GxAlert Papua New Guinea Case Study 072518SystemOne
GxAlert's use in Papua New Guinea for disease surveillance and response. Initially used for Tuberculosis response, device management and second-line drug forecasting and stockage.
Bangladesh case study on how we implemented a connected diagnostics solution using GxAlert for infectious disease surveillance, TB program optimization and leveraging diagnostic data.
GxAlert for Real-time Management and Strengthening of Remote GeneXpert Networ...SystemOne
Real-time monitoring of GeneXpert machines can contribute to reduced error rates and shorter turnaround
times for module replacement and can improve the overall
maintenance of the machines. Emails and SMS alerts can speed
up treatment initiation. The NTP now gets SMS alerts and emails for DR-TB patient enrollment; stockout and error (>5%) rates; critical module errors; and monthly MDR reports to ensure better
connections among diagnosis, enrollment, and treatment.
Feasibility of an SMS intervention to deliver tuberculosis testing results in...SystemOne
Pre-treatment loss to follow-up is common for patients diagnosed with tuberculosis (TB) in high-burden countries. Delivering test results by SMS is increasingly being considered as a solution, but there is limited information about its feasibility as a public health tool in low resourced settings. It was found that reporting Xpert results via automated SMS is technically feasible and results in approximately half of patients receiving their test results immediately. Additional research should be done to address process inefficiencies in order to maximize impact of this technology and link its successful utilization to improved patient outcomes.
Accelerating the translation of medical research - 27 JuneInnovation Agency
Slides from the event focusing on translational research in Liverpool and North of England and why companies are establishing and growing operations in the region.
Beating Bugs with Big Data: Harnessing HPC to Realize the Potential of Genomi...Tom Connor
Introducing the HPC challenges associated with developing a set of clinical microbial genomics services in the NHS in Wales. Demonstrating the potential of these technologies, and the impact it is already having for the patients of the Welsh NHS.
GxAlert Papua New Guinea Case Study 072518SystemOne
GxAlert's use in Papua New Guinea for disease surveillance and response. Initially used for Tuberculosis response, device management and second-line drug forecasting and stockage.
Bangladesh case study on how we implemented a connected diagnostics solution using GxAlert for infectious disease surveillance, TB program optimization and leveraging diagnostic data.
GxAlert for Real-time Management and Strengthening of Remote GeneXpert Networ...SystemOne
Real-time monitoring of GeneXpert machines can contribute to reduced error rates and shorter turnaround
times for module replacement and can improve the overall
maintenance of the machines. Emails and SMS alerts can speed
up treatment initiation. The NTP now gets SMS alerts and emails for DR-TB patient enrollment; stockout and error (>5%) rates; critical module errors; and monthly MDR reports to ensure better
connections among diagnosis, enrollment, and treatment.
Feasibility of an SMS intervention to deliver tuberculosis testing results in...SystemOne
Pre-treatment loss to follow-up is common for patients diagnosed with tuberculosis (TB) in high-burden countries. Delivering test results by SMS is increasingly being considered as a solution, but there is limited information about its feasibility as a public health tool in low resourced settings. It was found that reporting Xpert results via automated SMS is technically feasible and results in approximately half of patients receiving their test results immediately. Additional research should be done to address process inefficiencies in order to maximize impact of this technology and link its successful utilization to improved patient outcomes.
Accelerating the translation of medical research - 27 JuneInnovation Agency
Slides from the event focusing on translational research in Liverpool and North of England and why companies are establishing and growing operations in the region.
Beating Bugs with Big Data: Harnessing HPC to Realize the Potential of Genomi...Tom Connor
Introducing the HPC challenges associated with developing a set of clinical microbial genomics services in the NHS in Wales. Demonstrating the potential of these technologies, and the impact it is already having for the patients of the Welsh NHS.
