The document provides six tips for reducing stress in the office:
1) Eat dark chocolate which contains substances like theobromine and magnesium that can reduce stress levels.
2) Use a gadget called Emwave which monitors breathing to train the user to think more clearly and feel less reactive during stressful situations.
3) Try a mat called a Yantra Mat which uses acupressure points to release endorphins and oxytocin to induce relaxation.
4) Watch short meditation videos or use calming screensavers to take brief breaks from work stresses.
5) Improve lighting conditions which research shows can boost alertness and productivity while reducing stress.
6) Manage one's
The document discusses various stress-relieving gadgets and techniques that employers are offering to employees, such as microcurrent devices that send electrical currents through the earlobes to relax the brain, breathing reminders to reduce stress and anxiety, and stress-level indicators. It also covers the growing problem of work-related stress causing health issues like burnout, and more enlightened employers providing counselling and resilience training through employee assistance programs to help manage stress.
The document discusses three travel opportunities: 1) A two-week trip to Mexico exploring Mayan culture, jungles, and beaches for £640 per person; 2) A trip to Stockholm around Christmas including flights, accommodation, and transportation for £614 per couple; 3) A bidding auction on a one-week holiday in southern France, where the highest bidder wins the week and an additional free week, with proceeds donated to charity.
This document provides travel recommendations for Sydney, Australia. It recommends taking a boat tour around the harbor like celebrity Katy Perry. It suggests staying at the Medusa hotel, a refurbished Victorian mansion, and eating at the Quay restaurant on the harbor. The document also provides details on attending the Rugby League World Cup and getting views of the city from the Sydney Harbour Bridge.
Queensland floods by Daisy Dumas, Australian Geographicdaisydumas
The document summarizes the impacts of recent flooding in southeast Queensland on local wildlife. During floods, many animals are threatened by being washed away, relocated, or drowned if they cannot swim, fly, or climb to higher ground. Tree-dwelling animals like koalas were able to survive if trees remained standing. In the aftermath, animals must find new food sources and migration routes as the landscape changes, increasing predation for some. Marine species are also affected by changes in water quality after floods. The AG Society is fundraising to track whale sharks and protect seagrass beds impacted by flood runoff.
Nendaz is a Swiss ski resort located in the Four Valleys region that is less crowded than its neighboring resort of Verbier. It has extensive ski terrain with 410km of runs served by 92 lifts across eight resorts. Nendaz offers high-quality self-catered accommodation options that are family-friendly with 80% owned by locals. It has a more relaxed atmosphere than Verbier but still offers amazing off-piste skiing opportunities like the renowned Mont Fort run, as well as night skiing events.
Peter Siddle, an Australian cricketer, almost ended his career as a child by chopping off his own finger while woodchopping. As a youth he was an accomplished woodchopper, coming in second place in competitions. Despite chopping off his finger, doctors were able to reattach it with no painkillers. On his birthday, Siddle took six wickets for Australia in the Ashes match against England, including a hat-trick, demonstrating the determination he learned as a youth competing in woodchopping.
The document is an article from the Evening Standard newspaper dated Friday 7 January 2011. It provides a brief overview of headlines and stories covered in the newspaper that day, including the Olympics countdown, Goldman Sachs being under fire for bad loans, and England cricket fans celebrating a historic Ashes series win over Australia, ending 24 years of hurt. Players and fans joined in celebration after England defeated Australia in Sydney to win the series 3-1.
The Australian cricket team was heavily criticized in Australian media for losing the Ashes series 3-1 to England. Newspapers ran harsh headlines like "Our Worst XI" and accused the team of becoming an "embarrassment of historic proportions." Commentators described the loss as "feeble and abject" and said that Australia lacks the necessary talent and depth. Former players like Shane Warne acknowledged the disappointment, saying Australia is "hurting" from not being able to regain the Ashes on home soil.
The document discusses various stress-relieving gadgets and techniques that employers are offering to employees, such as microcurrent devices that send electrical currents through the earlobes to relax the brain, breathing reminders to reduce stress and anxiety, and stress-level indicators. It also covers the growing problem of work-related stress causing health issues like burnout, and more enlightened employers providing counselling and resilience training through employee assistance programs to help manage stress.
The document discusses three travel opportunities: 1) A two-week trip to Mexico exploring Mayan culture, jungles, and beaches for £640 per person; 2) A trip to Stockholm around Christmas including flights, accommodation, and transportation for £614 per couple; 3) A bidding auction on a one-week holiday in southern France, where the highest bidder wins the week and an additional free week, with proceeds donated to charity.
