This document summarizes research on training load management in football. It discusses how monitoring training load and analyzing the data can inform decision making to find the optimal load for each player. While acute:chronic workload ratios are often used, the evidence for their ability to prevent injuries is limited due to poor study quality and lack of randomized controlled trials. Training load must be considered together with other individual factors, and load management aims to balance training and recovery rather than precisely predict or prevent health problems.
Improving epidemiological research: avoiding the statistical paradoxes and fa...Maarten van Smeden
Keynote at Norwegian Epidemiological Association conference, October 26 2022. Discussing absence of evidence fallacy, Table 2 fallacy, Winner's curse and Stein's paradox.
Prediction, Big Data, and AI: Steyerberg, Basel Nov 1, 2019Ewout Steyerberg
Title"Clinical prediction models in the age of artificial intelligence and big data", presented at the Basel Biometrics Society seminar Nov 1, 2019, Basel, by Ewout Steyerberg, with substantial inout from Maarten van Smeden and Ben van Calster
Algorithm based medicine: old statistics wine in new machine learning bottles?Maarten van Smeden
The document summarizes a seminar presentation given by Maarten van Smeden on algorithm based medicine and machine learning. Some key points made in the presentation include: the terminology of artificial intelligence often refers to machine learning or algorithms in medical research; examples are given of areas where machine learning has performed well, such as detecting diabetic retinopathy and lymph node metastases; examples are also provided of where machine learning has done poorly, such as predicting recidivism and mortality; and the sources of prediction error from machine learning models are discussed.
How to combine results from randomised clinical trials on the additive scale with real world data to provide predictions on the clinically relevant scale for individual patients
This document summarizes a presentation given by Maarten van Smeden on explainable AI in medicine. Some key points from the presentation include:
- Van Smeden discusses several questions around AI in medicine, including whether AI is truly intelligent, if it is just new statistics, if it can explain its predictions, and if it is better at predictions.
- He notes the field of AI in medicine is very heterogeneous, using different types of data and models. Prediction models aim to predict outcomes but may not explain causal relationships.
- True explanatory models that can determine cause and effect are challenging, as AI systems cannot infer causal relationships from data alone without explicit domain knowledge.
- The ability of AI
Analysis of the Boston Housing Data from the 1970 censusShuai Yuan
This document analyzes the Boston housing data from 1970 using R. It examines the relationships between variables using scatterplots and correlation. Various regression models are tested to analyze properties of the data. Model selection methods like forward selection, backward selection, and information criteria are used to identify the best fitting model. The selected model is then used to compute statistics like SSPE on a subset of the data.
Improving epidemiological research: avoiding the statistical paradoxes and fa...Maarten van Smeden
Keynote at Norwegian Epidemiological Association conference, October 26 2022. Discussing absence of evidence fallacy, Table 2 fallacy, Winner's curse and Stein's paradox.
Prediction, Big Data, and AI: Steyerberg, Basel Nov 1, 2019Ewout Steyerberg
Title"Clinical prediction models in the age of artificial intelligence and big data", presented at the Basel Biometrics Society seminar Nov 1, 2019, Basel, by Ewout Steyerberg, with substantial inout from Maarten van Smeden and Ben van Calster
Algorithm based medicine: old statistics wine in new machine learning bottles?Maarten van Smeden
The document summarizes a seminar presentation given by Maarten van Smeden on algorithm based medicine and machine learning. Some key points made in the presentation include: the terminology of artificial intelligence often refers to machine learning or algorithms in medical research; examples are given of areas where machine learning has performed well, such as detecting diabetic retinopathy and lymph node metastases; examples are also provided of where machine learning has done poorly, such as predicting recidivism and mortality; and the sources of prediction error from machine learning models are discussed.
How to combine results from randomised clinical trials on the additive scale with real world data to provide predictions on the clinically relevant scale for individual patients
This document summarizes a presentation given by Maarten van Smeden on explainable AI in medicine. Some key points from the presentation include:
- Van Smeden discusses several questions around AI in medicine, including whether AI is truly intelligent, if it is just new statistics, if it can explain its predictions, and if it is better at predictions.
- He notes the field of AI in medicine is very heterogeneous, using different types of data and models. Prediction models aim to predict outcomes but may not explain causal relationships.
- True explanatory models that can determine cause and effect are challenging, as AI systems cannot infer causal relationships from data alone without explicit domain knowledge.
- The ability of AI
Analysis of the Boston Housing Data from the 1970 censusShuai Yuan
This document analyzes the Boston housing data from 1970 using R. It examines the relationships between variables using scatterplots and correlation. Various regression models are tested to analyze properties of the data. Model selection methods like forward selection, backward selection, and information criteria are used to identify the best fitting model. The selected model is then used to compute statistics like SSPE on a subset of the data.
The document summarizes the recommendations of an IOM committee on establishing a national program for clinical effectiveness research. The committee recommended designating a single entity to produce credible, unbiased information through systematic reviews and practice guidelines developed according to standard processes. This entity would set research priorities according to criteria like improving health outcomes and reducing disease burden. The committee proposed a hybrid model where this entity develops standards but existing groups conduct reviews, to reduce duplication and engender trust.
This document discusses quality improvement in healthcare. It begins by posing questions about defining quality, what quality improvement is, and how quality can be improved. It then discusses the safety paradox in healthcare - that despite highly trained staff and technology, errors are common and patients are frequently harmed. Several studies on adverse event rates in hospitals are summarized. The document discusses concepts for safety and quality improvement like reliability, variation, measurement, and change management. It provides examples of quality improvement tools and approaches like process mapping, care bundles, measurement, and the PDSA (Plan-Do-Study-Act) cycle. Overall, the document provides an overview of key issues and approaches related to quality and safety in healthcare.
