This document provides tips for building a healthy relationship. It discusses maintaining an emotional connection with your partner where each person feels loved and accepted. Healthy relationships also involve not fearing respectful disagreements and being able to resolve conflicts constructively. Additionally, maintaining outside relationships and individual interests is important to prevent unhealthy pressure and stimulate personal growth within the relationship. The document encourages learning more relationship tips to attract a partner.
Want to feel loved and connected to your partner? These tips can help you build
and keep a romantic relationship that’s healthy, happy, and satisfying.
In the United States, nearly 1 million marriages end in divorce each year.
The sad part is, many of those divorces are preventable with the right intervention. Yet, it’s a fallacy to believe all marriages can be saved.
There is however, a much better chance of saving your marriage if you assess your relationship and understand the root cause of your marriage problems.
If your marriage is in trouble, the worst thing you can do is to over analyze the situation.
Love is a feeling felt by everyone! But most times this feeling could either be misunderstood or not reciprocated in the right way. This document focuses on everything that has always been a hassle in relationships, tackling it and giving the right advice in order to grow a mature and loving relationship. It helps to grow your relationship with your loved one especially one which has already been battered with lies, lack of trust , disloyalty , loss of feelings , love etc.
How to Keep Your Relationship Warm: A Comprehensive GuideJIbodje
As we navigate through lifestyles, our relationships play a vital function in our happiness and usual well-being. A warm, supportive, and wholesome relationship can convey terrific joy and achievement. However, retaining the warm temperature in a relationship requires constant effort, open verbal exchange, and mutual knowledge. In this comprehensive guide, we are able to discover numerous strategies and recommendations to preserve your courting heat and thriving.
Want to feel loved and connected to your partner? These tips can help you build
and keep a romantic relationship that’s healthy, happy, and satisfying.
In the United States, nearly 1 million marriages end in divorce each year.
The sad part is, many of those divorces are preventable with the right intervention. Yet, it’s a fallacy to believe all marriages can be saved.
There is however, a much better chance of saving your marriage if you assess your relationship and understand the root cause of your marriage problems.
If your marriage is in trouble, the worst thing you can do is to over analyze the situation.
Love is a feeling felt by everyone! But most times this feeling could either be misunderstood or not reciprocated in the right way. This document focuses on everything that has always been a hassle in relationships, tackling it and giving the right advice in order to grow a mature and loving relationship. It helps to grow your relationship with your loved one especially one which has already been battered with lies, lack of trust , disloyalty , loss of feelings , love etc.
How to Keep Your Relationship Warm: A Comprehensive GuideJIbodje
As we navigate through lifestyles, our relationships play a vital function in our happiness and usual well-being. A warm, supportive, and wholesome relationship can convey terrific joy and achievement. However, retaining the warm temperature in a relationship requires constant effort, open verbal exchange, and mutual knowledge. In this comprehensive guide, we are able to discover numerous strategies and recommendations to preserve your courting heat and thriving.
7 Signs Your Relationship Is Giving You Anxiety | Solh Wellness.pdfSolh Wellness
Every relationship experiences its fair share of difficulties, disputes, and agreements. Extremely tense relationships, however, are unhealthy. Solh Wellness explains it's signs and what you can do about it.
Through downloading this report, you are taking the first step in beginning to move out of relationship pain. I know it‟s not easy for some people to reach out for support or help, so if that seems like you, know that you are taking a pro-active attitude towards creating the type of relationship you want.
Mario Che's passion is to help people unlock their full potential and live their best life. He firmly believes anyone can achieve greatness with the right mindset, tools, and guidance.
Friendships, on the other hand, tend to be more informal and may involve shared interests, activities, or experiences. They can be based on mutual understanding, trust, and support.
Professional relationships are built on a shared purpose, such as working on a project or toward a common goal. They involve mutual respect, communication and teamwork.
Family relationships, in contrast, are often characterised by a strong sense of loyalty and connection. They can be complex, with dynamics that are shaped by factors such as upbringing, culture, and personal history.