This document provides travel recommendations for Sydney, Australia. It recommends taking a boat tour around the harbor like celebrity Katy Perry. It suggests staying at the Medusa hotel, a refurbished Victorian mansion, and eating at the Quay restaurant on the harbor. The document also provides details on attending the Rugby League World Cup and getting views of the city from the Sydney Harbour Bridge.
Queensland floods by Daisy Dumas, Australian Geographicdaisydumas
The document summarizes the impacts of recent flooding in southeast Queensland on local wildlife. During floods, many animals are threatened by being washed away, relocated, or drowned if they cannot swim, fly, or climb to higher ground. Tree-dwelling animals like koalas were able to survive if trees remained standing. In the aftermath, animals must find new food sources and migration routes as the landscape changes, increasing predation for some. Marine species are also affected by changes in water quality after floods. The AG Society is fundraising to track whale sharks and protect seagrass beds impacted by flood runoff.
Nendaz is a Swiss ski resort located in the Four Valleys region that is less crowded than its neighboring resort of Verbier. It has extensive ski terrain with 410km of runs served by 92 lifts across eight resorts. Nendaz offers high-quality self-catered accommodation options that are family-friendly with 80% owned by locals. It has a more relaxed atmosphere than Verbier but still offers amazing off-piste skiing opportunities like the renowned Mont Fort run, as well as night skiing events.
Peter Siddle, an Australian cricketer, almost ended his career as a child by chopping off his own finger while woodchopping. As a youth he was an accomplished woodchopper, coming in second place in competitions. Despite chopping off his finger, doctors were able to reattach it with no painkillers. On his birthday, Siddle took six wickets for Australia in the Ashes match against England, including a hat-trick, demonstrating the determination he learned as a youth competing in woodchopping.
The document is an article from the Evening Standard newspaper dated Friday 7 January 2011. It provides a brief overview of headlines and stories covered in the newspaper that day, including the Olympics countdown, Goldman Sachs being under fire for bad loans, and England cricket fans celebrating a historic Ashes series win over Australia, ending 24 years of hurt. Players and fans joined in celebration after England defeated Australia in Sydney to win the series 3-1.
The Australian cricket team was heavily criticized in Australian media for losing the Ashes series 3-1 to England. Newspapers ran harsh headlines like "Our Worst XI" and accused the team of becoming an "embarrassment of historic proportions." Commentators described the loss as "feeble and abject" and said that Australia lacks the necessary talent and depth. Former players like Shane Warne acknowledged the disappointment, saying Australia is "hurting" from not being able to regain the Ashes on home soil.
London Fashion Week brings a burst of creativity and energy to the city each September. While the catwalks showcase high fashion, the true spirit of fashion is found on the streets, where ordinary Londoners and industry observers mix together. Photographer David Yeo captures this dynamic intermingling through candid photos taken around Somerset House, revealing the diverse people that breathe life into London's fashion scene both on and off the runways.
WWOOFing allows volunteers to stay on organic farms in exchange for help with farming tasks, providing a sustainable and affordable holiday option. Switching to a renewable energy provider is an easy way to reduce reliance on fossil fuels. Growing bees at home through beekeeping has benefits like honey production and supporting declining bee populations, and can be done through beginner-friendly beehive designs.
This document summarizes how UK music festivals are addressing their environmental impacts and reducing their carbon footprints. It discusses how festivals are incentivizing public transport, charging for reusable cups, powering stages with solar panels, and increasing recycling. Glastonbury is highlighted as making strides in powering with solar, reducing on-site waste, and changing audience behaviors. While travel and waste remain challenges, festivals are engaging attendees and moving towards more sustainable practices.
National geographic article by daisy dumasdaisydumas
This document summarizes the complex issue of determining which fabrics are most environmentally friendly. It discusses the sustainability of various natural and synthetic fibers, noting that there are no simple answers and each fiber has tradeoffs. While natural materials may seem greener, heavy impacts can be associated with cotton, wool, and other natural fibers production as well. The document advocates considering the full lifecycle of garments and choosing durable materials to minimize impacts overall.
This document appears to be a series of pages from a publication about garbage and waste management. However, as the pages are blank, no meaningful summary can be generated from the content provided. The document does not contain any essential information that can be summarized in 3 sentences or less.