Data Infrastructure for Real-time Analysis to provide Health InsightsQuahog Life Sciences
Illustrating how a well planned data infrastructure designed for real-time and continuous learning can have multiple advantages, facilitating better preventive strategies
Real world clinical medical data. Corporate presentation of Ad Scientiam which is a startup specialized in real life data acquisition during clinical trials.
Learn more at : www.adscientiam.com
Clinical trial data wants to be free: Lessons from the ImmPort Immunology Dat...Barry Smith
Presentation to the Clinical and Research Ethics Seminar, Clinical and Translational Science Center, Buffalo, January 21, 2014
https://immport.niaid.nih.gov/
http://youtu.be/booqxkpvJMg
David Snead on The use of digital pathology in the primary diagnosis of histo...Cirdan
Recent developments in digital pathology enable the rapid scanning of microscope slides at high resolution, making the digitisation of histopathology slides for routine diagnosis purposes feasible. An important initial step in the wider adoption of this technology is the establishment of validation data assessing how effective pathologists are using digital workstations in comparison to conventional light microscopes and glass slides when examining cases for primary diagnosis. I will report on the first study sufficiently powered to demonstrate a statistically valid equivalent (i.e. non-inferior) performance of digital pathology (DP) against standard glass slide (GS) microscopy. This study examined a total of 3,017 cases were included, generating 10,138 slides, which when scanned resulted in a digital archive of 2.45 terabytes. As well as demonstrating non-inferiority of digital in comparison to glass slides the study was useful in establishing rules for slide scanning and identifying areas where digital pathology has limitations and needs to be used with caution.
Finally the presentation covers the impact adopting digital pathology will have on diagnostic laboratories, the economics of these changes and where these changes are most likely to benefit patients.
TreatmentMAP™
TreatmentMAP supports physicians in optimizing their treatment decisions, even for cancer patients in advanced stages of cancer, or when all of the standard treatment options for a patient have been exhausted.
Who needs fast data? - Journal for Clinical Studies KCR
How “no news” during the life of a trial is bad news, and what data management (among other things) can do to help when ensuring access to fast data? Get to know this and more about smart e-solutions in the newest article of Kaia Koppel, Associate Director, Biometrics & Clinical Trial Data Execution Systems at KCR, in the recent issue of Journal for Clinical Studies (p.40-21).
Dr. Jules Mitchel, President of Target Health, delivered this presentation on the new FDA Guidance on the use of the electronic health record for clinical research at the North American eClinical Forum Autumn Meeting on October 2, 2018.
Presentation Alliance of European Life Sciences Law Firms
(Julian Hitchcock and Sofie van der Meulen) on legal aspects of big data in pharma. Topics: privacy, IP, medical devices and IVD.
Data Infrastructure for Real-time Analysis to provide Health InsightsQuahog Life Sciences
Illustrating how a well planned data infrastructure designed for real-time and continuous learning can have multiple advantages, facilitating better preventive strategies
Real world clinical medical data. Corporate presentation of Ad Scientiam which is a startup specialized in real life data acquisition during clinical trials.
Learn more at : www.adscientiam.com
Clinical trial data wants to be free: Lessons from the ImmPort Immunology Dat...Barry Smith
Presentation to the Clinical and Research Ethics Seminar, Clinical and Translational Science Center, Buffalo, January 21, 2014
https://immport.niaid.nih.gov/
http://youtu.be/booqxkpvJMg
David Snead on The use of digital pathology in the primary diagnosis of histo...Cirdan
Recent developments in digital pathology enable the rapid scanning of microscope slides at high resolution, making the digitisation of histopathology slides for routine diagnosis purposes feasible. An important initial step in the wider adoption of this technology is the establishment of validation data assessing how effective pathologists are using digital workstations in comparison to conventional light microscopes and glass slides when examining cases for primary diagnosis. I will report on the first study sufficiently powered to demonstrate a statistically valid equivalent (i.e. non-inferior) performance of digital pathology (DP) against standard glass slide (GS) microscopy. This study examined a total of 3,017 cases were included, generating 10,138 slides, which when scanned resulted in a digital archive of 2.45 terabytes. As well as demonstrating non-inferiority of digital in comparison to glass slides the study was useful in establishing rules for slide scanning and identifying areas where digital pathology has limitations and needs to be used with caution.
