique on ear function and hearing outcomes in 72 cleft palate patients over one year. The results found that at three months post-operation, the modified Furlow group had significantly lower middle ear effusion and acute otitis media rates compared to the two-flap group. However, the differences between groups were not statistically significant at other follow-up periods of one month, six months, and one year.
This document presents a case report of a central odontogenic fibroma. It describes a patient who presented with asymptomatic expansion of the buccal and lingual cortical plates. Radiographs and biopsy revealed a well-defined mixed radiodensity lesion containing epithelial islands and calcified material resembling dentin or cementum, consistent with central odontogenic fibroma. The lesion was surgically removed. Histological examination confirmed the diagnosis of central odontogenic fibroma, a rare benign odontogenic tumor originating from dental ectomesenchyme.
This document discusses apical periodontitis, including its definition, causes, prognosis, and epidemiology. Some key points:
- Apical periodontitis is an inflammatory response to infection of the root canal system, which can include both acute and chronic phases.
- The prognosis of endodontic treatment depends on preventing apical periodontitis by eliminating root canal infection.
- Epidemiological studies show the prevalence of apical periodontitis varies widely between populations, from 20-80% depending on factors like access to dental care.
- Reasons for tooth extraction often include apical periodontitis and failed endodontic treatment, though historically it has not been well recognized as a disease. Progn
This randomized controlled clinical trial compared the efficacy of MI varnish and Clinpro XT varnish in reducing dentinal hypersensitivity. The study found that MI varnish, a calcium phosphate-based varnish, was more effective at reducing sensitivity based on ice test and cold water test scores compared to Clinpro XT varnish, a resin modified glass ionomer-based varnish. Both varnishes showed a reduction in sensitivity but MI varnish produced approximately double the percentage change in sensitivity scores compared to Clinpro XT varnish. The study concluded that MI varnish was more effective at reducing dentinal hypersensitivity.
The document discusses the prognosis of endodontic therapy and retaining teeth. It defines prognosis as the anticipated outcome or recovery from a disease based on its usual course. The goal of endodontic treatment is to prevent and treat apical periodontitis by eliminating root canal infections. Left untreated, apical periodontitis can persist and progress from acute to chronic phases. Studies show a high prevalence of apical periodontitis, with rates varying significantly between countries. Factors like diabetes, lack of coronal coverage, and previous trauma can negatively impact prognosis. With effective treatment, the vast majority of teeth can be retained.
Malocclusion And Deleterious Oral Habits In South Indian Adolscent Population...DrHeena tiwari
This study evaluated the prevalence of malocclusion and associated oral habits in South Indian adolescents. The researchers assessed 1000 12-15 year olds using the Dental Aesthetic Index and found that 52% had some form of malocclusion. Deleterious oral habits were present in 21.2% of subjects and those with habits were more likely to have malocclusion than those without. Specific habits like tongue thrusting and mouth breathing were correlated with traits like crowding and open bite. The study concludes that malocclusion in this population is directly linked to the presence of oral habits.
This study examined the prevalence of tooth agenesis (hypodontia) in orthodontic patients from the Arab population in Israel. The researchers reviewed panoramic radiographs of 500 patients aged 12-39 years old. They found that 57 patients (2.6% prevalence) had hypodontia, missing a total of 167 permanent teeth. The most commonly missing tooth was the mandibular second premolar. This prevalence of hypodontia in the Arab population of Israel falls within the typical global range of 1.6-9.6%, and indicates hypodontia is present but not unusually high compared to other populations.
- Almost half of the participants were completely satisfied with their dental appearance and tooth colour.
- Satisfaction differed between age groups and dental status - half of younger/middle-aged patients with natural teeth were completely satisfied, while half of older patients were moderately satisfied.
- Those with composite restorations were mostly moderately satisfied with appearance, while over 70% of older patients were dissatisfied with their tooth colour.
This document provides an overview of case history, diagnosis, and treatment planning procedures. It discusses collecting information such as the chief complaint, medical history, history of present illness, and examinations including general, extraoral, intraoral, and diagnostic assessments. Indices for gingivitis and plaque are described. Various diagnostic aids for dental caries are listed. Phases of treatment planning including systemic, preparatory, corrective, preventive, and maintenance are outlined.
Assessment of correlation of periodontitis in teeth adjacent to implant and p...Dr. Anuj S Parihar
Aims: The present study was conducted to determine correlation between peri‑implantitis and periodontitis in adjacent teeth. Materials and Methods: The present study was conducted on 58 patients with 84 dental implants. They were divided into two groups, group I (50) was with peri‑implantitis and group II (34) was without it. In all patients, probing depth (PD), gingival recession (GR), and clinical attachment loss (CAL) was calculated around implant, adjacent to implant and on contralateral side. Obtained data were statistically analyzed using statistical software IBM SPSS Statistics for Windows, Version 21.0. Armonk, NY: IBM Corp with one‑way analysis of variance. Results: Males were 30 with 52 dental implants and females were 28 with 32 dental implants. CAL was 5.82 ± 0.52 in group I and 3.62 ± 0.63 in group II (P = 0.001) around implants. PD was 4.28 ± 1.26 in group I and 2.20 ± 0.52
in group II around adjacent teeth (P = 0.002). PD around contralateral teeth was significant (P = 0.05) in group I (3.18 ± 1.01) and group II (2.71 ± 0.73). Conclusion: Periodontitis has negative effect on implant success. Teeth adjacent to dental implant plays an important role in deciding the success or failure of implant. Maintenance of periodontal health is of paramount importance for successful implant therapy.
