This document discusses inconvenient truths and consequences that universities may face in the next 20 years due to global changes. It notes that economic globalization has exposed vulnerabilities in the global market economy and potentially capitalism. Issues like climate change, growth in China and India, wars, hunger for resources, and reliance on fossil fuels will impact society in coming decades. The document argues that the US in particular has been slow to address issues like climate change and may face penalties for devaluing higher education. It suggests many aspects of science, engineering, and technology will need to change in response to global shifts.