Tom Kevill-Davies quit his job in advertising to spend two and a half years cycling from New York to Brazil, sampling local cuisine along the way. He discovered gourmet treats in unexpected places, from Rocky Mountain oysters (bull testicles) in Montana to ceviche in Peru and acaraje (black-eyed pea fritters) in Brazil. The context, history and people behind the food became as important as the meals themselves. His favorite dish was ceviche in Iquitos, Peru, which provided relief after some inedible meals early in his journey. The trip confirmed his view that good company and context are essential to a perfect meal.
Tesco has unveiled its first designer clothing range made from recycled fabric by London eco fashion label From Somewhere. The range uses recycled, obsolete, or waste textiles that would otherwise end up in landfill. It includes figure-hugging dresses and costs between £16-£18. Marks & Spencer has announced plans to become the world's most sustainable retailer by 2015, including ensuring 50% of food, clothing, and homeware have at least one ethical element.
This document contains two short profiles of individuals working to improve the environment in London. The first profile is of Ben Ramsden, founder of Pants to Poverty, which supports organic cotton farming in India and campaigns against dangerous pesticides. The second profile is of Ed Evans, a river keeper for Thames21 who coordinates volunteers to clean up the banks of the Thames and raise awareness about reducing waste in the river.
Green London Life highlights individuals and organizations working to make London more environmentally sustainable in practical ways. Caroline Fiennes leads the campaign Global Cool, which uses celebrities to advise the public on reducing their carbon footprint through simple actions like turning down their heating while still looking stylish in warm winter clothes. Julia Craik runs Premises Studios, London's first solar-powered recording studio, demonstrating that renewable energy can power a successful business. The article also profiles several "eco-heroes" taking grassroots actions to green the city through initiatives like community gardening, local food sourcing, green roof construction, and using gardening to help those with disabilities.
Orlando Clarke, a beekeeper, plans to start a program where troubled youth ages 16-19 learn beekeeping. This will include maintaining hives and harvesting honey. He believes that working with nature can help reform offenders' behavior by teaching them discipline. The project also aims to help the declining honeybee population by placing 2,000 hives in London by 2012. Clarke hopes local boroughs will provide land for the hives, with the first location being in Peckham Rye next March.
The document summarizes the creation of an arch made of 120 wooden chairs at the Victoria and Albert Museum in London as part of the London Design Festival. The chair arch was designed by Martino Gamper based on a traditional style from the 1800s where chair arches were built in High Wycombe, Buckinghamshire to celebrate royal visits. Gamper said installing the chair arch was quite difficult due to rainy weather but that he wanted to create a "pure chair arch with no other elements" that could stand on its own through simplicity. The chair arch installation celebrates the history of British chair making and is one of many events happening during the London Design Festival through September 27th.
Jamie Oliver has released a new iPhone app called Jamie's 20-Minute Meals that includes 50 recipes that Oliver claims can each be cooked in 20 minutes. The app allows users to watch Oliver demonstrate and explain each step of a recipe through video instructions on their phone. Daisy Dumas from the Evening Standard tested the app by making a risotto recipe. She found the step-by-step instructions and pictures to be clear and easy to follow, and was able to complete the meal in the promised 20 minutes. Oliver hopes the app will help reduce takeout orders by providing quick and easy homemade meals.
Jon Alexander will attempt an ironman triathlon using environmentally friendly equipment and transportation to minimize his carbon footprint. He will bike on a bamboo bike that is light, strong, and absorbs shock well. His shoes and clothes will be made from recycled and sustainable materials like bamboo. To travel between events, he will take the Eurostar train to Paris and a night train to Barcelona, producing far fewer emissions than equivalent flights. He will eat Torq snacks and energy products to fuel his efforts.
Civil servants at the UK Department of Energy and Climate Change abandoned a trial of natural ventilation by opening windows instead of using air conditioning. They complained of noise, an uncomfortable breeze, and security concerns. An internal memo said officials decided to revert back to air conditioning for comfort reasons. Environmental groups criticized the decision, saying it sent the wrong message about reducing carbon emissions. One activist is taking matters into his own hands by teaching sewing and crocheting in public to promote self-sufficiency and address social issues.
This document summarizes a clothing collection made from recycled materials like hot air balloon fabric and Eurostar uniforms. It discusses how designer Christopher Raeburn partnered with the firm Worn Again to create jackets, bags, and other accessories from these discarded materials. A percentage of the sales will support the charity Anti-Apathy, which backs creative environmental initiatives such as sustainable fashion. The clothes can be purchased from various stores and on the Worn Again website.