This document discusses periodontal indices and their reliability and usefulness in measuring periodontal disease. It defines key terms like plaque, calculus, and debris. It describes the ideal requisites of an index, including clarity, simplicity, objectivity, validity, reliability, and sensitivity. Several commonly used oral hygiene and plaque indices are explained, including the Oral Hygiene Index, Simplified Oral Hygiene Index, Patient Hygiene Performance Index, and Plaque Index. The document provides details on scoring criteria and how to calculate scores for each index.
This document summarizes a meta-analysis on the incidence of root resorption after replantation of avulsed teeth. It finds that the incidence of root resorption is high, with replacement root resorption being the most common at 51%, followed by inflammatory root resorption at 23.2% and surface root resorption at 13.3%. Internal root resorption is relatively rare at 1.2%. The studies showed maxillary incisors were most affected and that the risk of different types of root resorption depended on factors like the stage of root development and treatment of the tooth. Limitations included heterogeneity between studies and lack of standardization.
This chapter discusses the classification and etiology of malocclusion. Malocclusion can result from genetic factors, environmental factors, or a combination. Environmental influences include habits like digit-sucking and premature tooth loss from caries or trauma. Several commonly used classification systems are described, including Angle's classification (Classes I, II, III based on molar relationship), the British Standards Institute classification (based on incisor relationship), and the Index of Orthodontic Treatment Need (IOTN) which evaluates dental health and psychosocial impacts. The goal of orthodontic treatment is a functional occlusion without interference or pathology, though lack of an ideal occlusion may not cause long-term issues.
Health state utilities of periodontitis patients UKM
This study assessed the effectiveness of periodontal treatment provided at government clinics in Malaysia using patient-reported outcomes. 165 patients newly diagnosed with periodontitis were recruited. Patients completed oral health questionnaires before and after treatment to assess quality of life impacts. Clinical parameters were also measured. Results showed significant improvements in oral health-related quality of life, health state utilities, and clinical parameters after treatment. The use of health state utilities demonstrated treatment effectiveness and should be considered in economic evaluations of dental treatments. Overall, the study found that periodontal treatment significantly improved patients' oral health-related quality of life and clinical outcomes.
Clinical study of impacted maxillary canine in the Arab population in IsraelAbu-Hussein Muhamad
The objective of the present study was to determine the prevalence of impacted maxillary canine in patients in Arabs Community in Israel (ARAB48,Israel) visiting our Center For Dentistry,Research & Aesthetics,Jatt,Almothalath,Israel, 4250 patients . This study comprises data from patients who attended the O.P.D.2200 patients between Jun. 2006 to Dec 2013. Patients were examined in order to detect the impacted maxillary canines by intraoral examination, palpation, dental records and followed by radiographs. It was found that the prevalence of canine impaction was 0,8 % (N=4250), 1,6 (N=2200), 43,9 (N-82) in males and 1,1% (N=4250), 2,1 (N=2200), 56,1 (N-82) in females suggesting that prevalence of impacted maxillary canines is more in females than males and it is statistically significant. The overall prevalence for maxillary impacted canines was found to be 3,7 % (N=2200) which suggested that it is much higher than previous studies. The results of this study were slightly different than other studies, while the dissimilarities may be attributed to the sample selection, method of the study and area of patient selection, which suggest racial and genetic differences.