Educational Research 102: Selecting the Best Study Design for your Research Q...fnuthalapaty
This document discusses selecting the appropriate study design for an educational research question. It begins by describing different types of research including empirical vs non-empirical and basic vs applied research. It then covers quantitative research designs like experimental, quasi-experimental, causal-comparative and correlational studies. Key aspects of these designs like control groups, randomization, pre-post testing are explained. Threats to internal and external validity and steps in the research process are also summarized. The document aims to help researchers understand how to match their research question to the best fitting study design.
Decoding human physiology: a decade of researchMarco Altini
Marco Altini is a machine learning researcher interested in applying the field to healthcare and sports applications. His work focuses on using physiological, behavioral, and lifestyle data to advance understanding of health and performance, with the goal of empowering individual decision making. Key areas of his research include developing accurate wearable sensors to measure physiology during free living, personalizing models through unsupervised normalization, and analyzing insights from large user-generated datasets. The overarching aim is to provide individuals with clinical-grade data and tools to inform their health and training decisions.
Extending A Trial’s Design Case Studies Of Dealing With Study Design IssuesnQuery
This document discusses several case studies of dealing with complex study design issues in clinical trials, including non-proportional hazards, cluster randomization, and three-armed trials. The agenda outlines topics on non-proportional hazards modeling and sample size considerations, cluster randomized and stepped-wedge designs, and methods for analyzing data from three-armed trials that include experimental, reference, and placebo groups. Worked examples are provided to illustrate sample size calculations and statistical approaches for each of these complex trial design scenarios.
The document outlines a postgraduate certificate in moving and handling (M&H) at Auckland University of Technology (AUT). Musculoskeletal disorders are a major cause of disability and work-related illness, especially in healthcare. The certificate aims to upskill healthcare workers in ergonomics, risk assessment, and evidence-based M&H practices. It consists of three papers taught over 15 months to align M&H in New Zealand with international standards. An evaluation will assess how the certificate improves M&H practices and reduces workplace injuries in healthcare organizations.
This study examined whether early improvement in neck function predicted overall response to a cervical strengthening program for chronic neck pain. 214 patients completed a 3-week strengthening program and were assessed for changes in neck disability index (NDI) scores. Patients with a positive change in NDI scores after 3 weeks had a 25 times greater odds of overall improvement. Early improvement likely reflects motor skill acquisition rather than muscle hypertrophy. While early responders saw small additional gains, continued strengthening may provide further benefits like reduced muscle co-activation.
A Graduate Critical Appraisal Assignment for Athletic TrainingJohn Parsons
1) The document discusses a graduated critical appraisal assignment used to teach athletic training students how to critically analyze research studies. 2) It involves having students start with annotating articles and working up to crafting clinical questions, analyzing levels of evidence, and fully critically appraising studies. 3) The assignment is meant to help students develop skills in evidence-based practice and preparing them for real-world clinical decision making.
This document provides an overview of evidence-based medicine (EBM). It defines EBM as integrating the best available research evidence with clinical expertise and patient values. It notes that the amount of medical evidence is increasing exponentially, making it difficult for physicians to keep up-to-date. The document outlines the 5 steps of EBM practice and emphasizes the importance of critically appraising evidence for validity, importance, and applicability to patients. It also discusses assessing the levels, strength, and quality of evidence to determine the strength of recommendations for clinical practice guidelines.
Walden University
NURS 6050 Policy and Advocacy for Improving Population Health
Module 3
IntroductionResourcesDiscussionAssignmentMy Progress Tracker
NURS 6050 Policy and Advocacy for Improving Population Health | Module 3
IntroductionResourcesDiscussionAssignment☰Menu Walden University
NURS 6050 Policy and Advocacy for Improving Population Health
Module 3
IntroductionResourcesDiscussionAssignmentMy Progress Tracker
NURS 6050 Policy and Advocacy for Improving Population Health | Module 3
IntroductionResourcesDiscussionAssignment☰Menu× NURS 6050 Policy and Advocacy for Improving Population Health Back to Course Home Course Calendar Syllabus Course Information Resource List Support, Guidelines, and Policies Module 1 Module 2 Module 3 Module 4 Module 5 Module 6
Exit and return to the Blackboard App menu to access other tools, assessments, and content. Pull down, then click the "X" button at the top left corner of your mobile device.
Photo Credit: Getty Images/iStockphotoModule 3: Regulation (Weeks 5-6)
Laureate Education (Producer). (2018). Regulation [Video file]. Baltimore, MD: Author.
Rubic_Print_FormatCourse CodeClass CodeAssignment TitleTotal PointsLDR-463LDR-463-O501Topic 5 Journal Entry30.0CriteriaPercentageUnsatisfactory (0.00%)Less Than Satisfactory (65.00%)Satisfactory (75.00%)Good (85.00%)Excellent (100.00%)CommentsPoints EarnedContent100.0%Response to Journal Entry Prompt80.0%Response to the journal entry prompt is not present.Response to the journal entry prompt is incomplete or incorrect.Response to the journal entry prompt is complete but lacks relevant detail.Response to the journal entry prompt is thorough and contains substantial supporting details.Response to the journal entry prompt is complete and contains relevant supporting details.Mechanics of Writing includes spelling, punctuation, grammar, and language use.20.0%Frequent and repetitive mechanical errors distract the reader. Inconsistencies in language choice (register) or word choice are present. Sentence structure is correct but not varied.Surface errors are pervasive enough that they impede communication of meaning. Inappropriate word choice or sentence construction is used.Some mechanical errors or typos are present, but they are not overly distracting to the reader. Correct and varied sentence structure and audience-appropriate language are employed.Prose is largely free of mechanical errors, although a few may be present. The writer uses a variety of effective sentence structures and figures of speech.Writer is clearly in command of standard, written, academic English.Total Weightage100%
Walden University
NURS 6050 Policy and Advocacy for Improving Population Health ...
The effectiveness of exercise interventions to prevent sports injuriesFernando Farias
Strength training reduced sports injuries to less
than one-third. We advocate that multiple exposure interven-
tions should be constructed on the basis of well-proven single
exposures and that further research into single exposures, par-
ticularly strength training, remains crucial. Both acute and
overuse injuries could be significantly reduced, overuse injuries
by almost a half.