In all types of relationships, it is essential to have open communication, mutual respect, trust, and understanding. It is also important to be willing to compromise, to work through conflicts, and to support each other through the ups and downs of life.
"Navigating Relationship Challenges in Midlife: Strategies for Achieving and...SantoshDas83
Our relationship book is the best idea for all genders as it offers a comprehensive and inclusive approach to building and maintaining healthy relationships. It provides valuable insights and practical advice on how to improve communication, build trust, and navigate the challenges that may arise in any kind of relationship. The book is written with a gender-neutral perspective, making it applicable to people of all genders. It addresses the unique concerns and experiences of different genders and sexual orientations, while providing a common ground of advice and understanding. It covers a range of topics such as setting boundaries, dealing with jealousy, building intimacy, and managing conflicts. Furthermore, it also aims to empower readers to take control of their relationships and create healthier, more fulfilling connections with others. Overall, our relationship book is a comprehensive and inclusive resource that can benefit people of all genders who want to improve their understanding of themselves and their relationships.
7 Ways to Improve your Relationship | Solh Wellness.pdfSolh Wellness
Strengthen your relationship with these practical tips suggested by Solh Wellness, including communication, being a good listener and more. Start building a healthier connection today!
10 Relational Tips_ Nurturing Healthy and Lasting Connections (1).pdfLilian Wachia
In this fast-paced world, maintaining healthy and fulfilling relationships is more important than ever. Whether it's with our partners, family, friends, or colleagues, strong relationships provide support, happiness, and a sense of belonging. In this blog post, we will explore ten practical relational tips that can help you foster and strengthen connections with the people in your life. So, let's dive in and discover how to build long-lasting, fulfilling relationships.
These book will teach you all you need to know to master the art of love, it's different from whatever relationship guides or books you have read before.
So much has been deposited into the creation of these book to help you have a good relationship with your spouse. Also if you are single, I must say you should count yourself Lucky by reading these book. Because you will learn a lot of do's and don't you shouldn't do in your relationship and how to love.
Would you like to enhance the quality of your life and increase your personal happiness? If you answered
"yes," the information in this article could change your life!
Isn't it easy to get stuck in the everydayness of life?
We can get so busy making a living and getting ahead
financially that the really important things fall through the cracks!
That can happen to all of us. However, when people come to the end of their lives, they don't wish they had
spent more time making money.
When all is said and done, we want our family and friends to be with us
then!
So let's try to focus on developing better relationships instead of acquiring more things.
Think of your circle
of family and friends as a lovely garden to water and cultivate.
The book of Proverbs teaches this crucial
truth: "A man that has friends must show himself friendly" (Proverbs 18:24).
Complete Guide on expectations in a relationship for couples!.pdfhttps://akreviews.in/
What are expectations in a relationship?
Some people think it’s best not to expect anything from your partner, but expectations may help you cultivate healthy relationships. If you want to form a well-rounded partnership, you may want to balance high expectations with unreasonable expectations. Expectations may look like rules to make sure partners are contributing to the relationship.
The expectations in a relationship. We can set a baseline for treatment. It’s nice to expect our partners to support us and love us. Our partner doesn’t have to be a mind reader. It's hard to manage expectations. You don’t know what’s asking too much and what’s not enough. A couple with love, care, affection, and loyalty but don’t expect a sun-filled relationship with no conflict is what a couple should expect. It is important that you don’t expect your partner to be everything to you.
There is one thing for certain relationships, and that is discussing expectations. Similar to all parts of a relationship, we must discuss expectations. Discuss what you expect from the other person, and what expectations you have for one another, with your partner, and then review these regularly. Bad things will happen if you think you are going to fail. If you want to be successful, decide what you expect, set them and try to be reasonable.
You cannot expect your partner to change who he or she is. This is a very common problem in relationships. It’s important to set up expectations in several areas before the fear of not being met overwhelms the relationship. Communication is important in a loving relationship.
Different expectations for different things.