orthodontic epidemiological indices
Occlusal Feature Index (Poulton & Aaronson, 1961)
Index of Tooth Position (Massler & Frankel, 1951)
Malalignment Index (Van Kirk & Pennel, 1959)
The Bjork Method (1964)
Summers’ Occlusal Index (1971)
The FDI method (Baume et al, 1973)
Little’s Irregularity Index (1975)
Handicapping Labio-lingual Deviation index (HLD) (Draker, 1960, 1967)
Swedish Medical Board Index (SMHB 1966; Linder Aronson, 1974, 1976)
Dental Aesthetic Index (DAI) (Cons et al, 1986)
Index of Orthodontic treatment Need (IOTN) (Brook & Shaw, 1989)
Index of Complexity, Outcome & Need (ICON) (Daniel & Richmond, 2000)
Peer Assessment Rating Index (PAR) (Richmond et al, 1992)
Int Endodontic J - 2022 - Kvist - Clinical decision making of post‐treatment ...DrDipaliShah
This document discusses clinical decision making regarding post-treatment disease in root-filled teeth. It begins by noting that 25-50% of root-filled teeth show signs of post-treatment disease on radiographs, though many are asymptomatic. There is no consensus among clinicians on how to manage such cases. The document outlines the typical options of no treatment, monitoring, extraction, or retreatment via surgical or non-surgical methods. It discusses how decisions are inherently subjective based on a clinician's knowledge and experience. Descriptive research has found wide variation in how clinicians decide to manage individual cases. The concept of "success" and "failure" integrates biological, evaluative, and normative components, but health and disease exist
Oral Cancer Screening AAOM sincev 2018.pdfGanesh189547
This document discusses screening for oral cancer. It defines screening and organized versus opportunistic screening. While oral potentially malignant disorders affect 1-5% of the global population, the malignant transformation rate is low at <2% per year. Natural history studies show oral cavity cancer is often preceded by precursor lesions, though for HPV+ oropharyngeal cancer this is rare. Key questions around oral cancer screening address whether it is an important health problem, appropriate screening tests and their performance, impact on morbidity/mortality, and cost-effectiveness. Studies in India and Taiwan found screening reduced oral cancer mortality in high-risk groups. Simulation studies suggest opportunistic screening of high-risk patients may be cost-effective. The USP
This study compared the effects of the modified Furlow palatoplasty technique versus the two-flap palatoplasty technique on ear function and hearing outcomes in 72 cleft palate patients over one year. The results found that at three months post-operation, the modified Furlow group had significantly lower middle ear effusion and acute otitis media rates compared to the two-flap group. However, the differences between groups were not statistically significant at other follow-up periods of one month, six months, and one year.
This document presents a case report of a central odontogenic fibroma. It describes a patient who presented with asymptomatic expansion of the buccal and lingual cortical plates. Radiographs and biopsy revealed a well-defined mixed radiodensity lesion containing epithelial islands and calcified material resembling dentin or cementum, consistent with central odontogenic fibroma. The lesion was surgically removed. Histological examination confirmed the diagnosis of central odontogenic fibroma, a rare benign odontogenic tumor originating from dental ectomesenchyme.
This document discusses apical periodontitis, including its definition, causes, prognosis, and epidemiology. Some key points:
- Apical periodontitis is an inflammatory response to infection of the root canal system, which can include both acute and chronic phases.
- The prognosis of endodontic treatment depends on preventing apical periodontitis by eliminating root canal infection.
- Epidemiological studies show the prevalence of apical periodontitis varies widely between populations, from 20-80% depending on factors like access to dental care.
- Reasons for tooth extraction often include apical periodontitis and failed endodontic treatment, though historically it has not been well recognized as a disease. Progn
This randomized controlled clinical trial compared the efficacy of MI varnish and Clinpro XT varnish in reducing dentinal hypersensitivity. The study found that MI varnish, a calcium phosphate-based varnish, was more effective at reducing sensitivity based on ice test and cold water test scores compared to Clinpro XT varnish, a resin modified glass ionomer-based varnish. Both varnishes showed a reduction in sensitivity but MI varnish produced approximately double the percentage change in sensitivity scores compared to Clinpro XT varnish. The study concluded that MI varnish was more effective at reducing dentinal hypersensitivity.
The document discusses the prognosis of endodontic therapy and retaining teeth. It defines prognosis as the anticipated outcome or recovery from a disease based on its usual course. The goal of endodontic treatment is to prevent and treat apical periodontitis by eliminating root canal infections. Left untreated, apical periodontitis can persist and progress from acute to chronic phases. Studies show a high prevalence of apical periodontitis, with rates varying significantly between countries. Factors like diabetes, lack of coronal coverage, and previous trauma can negatively impact prognosis. With effective treatment, the vast majority of teeth can be retained.
Malocclusion And Deleterious Oral Habits In South Indian Adolscent Population...DrHeena tiwari
This study evaluated the prevalence of malocclusion and associated oral habits in South Indian adolescents. The researchers assessed 1000 12-15 year olds using the Dental Aesthetic Index and found that 52% had some form of malocclusion. Deleterious oral habits were present in 21.2% of subjects and those with habits were more likely to have malocclusion than those without. Specific habits like tongue thrusting and mouth breathing were correlated with traits like crowding and open bite. The study concludes that malocclusion in this population is directly linked to the presence of oral habits.
This study examined the prevalence of tooth agenesis (hypodontia) in orthodontic patients from the Arab population in Israel. The researchers reviewed panoramic radiographs of 500 patients aged 12-39 years old. They found that 57 patients (2.6% prevalence) had hypodontia, missing a total of 167 permanent teeth. The most commonly missing tooth was the mandibular second premolar. This prevalence of hypodontia in the Arab population of Israel falls within the typical global range of 1.6-9.6%, and indicates hypodontia is present but not unusually high compared to other populations.
- Almost half of the participants were completely satisfied with their dental appearance and tooth colour.
- Satisfaction differed between age groups and dental status - half of younger/middle-aged patients with natural teeth were completely satisfied, while half of older patients were moderately satisfied.