This document discusses big data in healthcare and physical therapy. It provides an overview of ATI's use of big data through its large patient outcomes registry, which includes over 800 variables and has been accepted into federal registries. ATI leverages data on patient demographics, referrals, outcomes, satisfaction surveys, and costs to enhance care and outcomes. The challenges of evidence-based medicine in an era of big data are also examined, highlighting the need to reconcile evidence-based and precision approaches through standardized sharing of data.
The document describes the development of a situational judgment test (SJT) to assess teamwork skills in medical professionals. Key points:
- Existing teamwork assessments have limitations, so the study aimed to create a low-cost SJT. Researchers developed items based on teamwork examples from medical experts.
- The SJT measures five teamwork dimensions: communication, team structure, mutual support, leadership, and environmental awareness. Items were sorted into dimensions and revised for agreement.
- Data was collected from medical students and professionals to validate the SJT. Results showed the SJT differentiated students and professionals better than an existing teamwork measure.
- Further validation is needed, but the SJT shows potential
August 2014 in-service presentation for Spaulding Rehabiliation Hospital, Charlestown MA at the competition of clinical affiliation on the SCI unit. Review of current literature for improving evidence based practice.
The document summarizes a pilot of single session therapy that was conducted at the University of Cumbria. Key points:
- Referrals to the university's mental health and wellbeing team had been increasing year over year. The team implemented a pilot of single session therapy to help reduce wait times for students.
- Data was collected before and during the pilot to evaluate outcomes. The pilot appeared successful in reducing staff stress, shortening wait times for students, and maintaining or improving student outcomes and experience based on measures.
- Unexpected benefits included lower rates of students missing appointments and evidence that single session therapy helped improve mood and retention for some students. Overall, the pilot seemed to meet its goals of helping staff cope
Meditacion ayuda a la resitencia de enfermedades cerebralesRAUL TAYA PEREZ
This summary provides the key points from the document in 3 sentences:
The study investigated whether improvements in muscle strength and aerobic capacity (VO2peak) from progressive resistance training (PRT) mediated improvements in cognitive function for older adults with mild cognitive impairment. The results showed that PRT significantly improved upper body, lower body, and whole body strength more than a sham exercise control. Higher strength scores after PRT, but not changes in VO2peak, were significantly associated with improvements in cognition. Greater lower body strength gains partially mediated the effect of PRT on improving global cognition, but not executive function.
Training load monitoring can inform decisions at multiple levels of athlete management, from long-term season planning to in-session adjustments. At a long-term level, load monitoring can be used to understand an athlete's profile over multiple seasons, identify high stress periods, and plan for sport-specific demands. In the short-term, load data can help evaluate daily training plans, assess an athlete's response and progression, and determine if injury risks are elevated. While load data provides useful insights, it cannot predict injury on its own and should not be used in an overly risk-averse manner that restricts important training. Practitioners must consider numerous contextual factors for each athlete to properly interpret and apply load monitoring information.
This document outlines how the National Institute for Health and Care Excellence (NICE) uses cost-effectiveness analysis to inform reimbursement decisions in the UK. It discusses NICE's process and how it generally accepts interventions with an incremental cost-effectiveness ratio of less than £20,000-30,000 per quality-adjusted life year (QALY). The document emphasizes the important role of the EQ-5D questionnaire in NICE's decisions by allowing comparison of health outcomes. It addresses issues like collecting EQ-5D data, mapping from other measures, and potential limitations of EQ-5D for certain conditions.
The document discusses the importance of will and leadership in driving quality improvement efforts in healthcare. It notes that some clinicians express discomfort with quality improvement data and initiatives. It emphasizes that creating the right culture where people feel safe to change is important to encouraging improvement. Measurement is discussed as a key part of improvement work. Leadership must establish a clear mission and strategy to align improvement projects and individual goals. Auditing practices and implementing changes is part of the ongoing improvement cycle.
The document summarizes the recommendations of an IOM committee on establishing a national program for clinical effectiveness research. The committee recommended designating a single entity to produce credible, unbiased information through systematic reviews and practice guidelines developed according to standard processes. This entity would set research priorities according to criteria like improving health outcomes and reducing disease burden. The committee proposed a hybrid model where this entity develops standards but existing groups conduct reviews, to reduce duplication and engender trust.
This document discusses quality improvement in healthcare. It begins by posing questions about defining quality, what quality improvement is, and how quality can be improved. It then discusses the safety paradox in healthcare - that despite highly trained staff and technology, errors are common and patients are frequently harmed. Several studies on adverse event rates in hospitals are summarized. The document discusses concepts for safety and quality improvement like reliability, variation, measurement, and change management. It provides examples of quality improvement tools and approaches like process mapping, care bundles, measurement, and the PDSA (Plan-Do-Study-Act) cycle. Overall, the document provides an overview of key issues and approaches related to quality and safety in healthcare.
Educational Research 102: Selecting the Best Study Design for your Research Q...fnuthalapaty
This document discusses selecting the appropriate study design for an educational research question. It begins by describing different types of research including empirical vs non-empirical and basic vs applied research. It then covers quantitative research designs like experimental, quasi-experimental, causal-comparative and correlational studies. Key aspects of these designs like control groups, randomization, pre-post testing are explained. Threats to internal and external validity and steps in the research process are also summarized. The document aims to help researchers understand how to match their research question to the best fitting study design.
Decoding human physiology: a decade of researchMarco Altini
Marco Altini is a machine learning researcher interested in applying the field to healthcare and sports applications. His work focuses on using physiological, behavioral, and lifestyle data to advance understanding of health and performance, with the goal of empowering individual decision making. Key areas of his research include developing accurate wearable sensors to measure physiology during free living, personalizing models through unsupervised normalization, and analyzing insights from large user-generated datasets. The overarching aim is to provide individuals with clinical-grade data and tools to inform their health and training decisions.
