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Management of Arthritis:
Recent Trends
Dr. Neeraj Aggarwal MS, FJRS
Consultant Orthopaedic & Joint Replacement surgeonConsultant Orthopaedic & Joint Replacement surgeon
Narayana Hrudayalaya Hospital
Pratap Nagar, Jaipur.
Objectives of today’s discussion
• Discuss the prevalence of degenerative Knee
Osteoarthritis (OA)
• Understand and discuss different approaches to treat
Knee OA
• Discuss the Indications, Priority and Clinical outcomes
of Knee Replacement
 
                                                                                                                             
• The knee joint is protected
in front by the patella
• Meniscus - acts as a shock
absorber
• Articular cartilage allows
the surfaces of the knee
to glide over each other
without damaging the
surface
Anatomy of Knee
Prevalence of Knee Pain
(Croft et al, 1998)
7,500• Knee pain, some disability & X-ray OA
12,500• Knee pain with some disability
25,000• 4 weeks of knee pain in past year
• Knee pain, severe disability & X-ray OA
2,000
100,000• Subjects aged 55 years+
2%
• About 7 crore Indians are suffering from knee related
problems
• Evidence suggests that women have a higher incidence
of OA than men, and overall have an incidence of 2.95
per 1000 population, compared with 1.71 per 1000
population in men
Prevalence of Knee OA
Why is this problem more prevalent in
India
• Squatting / Ground sitting habits
• Climbing stairs
• Indian Toilets
• Obesity
• Complicated patients
• Heredity
Can we prevent Osteoarthritis
Symptoms
• Pain in and around the Knee joint
• Morning Stiffness (worse on standing &
attempting to walk)
• Swelling of Joint
• Occasional night pain
Characteristics of Knee OA
The symptoms of OA may interfere with normal
activities, such as walking, dressing and sleep
Characteristics of Knee OA
Signs
• Crepitus on motion
• Buckling or instability
• Tenderness on pressure
• Joint effusion
• Malalignment / Joint deformity
REDUCTION IN CARTILAGEREDUCTION IN CARTILAGE
Always ask for weight bearing X-rays
Grade 1
Grade 3
Grade 2
All Grade 4
Treatment Approaches
• Education
• Behavioural and Environmental changes
• Physical and Mechanical Interventions
• Pharmacological Management
• Surgical Interventions
Education
• Education of Patients
– helps in reducing impact of condition on their
day-to-day lives
• Advice about lifestyle
• Impact vs. Non impact activities
WEIGHTWEIGHT
Physical and Mechanical Interventions
• Heat and Cold applications
– to reduce inflammation
• Walking aids
– reduce the loading on the knee while walking
• Shoe alterations
– help the patient get their footwear right
– Knee braces
Physiotherapy
• Physiotherapy aims to restore function to
the maximum degree possible – through
exercises
– helps reduce pain
– increases joint range of movement
– improves muscles strength
– addresses specific restrictions in activities
• Exercises:
- Static Quadriceps Exercises
- Quadriceps Building Exercises
- Hamstring Building Exercises
- Isokinetic Exercises for knee joint
- Progressive resistance Exercises
PRECAUTIONSPRECAUTIONS
• Take rest in between if it is needed
• No squatting on floor
• No cross legged sitting (Alathi – Palathi)
on floor
• Reduce climbing stairs
• Cycling is good
• Swimming Mother of all exercises
Pharmacological Management
• Systemic
 Paracetamol, NSAIDs
 Cox-2 Inhibitors
• Topical
• Intra-articular
 Steroids
 Hyaluronic Acid
My analgesic of choice…
• Paracetamol+Low dose Tramadol
• Synergistic combination
• Block both pathways
• Dose titration (2-8 tab a day)
• GI safety
D.M.A.R.D.
Do we have
D.M.A.OAOA.D.
? ? ?? ? ?
D.M.A.OAOA.D. ? ? ?