- Those with composite restorations were mostly moderately satisfied with appearance, while over 70% of older patients were dissatisfied with their tooth colour.
Local Advanced Lung Cancer: Artificial Intelligence, Synergetics, Complex Sys...Oleg Kshivets
Overall life span (LS) was 1671.7±1721.6 days and cumulative 5YS reached 62.4%, 10 years – 50.4%, 20 years – 44.6%. 94 LCP lived more than 5 years without cancer (LS=2958.6±1723.6 days), 22 – more than 10 years (LS=5571±1841.8 days). 67 LCP died because of LC (LS=471.9±344 days). AT significantly improved 5YS (68% vs. 53.7%) (P=0.028 by log-rank test). Cox modeling displayed that 5YS of LCP significantly depended on: N0-N12, T3-4, blood cell circuit, cell ratio factors (ratio between cancer cells-CC and blood cells subpopulations), LC cell dynamics, recalcification time, heparin tolerance, prothrombin index, protein, AT, procedure type (P=0.000-0.031). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and N0-12 (rank=1), thrombocytes/CC (rank=2), segmented neutrophils/CC (3), eosinophils/CC (4), erythrocytes/CC (5), healthy cells/CC (6), lymphocytes/CC (7), stick neutrophils/CC (8), leucocytes/CC (9), monocytes/CC (10). Correct prediction of 5YS was 100% by neural networks computing (error=0.000; area under ROC curve=1.0).
Does Over-Masturbation Contribute to Chronic Prostatitis.pptxwalterHu5
In some case, your chronic prostatitis may be related to over-masturbation. Generally, natural medicine Diuretic and Anti-inflammatory Pill can help mee get a cure.
Adhd Medication Shortage Uk - trinexpharmacy.comreignlana06
The UK is currently facing a Adhd Medication Shortage Uk, which has left many patients and their families grappling with uncertainty and frustration. ADHD, or Attention Deficit Hyperactivity Disorder, is a chronic condition that requires consistent medication to manage effectively. This shortage has highlighted the critical role these medications play in the daily lives of those affected by ADHD. Contact : +1 (747) 209 – 3649 E-mail : sales@trinexpharmacy.com
Osteoporosis - Definition , Evaluation and Management .pdfJim Jacob Roy
Osteoporosis is an increasing cause of morbidity among the elderly.
In this document , a brief outline of osteoporosis is given , including the risk factors of osteoporosis fractures , the indications for testing bone mineral density and the management of osteoporosis
ABDOMINAL TRAUMA in pediatrics part one.drhasanrajab
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Unilateral Cleft Lip and Palate Treatment Outcome Assessment
1. Anas Imran Arshad, Mohammad Khrusheed Alam,
Mohd. Fadhli Khamis
ASSESSMENT OF POST-TREATMENT OUTCOME
OF PAKISTANI CHILDREN HAVING TOTAL
UNILATERAL CLEFT LIP AND PALATE USING
EUROCRAN INDEX
2. INTRODUCTION
• Cleft lip and palate (CLP) is defined as “non-fusion of the upper
lip and/or the roof of the mouth (hard and/or soft palate) which
appears as a gap in the affected structures” (Erverdi and Motro,
2015).
4. EPIDEMIOLOGY
• Unilateral Cleft Lip and Palate (UCLP) is one of the most
common congenital orofacial defects. (Murray, 1995)
• With an incidence of 1.91 per 1000 live births (Elahi et al.,
2004), cleft lip and palate is the second most
common birth defect behind cardiac defects. (Quereshy et al.,
2012)
6. WORKFLOW OF MANAGEMENT
Pre-natal Period
Paedodontist and
Orthodontist for dental
anomalies
Maxillofacial Surgeons
and plastic surgeons for
surgical consult
Prosthodontist for early
provision of obturators
Genetics expert for parent
counselling and pregnancy
planning
Neo-natal period 2 weeks- 6 months
NAM appliance for pre-surgical infant orthopaedics Primary surgical repair of lip and palate
Deciduous dentition 2- 7 years
Psychological consult, speech therapies and velopharyngeal repair Considerations for revision surgeries
Mixed dentition 7- 12 years
Combined efforts of orthodontist
and maxillofacial surgeon
Plan pre-surgical maxillary expansion
and secondary alveolar bone grafting
Planning of orthopaedic appliance
for maxillary growth modification
Permanent dentition 12 years to adult
Psychological motivation, speech therapies Considerations for orthognathic surgeries and nasolabial revisions
9. OUTCOME INDICES
Outcome indices assess the quality of CLP treatment provided.
There are various methods to assess the cleft outcomes, one of
the most popular method is dental arch relationships
assessment.
There are many indices which assess dental arch relationships
like, GOSLON, modified Huddart/Bodenham, and EUROCRAN.