Finally the presentation covers the impact adopting digital pathology will have on diagnostic laboratories, the economics of these changes and where these changes are most likely to benefit patients.
TreatmentMAP™
TreatmentMAP supports physicians in optimizing their treatment decisions, even for cancer patients in advanced stages of cancer, or when all of the standard treatment options for a patient have been exhausted.
Who needs fast data? - Journal for Clinical Studies KCR
How “no news” during the life of a trial is bad news, and what data management (among other things) can do to help when ensuring access to fast data? Get to know this and more about smart e-solutions in the newest article of Kaia Koppel, Associate Director, Biometrics & Clinical Trial Data Execution Systems at KCR, in the recent issue of Journal for Clinical Studies (p.40-21).
Dr. Jules Mitchel, President of Target Health, delivered this presentation on the new FDA Guidance on the use of the electronic health record for clinical research at the North American eClinical Forum Autumn Meeting on October 2, 2018.
Presentation Alliance of European Life Sciences Law Firms
(Julian Hitchcock and Sofie van der Meulen) on legal aspects of big data in pharma. Topics: privacy, IP, medical devices and IVD.
GxAlert Monitors and Reduces High Testing Error Rates in Nigeria's GeneXpert ...SystemOne
Presentation on the use of SystemOne's GxAlert tool in Nigeria, for monitoring reducing diagnostic errors and accelerating positive outcomes in TB.
Published courtesy of Kehinde Jimoh Agbaiyero, Senior Technical Advisor - TB, Abt Associates
Early diagnosis of infectious diseases and monitoring of community health are essential
for delivering cost-effective healthcare solutions. Healthcare delivery in developing coun-
tries have many challenges because they do not have enough resources for meeting the
healthcare needs, and they lack testing lab infrastructures in communities. It is necessary that a solution must be developed to safeguard the impacted communities. It has
been proven that Point-Of-Care (POC) testing can be considered as one of the ways to
resolve the crisis in healthcare delivery in these communities. The term 'POC testing'
has been used in many contexts. Use case, where a passenger in an autonomous vehicle
is driven to the nearest hospital for an emergency treatment due to an alert received by
the health monitoring system in the car. The POC that the research exploring is for
the use for a remote patient who does not have access to lab testing facilities because of
the social and economic conditions in that community.
The POC testing is a mission critical processes in which the patient conduct tests in a
home environment, as opposed to the tests undertaken otherwise in a laboratory facility
and it needs a communication system of architecture support which the research refers
as POCT system. The research looked at the requirements and made recommendations concerning critical aspects: requirements gathering for POCT system, design and
development methods of secure communication architecture, finding a suitable strategy
for testing the system and project managing the end-2-end process.
Data security is another critical factor in healthcare data. The research came up with
secure data communication architecture and processes for the system. A secure data
storage for the test results are needed, and the research came up with an architecture
for cloud storage. Deployment and expansion of the secure communication system are
essential for practical use cases based on community needs, and a scalable communication
architecture was developed to support the objective.
Presentation by Rahija and Mtui at the 2016 AAPOR session on Monitoring data quality during fieldwork in international CAPI surveys. This was not presented at AAPOR although the speakers were part of the program.
This article describes the use of the SMS printer as part of the Expedited Results System (ERS) which greatly improves the quality of Mozambique early infant diagnosis program.