Extending A Trial’s Design Case Studies Of Dealing With Study Design IssuesnQuery
This document discusses several case studies of dealing with complex study design issues in clinical trials, including non-proportional hazards, cluster randomization, and three-armed trials. The agenda outlines topics on non-proportional hazards modeling and sample size considerations, cluster randomized and stepped-wedge designs, and methods for analyzing data from three-armed trials that include experimental, reference, and placebo groups. Worked examples are provided to illustrate sample size calculations and statistical approaches for each of these complex trial design scenarios.
The document outlines a postgraduate certificate in moving and handling (M&H) at Auckland University of Technology (AUT). Musculoskeletal disorders are a major cause of disability and work-related illness, especially in healthcare. The certificate aims to upskill healthcare workers in ergonomics, risk assessment, and evidence-based M&H practices. It consists of three papers taught over 15 months to align M&H in New Zealand with international standards. An evaluation will assess how the certificate improves M&H practices and reduces workplace injuries in healthcare organizations.
This study examined whether early improvement in neck function predicted overall response to a cervical strengthening program for chronic neck pain. 214 patients completed a 3-week strengthening program and were assessed for changes in neck disability index (NDI) scores. Patients with a positive change in NDI scores after 3 weeks had a 25 times greater odds of overall improvement. Early improvement likely reflects motor skill acquisition rather than muscle hypertrophy. While early responders saw small additional gains, continued strengthening may provide further benefits like reduced muscle co-activation.
A Graduate Critical Appraisal Assignment for Athletic TrainingJohn Parsons
1) The document discusses a graduated critical appraisal assignment used to teach athletic training students how to critically analyze research studies. 2) It involves having students start with annotating articles and working up to crafting clinical questions, analyzing levels of evidence, and fully critically appraising studies. 3) The assignment is meant to help students develop skills in evidence-based practice and preparing them for real-world clinical decision making.
This document provides an overview of evidence-based medicine (EBM). It defines EBM as integrating the best available research evidence with clinical expertise and patient values. It notes that the amount of medical evidence is increasing exponentially, making it difficult for physicians to keep up-to-date. The document outlines the 5 steps of EBM practice and emphasizes the importance of critically appraising evidence for validity, importance, and applicability to patients. It also discusses assessing the levels, strength, and quality of evidence to determine the strength of recommendations for clinical practice guidelines.
Walden University
NURS 6050 Policy and Advocacy for Improving Population Health
Module 3
IntroductionResourcesDiscussionAssignmentMy Progress Tracker
NURS 6050 Policy and Advocacy for Improving Population Health | Module 3
IntroductionResourcesDiscussionAssignment☰Menu Walden University
NURS 6050 Policy and Advocacy for Improving Population Health
Module 3
IntroductionResourcesDiscussionAssignmentMy Progress Tracker
NURS 6050 Policy and Advocacy for Improving Population Health | Module 3
IntroductionResourcesDiscussionAssignment☰Menu× NURS 6050 Policy and Advocacy for Improving Population Health Back to Course Home Course Calendar Syllabus Course Information Resource List Support, Guidelines, and Policies Module 1 Module 2 Module 3 Module 4 Module 5 Module 6
Exit and return to the Blackboard App menu to access other tools, assessments, and content. Pull down, then click the "X" button at the top left corner of your mobile device.
Photo Credit: Getty Images/iStockphotoModule 3: Regulation (Weeks 5-6)
Laureate Education (Producer). (2018). Regulation [Video file]. Baltimore, MD: Author.
Rubic_Print_FormatCourse CodeClass CodeAssignment TitleTotal PointsLDR-463LDR-463-O501Topic 5 Journal Entry30.0CriteriaPercentageUnsatisfactory (0.00%)Less Than Satisfactory (65.00%)Satisfactory (75.00%)Good (85.00%)Excellent (100.00%)CommentsPoints EarnedContent100.0%Response to Journal Entry Prompt80.0%Response to the journal entry prompt is not present.Response to the journal entry prompt is incomplete or incorrect.Response to the journal entry prompt is complete but lacks relevant detail.Response to the journal entry prompt is thorough and contains substantial supporting details.Response to the journal entry prompt is complete and contains relevant supporting details.Mechanics of Writing includes spelling, punctuation, grammar, and language use.20.0%Frequent and repetitive mechanical errors distract the reader. Inconsistencies in language choice (register) or word choice are present. Sentence structure is correct but not varied.Surface errors are pervasive enough that they impede communication of meaning. Inappropriate word choice or sentence construction is used.Some mechanical errors or typos are present, but they are not overly distracting to the reader. Correct and varied sentence structure and audience-appropriate language are employed.Prose is largely free of mechanical errors, although a few may be present. The writer uses a variety of effective sentence structures and figures of speech.Writer is clearly in command of standard, written, academic English.Total Weightage100%
Walden University
NURS 6050 Policy and Advocacy for Improving Population Health ...
The effectiveness of exercise interventions to prevent sports injuriesFernando Farias
Strength training reduced sports injuries to less
than one-third. We advocate that multiple exposure interven-
tions should be constructed on the basis of well-proven single
exposures and that further research into single exposures, par-
ticularly strength training, remains crucial. Both acute and
overuse injuries could be significantly reduced, overuse injuries
by almost a half.
This document discusses big data in healthcare and physical therapy. It provides an overview of ATI's use of big data through its large patient outcomes registry, which includes over 800 variables and has been accepted into federal registries. ATI leverages data on patient demographics, referrals, outcomes, satisfaction surveys, and costs to enhance care and outcomes. The challenges of evidence-based medicine in an era of big data are also examined, highlighting the need to reconcile evidence-based and precision approaches through standardized sharing of data.
The document describes the development of a situational judgment test (SJT) to assess teamwork skills in medical professionals. Key points:
- Existing teamwork assessments have limitations, so the study aimed to create a low-cost SJT. Researchers developed items based on teamwork examples from medical experts.