David Guetta is a French DJ who lives in Paris with his family. He typically wakes up around 1 PM and picks up sushi on his way to the studio. For dinner, he often eats microwaveable meals like chicken and rice, along with pre-made salads. Though he thinks his diet is healthy, a nutritionist says it lacks fiber, fruit and vegetables. His fridge is generally stocked with yogurt, cheese and champagne.
The document summarizes an electric bicycle called the A2B that is being sold in London for nearly £2,000. It has a motor that can propel the bike up to 15mph legally without a license. It also has a "rocket boost" button that can accelerate it above 15mph for off-road use. Interviews are included with people who tried the bike and had mixed opinions on the price and usefulness for commuting in London traffic. There is also confusion about whether the boost function complies with UK laws.
Nick Weston has moved from London to live for six months in a treehouse he built himself in woods on the Kent/Sussex border. He is attempting to live as sustainably and self-sufficiently as possible, growing his own vegetables, fishing, hunting small game like rabbits and squirrels, and foraging. He has had to learn skills like hunting, skinning animals, brewing beer and cider, and building structures like a clay oven. While he misses aspects of modern life, he has appreciated how easy city living is and how much money he previously spent unnecessarily.
The document summarizes the testing of the Sonim S1 mobile phone to assess its durability. In a series of tests, the phone withstood being kicked in a parking lot with minor scratches, being run over by a car with a cracked camera lens, deep scratches from keys and tools, submersion in water and hair gel for hours with no effects, freezing overnight and working after thawing, and having boiling water poured on it with no damage. The phone survived all extreme tests intended to destroy it, demonstrating its durability and status as virtually indestructible.
Paula Radcliffe is a long-distance runner who lives in Monaco. She eats an energy bar and toast for breakfast before training for 90 minutes. When she returns home, she drinks a replenishing drink and has porridge or cereal with rice or soy milk along with a banana and toast with sardines or almond butter. In the afternoon, she eats an energy bar or biscuit before training again for an hour, and has a high-carbohydrate dinner like pasta, rice or potatoes with fish, meat and vegetables. She eats dark chocolate and fruit with yogurt or cake daily and has wine a few times a week. Her nutritionist says Radcliffe's training requires high energy intake and she gets nutrients
London Fashion Week brings a burst of creativity and energy to the city each September. While the catwalks showcase high fashion, the true spirit of fashion is found on the streets, where ordinary Londoners and industry observers mix together. Photographer David Yeo captures this dynamic intermingling through candid photos taken around Somerset House, revealing the diverse people that breathe life into London's fashion scene both on and off the runways.
WWOOFing allows volunteers to stay on organic farms in exchange for help with farming tasks, providing a sustainable and affordable holiday option. Switching to a renewable energy provider is an easy way to reduce reliance on fossil fuels. Growing bees at home through beekeeping has benefits like honey production and supporting declining bee populations, and can be done through beginner-friendly beehive designs.
This document summarizes how UK music festivals are addressing their environmental impacts and reducing their carbon footprints. It discusses how festivals are incentivizing public transport, charging for reusable cups, powering stages with solar panels, and increasing recycling. Glastonbury is highlighted as making strides in powering with solar, reducing on-site waste, and changing audience behaviors. While travel and waste remain challenges, festivals are engaging attendees and moving towards more sustainable practices.
National geographic article by daisy dumasdaisydumas
This document summarizes the complex issue of determining which fabrics are most environmentally friendly. It discusses the sustainability of various natural and synthetic fibers, noting that there are no simple answers and each fiber has tradeoffs. While natural materials may seem greener, heavy impacts can be associated with cotton, wool, and other natural fibers production as well. The document advocates considering the full lifecycle of garments and choosing durable materials to minimize impacts overall.
This document appears to be a series of pages from a publication about garbage and waste management. However, as the pages are blank, no meaningful summary can be generated from the content provided. The document does not contain any essential information that can be summarized in 3 sentences or less.
Tom Kevill-Davies quit his job in advertising to spend two and a half years cycling from New York to Brazil, sampling local cuisine along the way. He discovered gourmet treats in unexpected places, from Rocky Mountain oysters (bull testicles) in Montana to ceviche in Peru and acaraje (black-eyed pea fritters) in Brazil. The context, history and people behind the food became as important as the meals themselves. His favorite dish was ceviche in Iquitos, Peru, which provided relief after some inedible meals early in his journey. The trip confirmed his view that good company and context are essential to a perfect meal.
