This meta-analysis was performed to increase knowledge and understanding on prosthetics and to research what works better for these amputees. This should be used to inform us as clinicians as to what we need to focus on with our amputee patients and what to not overlook throughout the rehabilitation process.
Correlation between conventional clinical tests and a new movement assessment...Stavros Litsos
Correlation between conventional clinical tests and a new movement assessment battery - Bachelor thesis
Despite the complexity of movements performed in sports, physical examination is today done by conventional tests that evaluate joints and muscles individually (e.g. Smith press test, Figure1). Our study used a new movement assessment battery of 20 reach tests, which incorporates the complexity and diversity of natural human movements, taking into consideration that joints are interdependent in a movement and that the planes and sequences of a movement change during its performance. The purpose of this study was to determine whether or not there is a correlation between conventional mobility tests and the new assessment battery.
This meta-analysis was performed to increase knowledge and understanding on prosthetics and to research what works better for these amputees. This should be used to inform us as clinicians as to what we need to focus on with our amputee patients and what to not overlook throughout the rehabilitation process.
Correlation between conventional clinical tests and a new movement assessment...Stavros Litsos
Correlation between conventional clinical tests and a new movement assessment battery - Bachelor thesis
Despite the complexity of movements performed in sports, physical examination is today done by conventional tests that evaluate joints and muscles individually (e.g. Smith press test, Figure1). Our study used a new movement assessment battery of 20 reach tests, which incorporates the complexity and diversity of natural human movements, taking into consideration that joints are interdependent in a movement and that the planes and sequences of a movement change during its performance. The purpose of this study was to determine whether or not there is a correlation between conventional mobility tests and the new assessment battery.
Colorado shoulder surgeon, Dr. Peter Millett taught in Portland, Oregon on the Steelhead Surgical Advanced Shoulder Course. Here is a sneak peek of his presentation.
Corrigendum to “Special surgical technique for knee arthroplasty”Apollo Hospitals
We typically operate more than 1200-1800 cases a year, out of which we have included 300 cases randomly for the study. All these selected cases were local residents and easy to follow-up.
A criteria based progression rehabilitation protocol for hamstring strain injuries presented at the Sports Medicine Australia conference 2015 during the Hamstring symposium
Dr. Nikhil Verma is a sports medicine specialist and orthopedic surgeon at Midwest Orthopaedics at Rush located in the greater Chicago, Westchester, Oakbrook and Hindsdale, Illinois area, as well as Director of Sports Medicine Research for the Department of Orthopedic Surgery at Rush University Medical Center. Dr. Verma specializes in disorders of the shoulder, knee and elbow in addition to all sports related injuries. Using both arthroscopic and open surgery to restore joint function, he offers advanced arthroscopic reconstructive techniques and cartilage restoration expertise for patients at all athletic levels.
Dr. Verma is actively involved in orthopedic research with interests in advanced arthroscopic reconstructive techniques and cartilage restoration, basic science, biomechanics and clinical outcomes, and has recently received funding for his work from Major League Baseball (MLB). He has authored multiple peer-reviewed manuscripts in major orthopedic and sports medicine journals, numerous book chapters and routinely serves as teaching faculty for orthopedic courses on advanced surgical technique.
A graduate of the University Of Pennsylvania School Of Medicine, Dr. Verma completed his orthopedic residency at Rush-Presbyterian-St. Luke’s Medical Center. He then completed a fellowship at the Hospital for Special Surgery in sports medicine and shoulder surgery. While in New York, he served as an assistant team physician for the St. John’s University Athletic Department.
Dr. Nikhil Verma, orthopedic surgeon and sports medicine specialist, serves as Professor and Director of Sports Medicine Research for the Department of Orthopedic Surgery at Rush University Medical Center, Associate Editor of the Arthroscopy Journal and on the editorial board of the Journal of Knee Surgery. He is a member of the American Orthopaedic Society for Sports Medicine, American Shoulder and Elbow Society, Arthroscopy Association of North America, Major League Baseball Team Physician Association and is a Fellow in the American Academy of Orthopaedic Surgeons. He has been elected by his peers to "Best Doctors in America" every year since 2007.