10. Sk. Class I or II
Both centrals positive
Overjet and Overbite
Grade 1(a)
(b) No Overjet and
Overbite
EUROCRAN index ( Based on Dental)
11. Sk. Class I
Grade 2
Non
Cleft
Side
Cleft
Side
Grade 3
Mild Sk. Class III
Edge to Edge
Grade 4(a)
(b)
Sk. Class III
One or both side anterior
crossbite
One or both side anterior
crossbite. Central incisor
may or may not touch
lowers
12. Good Anterior and
Posterior Palatal Height
with minor surface
irregularities
Grade 1
Grade 2
Moderate anterior and
posterior Palatal Height
with moderate surface
irregularities
Grade 3
Severe defect in height with
gross surface irregularities with
hour-glass like arch
constriction
EUROCRAN index ( Palatal Morphology)
13. BACKGROUND OF STUDY
• In Pakistan, one child in every 523 livebirths suffers from some
form of clefting.
• Treatment outcome of any type of CLP in Pakistani population
has never been documented.
• There is a lack of knowledge regarding the treatment outcome
in Pakistani population.
14. JUSTIFICATION OF STUDY
• Facilitate decision making and modification of treatment
planning. (Orthognathic & Surgical modalities)
• Form a database for future comparative studies.
• Reduce treatment cost.
15. GENERAL OBJECTIVES
• To determine the treatment outcome based on Dental Arch
Relationships in Pakistani Non-Syndromic Total Unilateral Cleft
Lip and Palate patients (TUCLP) using EUROCRAN index
16. SPECIFIC OBJECTIVES
• To determine the distribution of favorable/unfavorable treatment
outcome by using the EUROCRAN yardstick.
• To evaluate the association of the pre-natal (sex, family history
of cleft, and side of cleft) and post-natal treatment factors
(cheiloplasty and palatoplasty) with the treatment outcome.
17. RESEARCH QUESTION
• What is the prevalence of favorable and unfavorable treatment
outcome among Pakistani population?
• Is there an association among the pre & post-natal factors and
treatment outcome (dependent variable)?
18. NULL HYPOTHESES
• There is no association among the pre & post-natal factors and
treatment outcome.
19. METHODOLOGY
Ethical Approval was obtained from Human Research Ethics
Committee (USM/JEPeM/15050166)
Study Design
• It is a retrospective observational analytical study.
Source population
• Pakistani non-syndromic children having total unilateral cleft lip
and palate
Sampling method
• Collection of dental models from archives
20. SAMPLE SIZE CALCULATION
• Sample size was calculated using following formula (Lwanga
and Lemeshow, 1991);
• n = ﴾Z/d)²×P(1-P)
• required sample size, n
• level of confidence, Z = 1.96 (level of significance = 0.05)
• Absolute precision, d = 0.09 (9%)
• P is estimated proportion of individuals in the sample with the characteristic of interest, P=0.317
(Alam et al., 2008; Zreaqat et al., 2009)
• Therefore, the required sample size (n) was 102.
21. No Alveolar Bone
Graft (ABGs) or
Ortho
Non Syndromic TUCLP patients
7-10 years
of age
Primary lip and palate
repair has been done
Subjects with other types of CLP
defects
EXCLUSION
CRITERIA
INCLUSION
CRITERIA
Incomplete or Syndromic Clefts
(Dugas, 2010)
22. DATA COLLECTION
101 pairs of Dental
models were
collected from
archives
1
Conduction of
calibration courses
for observing
individuals
2
Single blinding by
random number
allotment to each
dental model
3
Statistical analysis
and interpretation
using SPSS 22.0
6
2-week interval
between instances
to eliminate
memory bias
5
Five observers
graded the models
at two instances
4
24. STATISTICAL ANALYSES
Inter & Intra Examiner Agreement
Correlation of dependent
variables and outcome
Association of variables that
affect outcome
Exploratory
Analysis to assess
predictability of
variable
Kappa Statistics
Chi-Square
Crude Logistic
Regression
Backward Logistic
Regression
25. RESULTS
• Kappa values between the first and second instance of
observations for dental grading by each examiner ranged from
0.606-0.778 that show good intra-examiner agreement
• Kappa values for the agreement of observations for palatal
morphology grading between both examiners were 0.574-0.969,
that show moderate to very good inter-examiner agreement
26. GRADING BASED ON EUROCRAN
19
42
40
Excellent Fair Poor
Palatal morphology
6
29
53
13
Excellent Good Fair Poor
Dental grading
Mean score ± SD = 2.72±0.76 Mean score ± SD = 2.20±0.73
28. CHARACTERISTIC DISTRIBUTION
24
11 13
22 22
13
29
6
30
5
34 32
17
49
44
22
36
30
40
26
Male Female Yes No Left Right Millard Mod.
Millard
VL VY
Gender Family history Cleft Side Cheiloplasty Palatoplasty
Favorable Unfavorable
Frequency
in
numbers
P-Value .099 .233 .702 .005** .009**
BASED ON DENTAL GRADING
29. 9 10
6
13
15
4
10 9
14
5
25
17
13
29 28
14
28
14
33
9
24
16
11
29
23
17
27
13
23
17
Male Female Yes No Left Right Millard Mod.