The Role of Connected Diagnostics in Strengthening Regional, National and Con...SystemOne
Although numerous disease intelligence and surveillance systems exist, they are plagued with inaccurate or untimely data. We contend, furthermore, that it was this lack of data quality – and not
the lack of surveillance systems or networks – that prevented the global community from acting earlier in response to the Ebola outbreak in 2014–2016. The new field of ‘connected diagnostics’ is one solution to this concern, as it automates data collection directly from the diagnostic instruments to multiple levels of stakeholders for real-time decision-making and policy response.
This article details how the intervention of ‘connected diagnostics’ could solve the primary underlying failure in existing surveillance systems – the lack of accurate and timely data – to enable
difficult political decisions earlier. The use of connectivity solutions can enable critical health and operational data to empower the Africa CDC, regional hubs, and each country with a consistent
and automated data feed while still maintaining country privacy and controls.
Racing for results: lessons learnt in improving the efficiency of HIV VL and ...SystemOne
In pursuit of the 90–90–90 goals, emphasis has been placed on accelerating centralized laboratory HIV viral load testing of a population that is largely rural and decentralized. Successful
outcome requires effective specimen transport, laboratory testing, and results delivery. This paper focuses on the methods currently employed for results delivery. New innovations in this area are
yielding mixed results; we analyze different approaches and estimate the impact of each on achieving the third ‘90.’
Welcome to Secret Tantric, London’s finest VIP Massage agency. Since we first opened our doors, we have provided the ultimate erotic massage experience to innumerable clients, each one searching for the very best sensual massage in London. We come by this reputation honestly with a dynamic team of the city’s most beautiful masseuses.
India Clinical Trials Market: Industry Size and Growth Trends [2030] Analyzed...Kumar Satyam
According to TechSci Research report, "India Clinical Trials Market- By Region, Competition, Forecast & Opportunities, 2030F," the India Clinical Trials Market was valued at USD 2.05 billion in 2024 and is projected to grow at a compound annual growth rate (CAGR) of 8.64% through 2030. The market is driven by a variety of factors, making India an attractive destination for pharmaceutical companies and researchers. India's vast and diverse patient population, cost-effective operational environment, and a large pool of skilled medical professionals contribute significantly to the market's growth. Additionally, increasing government support in streamlining regulations and the growing prevalence of lifestyle diseases further propel the clinical trials market.
Growing Prevalence of Lifestyle Diseases
The rising incidence of lifestyle diseases such as diabetes, cardiovascular diseases, and cancer is a major trend driving the clinical trials market in India. These conditions necessitate the development and testing of new treatment methods, creating a robust demand for clinical trials. The increasing burden of these diseases highlights the need for innovative therapies and underscores the importance of India as a key player in global clinical research.
R3 Stem Cells and Kidney Repair A New Horizon in Nephrology.pptxR3 Stem Cell
R3 Stem Cells and Kidney Repair: A New Horizon in Nephrology" explores groundbreaking advancements in the use of R3 stem cells for kidney disease treatment. This insightful piece delves into the potential of these cells to regenerate damaged kidney tissue, offering new hope for patients and reshaping the future of nephrology.
Global launch of the Healthy Ageing and Prevention Index 2nd wave – alongside...ILC- UK
The Healthy Ageing and Prevention Index is an online tool created by ILC that ranks countries on six metrics including, life span, health span, work span, income, environmental performance, and happiness. The Index helps us understand how well countries have adapted to longevity and inform decision makers on what must be done to maximise the economic benefits that comes with living well for longer.
Alongside the 77th World Health Assembly in Geneva on 28 May 2024, we launched the second version of our Index, allowing us to track progress and give new insights into what needs to be done to keep populations healthier for longer.