For more resources on advanced arthroscopic reconstructive techniques and cartilage restoration, or for additional information on shoulder, knee and elbow sports injuries, please contact the Chicago, Westchester, Oakbrook and Hindsdale, Illinois area office of Dr. Nikhil Verma, sports medicine specialist and orthopedic surgeon.
Colorado shoulder surgeon, Dr. Peter Millett taught in Portland, Oregon on the Steelhead Surgical Advanced Shoulder Course. Here is a sneak peek of his presentation.
Corrigendum to “Special surgical technique for knee arthroplasty”Apollo Hospitals
We typically operate more than 1200-1800 cases a year, out of which we have included 300 cases randomly for the study. All these selected cases were local residents and easy to follow-up.
A criteria based progression rehabilitation protocol for hamstring strain injuries presented at the Sports Medicine Australia conference 2015 during the Hamstring symposium
Dr. Nikhil Verma is a sports medicine specialist and orthopedic surgeon at Midwest Orthopaedics at Rush located in the greater Chicago, Westchester, Oakbrook and Hindsdale, Illinois area, as well as Director of Sports Medicine Research for the Department of Orthopedic Surgery at Rush University Medical Center. Dr. Verma specializes in disorders of the shoulder, knee and elbow in addition to all sports related injuries. Using both arthroscopic and open surgery to restore joint function, he offers advanced arthroscopic reconstructive techniques and cartilage restoration expertise for patients at all athletic levels.
Dr. Verma is actively involved in orthopedic research with interests in advanced arthroscopic reconstructive techniques and cartilage restoration, basic science, biomechanics and clinical outcomes, and has recently received funding for his work from Major League Baseball (MLB). He has authored multiple peer-reviewed manuscripts in major orthopedic and sports medicine journals, numerous book chapters and routinely serves as teaching faculty for orthopedic courses on advanced surgical technique.
A graduate of the University Of Pennsylvania School Of Medicine, Dr. Verma completed his orthopedic residency at Rush-Presbyterian-St. Luke’s Medical Center. He then completed a fellowship at the Hospital for Special Surgery in sports medicine and shoulder surgery. While in New York, he served as an assistant team physician for the St. John’s University Athletic Department.
Dr. Nikhil Verma, orthopedic surgeon and sports medicine specialist, serves as Professor and Director of Sports Medicine Research for the Department of Orthopedic Surgery at Rush University Medical Center, Associate Editor of the Arthroscopy Journal and on the editorial board of the Journal of Knee Surgery. He is a member of the American Orthopaedic Society for Sports Medicine, American Shoulder and Elbow Society, Arthroscopy Association of North America, Major League Baseball Team Physician Association and is a Fellow in the American Academy of Orthopaedic Surgeons. He has been elected by his peers to "Best Doctors in America" every year since 2007.
For more resources on advanced arthroscopic reconstructive techniques and cartilage restoration, or for additional information on shoulder, knee and elbow sports injuries, please contact the Chicago, Westchester, Oakbrook and Hindsdale, Illinois area office of Dr. Nikhil Verma, sports medicine specialist and orthopedic surgeon.
esta presentación resultan de mucha ayuda les ayudara en su vida animo. son algunas ideas extraidas del libro el pajaro herido, y seguido por algunos pensamientos míos espero les sea de ayuda.
Termo dereferencia de area para industria farmaceutica com central de distrib...Jamildo Melo
Sem alarde, o Estado de Pernambuco, através da estatal Suape, estará vendendo um terreno por cerca de 20 milhões de reais.
A concorrência irá se realizar em 17 de fevereiro, sendo que a alienação está condicionada ao comprador instalar no terreno uma indústria farmacêutica ou um centro de distribuição.