Millard
VL VY
Gender Family history Cleft Side Cheiloplasty Palatoplasty
1 2 3
CHARACTERISTIC DISTRIBUTION
Frequency
in
numbers
P-Value .263 .616 .925 .106 .494
BASED ON PALATAL MORPHOLOGY
30. UNADJUSTED LOGISTIC REGRESSION
Variables Crude ORa 95% CIb p-value
Gender
Male 1.00
Female 1.743 .649, 4.679 .270
Family history
of cleft
Yes 1.00
No 2.525 .907, 7.028 .076*
Side of Cleft
Left 1.00
Right .838 .305, 2.297 .731
Cheiloplasty
Millard 1.00
Modified Millard 4.468 1.510, 13.216 .007**
Palatoplasty
Von Langenbeck 1.00
VY pushback 3.468 1.114, 10.797 .032**
a. Crude odds ratio
b. Confidence Interval set at 95%
31. ADJUSTED: BACKWARD STEPWISE
Variables Adjusted ORa 95% CIb p-value
Family History
of Cleft
Yes 1
No 2.374 .872, 6.462 .091
Cheiloplasty
Millard 1
Modified Millard 4.518 1.533, 13.313 .006**
Palatoplasty
Von Langenbeck 1
VY pushback 3.666 1.203, 11.175 .022**
a. Crude odds ratio
b. Confidence Interval set at 95%
Five variables were entered at Step 1
32. DISCUSSION
• Here we assessed 101 cases of total unilateral cleft
phenotype only, which is in comparison the largest
sample size for single cleft phenotype.
• We found a significant association of two post-natal
factors (cheiloplasty and palatoplasty) with the
treatment outcome.
33. DISCUSSION
STUDY POPULATION NUMBER MEAN (SD) REFERENCE
DUTCH 97 1.97 (0.88) (Fudalej et al., 2011)
SWISS 33 2.50 (1.2) (Mueller et al., 2012)
POLISH 61 2.58 (0.92) (Fudalej et al., 2011)
PAKISTAN 101 2.72 (0.76) CURRENT STUDY
BASED ON DENTAL GRADING
34. DISCUSSION
STUDY POPULATION NUMBER MEAN (SD) REFERENCE
DUTCH 97 1.96 (0.55) (Fudalej et al., 2011)
SWISS - - (Mueller et al., 2012)
POLISH 61 1.79 (0.43) (Fudalej et al., 2011)
PAKISTAN 101 2.20 (0.73) CURRENT STUDY
BASED ON PALATAL MORPHOLOGY
35. DISCUSSION
• Association studies using other indices have been
published, however, till date the effect of prenatal and
postnatal factors using EUROCRAN index has not
assessed.
• We compare our findings with the literature available
for individual lip and palate repair techniques.
ASSOCIATION OF INDEPENDENT VARIABLES
36. DISCUSSION
• We found that Modified Millard technique had four times higher
odds of producing unfavorable results as compared to
conventional Millard technique.
• This can be attributed to the excessive tension generated as a
result of relatively tighter closure of cleft lip leading to anterior
maxillary constriction.(Farronato et al., 2014)
EFFECTS OF CHEILOPLASTY
38. DISCUSSION
• We found that VY pushback technique had three time
higher odds of producing unfavorable results as
compared to VL technique.
EFFECTS OF PALATOPLASTY
40. CONCLUSIONS
• Based on both modules of EUROCRAN index, this
study found a higher frequency of unfavorable
treatment outcome in TUCLP patients
• Significant associations of cheiloplasty and
palatoplasty techniques with the treatment outcome
were detected
41. LIMITATIONS OF STUDY
• The design of present study, limits the discussion to a
specific instance rather than a time period.
• Certain aspects of treatment like, surgeons’ skill, tissue
growth response, defect severity could not be
assessed in this design.
• These additions can certainly facilitate the
understanding and lead to better treatment planning.
42. FUTURE RECOMMENDATIONS
• There is a need for longitudinal assessment of CLP
from infancy to adulthood.
• Radiographic assessment and predictions can play a
significant role in treatment planning.
43. CLINICAL RELEVANCE
• We identified an evident lack of adaptation to the
recent protocols and techniques for management of
CLP patients
• The data will serve as a baseline for future
comparative studies
• Facilitate surgeons and researchers to modify
management protocols and select best techniques
available.
44. REFERENCES
Alam, M. K., Kajii, T. S., Koshikawa-Matsuno, M., Sugawara-Kato, Y., Sato, Y. & Iida, J. (2008). Multivariate analysis of
factors affecting dental arch relationships in Japanese unilateral cleft lip and palate patients at Hokkaido University
Hospital. Orthodontic Waves, 67(2), 45-53.
Bishara, S. E. & Mary Tharp, R. (1977). Effects of von Langenbeck palatoplasty on facial growth. Angle Orthodontist, 47(1),
34-41.
Chan, K. T., Hayes, C., Shusterman, S., Mulliken, J. B. & Will, L. A. (2003). The effects of active infant orthopedics on
occlusal relationships in unilateral complete cleft lip and palate. Cleft Palate-Craniofacial Journal, 40(5), 511-517.