Tesco has unveiled its first designer clothing range made from recycled fabric by London eco fashion label From Somewhere. The range uses recycled, obsolete, or waste textiles that would otherwise end up in landfill. It includes figure-hugging dresses and costs between £16-£18. Marks & Spencer has announced plans to become the world's most sustainable retailer by 2015, including ensuring 50% of food, clothing, and homeware have at least one ethical element.
This document contains two short profiles of individuals working to improve the environment in London. The first profile is of Ben Ramsden, founder of Pants to Poverty, which supports organic cotton farming in India and campaigns against dangerous pesticides. The second profile is of Ed Evans, a river keeper for Thames21 who coordinates volunteers to clean up the banks of the Thames and raise awareness about reducing waste in the river.
Green London Life highlights individuals and organizations working to make London more environmentally sustainable in practical ways. Caroline Fiennes leads the campaign Global Cool, which uses celebrities to advise the public on reducing their carbon footprint through simple actions like turning down their heating while still looking stylish in warm winter clothes. Julia Craik runs Premises Studios, London's first solar-powered recording studio, demonstrating that renewable energy can power a successful business. The article also profiles several "eco-heroes" taking grassroots actions to green the city through initiatives like community gardening, local food sourcing, green roof construction, and using gardening to help those with disabilities.
Orlando Clarke, a beekeeper, plans to start a program where troubled youth ages 16-19 learn beekeeping. This will include maintaining hives and harvesting honey. He believes that working with nature can help reform offenders' behavior by teaching them discipline. The project also aims to help the declining honeybee population by placing 2,000 hives in London by 2012. Clarke hopes local boroughs will provide land for the hives, with the first location being in Peckham Rye next March.
The document summarizes the creation of an arch made of 120 wooden chairs at the Victoria and Albert Museum in London as part of the London Design Festival. The chair arch was designed by Martino Gamper based on a traditional style from the 1800s where chair arches were built in High Wycombe, Buckinghamshire to celebrate royal visits. Gamper said installing the chair arch was quite difficult due to rainy weather but that he wanted to create a "pure chair arch with no other elements" that could stand on its own through simplicity. The chair arch installation celebrates the history of British chair making and is one of many events happening during the London Design Festival through September 27th.
Jamie Oliver has released a new iPhone app called Jamie's 20-Minute Meals that includes 50 recipes that Oliver claims can each be cooked in 20 minutes. The app allows users to watch Oliver demonstrate and explain each step of a recipe through video instructions on their phone. Daisy Dumas from the Evening Standard tested the app by making a risotto recipe. She found the step-by-step instructions and pictures to be clear and easy to follow, and was able to complete the meal in the promised 20 minutes. Oliver hopes the app will help reduce takeout orders by providing quick and easy homemade meals.
Jon Alexander will attempt an ironman triathlon using environmentally friendly equipment and transportation to minimize his carbon footprint. He will bike on a bamboo bike that is light, strong, and absorbs shock well. His shoes and clothes will be made from recycled and sustainable materials like bamboo. To travel between events, he will take the Eurostar train to Paris and a night train to Barcelona, producing far fewer emissions than equivalent flights. He will eat Torq snacks and energy products to fuel his efforts.
Civil servants at the UK Department of Energy and Climate Change abandoned a trial of natural ventilation by opening windows instead of using air conditioning. They complained of noise, an uncomfortable breeze, and security concerns. An internal memo said officials decided to revert back to air conditioning for comfort reasons. Environmental groups criticized the decision, saying it sent the wrong message about reducing carbon emissions. One activist is taking matters into his own hands by teaching sewing and crocheting in public to promote self-sufficiency and address social issues.
This document summarizes a clothing collection made from recycled materials like hot air balloon fabric and Eurostar uniforms. It discusses how designer Christopher Raeburn partnered with the firm Worn Again to create jackets, bags, and other accessories from these discarded materials. A percentage of the sales will support the charity Anti-Apathy, which backs creative environmental initiatives such as sustainable fashion. The clothes can be purchased from various stores and on the Worn Again website.
