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The Johnson and Johnson COVID- 9 vaccine consists of inactivated adenovirus that has been
altered to contain genetic information encoding SARS-CoV-2 surface spike proteins. The virus
targets and delivers this genetic information to the cells of our respiratory tract, which produce
benign SARS-CoV-2 surface spike proteins but are effective for training our immune system to
defend us against SARS-CoV-2. Based on this information and your knowledge of viruses in
general, could T4 bacteriophage be used in place of adenovirus in the same way? Explain.

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  • 1. The Johnson and Johnson COVID- 9 vaccine consists of inactivated adenovirus that has been altered to contain genetic information encoding SARS-CoV-2 surface spike proteins. The virus targets and delivers this genetic information to the cells of our respiratory tract, which produce benign SARS-CoV-2 surface spike proteins but are effective for training our immune system to defend us against SARS-CoV-2. Based on this information and your knowledge of viruses in general, could T4 bacteriophage be used in place of adenovirus in the same way? Explain.