Texanamic acid – Anti plasmin activator
CMT – Chemically Modified Tetracyclin
– Inhibit MMP, Nitric oxygenase formation, prevent cartilage wear in animals
Poly sulfated Glucosamino-glycan.
– GOOD animal studies. Limited experiencd in human beings.
– Fear of “mad cow disease “, anaphylaxis
Diacerin
– Again efficacy not established
Glucosamine
– In selected cases
NONE like DMARD yet !NONE like DMARD yet !
Intra-articular
Steroids
• Indicated when knee is inflamed
• Confirm intra-articular placement by draining
effusion, then injection
• Wide variation in responses
Viscosupplementation
• Replaces pathologic
synovial fluid
• Supplements elasticity and
viscosity
• Reduces pain and
improves mobility
How do we know that the
patient needs surgery ?
• Regular pain needing medication
• Deformity of the knee, crepitus in knee
• Night pain, getting up pain
• Altered social or family life due to pain
OSTEO ARTHRITIS
INDICATION – PENALTY POINTS ( 75 PLUS)
Progression + Disability
Pain Deformity ROM Instability
40 20 20
REPLACEMENT SURGERY
20
• FIVE LAKH IS THE NUMBER OF KNEE
REPLACEMENT SURGRIES DONE IN USA IN
2008
• IN INDIA THE CORRESPONDING NUMBER IS
35000 IN 2008
• WITH ALL OUR MANFORCE WE ARE ABLE
TO TACKLE ONLY 3% OF TOTAL ARTHRITIS
PATIENTS
• WHERE ARE WE ???????
Normal kneeNormal knee Arthritic Knee
Total Knee Replacement
• The ultimate solution for OA of knee is to replace the
worn-out parts of the knee with an artificial joint
• The prosthesis that is used is made up of plastic and
metal and is placed on the joint surface of each bone
• This surgery has been widely used for many years with
excellent results especially for knees
Third Generation Knee
How the Artificial knee
fits on the bones ?
Modern Knee
Where to undergo
Surgery…
Post-Op TKR
AP Lateral
Common Post-Operative (TKR) Course
• Day 1 Standing, bending and sitting out in a chair
May take a few steps with help
• Day 2 Walking (with aids)
• Day 4/5 Stair climbing
• Day 5-7 Home (with 2 walking sticks)
• Week 6 Walking unaided (or 1 stick)
Driving
• Week 10-12 Full recovery
Benefits of TKR
• TKR can relieve pain that doesn't respond to other
treatment options
• Pain reduction in 90 to 95% of the patients
• Reduced stiffness and improved joint movement
• Increased walking ability
• Improved alignment of deformed joints
Myths
• Hip replacement works but knee replacement doesn’t
• Knee replacements are still experimental
• Knee replacements only last 8-10 years may be 15 years
maximum
• I am too fat - my implants might break
• TKR surgery is too costly
• TKR is not successful
• After TKR, I have to be bedridden for 3 months
• A total knee replacement implies that everything about the
joint is being replaced
Myths
Question about ?
• Team
• Availability
• Approachability
• Economy
Summary
• Knee OA, which has not responded to conservative treatment
can be effectively treated by various surgical interventions
• Effective grading of patients, counceling and management
serves as a tool to combat osteoarthritis
• Knee replacement surgery is a highly successful
(90-95%) and safe procedure
• Prioritising and effective screening by GPs can identify those
individuals that are likely to benefit from TKR
Future ………
• Robotics
• Custom Implants and Instruments
• Stem cell therapy
Appreciate your attentionAppreciate your attention

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Total hip replacement in jaipur

  • 1. Management of Arthritis: Recent Trends Dr. Neeraj Aggarwal MS, FJRS Consultant Orthopaedic & Joint Replacement surgeonConsultant Orthopaedic & Joint Replacement surgeon Narayana Hrudayalaya Hospital Pratap Nagar, Jaipur.
