The document summarizes a trial called the CO-OPS Trial which studied the effects of fatigue on radiologists' performance in breast cancer screening. It tested whether reversing the order radiologists read screening mammograms (to optimize performance patterns) and taking breaks could help address the normal vigilance decrement seen in tasks requiring sustained attention over long periods. The document outlines the trial methods, results, and interpretations that will be presented on fatigue and changing case order in breast screening radiology.