5. 2. Proliferation
● Ectoderm forms a plate called a neural plate, then a fold
called the neural crest
● Finally curves into a tube, called the neural tube
○ Eventually forming the CNS (spine and brain)
● Spina bifida is a disorder in which the neural tube fails
to close; underdeveloped spine, no cure
● Progenitors in the center of the tube synthesize neurons
○ Ex: radial glial cells
● If they are destroyed, have effects on brain development
(microcephaly in Zika)
6.
7. - 3 to 4 weeks after baby’s conception
- hindbrain, midbrain, & forebrain form
- Radial migration: “inside-out”, oldest cells form deepest
layer of cortex and youngest cells form outer layer
- Alcohol, drugs, radiation prevent proper migration of
neurons → leads to misplacement of cells & epilepsy
3. Migration
8.
9. 4. Making Connections
● Enables senses
● Dependent on environmental
interactions
● Become interconnected through:
○ Growth of dendrites
○ Growth of axons
● Growth cones (enlargement of
axon’s tips) explore environment
as destination is sought
○ Bear molecules that serve as
receptors for environmental cues
○ Tells growth cones what to do
● Axons form connections at
synapse
10.
11. 5. Myelination
● Myelination - wrapping of
axons, surrounded by glia
● Increases speed of neural
impulses by 100x
● Saltatory conduction is
responsible for increased
speed - nodes of Ranvier
● Process of myelination
occurs throughout lifespan
12. 6. Paring Back
● Half the neurons produced in
development stages survive to
adulthood
○ destroyed through apoptosis
(programmed cell death)
○ Only if neurons fail to receive
life-sustaining chemical factors
called trophic factors
● Excess connections between neurons
○ Active ones stay
○ Unused ones are lost - “pruning”
13.
14.
15.
16. Critical periods
● Genes + environment are key to neural
circuits
● Critical periods: brain must have
critical experiences early in development
● After critical period…
○ Some connections are lost
○ Some remain...these are stronger →
make cognitive maps
● Injury or deprivation of events can be
harmful
○ Ex. Loss of vision
● Heightened activity may increase certain
disorders
○ Ex. Epilepsy
● ~25 years old is when the frontal lobe
stops maturing
17. Brain plasticity
● Ability of brain to modify itself and adapt
to change
● Experience-expectant plasticity:
integration of environmental stimuli into
normal patterns of development
○ Ex: baby birds must hear adult birds
sign so they can learn pitch
● Hope to be used with learning disabilities
in children
18. Have You Heard…
⮚ Teens are :
⮚ Reckless?
⮚ Risky Behavior?
⮚ Mood Swings
⮚ Easily influenced?
⮚ Poor Decision Making?
29. “On the one hand, adolescents are more apt to experiment and make
poor choices because their brains are still developing, but they are
also more able than adults to learn from their mistakes and alter
their perspectives,” says Dr. Jonathan Romain, a pediatric
neuropsychologist. “I see adolescence as a period of great potential
for growth and development.”
In SUmmary
Parents play a crucial role in helping teens talk through consequences
and decision making.
Parents :: Be honest, did you ever do anything risky as a teen? Chances are your answer is yes!
The brain is a plastic organ
Now have you every heard of or noticed, that children and teenagers are able to learn things more quickly? That they can pick up on languages quicker and tend to consume knowledge more easily at a much faster rate. This is because the brains of children and adolescents is more plastic, enabling them to gain more information easily as the brain rewires to help them store these as memories.
Now the teenage years are especially formative years. This is due to development in a region of the brain known as the prefrontal cotex. This is a part of the brain responsible for decision making, responsibility, emotion, and helps set a filter on an individual’s mouth. While almost the entire brain is still developing at this point, it is the prefrontal cortex that especially is growing and changing throughout adolescence with every action we take or every influence we get.
Now think about it like this: the prefrontal cortex is in a way “unstable for teenagers”, it is changing as a response to everything. And since it is unstable, it can sometimes inhibit a teenager from making the right decision.
When they are in the face of peer pressure, they will remember that falling victim to it is not the most responsible decision at all.
When they see someone experiencing emotional difficulty, or themselves are victim of the same problem, they should be able to talk to that friend and provide support, or having the knowledge that what they are feeling Is because of brain development and is most often not a fault of their own, they will feel less embarrassed and more open to talking to a counselor which will
Go talk to whoever is closest to you
Teacher
Friend
Parent
Even doctors
It is very important that teenagers know about the changes that their brain is going through, since being conscious about these changes will help them be prepared for all the adverse side effects that this development leads to. This is the goal of the Teen Brains Initiative. We want to spread knowledge and awareness of the brain to high schoolers all across the country
teens’ prefrontal cortex is going through dramatic development; this area of the brain is involved with planning, social interactions, and stopping yourself from saying something unpleasant.