The speakers included:
Professor Orazio Schillaci, Minister of Health, Italy
Dr Hans Groth, Chairman of the Board, World Demographic & Ageing Forum
Professor Ilona Kickbusch, Founder and Chair, Global Health Centre, Geneva Graduate Institute and co-chair, World Health Summit Council
Dr Natasha Azzopardi Muscat, Director, Country Health Policies and Systems Division, World Health Organisation EURO
Dr Marta Lomazzi, Executive Manager, World Federation of Public Health Associations
Dr Shyam Bishen, Head, Centre for Health and Healthcare and Member of the Executive Committee, World Economic Forum
Dr Karin Tegmark Wisell, Director General, Public Health Agency of Sweden
One of the most developed cities of India, the city of Chennai is the capital of Tamilnadu and many people from different parts of India come here to earn their bread and butter. Being a metropolitan, the city is filled with towering building and beaches but the sad part as with almost every Indian city
QA Paediatric dentistry department, Hospital Melaka 2020Azreen Aj
QA study - To improve the 6th monthly recall rate post-comprehensive dental treatment under general anaesthesia in paediatric dentistry department, Hospital Melaka
Defecation
Normal defecation begins with movement in the left colon, moving stool toward the anus. When stool reaches the rectum, the distention causes relaxation of the internal sphincter and an awareness of the need to defecate. At the time of defecation, the external sphincter relaxes, and abdominal muscles contract, increasing intrarectal pressure and forcing the stool out
The Valsalva maneuver exerts pressure to expel faeces through a voluntary contraction of the abdominal muscles while maintaining forced expiration against a closed airway. Patients with cardiovascular disease, glaucoma, increased intracranial pressure, or a new surgical wound are at greater risk for cardiac dysrhythmias and elevated blood pressure with the Valsalva maneuver and need to avoid straining to pass the stool.
Normal defecation is painless, resulting in passage of soft, formed stool
CONSTIPATION
Constipation is a symptom, not a disease. Improper diet, reduced fluid intake, lack of exercise, and certain medications can cause constipation. For example, patients receiving opiates for pain after surgery often require a stool softener or laxative to prevent constipation. The signs of constipation include infrequent bowel movements (less than every 3 days), difficulty passing stools, excessive straining, inability to defecate at will, and hard feaces
IMPACTION
Fecal impaction results from unrelieved constipation. It is a collection of hardened feces wedged in the rectum that a person cannot expel. In cases of severe impaction the mass extends up into the sigmoid colon.
DIARRHEA
Diarrhea is an increase in the number of stools and the passage of liquid, unformed feces. It is associated with disorders affecting digestion, absorption, and secretion in the GI tract. Intestinal contents pass through the small and large intestine too quickly to allow for the usual absorption of fluid and nutrients. Irritation within the colon results in increased mucus secretion. As a result, feces become watery, and the patient is unable to control the urge to defecate. Normally an anal bag is safe and effective in long-term treatment of patients with fecal incontinence at home, in hospice, or in the hospital. Fecal incontinence is expensive and a potentially dangerous condition in terms of contamination and risk of skin ulceration
HEMORRHOIDS
Hemorrhoids are dilated, engorged veins in the lining of the rectum. They are either external or internal.
FLATULENCE
As gas accumulates in the lumen of the intestines, the bowel wall stretches and distends (flatulence). It is a common cause of abdominal fullness, pain, and cramping. Normally intestinal gas escapes through the mouth (belching) or the anus (passing of flatus)
FECAL INCONTINENCE
Fecal incontinence is the inability to control passage of feces and gas from the anus. Incontinence harms a patient’s body image
PREPARATION AND GIVING OF LAXATIVESACCORDING TO POTTER AND PERRY,
An enema is the instillation of a solution into the rectum and sig
Navigating Challenges: Mental Health, Legislation, and the Prison System in B...Guillermo Rivera
This conference will delve into the intricate intersections between mental health, legal frameworks, and the prison system in Bolivia. It aims to provide a comprehensive overview of the current challenges faced by mental health professionals working within the legislative and correctional landscapes. Topics of discussion will include the prevalence and impact of mental health issues among the incarcerated population, the effectiveness of existing mental health policies and legislation, and potential reforms to enhance the mental health support system within prisons.