- The SJT measures five teamwork dimensions: communication, team structure, mutual support, leadership, and environmental awareness. Items were sorted into dimensions and revised for agreement.
- Data was collected from medical students and professionals to validate the SJT. Results showed the SJT differentiated students and professionals better than an existing teamwork measure.
- Further validation is needed, but the SJT shows potential
August 2014 in-service presentation for Spaulding Rehabiliation Hospital, Charlestown MA at the competition of clinical affiliation on the SCI unit. Review of current literature for improving evidence based practice.
The document summarizes a pilot of single session therapy that was conducted at the University of Cumbria. Key points:
- Referrals to the university's mental health and wellbeing team had been increasing year over year. The team implemented a pilot of single session therapy to help reduce wait times for students.
- Data was collected before and during the pilot to evaluate outcomes. The pilot appeared successful in reducing staff stress, shortening wait times for students, and maintaining or improving student outcomes and experience based on measures.
- Unexpected benefits included lower rates of students missing appointments and evidence that single session therapy helped improve mood and retention for some students. Overall, the pilot seemed to meet its goals of helping staff cope
Meditacion ayuda a la resitencia de enfermedades cerebralesRAUL TAYA PEREZ
This summary provides the key points from the document in 3 sentences:
The study investigated whether improvements in muscle strength and aerobic capacity (VO2peak) from progressive resistance training (PRT) mediated improvements in cognitive function for older adults with mild cognitive impairment. The results showed that PRT significantly improved upper body, lower body, and whole body strength more than a sham exercise control. Higher strength scores after PRT, but not changes in VO2peak, were significantly associated with improvements in cognition. Greater lower body strength gains partially mediated the effect of PRT on improving global cognition, but not executive function.
Training load monitoring can inform decisions at multiple levels of athlete management, from long-term season planning to in-session adjustments. At a long-term level, load monitoring can be used to understand an athlete's profile over multiple seasons, identify high stress periods, and plan for sport-specific demands. In the short-term, load data can help evaluate daily training plans, assess an athlete's response and progression, and determine if injury risks are elevated. While load data provides useful insights, it cannot predict injury on its own and should not be used in an overly risk-averse manner that restricts important training. Practitioners must consider numerous contextual factors for each athlete to properly interpret and apply load monitoring information.
This document outlines how the National Institute for Health and Care Excellence (NICE) uses cost-effectiveness analysis to inform reimbursement decisions in the UK. It discusses NICE's process and how it generally accepts interventions with an incremental cost-effectiveness ratio of less than £20,000-30,000 per quality-adjusted life year (QALY). The document emphasizes the important role of the EQ-5D questionnaire in NICE's decisions by allowing comparison of health outcomes. It addresses issues like collecting EQ-5D data, mapping from other measures, and potential limitations of EQ-5D for certain conditions.
The document discusses the importance of will and leadership in driving quality improvement efforts in healthcare. It notes that some clinicians express discomfort with quality improvement data and initiatives. It emphasizes that creating the right culture where people feel safe to change is important to encouraging improvement. Measurement is discussed as a key part of improvement work. Leadership must establish a clear mission and strategy to align improvement projects and individual goals. Auditing practices and implementing changes is part of the ongoing improvement cycle.
Similar to Training load and injuries in football- lessons from research and practise (20)
EWOCS-I: The catalog of X-ray sources in Westerlund 1 from the Extended Weste...Sérgio Sacani
Context. With a mass exceeding several 104 M⊙ and a rich and dense population of massive stars, supermassive young star clusters
represent the most massive star-forming environment that is dominated by the feedback from massive stars and gravitational interactions
among stars.
Aims. In this paper we present the Extended Westerlund 1 and 2 Open Clusters Survey (EWOCS) project, which aims to investigate
the influence of the starburst environment on the formation of stars and planets, and on the evolution of both low and high mass stars.
The primary targets of this project are Westerlund 1 and 2, the closest supermassive star clusters to the Sun.
Methods. The project is based primarily on recent observations conducted with the Chandra and JWST observatories. Specifically,
the Chandra survey of Westerlund 1 consists of 36 new ACIS-I observations, nearly co-pointed, for a total exposure time of 1 Msec.
Additionally, we included 8 archival Chandra/ACIS-S observations. This paper presents the resulting catalog of X-ray sources within
and around Westerlund 1. Sources were detected by combining various existing methods, and photon extraction and source validation
were carried out using the ACIS-Extract software.
Results. The EWOCS X-ray catalog comprises 5963 validated sources out of the 9420 initially provided to ACIS-Extract, reaching a
photon flux threshold of approximately 2 × 10−8 photons cm−2
s
−1
. The X-ray sources exhibit a highly concentrated spatial distribution,
with 1075 sources located within the central 1 arcmin. We have successfully detected X-ray emissions from 126 out of the 166 known
massive stars of the cluster, and we have collected over 71 000 photons from the magnetar CXO J164710.20-455217.
ESPP presentation to EU Waste Water Network, 4th June 2024 “EU policies driving nutrient removal and recycling
and the revised UWWTD (Urban Waste Water Treatment Directive)”
The use of Nauplii and metanauplii artemia in aquaculture (brine shrimp).pptxMAGOTI ERNEST
Although Artemia has been known to man for centuries, its use as a food for the culture of larval organisms apparently began only in the 1930s, when several investigators found that it made an excellent food for newly hatched fish larvae (Litvinenko et al., 2023). As aquaculture developed in the 1960s and ‘70s, the use of Artemia also became more widespread, due both to its convenience and to its nutritional value for larval organisms (Arenas-Pardo et al., 2024). The fact that Artemia dormant cysts can be stored for long periods in cans, and then used as an off-the-shelf food requiring only 24 h of incubation makes them the most convenient, least labor-intensive, live food available for aquaculture (Sorgeloos & Roubach, 2021). The nutritional value of Artemia, especially for marine organisms, is not constant, but varies both geographically and temporally. During the last decade, however, both the causes of Artemia nutritional variability and methods to improve poorquality Artemia have been identified (Loufi et al., 2024).