Jitterbit Data Loader vs Jitterbit Harmony Cloud ComparisonJitterbit
Need to connect Salesforce data with other systems? Find out whether Jitterbit Data Loader or Jitterbit Harmony will meet your integration needs better.
Quantitative Analysis of Patellar Tendon Abnormality in Asymptomatic Professi...Medical_Lab
Abnormalities in B-mode ultrasound images of the patellar tendon often take place in asymptomatic athletes but it is still not clear if these modifications forego or can predict the development of tendinopathy. Subclinical tendinopathy can be arbitrarily defined as either the presence of light structural changes in B-mode ultrasound images in association with mild
neovascularization (determined with Power Doppler images) or the presence of moderate/severe structural changes with or without neovascularization. Up to now, the structural changes and neovascularization of the tendon are evaluated qualitatively by visual inspection of ultrasound images. The aim of this study is to investigate the capability of a quantitative texture-based approach to determine tendon abnormality of “pallapugno” players. B-mode ultrasound images of the patellar tendon were acquired in 14 players and quantitative texture parameters were calculated within a Region of Interest (ROI) of both the non-dominant and the dominant tendon. A total of 90 features were calculated for each ROI, including 6 first-order descriptors, 24 Haralick features, and 60 higher-order spectra and entropy features. These features on the dominant and non-dominant side were used to perform a multivariate linear regression analysis (MANOVA) and our results show that the descriptors can be effectively used to determine tendon abnormality and, more importantly, the occurrence of subclinical tendinopathy.
Selective fusion for idiopathic scoliosis review by dr.shashidhar b kDr. Shashidhar B K
SCOLIOISIS SURGEON BANGALORE
SCOLIOSIS SURGEON INDIA
Website: http://spinesurgeonbangalore.com/
My goal is to provide spine care with a patient centeric-holistic approach in Bangalore, encompassing all aspects of non-operative and operative management of spinal disorders with special interest in the management of spinal deformities (scoliosis and kyphosis).
Bangalore Spine Specilaist Clinic. For Appointment contact : Call: 08025442552( 9 am to 9 pm). Whatsapp: +919448311068. Email: drshashidharbk@gmail.com.
A Comparative Study of the Clinical and Functional Outcome Anterior Cruciate ...TheRightDoctors
A Comparative Study of the Clinical and Functional Outcome Anterior Cruciate Ligament Reconstruction Using Transportal and Transtibial Approach for Femoral Tunnel Drilling-Dr. Adarsh Reddy
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
HOT NEW PRODUCT! BIG SALES FAST SHIPPING NOW FROM CHINA!! EU KU DB BK substit...GL Anaacs
Contact us if you are interested:
Email / Skype : kefaya1771@gmail.com
Threema: PXHY5PDH
New BATCH Ku !!! MUCH IN DEMAND FAST SALE EVERY BATCH HAPPY GOOD EFFECT BIG BATCH !
Contact me on Threema or skype to start big business!!
Hot-sale products:
NEW HOT EUTYLONE WHITE CRYSTAL!!
5cl-adba precursor (semi finished )
5cl-adba raw materials
ADBB precursor (semi finished )
ADBB raw materials
APVP powder
5fadb/4f-adb
Jwh018 / Jwh210
Eutylone crystal
Protonitazene (hydrochloride) CAS: 119276-01-6
Flubrotizolam CAS: 57801-95-3
Metonitazene CAS: 14680-51-4
Payment terms: Western Union,MoneyGram,Bitcoin or USDT.
Deliver Time: Usually 7-15days
Shipping method: FedEx, TNT, DHL,UPS etc.Our deliveries are 100% safe, fast, reliable and discreet.
Samples will be sent for your evaluation!If you are interested in, please contact me, let's talk details.
We specializes in exporting high quality Research chemical, medical intermediate, Pharmaceutical chemicals and so on. Products are exported to USA, Canada, France, Korea, Japan,Russia, Southeast Asia and other countries.