Dugas, G. (2010). Intercenter Comparison of Treatment Outcome in Patients with Complete Unilateral and Bilateral Cleft
Lip and Palate: Analysis of Craniofacial Form, University of Toronto, Ontario, Canada. Available
from:https://tspace.library.utoronto.ca/bitstream/1807/18270/1/Dugas_Gregory_S_200911_MSc_thesis.pdf (Accessed on
April 20, 2016).
Farronato, G., Cannalire, P., Martinelli, G., Tubertini, I., Giannini, L., Galbiati, G. & Maspero, C. (2014). Cleft lip and/or
palate: review. Minerva Stomatologica, 63(4), 111-126.
Fudalej, P., Katsaros, C., Bongaarts, C., Dudkiewicz, Z. & Kuijpers-Jagtman, A. M. (2011). Dental arch relationship in
children with complete unilateral cleft lip and palate following one-stage and three-stage surgical protocols. Clinical Oral
Investigations, 15(4), 503-510.
Fudalej, P., Katsaros, C., Dudkiewicz, Z., Offert, B., Piwowar, W., Kuijpers, M. & Kuijpers-Jagtman, A. (2012). Dental arch
relationships following palatoplasty for cleft lip and palate repair. Journal of Dental Research, 91(1), 47-51.
45. REFERENCES
Kawamoto Jr, H. K. (1979). Correction of major defects of the vermilion with a cross-lip vermilion flap. Plastic and
Reconstructive Surgery, 64(3), 315-318.
Krause, C. J., Tharp, R. F. & Morris, H. L. (1976). A comparative study of results of the von Langenbeck and the VY
pushback palatoplasties. Cleft Palate Journal, 13(1), 11-19.
Lwanga, S. K. & Lemeshow, S. (1991). Sample size determination in health studies: a practical manual. University of
Michigan: World Health Organization, 21-33.
Millard, D. R. (1968). Extensions of the rotation-advancement principle for wide unilateral cleft lips. Plastic and
Reconstructive Surgery, 42(6), 535-544.
Mueller, A. A., Zschokke, I., Brand, S., Hockenjos, C., Zeilhofer, H.-F. & Schwenzer-Zimmerer, K. (2012). One-stage cleft
repair outcome at age 6-to 18-years–a comparison to the Eurocleft study data. British Journal of Oral and Maxillofacial
Surgery, 50(8), 762-768.
Randall, P. (1959). A triangular flap operation for the primary repair of unilateral clefts of the lip. Plastic and Reconstructive
Surgery, 23(4), 331-347.
Tennison, C. W. (1952). The repair of the unilateral cleft lip by the stencil method. Plastic and Reconstructive Surgery, 9(2),
115-120.
Witzel, M. A., Clarke, J. A., Lindsay, W. K. & Thomson, H. G. (1979). Comparison of results of pushback or von
Langenbeck repair of isolated cleft of the hard and soft palate. Plastic and Reconstructive Surgery, 64(3), 347-352.
Zreaqat, M. e., Hassan, R. & Halim, A. S. (2009). Dentoalveolar relationships of Malay children with unilateral cleft lip and
palate. Cleft Palate-Craniofacial Journal, 46(3), 326-330.
46. Thank You
Transforming Higher Education For A Sustainable Tomorrow
Contact: Anas Imran Arshad email: anas.i@live.com
Editor's Notes
GOOD Morning and peace be upon u all , I am Dr. Anas Imran and I am a Masters student in Universiti SM…
Ill be discussing the ASSESSMENT OF POST-TREATMENT OUTCOME OF PAKISTANI CHILDREN HAVING
TOTAL UNILATERAL CLEFT LIP AND PALATE USING EUROCRAN INDEX
Clinically, Cleft lip can be defined as a lack of fusion of upper lip
And cleft palate when the hard and soft palate are involved, it becomes total cleft lip and palate when they occur in combination
However, embryologically CLP is classified as A isolated cleft lip, B isolated cleft palate, C complete unilateral or D complete bilateral
a multifactorial origin has been suggested
Multiple genetic linkages have been found and environmental factors have also been strongly associated to affect the pregnant women……
Like teratogens for example smoking, alcohol or drug abuse…..
Infections during pregnancy or Excess ingestion of some micronutrients or medicinal abuse have also been reported
TREATMENT REQUIRES AN INTERDISCIPLINARY APPROACH …. Surgeries … click
. HOWEVER WE ARE FOCUSSING ON FINDING THE OUTCOMES OF PRIMARY LIP AND PALATE SURGERIES TO ENSURE
BETTER AND PREDICTABLE OUTCOMES
THERE ARE VARIOUS TECHNIQUES OF LIP REPAIR (CHEILOPLASTY) AND
different palatal repair (palatoplasty) techniques which can be used according to preference….
I am presenting EUROCRAN index as it was a specific objective in my Masters Project. However we included all three indices as part of final theses.
