This document is a 96-page MSc dissertation that explores adapting Quality by Design (QbD) principles to the development of biomedical technologies. It presents efforts to implement QbD in developing an assistive robotic device for elderly locomotion. It establishes the device's Target Product Profile through a questionnaire given to elderly care experts. Using this and literature, it identifies critical quality attributes and critical process parameters for the device. As conventional QbD statistical methods are not feasible, it configures the device's design space through an adaptation of fuzzy logic modeling.