In a relationship, each partner brings something valuable to the table, and each contributes uniquely that benefits the relationship. It might not be as clear-cut as you think. Some of you might have different expectations for this new relationship. What are your expectations for the future? A healthy relationship can be created by being realistic about our expectations and being open about any challenges we face.
Communicate your expectations in a relationship.
When we have been together for many years, it’s not realistic to think our partner knows everything. As an individual, think about how you have changed over time, as well as how you might change in the future. Consider the history of the relationship and how expectations may change with transitions. Communication around expectations is important during transitions, such as becoming engaged, married, having children, and even during large moves and career changes. It is possible to maintain a sense of stability when there are clear expectations.
Lack of communication about expectations may lead to disconnection in which one partner may feel too much is being demanded of them, or that their partner is not present and supportive of them.
Developing strong Interpersonal Relationships in Young Adolescent is one of the vital fact that determines teenager's quality of life. The relationship teenagers have with their parents is of utmost importance as it influences all areas of social development. So how these skills can be developed and why these skills are important, these are the areas that Psychologist & Marriage Counselor Shivani Misri Sadhoo has shared in the study.
Healthy relationship is a broad term and it varies according to people's relationship needs, age, cultural perspectives. The important thing is how open communication is and the way two people treat each other does not involve any form of violence . In a healthy relationship model, partners support each other emotionally and respect each other's decisions, independence and lives.
Revive Your Relationship - Ultimate GuideJibranAzhar
Your Love Life has become a scourge in your life and there seems no way to reverse this.
Before time runs out revive your relationship with our timeless book on getting back your relationship on track, tested and approved by over millions of couples.
When it comes to building a successful relationship, it's all about finding the right partner who shares your values and beliefs. It's important to have similar goals and aspirations for the future, and to be able to rely on each other through thick and thin.
Trust and mutual respect are essential for any relationship to thrive. And it's important to remember that love is not about possession, but about connection and growth. By being supportive and understanding, you'll be able to build a strong, long-lasting relationship.
Dating can be a thrilling and exciting experience, but it can also be challenging and difficult. Finding the right person to share your life with requires patience, understanding, and communication. One of the keys to a successful relationship is to build trust and honesty with your partner.
It's also important to remember that love takes time to grow and that it's okay to make mistakes. By being open and honest with yourself and your partner, you'll be able to navigate the ups and downs of dating and build a strong, lasting relationship.
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
7 Signs Your Relationship Is Giving You Anxiety | Solh Wellness.pdfSolh Wellness
Every relationship experiences its fair share of difficulties, disputes, and agreements. Extremely tense relationships, however, are unhealthy. Solh Wellness explains it's signs and what you can do about it.
Through downloading this report, you are taking the first step in beginning to move out of relationship pain. I know it‟s not easy for some people to reach out for support or help, so if that seems like you, know that you are taking a pro-active attitude towards creating the type of relationship you want.
Mario Che's passion is to help people unlock their full potential and live their best life. He firmly believes anyone can achieve greatness with the right mindset, tools, and guidance.
Friendships, on the other hand, tend to be more informal and may involve shared interests, activities, or experiences. They can be based on mutual understanding, trust, and support.
Professional relationships are built on a shared purpose, such as working on a project or toward a common goal. They involve mutual respect, communication and teamwork.
Family relationships, in contrast, are often characterised by a strong sense of loyalty and connection. They can be complex, with dynamics that are shaped by factors such as upbringing, culture, and personal history.
In all types of relationships, it is essential to have open communication, mutual respect, trust, and understanding. It is also important to be willing to compromise, to work through conflicts, and to support each other through the ups and downs of life.
"Navigating Relationship Challenges in Midlife: Strategies for Achieving and...SantoshDas83
Our relationship book is the best idea for all genders as it offers a comprehensive and inclusive approach to building and maintaining healthy relationships. It provides valuable insights and practical advice on how to improve communication, build trust, and navigate the challenges that may arise in any kind of relationship. The book is written with a gender-neutral perspective, making it applicable to people of all genders. It addresses the unique concerns and experiences of different genders and sexual orientations, while providing a common ground of advice and understanding. It covers a range of topics such as setting boundaries, dealing with jealousy, building intimacy, and managing conflicts. Furthermore, it also aims to empower readers to take control of their relationships and create healthier, more fulfilling connections with others. Overall, our relationship book is a comprehensive and inclusive resource that can benefit people of all genders who want to improve their understanding of themselves and their relationships.