Eurocran INDEX has two components one is based on apical base relationships and the other on palatal surface morphology (CLICK)
Dental component has four grades
Which are based on subjective assessment of apical base relationship
According to palatal morphology … there are 3 grades
Which are based on surface defects and palatal height
In Pakistan, one child in every 523 livebirths suffers from some form of clefting. CLICK
Treatment outcome of any type of CLP in Pakistani population has never been documented. CLICK
There is a lack of knowledge regarding the treatment outcome in Pakistani population.
By documenting the influence of specific techniques of
primary surgical repair on treatment outcome we facilitate decision making. Click
Form a database for further studies
To reduce treatment cost by
timely intervention on the basis of outcome of the cleft
to avoid any complex orthodontic or orthognathic surgical procedures in future. Click
OUR main obj is to determine the treatment outcome based on DAR in PAKISTANI NON SYNDROMIC TUCLP PATIENT USING EUROCRAN INDEX
To determine the distribution of favorable/unfavorable treatment outcome CLICK
To evaluate the association of the pre-natal and post-natal factors with the treatment outcome.
What is the prevalence of favorable and unfavorable treatment outcome among Pakistani population? CLiCK
Is there an association among the independent variables and treatment outcome (dependent variable)?
Null hypothese states that there is no association
ETHICAL APPROVAL WAS OBTAINED FOR THIS RETROSPECTIVE STUDY. CLICK
SOURCE POPULATION WAS PAKISTANI NON-SYDROMIC CHILDREN HAVING TUCLP. CLICK
MODELS WERE COLLECTED FROM ARCHIVES OF CLEFT REFERRAL CENTERS.
SAMPLE SIZE WAS CALCULATED BASED ON FOLLOWING FORMULA AFTER CONSULTING BIOSTATISTICIAN..
INCLUSION CRITERIA WAS BASED ON CURRENT LITERATURE SEARCH
101 dental models were collected CLICKCalibaration courses were conducted CLICKSingle blinding by random number assignment CLICKFive observers graded at two instance CLICK2 week interval to eliminate memory bias CLICK
Statistical analysis were performed
Research tools were Dental models, history sheets and EUROCRAN index
Kappa statistics were applied to assess intra and inter examiner agreements
Correlation of Dependent variables were checked by chi-square tests
Association of factors affecting were evaluated by crude logistic regression
Exploratory analyses through backward stepwise Logistic regression were performed
SPSS v 22 was used
Significance level will be set at 0.05
Kappa values indicated good intraexaminer agreement between the two instances
and moderate to very good interexaminer agreements
A mean score of 2.72 was computed based on dental grading
And 2.20 for palatal surface morphology
DICHOTOMIZATION OF DENTAL GRADING WAS PERFORMED WHERE GROUP 1 and 2 were termed favorable and 3 and 4 were termed unfavorable…..
CHI SQUARE ANALYSIS SUGGESTED A SIGNIFICANT ASSOICATION OF CHEILO AND PALATO with the outcome groups BASED ON DENTAL grading
However, CHI SQUARE ANALYSIS DID NOT REVEAL ANY SIGNIFICANT ASSOICATIONS BASED ON PALATAL MORPHOLOGY
UNADJUSTED LOGISTIC REGRESSION indicated a weak association of family history and significant association of cheilo and palatoplasty techniques.
Null hypothesis was rejected, and significant associations cheiloplasty and palatoplasty techniques)
with the treatment outcome were identified by final model
we assessed 101 cases of total unilateral cleft phenotype only, which is in comparison the largest sample size for single cleft phenotype.
We found a significant association of two post-natal factors (cheiloplasty and palatoplasty) with the treatment outcome.
Based on dental grading, the mean score was comparatively poor than the Dutch populations but Polish and Swiss populations had comparable scores (Fudalej et al., 2011; Mueller et al., 2012)
Based on palatal surface morphology, the mean score was worse than Polish and DUTCH populations, whereas scores for DUTCH population were not revealed
Association studies using other indices have been published, however, till date the effect of prenatal and postnatal factors using EUROCRAN index has not assessed. CLICK
We compare our findings with the literature available for individual lip and palate repair techniques.
We found that Modified Millard technique had four times higher odds of producing unfavorable results as compared to conventional Millard technique. CLCIK
This can be attributed to the excessive tension generated as a result of relatively tighter closure of cleft lip leading to anterior maxillary constriction.(Farronato et al., 2014)
the excessive tension generated as a result of relatively tighter closure due to modification in incision lines can result in excess pressure.
But conventional technique is associated with shorter lip length.. Which could justify the use of modified techniques
We found that VY pushback technique had three time higher odds of producing unfavorable results as compared to VL technique.
While comparing the two techniques CLICK
VL results in minimum scarring whereas VY technique leave large exposed surface resulting in bigger scar formation CLICK
IN VL technique flaps have limited mobility whereas VY facilitates great mobility of flaps. CLICK
One theory of selecting VY could be a larger initial defect size. CLICK
Speech problems have been associated with VL whereas VY frequently results in fistula formation.