  • 2. Objectives of today’s discussion • Discuss the prevalence of degenerative Knee Osteoarthritis (OA) • Understand and discuss different approaches to treat Knee OA • Discuss the Indications, Priority and Clinical outcomes of Knee Replacement
  • 3.                                                                                                                                 • The knee joint is protected in front by the patella • Meniscus - acts as a shock absorber • Articular cartilage allows the surfaces of the knee to glide over each other without damaging the surface Anatomy of Knee
  • 4.
  • 5. Prevalence of Knee Pain (Croft et al, 1998) 7,500• Knee pain, some disability & X-ray OA 12,500• Knee pain with some disability 25,000• 4 weeks of knee pain in past year • Knee pain, severe disability & X-ray OA 2,000 100,000• Subjects aged 55 years+ 2%
  • 6. • About 7 crore Indians are suffering from knee related problems • Evidence suggests that women have a higher incidence of OA than men, and overall have an incidence of 2.95 per 1000 population, compared with 1.71 per 1000 population in men Prevalence of Knee OA
  • 7. Why is this problem more prevalent in India • Squatting / Ground sitting habits • Climbing stairs • Indian Toilets • Obesity • Complicated patients • Heredity Can we prevent Osteoarthritis
  • 8. Symptoms • Pain in and around the Knee joint • Morning Stiffness (worse on standing & attempting to walk) • Swelling of Joint • Occasional night pain Characteristics of Knee OA The symptoms of OA may interfere with normal activities, such as walking, dressing and sleep
  • 9. Characteristics of Knee OA Signs • Crepitus on motion • Buckling or instability • Tenderness on pressure • Joint effusion • Malalignment / Joint deformity
  • 11. Always ask for weight bearing X-rays Grade 1 Grade 3 Grade 2 All Grade 4
  • 12. Treatment Approaches • Education • Behavioural and Environmental changes • Physical and Mechanical Interventions • Pharmacological Management • Surgical Interventions
  • 13. Education • Education of Patients – helps in reducing impact of condition on their day-to-day lives • Advice about lifestyle • Impact vs. Non impact activities
  • 15. Physical and Mechanical Interventions • Heat and Cold applications – to reduce inflammation • Walking aids – reduce the loading on the knee while walking • Shoe alterations – help the patient get their footwear right – Knee braces
  • 16. Physiotherapy • Physiotherapy aims to restore function to the maximum degree possible – through exercises – helps reduce pain – increases joint range of movement – improves muscles strength – addresses specific restrictions in activities • Exercises: - Static Quadriceps Exercises - Quadriceps Building Exercises - Hamstring Building Exercises - Isokinetic Exercises for knee joint - Progressive resistance Exercises
  • 17. PRECAUTIONSPRECAUTIONS • Take rest in between if it is needed • No squatting on floor • No cross legged sitting (Alathi – Palathi) on floor • Reduce climbing stairs • Cycling is good • Swimming Mother of all exercises
  • 18. Pharmacological Management • Systemic  Paracetamol, NSAIDs  Cox-2 Inhibitors • Topical • Intra-articular  Steroids  Hyaluronic Acid
  • 19. My analgesic of choice… • Paracetamol+Low dose Tramadol • Synergistic combination • Block both pathways • Dose titration (2-8 tab a day) • GI safety
  • 21. D.M.A.OAOA.D. ? ? ? Texanamic acid – Anti plasmin activator CMT – Chemically Modified Tetracyclin – Inhibit MMP, Nitric oxygenase formation, prevent cartilage wear in animals Poly sulfated Glucosamino-glycan. – GOOD animal studies. Limited experiencd in human beings. – Fear of “mad cow disease “, anaphylaxis Diacerin – Again efficacy not established Glucosamine – In selected cases NONE like DMARD yet !NONE like DMARD yet !
