The document discusses two myths about using VMware vSphere 5 for cloud deployments. The first myth is that it makes more sense to deploy vSphere 5 over NFS instead of Fibre Channel or iSCSI. While NFS provides flexibility and cost savings, it has disadvantages in reliability and performance compared to block storage options. The second myth is that Storage DRS and Profile-Driven Storage are sufficient to meet the requirements of tier 1 applications. However, Storage DRS has limitations and may not provide the guaranteed performance and availability needed for critical applications. The document recommends evaluating both block and file storage options and using automated tiering to optimize performance and costs.