7 Ways to Improve your Relationship | Solh Wellness.pdfSolh Wellness
Strengthen your relationship with these practical tips suggested by Solh Wellness, including communication, being a good listener and more. Start building a healthier connection today!
10 Relational Tips_ Nurturing Healthy and Lasting Connections (1).pdfLilian Wachia
In this fast-paced world, maintaining healthy and fulfilling relationships is more important than ever. Whether it's with our partners, family, friends, or colleagues, strong relationships provide support, happiness, and a sense of belonging. In this blog post, we will explore ten practical relational tips that can help you foster and strengthen connections with the people in your life. So, let's dive in and discover how to build long-lasting, fulfilling relationships.
These book will teach you all you need to know to master the art of love, it's different from whatever relationship guides or books you have read before.
So much has been deposited into the creation of these book to help you have a good relationship with your spouse. Also if you are single, I must say you should count yourself Lucky by reading these book. Because you will learn a lot of do's and don't you shouldn't do in your relationship and how to love.
Would you like to enhance the quality of your life and increase your personal happiness? If you answered
"yes," the information in this article could change your life!
Isn't it easy to get stuck in the everydayness of life?
We can get so busy making a living and getting ahead
financially that the really important things fall through the cracks!
That can happen to all of us. However, when people come to the end of their lives, they don't wish they had
spent more time making money.
When all is said and done, we want our family and friends to be with us
then!
So let's try to focus on developing better relationships instead of acquiring more things.
Think of your circle
of family and friends as a lovely garden to water and cultivate.
The book of Proverbs teaches this crucial
truth: "A man that has friends must show himself friendly" (Proverbs 18:24).
Complete Guide on expectations in a relationship for couples!.pdfhttps://akreviews.in/
What are expectations in a relationship?
Some people think it’s best not to expect anything from your partner, but expectations may help you cultivate healthy relationships. If you want to form a well-rounded partnership, you may want to balance high expectations with unreasonable expectations. Expectations may look like rules to make sure partners are contributing to the relationship.
The expectations in a relationship. We can set a baseline for treatment. It’s nice to expect our partners to support us and love us. Our partner doesn’t have to be a mind reader. It's hard to manage expectations. You don’t know what’s asking too much and what’s not enough. A couple with love, care, affection, and loyalty but don’t expect a sun-filled relationship with no conflict is what a couple should expect. It is important that you don’t expect your partner to be everything to you.
There is one thing for certain relationships, and that is discussing expectations. Similar to all parts of a relationship, we must discuss expectations. Discuss what you expect from the other person, and what expectations you have for one another, with your partner, and then review these regularly. Bad things will happen if you think you are going to fail. If you want to be successful, decide what you expect, set them and try to be reasonable.
You cannot expect your partner to change who he or she is. This is a very common problem in relationships. It’s important to set up expectations in several areas before the fear of not being met overwhelms the relationship. Communication is important in a loving relationship.
Different expectations for different things.
In a relationship, each partner brings something valuable to the table, and each contributes uniquely that benefits the relationship. It might not be as clear-cut as you think. Some of you might have different expectations for this new relationship. What are your expectations for the future? A healthy relationship can be created by being realistic about our expectations and being open about any challenges we face.
Communicate your expectations in a relationship.
When we have been together for many years, it’s not realistic to think our partner knows everything. As an individual, think about how you have changed over time, as well as how you might change in the future. Consider the history of the relationship and how expectations may change with transitions. Communication around expectations is important during transitions, such as becoming engaged, married, having children, and even during large moves and career changes. It is possible to maintain a sense of stability when there are clear expectations.
Lack of communication about expectations may lead to disconnection in which one partner may feel too much is being demanded of them, or that their partner is not present and supportive of them.