Brine shrimp (Artemia spp.) are used in marine aquaculture worldwide. Annually, more than 2,000 metric tons of dry cysts are used for cultivation of fish, crustacean, and shellfish larva. Brine shrimp are important to aquaculture because newly hatched brine shrimp nauplii (larvae) provide a food source for many fish fry (Mozanzadeh et al., 2021). Culture and harvesting of brine shrimp eggs represents another aspect of the aquaculture industry. Nauplii and metanauplii of Artemia, commonly known as brine shrimp, play a crucial role in aquaculture due to their nutritional value and suitability as live feed for many aquatic species, particularly in larval stages (Sorgeloos & Roubach, 2021).
Phenomics assisted breeding in crop improvementIshaGoswami9
As the population is increasing and will reach about 9 billion upto 2050. Also due to climate change, it is difficult to meet the food requirement of such a large population. Facing the challenges presented by resource shortages, climate
change, and increasing global population, crop yield and quality need to be improved in a sustainable way over the coming decades. Genetic improvement by breeding is the best way to increase crop productivity. With the rapid progression of functional
genomics, an increasing number of crop genomes have been sequenced and dozens of genes influencing key agronomic traits have been identified. However, current genome sequence information has not been adequately exploited for understanding
the complex characteristics of multiple gene, owing to a lack of crop phenotypic data. Efficient, automatic, and accurate technologies and platforms that can capture phenotypic data that can
be linked to genomics information for crop improvement at all growth stages have become as important as genotyping. Thus,
high-throughput phenotyping has become the major bottleneck restricting crop breeding. Plant phenomics has been defined as the high-throughput, accurate acquisition and analysis of multi-dimensional phenotypes
during crop growing stages at the organism level, including the cell, tissue, organ, individual plant, plot, and field levels. With the rapid development of novel sensors, imaging technology,
and analysis methods, numerous infrastructure platforms have been developed for phenotyping.
Current Ms word generated power point presentation covers major details about the micronuclei test. It's significance and assays to conduct it. It is used to detect the micronuclei formation inside the cells of nearly every multicellular organism. It's formation takes place during chromosomal sepration at metaphase.
Or: Beyond linear.
Abstract: Equivariant neural networks are neural networks that incorporate symmetries. The nonlinear activation functions in these networks result in interesting nonlinear equivariant maps between simple representations, and motivate the key player of this talk: piecewise linear representation theory.
Disclaimer: No one is perfect, so please mind that there might be mistakes and typos.
dtubbenhauer@gmail.com
Corrected slides: dtubbenhauer.com/talks.html
ESA/ACT Science Coffee: Diego Blas - Gravitational wave detection with orbita...Advanced-Concepts-Team
Presentation in the Science Coffee of the Advanced Concepts Team of the European Space Agency on the 07.06.2024.
Speaker: Diego Blas (IFAE/ICREA)
Title: Gravitational wave detection with orbital motion of Moon and artificial
Abstract:
In this talk I will describe some recent ideas to find gravitational waves from supermassive black holes or of primordial origin by studying their secular effect on the orbital motion of the Moon or satellites that are laser ranged.
Remote Sensing and Computational, Evolutionary, Supercomputing, and Intellige...University of Maribor
Slides from talk:
Aleš Zamuda: Remote Sensing and Computational, Evolutionary, Supercomputing, and Intelligent Systems.
11th International Conference on Electrical, Electronics and Computer Engineering (IcETRAN), Niš, 3-6 June 2024
Inter-Society Networking Panel GRSS/MTT-S/CIS Panel Session: Promoting Connection and Cooperation
https://www.etran.rs/2024/en/home-english/
The technology uses reclaimed CO₂ as the dyeing medium in a closed loop process. When pressurized, CO₂ becomes supercritical (SC-CO₂). In this state CO₂ has a very high solvent power, allowing the dye to dissolve easily.
When I was asked to give a companion lecture in support of ‘The Philosophy of Science’ (https://shorturl.at/4pUXz) I decided not to walk through the detail of the many methodologies in order of use. Instead, I chose to employ a long standing, and ongoing, scientific development as an exemplar. And so, I chose the ever evolving story of Thermodynamics as a scientific investigation at its best.
Conducted over a period of >200 years, Thermodynamics R&D, and application, benefitted from the highest levels of professionalism, collaboration, and technical thoroughness. New layers of application, methodology, and practice were made possible by the progressive advance of technology. In turn, this has seen measurement and modelling accuracy continually improved at a micro and macro level.
Perhaps most importantly, Thermodynamics rapidly became a primary tool in the advance of applied science/engineering/technology, spanning micro-tech, to aerospace and cosmology. I can think of no better a story to illustrate the breadth of scientific methodologies and applications at their best.
Training load and injuries in football- lessons from research and practise
1. Training load management
in football -
Lessons learned from
research and practice
Torstein Dalen-Lorentsen, PhD
Research Manager SINTEF Digital
Researcher Oslo Sports Trauma Research Center
@torsteindalen
Fotbollmedicinsk konferens SVFF Stockholm 2023
39. Meaning:
South facing traffic light on
corner X/X
turned red
Wisdom
Knowledge
Information
Data
Raw: Red
Context:
The traffic ligth I am
driving towards has
turned red
41. Meaning:
South facing traffic light on
corner X/X
turned red
Wisdom
Knowledge
Information
Data
Raw: Red
Context:
The traffic ligth I am
driving towards has
turned red
Applied:
I’d better stop the car
Raw: 500m
sprinting
Meaning:
Player has sprinted
170% more than
normal
Context:
Player has sprinted
200% of her game
demand
Applied:
Player should train less
than normal tomorrow
47. Feedback
In-session
adjustment
Day-to-day planning
Season planning
Long-term use
Managing an athletes progression from
youth team into the senior team
Identify periods of increased load or stress that may impact
upon injury or performance outcomes
Based on the previous session, should tomorrows
session be harder or easier for some athletes?
