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La Talidomida 
Malformacions congènites 
Natàlia Barceló, Melissa Barnuevo, Mar Batlle, Daniel 
Joel Belda, Aleix Benavent i Mireia Benito
Índex 
1. Introducció 
2. Efectes Adversos 
3. La química de la 
molècula 
4. Malaltia genètica? 
5. En l’actualitat 
5. Vídeo d’un afectat 
6. Conclusions
Introducció 
TALIDOMIDA: Fàrmac sedant 
Efectes Positius 
- Ansietat 
- Insomni 
- Nàusees 
- Vòmits 
Efectes Negatius 
MALFORMACIONS
Efectes adversos 
MALFORMACIONS 
Focomèlia: 
Unió directa de les mans amb les 
espatlles, i dels peus al maluc.
La química de la molècula 
Quiral: 
Dues formes de 
simetria 
especular 
Teratògen: 
Dóna 
malformacions 
en el fetus o en el 
nounat
Malaltia genètica? 
Congènita Genètica 
Teratògen Sí Si 
Mutàgen No Sí
En l’actualitat 
Associacions d’afectats que reclamen indemnitzacions i 
casos per resoldre. 
Augment del control abans de la comercialització 
Investigació: Efectiu en casos de lepra, mieloma múltiple, 
càncers, etc.
Vídeo 
http://www.rtve.es/noticias/20110620/184- 
afectados-talidomida-piden-156-millones-dos-laboratorios/ 
442265.shtml
Eix cronològic 
Llançament 
1957 
Retirada del 
mercat 
Utilitat en 
casos de 
lepra 
1961 
Primeres 
associacions 
1972 
Primera indemnització 
1990
Conclusions 
+ SEGURETAT
Gràcies per la vostra atenció.

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Talidomida: Malformacions congènites