CRISPR-Cas9, a revolutionary gene-editing tool, holds immense potential to reshape medicine, agriculture, and our understanding of life. But like any powerful tool, it comes with ethical considerations.
Unveiling CRISPR: This naturally occurring bacterial defense system (crRNA & Cas9 protein) fights viruses. Scientists repurposed it for precise gene editing (correction, deletion, insertion) by targeting specific DNA sequences.
The Promise: CRISPR offers exciting possibilities:
Gene Therapy: Correcting genetic diseases like cystic fibrosis.
Agriculture: Engineering crops resistant to pests and harsh environments.
Research: Studying gene function to unlock new knowledge.
The Peril: Ethical concerns demand attention:
Off-target Effects: Unintended DNA edits can have unforeseen consequences.
Eugenics: Misusing CRISPR for designer babies raises social and ethical questions.
Equity: High costs could limit access to this potentially life-saving technology.
The Path Forward: Responsible development is crucial:
International Collaboration: Clear guidelines are needed for research and human trials.
Public Education: Open discussions ensure informed decisions about CRISPR.
Prioritize Safety and Ethics: Safety and ethical principles must be paramount.
CRISPR offers a powerful tool for a better future, but responsible development and addressing ethical concerns are essential. By prioritizing safety, fostering open dialogue, and ensuring equitable access, we can harness CRISPR's power for the benefit of all. (2998 characters)
Struggling with intense fears that disrupt your life? At Renew Life Hypnosis, we offer specialized hypnosis to overcome fear. Phobias are exaggerated fears, often stemming from past traumas or learned behaviors. Hypnotherapy addresses these deep-seated fears by accessing the subconscious mind, helping you change your reactions to phobic triggers. Our expert therapists guide you into a state of deep relaxation, allowing you to transform your responses and reduce anxiety. Experience increased confidence and freedom from phobias with our personalized approach. Ready to live a fear-free life? Visit us at Renew Life Hypnosis..
How many patients does case series should have In comparison to case reports.pdfpubrica101
Pubrica’s team of researchers and writers create scientific and medical research articles, which may be important resources for authors and practitioners. Pubrica medical writers assist you in creating and revising the introduction by alerting the reader to gaps in the chosen study subject. Our professionals understand the order in which the hypothesis topic is followed by the broad subject, the issue, and the backdrop.
https://pubrica.com/academy/case-study-or-series/how-many-patients-does-case-series-should-have-in-comparison-to-case-reports/
1. CASE STUDY: SWAZILAND
FROM DATA TO IMPACT
Implementation summary
Country Swaziland
Laboratories 28
Diseases MTB, MDR TB
Devices &
Assays
GeneXpert, MTB and
MDR TB
Funding
Partner
Global Fund
Local Heroes: Lead:
Themba Dlamini,
Program Manager, NTP
Dr. Welile Sikhondze,
Technical Advisor and
Research Coordinator,
NTP
Sindisiwe Dlamini,
Chief Laboratory
Technologist, SHLS
Team Members:
Doctor Busizwe
Sibandze
Drug Resistance Survey
Laboratory Manager,
NTP
Tumiso Matumba
Information Technology,
National ICT Officer, NTP
Thando Mabuza,
Assistant ICT Officer, NTP
Derrick Khumalo
Principal Technologist &
SHLS/NTP Laboratory
Coordinator
Sylvester Moyo
Laboratory Information
System Manager, CHAI
Tufuma Zanamwe
Laboratory Information
System Manager, ICAP
Pinky Kubheka
Regional Laboratory
Advisor, ICAP
Justice Makuni
Software Developer,
HMIS
THE CHALLENGE:
MODERN DIAGNOSTICS AND TRAINED STAFF HAMPERED BY DISTANCE AND
COMMUNICATION ISSUES
The Swaziland NTP understood that despite having a fleet of new GeneXpert
diagnostic devices and a skilled staff, they would not realize the full potential of
these new devices without a robust device management platform. To maximize
the use of GeneXperts, and eventually other diagnostics, the NTP needed to:
• understand utilization;
• figure out which errors were happening and why;
• implement rapid response to diagnoses;
• deploy targeted training resources efficiently; and,
• manage a fleet of expensive devices over the long term.