Live feedback on player exposure and
response
Did this session meet our desired training targets, relative to the match
demands?
West S et al 2020
48. Find the optimal amount of
training load for each player
…For every
MonthWeekDaySessionDrill
But how?
55. 1 Systematic review of randomised controlled trials (RCT)
or high-quality individual RCT
2 Systematic review of cohort studies
or high-quality individual cohort study and low quality RCT
3 Systematic review of case-control studies
or high-quality individual case-control study
4 Case-series and poor quality cohort and case-control studies
5 Expert opinion
Level of evidence ACWR
(Oxford centre for evidence-based medicine, 2009)
56. 1 Systematic review of randomised controlled trials (RCT)
or high-quality individual RCT
2 Systematic review of cohort studies
or high-quality individual cohort study and low quality RCT
3 Systematic review of case-control studies
or high-quality individual case-control study
4 Case-series and poor quality cohort and case-control studies
5 Expert opinion (n = )
∞
(Oxford centre for evidence-based medicine, 2009)
Level of evidence ACWR
57. 1 Systematic review of randomised controlled trials (RCT)
or high-quality individual RCT
2 Systematic review of cohort studies
or high-quality individual cohort study and low quality RCT
3 Systematic review of case-control studies
or high-quality individual case-control study
4 Case-series and poor quality cohort and case-control studies
5 Expert opinion
(Oxford centre for evidence-based medicine, 2009)
(n = >150)
Level of evidence ACWR
58. Conceptual problems
“As in biology, anatomy dictates physiology.
The anatomy (design) of a study dictates what
it can and cannot do” Grimes & Schultz, 2002
4 Poor quality cohort studies
Impellizzeri et al 2020, Dalen-Lorentsen 2021
Methodological problems
59. Mufano et al 2017
Impellizzeri et al 2020
Dalen-Lorentsen et al 2021
No conceptual
framework
Median n of
Incidents = 72
N of analyses
N of combinations
Biased conclusions
>90 % are
positive findings
Low compliance
Missing data
Six threats to reproducible science
Mufano et al, 2017
60. 1 Systematic review of randomised controlled trials (RCT)
or high-quality individual RCT
2 Systematic review of cohort studies
or high-quality individual cohort study and low quality RCT
3 Systematic review of case-control studies
or high-quality individual case-control study
4 Case-series and poor quality cohort and case-control studies
5 Expert opinion
Level of evidence ACWR
(Oxford centre for evidence-based medicine, 2009)
(n = )
∞
(n = >150)
61. 1 Systematic review of randomised controlled trials (RCT)
or high-quality individual RCT
2 Systematic review of cohort studies
or high-quality individual cohort study and low quality RCT
3 Systematic review of case-control studies
or high-quality individual case-control study
4 Case-series and poor quality cohort and case-control studies
5 Expert opinion
Level of evidence ACWR
(n = 1)
(Oxford centre for evidence-based medicine, 2009)
63. 1 Systematic review of randomised controlled trials (RCT)
or high-quality individual RCT
2 Systematic review of cohort studies
or high-quality individual cohort study and low quality RCT
3 Systematic review of case-control studies
or high-quality individual case-control study
4 Case-series and poor quality cohort and case-control studies
5 Expert opinion
(Oxford centre for evidence-based medicine, 2009)
Status
65. Training load causes health problems
No evidence…. But
Bittencourt et al 2016
sRPE
Total distance
Sprint distance
Accelerations
High intensity actions
Playing style
Previous injury
Age
Muscle strength
Mental state
Fitness
66. Training load causes health problems
Training load management prevents health
problem
79. What load management
should be used for
• Should be used for:
‒ Planning and control of training
Inform training process decisions together
with many other factors
• Can not be used for:
‒ Accurate injury prediction
‒ Holy grail of injury prevention
80. Det är fysioterapeuter och läkare som jobbar med, eller är intresserade av,
fotbollsmedicin. Det är lite mixad kompetens, vissa har jobbat länge inom
elitverksamhet fotboll, andra är nyexaminerade och har intresse mot
idrotts/fotbollsmedicin. Du kan hålla en ’hög nivå’ på presentationen.
Sikta på max 30 min presentation så att vi har tid för diskussion – jag är säker på
att det kommer bli många frågor från auditoriet.
Praktiska erfarenheter och evidens gällande belastningsstyrning i fotboll (vi kan
bolla en exakt titel).
Teknologi for et bedre samfunn
81. • Intro
• How
• Why
• Where to now?
1. Why?
‒ Underlying theory, principles and rationale for load measurement/management
2. How?
‒ Long- and short-term planning
‒ Longitudinal analysis
3. Where to now?
‒ Limitations & discussion
90. Invited
(N=63 teams)
Intervention group (N=11 teams) Control group (N=14 teams)
Full analysis set
N=394
Participants
25
Difference in health problems prevalence and substantial health
problems
Generalised estimating equation
94. 0%
10%
20%
30%
40%
50%
60%
70%
80%
90%
100%
2 3 4 5 6 7 8 9 10
Prevalence
(%)
Month
Control
Intervention
Alle health problems
Control: 64.2% (95% CI 60.4% to 67.7%)
Intervention: 65.8% (95% CI 61.4% to 70.2%)
No effect
Dalen-Lorentsen et al 2021
95. 0%
10%
20%
30%
40%
50%
60%
70%
80%
90%
100%
2 3 4 5 6 7 8 9 10
Prevalence
(%)
Month
Control
Intervention
Substantial health problems
Control: 35.7% (95% CI 32.1% to 39.4%)
Intervention: 31.1% (95% CI 27.4% to 36.1%)
No effect
Dalen-Lorentsen et al 2021
Probably wondering why i chose this picture as the backgroun.d and in addition to being a very nice picture from norway, it is also very relevant to training load management.
