This document describes a field trial comparing the efficacy of THYMOX Technology footbaths containing 1% THYMOX versus copper sulfate (CuSO4) footbaths containing 5% CuSO4 in controlling digital dermatitis (DD) in dairy cow herds. Over 650 cows on multiple dairy farms were observed and scored for hoof lesions over 12 weeks while exposed to the two different footbath treatments. The results of the field trial showed that THYMOX footbaths were predicted to result in the same or lower levels of chronic DD lesions and the same or higher levels of healthy hooves compared to CuSO4 footbaths.