A robust device management connectivity platform could help realize the new
technology’s promise. In addition to the immediate issues of improving time to
treatment and system optimization, the Swaziland NTP wanted to take advantage
of the platform to:
Manage inventory:
• Optimizing procurement and utilization
• Reducing wastage
Manage devices:
• Remotely, identify and fix device errors rapidly
• Maintain devices and keep warranties up to date, and reduce
costs over time
Collect and analyze data, to:
• understand disease trends and
patterns
• use custom fields to optimize
laboratory processes and
patient care
• ensure data privacy and control
• automate time-consuming
reports
Doctor Busizwe Sibandze installs
GxAlert at the Raleigh Fitkin Memorial
Hospital laboratory with supervision
from Tumiso Matumba and
SystemOne’s Max Strong.
2. CASE STUDY: SWAZILAND
SOLUTION
The local NTP team helped SystemOne set a new record for the number of laboratories interfaced in the roll-out training: 15 facilities in
total were connected by the in-country team (9 within a single day).
During the Advanced Administration training, the NTP team presented the benefits, use and components of the GxAlert platform to
members of the M&E team whom were unable to attend the Basic Administration training. The team then configured all baseline
notifications for the GxAlert platform for:
• New Rifampicin Resistant Cases
• Drug Resistance Survey Cases
• Low-Stock at Facilities
• Device Offline
• Automated Weekly Drug Resistance Survey Cases Report.
A Data Collection Plan workshop enabled the NTP to set the initial baseline notifications using the current lab request form as a template.
And, a Data Control Plan began taking shape with a core team of NTP personnel.
WORKING WITH A TALENTED LOCAL NTP TEAM MINIMIZED INITIAL CHALLENGES
Nearly every technology deployment involves difficulties: from contracting and funding delays, to shipping equipment and working
with import and customs authorities. The delays can last weeks, months or years.
In Swaziland, uncontrollable delays specific to shipping the routers required for connectivity nearly caused a shift in schedule. The
routers arrived the same day as the SystemOne Implementation Team, who ensured that the shipping delays did not impact any of the
setup and configuration timelines.
Other challenges that SystemOne and the NTP team resolved included:
• Additional steps for LIS configuration which requires higher level of IT skill than standard users.
• A number of facilities had viruses infecting the GeneXpert computers.
• Poor GSM signal strength challenges in remote facilities.
SUCCESSES & MOVING FORWARD
• SystemOne and the NTP had set a target of 5 laboratory installations as part of the in-country visit. The team managed to
successfully install GxAlert at 15 facilities over a 3-day period. (Nearly 50% of the national rollout).
• The technology collected 48,523 results, digitally, during the in-country period.
• With the skilled NTP staff, the SystemOne team managed to connect even laboratories that had a Laboratory Information
System which presented some interface challenges.
• Installation and Administration training with representatives of the NTP IT and M&E Group included attendees from SHLS and
CHAI-Swaziland, and helped give the NTP a road-map for moving forward with GxAlert.
• GxAlert has been useful in the monitoring of sample flow and patient enrollment in the drug resistance survey underway.
SystemOne continues to support the Swaziland implementation, and will be working with the NTP team to aggregate and analyze
GxAlert data. This will lead to specific recommendations for how to optimize cartridge procurement and inventory, where to focus
additional training efforts, how to best manage devices specific to warranty and maintenance, and how to use the data from connected
devices to help improve health outcomes.
In conclusion: GxAlert implementation was successful with at least 50% devices installed with a 3 day period. In addition, the GxAlert
notification system has played a key role in the monitoring of sample flow and patient enrollment in the current TB drug resistance
survey.