I will get back to exacly why towards the end.
But first - lets dive into how we work with training load management
How does injuries, fitness and performance relate to training load
How?
The actual work that is performed
Physiological – locomotive actions, everything related to metabolism
Mechanical – start/stop/cutting action, everything related to ground reaction forces
Internal – response to the external
Raw data into tangible insights we can use
When we have control of these data.
Next step is to include context and turn them into wisdom. This must be done before decision making is performed.
DIKW pyramid
Lets say that a self driving tesla approaching an intersection
What does the car need to know?
Not only on a day to day basis
How?
ACWR as an example. Extremely popular topic and were hyped by major journals and on social media.
From this period, there were two major claims.
Training load causes health problems
And that by changing the training load, you could prevent health problems.
In this talk, I will look at the evidence behind both of these
So what’s the evidence.
When assessing evidence - the level of evidence pyramid is a good way to start
By using this, we find that most articles are actually in the bottom level, often as editorials without any data
There are also a large number of prospective cohort-studies.
But, as our group and many others have pointed out, these have major limitations. These weaknesses can broadly be divided into two groups, conceptual and methodological problems
To quote a brilliant paper from grimes and Shultz. “As in biology, anatomy dictates physiology. The anatomy (design) of a study dictates what it can and cannot do” and as these studies are mostly observational without any conceptual framework , they cannot assess causality.
There is also a lack of both theoretical and conceptual model, which leaves the researcher with endless degrees of freedom in their design and analysis
In a paper called a manif
To summarise, the evidence behind the claim training load causes health problems is more or less non-existing
The only way to examine preventive effect is to use an experimental design. And as there were no RCTs in this field of research, we aimed to test the preventive effect of load management using ACWR, using a cluster randomised design
This is where we are at, a lot of positives from the editorials. Positive associations reported from cohort studies that lack both the methodological quality and the study design for assessing causality, and a negative answer from one RCT.
But it all makes so much sense. Why cant we seem to find a causal link?
As demonstrated by Bittencourt, health problems are a complex and dynamic outcome that is influenced by a multitude of factors.
There is no doubt that training load plays a part in this complex puzzle of factors, but how, and by which magnitude is currently not answered in the litterature
Over to the next claim. Based on the only paper who has investigated this, using a one size fits all approach and ACWR, then NO
One of the reasons migth be the complexity of the training load an health problem relationship
Load small piece of the puzle. MANY contextual factors
In this paper led by Stephen West, we aimed to illustrate the complexity of contextual factors that inform player management
These are grouped into team-level factors. Such as the content of training session or the context of match. Environmental factors like temperature and surface.
And factors on a player-level.
Training load is highlighted in a yellow box to demonstrate it is only a small part of the overall picture.
With all these factors, many of which is not possible to measure, nevermind trying to use them in an RCT, I think its fair to say
So, altogether, with all the individual contextual factors and the balance of risk versus reward, I think its fair to say that training load management still is more an art than a science
There is no exact calculation to know this
Other non-measurable factors
Other non-measurable factors
Remember one thing from this presentation, its this picture.
Training load management can be seen in the same way we build roads up mountains .it might be tempting to go straigth up from the ferry dock at the bottom, but that would be too steep and probably not safe.
In stead, we follow a steady progression all the way to the top. And by going this way, we give the players time to adapt along we go and get everyone with us to the mountain top.
The contextual factors are numerous, but as Martin Buchheit pointed out in this brilliant blog, when making decisions on player management,
content is king, but contex is god So we really need to take them into consideration
Both the intervention group and the control group registered their weekly health problem prevalence once per month, using the oslo sports trauma research center questionnaire on health problems
This questionnaire consist of four questions surrounding participation, training volume, performance and symptoms. Based on the answers, the players were catergorised into three groups, no health problem, health problem and substantial health problems. We calculated the prevalence of both health problems and substantial health problems by dividing the number of players in each of these categories to the total amount of players. So, if you have sixteen players and four of them reports a health problem. The health problem prevalence would be 25% for that week. To investigate the effect of the intervention, we compared the prevalence between the groups
The intervention group also received the intervention that consisted of load management using ACWR
The load management programme was based on this editorial that outlined this figure including the sweet spot concept. Meaning training should be planned to follow an ratio between these thresholds
The players registered their duration and rating of perceived exertion for all footballing activity, which we calculated to a combined session rpe score
This score was then automatically updated in the coaches dashboard in the athlete management system, as we can see here.
The coaches could then use the training load to make a training plan within the thresholds.
If a player were planned to have a higher ACWR than the upper threshold, he was then marked in red, as player 20 here
And a suggestion appeared to the coach to decrease the load accoringly
We invited 63 teams of which 25 agreed to be randomised into the two groups.
When excluding all players who did not respond to any health questionnaires, we ended up with a full analysis set of almost 400 players.
We used a Generalised estimating equations panel data models to analyse the between-group difference in prevalence of health problems and substantial health problems
The players were the best under 19- players of both sexes, with an average age of 17 years
We recorded two and a half thousand health reports which gave us a compliance of 69 %
We received more than 15 000 training session which were 74% of all planned activity
In a post study questionnaire, we asked the coaches if they had used the programme as intended every week of the season, 63 % answered yes and the remaining 30 percent said they had used it less frequently
Over to the main results.
On the Y-axis you will see the health problem prevalence, the proportion of players in each group that reported a health problem at each time point. The solid line is the intervention group and the grey is the control group
As we can see, these lines followed each other quite closely and we concluded that the intervention had no effect
The same for substantial health problems.
Also here, the groups followed each other throughout the season and we observed no effect of the intervention
The main limitation of this study is the lack of an quantitative assessment of compliance to the intervention
Whereas one of the strengths was the broad health problem registration that enabled us to capture overuse injuries, which probably is the most likely health problem group to be prevented by load management