Developing strong Interpersonal Relationships in Young Adolescent is one of the vital fact that determines teenager's quality of life. The relationship teenagers have with their parents is of utmost importance as it influences all areas of social development. So how these skills can be developed and why these skills are important, these are the areas that Psychologist & Marriage Counselor Shivani Misri Sadhoo has shared in the study.
Healthy relationship is a broad term and it varies according to people's relationship needs, age, cultural perspectives. The important thing is how open communication is and the way two people treat each other does not involve any form of violence . In a healthy relationship model, partners support each other emotionally and respect each other's decisions, independence and lives.
Revive Your Relationship - Ultimate GuideJibranAzhar
Your Love Life has become a scourge in your life and there seems no way to reverse this.
Before time runs out revive your relationship with our timeless book on getting back your relationship on track, tested and approved by over millions of couples.
When it comes to building a successful relationship, it's all about finding the right partner who shares your values and beliefs. It's important to have similar goals and aspirations for the future, and to be able to rely on each other through thick and thin.
Trust and mutual respect are essential for any relationship to thrive. And it's important to remember that love is not about possession, but about connection and growth. By being supportive and understanding, you'll be able to build a strong, long-lasting relationship.
Dating can be a thrilling and exciting experience, but it can also be challenging and difficult. Finding the right person to share your life with requires patience, understanding, and communication. One of the keys to a successful relationship is to build trust and honesty with your partner.
It's also important to remember that love takes time to grow and that it's okay to make mistakes. By being open and honest with yourself and your partner, you'll be able to navigate the ups and downs of dating and build a strong, lasting relationship.
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
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Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
263778731218 Abortion Clinic /Pills In Harare ,sisternakatoto
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New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
The Ultimate List of Women Relationship Tips Do's and Don'ts
1.
2. The Ultimate List of Women Relationship Tips Do's and
Don'ts
Tips for Building a healthy relationship
Building a healthy relationship all romantic relationships go through ups
and downs and they all take work, commitment, and a willingness to adapt
and change with your partner. But whether your relationship is just starting
out or you’ve been together for years, there are steps you can take to build a
healthy relationship. Even if you’ve experienced a lot of failed relationships
in the past or have struggled before to rekindle the fires of romance in your
current relationship, you can find ways to stay connected, find fulfillment,
and enjoy lasting happiness.
3. What makes a healthy relationship?
Every relationship is unique, and people come together for many different
reasons. Part of what defines a healthy relationship is sharing a common
goal for exactly what you want the relationship to be and where you want it
to go. And that’s something you’ll only know by talking deeply and honestly
with your partner.
4. However, there are also some characteristics that most healthy
relationships have in common. Knowing these basic principles can help
keep your relationship meaningful, fulfilling and exciting whatever goals
you’re working towards or challenges you’re facing together.
You maintain a meaningful emotional connection with each other. You each
make the other feel loved and emotionally fulfilled. There’s a difference
between being loved and feeling loved. When you feel loved, it makes you
feel accepted and valued by your partner, like someone truly gets you. Some
relationships get stuck in peaceful coexistence, but without the partners
truly relating to each other emotionally. While the union may seem stable on
the surface, a lack of ongoing involvement and emotional connection serves
only to add distance between two people.
5. You’re not afraid of (respectful) disagreement. Some couples talk things out
quietly, while others may raise their voices and passionately disagree. The
key in a strong relationship, though, is not to be fearful of conflict. You need
to feel safe to express things that bother you without fear of retaliation, and
be able to resolve conflict without humiliation, degradation, or insisting on
being right.
6. You keep outside relationships and interests alive.Despite the claims of
romantic fiction or movies, no one person can meet all of your needs. In
fact, expecting too much from your partner can put unhealthy pressure on a
relationship. To stimulate and enrich your romantic relationship, it’s
important to sustain your own identity outside of the relationship, preserve
connections with family and friends, and maintain your hobbies and
interests.
7. IN Conclusion
I hope enjoyed the learning tips!
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