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
The six minute walk test for patients with lumbar spinal stenosis
1. INTRODUCTION
Impairment of ambulation is a crucial component of some impairments for lumbar spinal stenosis (LSS). The 6-minute walk
test (6MWT) has been validated as a laboratory walking test and is increasingly recognized as a meaningful outcome
measure in patients with peripheral arterial disease. However, the 6MWT has not been validated for the patients with LSS. In
this study, we evaluated the criterion-related validity of 6MWT by examining a correlation with a self-report questionnaire.
METHODS
Subjects following rehabilitation after the surgery of LSS (Sex: male/female 28/47, Age: 71±8 y.o) completed Zurich
Claudication Questionnaire (ZCQ) and performed the 6MWT before the surgery and three months after the surgery.
Correlation with ZCQ subscales (symptom severity and physical function was examined to evaluate the criterion-related
validity of the 6MWT.
RESULTS
There were significant improvements in ZCQ score (p<0.001) and parameters (distance and walk speed) of the 6MWT
(p<0.001) after the surgery(Figure 1). In before and after the surgery, the parameters of the 6MWT correlated weakly with the
symptom severity scale and with the physical function scale(Table 1).
CONCLUSION
It was reported ZCQ has the validity and the reliability for the evaluation of the patients with LSS. In this study, there were
weak correlation between ZCQ subscales and the parameters of the 6MWT both before and after the surgery. Therefore,
6MWT has the certain criterion-related validity in the walking ability evaluation of patients with LSS. Furthermore, the 6MWT
may evaluate different walking performance from physical function scale of ZCQ.
REFERENCE
•Konno S(2007)Development of a clinical diagnosis support tool to identify patients with lumbar spinal stenosis.Eur Spine J. 16(11):1951-7.
•Tomkins CC(2009)A criterion measure of walking capacity in lumbar spinal stenosis and its comparison with a treadmill protocol.Spine 15;34(22):2444-9.
•Tomkins-Lane CC(2010)Validity and reproducibility of self-report measures of walking capacity in lumbar spinal stenosis. Spine 35(23):2097-102.
•Conway J(2011)Walking assessment in people with lumbar spinal stenosis: capacity, performance, and self-report measures. Spine J. 11(9):816-23.
•Rainville J(2012)Quantification of walking ability in subjects with neurogenic claudication from lumbar spinal stenosis--a comparative study.Spine J. 12(2):101-9.
CONFLICT OF INTEREST
Companies etc. with a conflict of interest relation with the presentation which should be disclosed.
The six-minute walk test for patients
with lumbar spinal stenosis
Imoo. Y1, Mamizuka. N2, Kubota. Y1, Suzuki. H3 Hirano. A2, Fujie. K4, Hashimoto. K4, Nakata. Y4, Sakane. M4,
Yamazaki. M4
1.Department of Rehabilitation, University of Tsukuba, Mito Clinical Education and Training Center, Mito Kyodo General Hospital
2.Department of Orthopaedic Surgery, University of Tsukuba, Mito Clinical Education and Training Center, Mito Kyodo General Hospital
3.Department of Health and Sports Science, University of Juntendo 4.Faculty of Medicine, University of Tsukuba
Before the surgery After the surgery
Figure 1. The change between before and after the surgery.
*These results suggest the change in (1)walk distance, (2)walk speed,
(3)severity and (4)physical function.
p<0.001 p<0.001
p<0.001 p<0.001
(1) (2)(1)
(3) (4)
symptom severity physical function
Before distance r=-0.30
(p=0.008)
r=-0.36
(p=0.002)
speed r=-0.25
(p=0.028)
r=-0.30
(p=0.009)
After distance r=-0.22
(p=0.064)
r=-0.33
(p=0.004)
speed r=-0.27
(p=0.020)
r=-0.34
(p=0.002)
Table 1. The correlation with parameter of 6MWT and
ZCQ subscales.
*These results are presented by Pearson product-moment correlation
coefficient(r) with p-value(p).
Email: rugby.imoo@gmail