  • 22. Intra-articular Steroids • Indicated when knee is inflamed • Confirm intra-articular placement by draining effusion, then injection • Wide variation in responses
  • 23. Viscosupplementation • Replaces pathologic synovial fluid • Supplements elasticity and viscosity • Reduces pain and improves mobility
  • 24. How do we know that the patient needs surgery ? • Regular pain needing medication • Deformity of the knee, crepitus in knee • Night pain, getting up pain • Altered social or family life due to pain
  • 25. OSTEO ARTHRITIS INDICATION – PENALTY POINTS ( 75 PLUS) Progression + Disability Pain Deformity ROM Instability 40 20 20 REPLACEMENT SURGERY 20
  • 26. • FIVE LAKH IS THE NUMBER OF KNEE REPLACEMENT SURGRIES DONE IN USA IN 2008 • IN INDIA THE CORRESPONDING NUMBER IS 35000 IN 2008 • WITH ALL OUR MANFORCE WE ARE ABLE TO TACKLE ONLY 3% OF TOTAL ARTHRITIS PATIENTS • WHERE ARE WE ???????
  • 27. Normal kneeNormal knee Arthritic Knee
  • 28.
  • 29. Total Knee Replacement • The ultimate solution for OA of knee is to replace the worn-out parts of the knee with an artificial joint • The prosthesis that is used is made up of plastic and metal and is placed on the joint surface of each bone • This surgery has been widely used for many years with excellent results especially for knees
  • 30. Third Generation Knee How the Artificial knee fits on the bones ?
  • 32.
  • 33.
  • 34.
  • 35.
  • 36.
  • 37.
  • 40. Common Post-Operative (TKR) Course • Day 1 Standing, bending and sitting out in a chair May take a few steps with help • Day 2 Walking (with aids) • Day 4/5 Stair climbing • Day 5-7 Home (with 2 walking sticks) • Week 6 Walking unaided (or 1 stick) Driving • Week 10-12 Full recovery
  • 41. Benefits of TKR • TKR can relieve pain that doesn't respond to other treatment options • Pain reduction in 90 to 95% of the patients • Reduced stiffness and improved joint movement • Increased walking ability • Improved alignment of deformed joints
  • 42. Myths • Hip replacement works but knee replacement doesn’t • Knee replacements are still experimental • Knee replacements only last 8-10 years may be 15 years maximum • I am too fat - my implants might break
  • 43. • TKR surgery is too costly • TKR is not successful • After TKR, I have to be bedridden for 3 months • A total knee replacement implies that everything about the joint is being replaced Myths
  • 44. Question about ? • Team • Availability • Approachability • Economy
  • 45. Summary • Knee OA, which has not responded to conservative treatment can be effectively treated by various surgical interventions • Effective grading of patients, counceling and management serves as a tool to combat osteoarthritis • Knee replacement surgery is a highly successful (90-95%) and safe procedure • Prioritising and effective screening by GPs can identify those individuals that are likely to benefit from TKR
  • 46. Future ……… • Robotics • Custom Implants and Instruments • Stem cell therapy Appreciate your attentionAppreciate your attention

Editor's Notes

  1. Slide 35 Synovial fluid in the pathologic joint does not have the same elastic and viscous properties as SF of the healthy joint. Therefore, the lubricating and shock absorbing effects of hyaluronan in the joint space and intercellular matrix are diminished.1 Current OA treatment focuses on decreasing pain with analgesics and anti-inflammatory drugs. Viscosupplementation improves the physiological environment in the osteoarthritic joint by reestablishing shock absorption and lubrication to the cartilage and soft tissues that it bathes and permeates. Thus, it directly addresses the tissues that are the source of the OA pain.1,2 Viscosupplementation improves the elastoviscous environment of the collagen fibrous network, the cells, and the nociceptors.1 1Balazs EA, Denlinger JL. Viscosupplementation: a new concept in the treatment of osteoarthritis. J Rheumatol. 1993;20(suppl 39):3-9. 2Wobig M, Dickhut A, Maier R, Vetter G. Viscosupplementation with Hylan G-F 20: a 26-week controlled trial of efficacy and safety in the osteoarthritic knee. Clin Ther. 1998;20:410-423.