David Guetta is a French DJ who lives in Paris with his family. He typically wakes up around 1 PM and picks up sushi on his way to the studio. For dinner, he often eats microwaveable meals like chicken and rice, along with pre-made salads. Though he thinks his diet is healthy, a nutritionist says it lacks fiber, fruit and vegetables. His fridge is generally stocked with yogurt, cheese and champagne.
The document summarizes an electric bicycle called the A2B that is being sold in London for nearly £2,000. It has a motor that can propel the bike up to 15mph legally without a license. It also has a "rocket boost" button that can accelerate it above 15mph for off-road use. Interviews are included with people who tried the bike and had mixed opinions on the price and usefulness for commuting in London traffic. There is also confusion about whether the boost function complies with UK laws.
Nick Weston has moved from London to live for six months in a treehouse he built himself in woods on the Kent/Sussex border. He is attempting to live as sustainably and self-sufficiently as possible, growing his own vegetables, fishing, hunting small game like rabbits and squirrels, and foraging. He has had to learn skills like hunting, skinning animals, brewing beer and cider, and building structures like a clay oven. While he misses aspects of modern life, he has appreciated how easy city living is and how much money he previously spent unnecessarily.
The document summarizes the testing of the Sonim S1 mobile phone to assess its durability. In a series of tests, the phone withstood being kicked in a parking lot with minor scratches, being run over by a car with a cracked camera lens, deep scratches from keys and tools, submersion in water and hair gel for hours with no effects, freezing overnight and working after thawing, and having boiling water poured on it with no damage. The phone survived all extreme tests intended to destroy it, demonstrating its durability and status as virtually indestructible.
Paula Radcliffe is a long-distance runner who lives in Monaco. She eats an energy bar and toast for breakfast before training for 90 minutes. When she returns home, she drinks a replenishing drink and has porridge or cereal with rice or soy milk along with a banana and toast with sardines or almond butter. In the afternoon, she eats an energy bar or biscuit before training again for an hour, and has a high-carbohydrate dinner like pasta, rice or potatoes with fish, meat and vegetables. She eats dark chocolate and fruit with yogurt or cake daily and has wine a few times a week. Her nutritionist says Radcliffe's training requires high energy intake and she gets nutrients
Muktapishti is a traditional Ayurvedic preparation made from Shoditha Mukta (Purified Pearl), is believed to help regulate thyroid function and reduce symptoms of hyperthyroidism due to its cooling and balancing properties. Clinical evidence on its efficacy remains limited, necessitating further research to validate its therapeutic benefits.
Adhd Medication Shortage Uk - trinexpharmacy.comreignlana06
The UK is currently facing a Adhd Medication Shortage Uk, which has left many patients and their families grappling with uncertainty and frustration. ADHD, or Attention Deficit Hyperactivity Disorder, is a chronic condition that requires consistent medication to manage effectively. This shortage has highlighted the critical role these medications play in the daily lives of those affected by ADHD. Contact : +1 (747) 209 – 3649 E-mail : sales@trinexpharmacy.com
Histololgy of Female Reproductive System.pptxAyeshaZaid1
Dive into an in-depth exploration of the histological structure of female reproductive system with this comprehensive lecture. Presented by Dr. Ayesha Irfan, Assistant Professor of Anatomy, this presentation covers the Gross anatomy and functional histology of the female reproductive organs. Ideal for students, educators, and anyone interested in medical science, this lecture provides clear explanations, detailed diagrams, and valuable insights into female reproductive system. Enhance your knowledge and understanding of this essential aspect of human biology.
Here is the updated list of Top Best Ayurvedic medicine for Gas and Indigestion and those are Gas-O-Go Syp for Dyspepsia | Lavizyme Syrup for Acidity | Yumzyme Hepatoprotective Capsules etc
Local Advanced Lung Cancer: Artificial Intelligence, Synergetics, Complex Sys...Oleg Kshivets
Overall life span (LS) was 1671.7±1721.6 days and cumulative 5YS reached 62.4%, 10 years – 50.4%, 20 years – 44.6%. 94 LCP lived more than 5 years without cancer (LS=2958.6±1723.6 days), 22 – more than 10 years (LS=5571±1841.8 days). 67 LCP died because of LC (LS=471.9±344 days). AT significantly improved 5YS (68% vs. 53.7%) (P=0.028 by log-rank test). Cox modeling displayed that 5YS of LCP significantly depended on: N0-N12, T3-4, blood cell circuit, cell ratio factors (ratio between cancer cells-CC and blood cells subpopulations), LC cell dynamics, recalcification time, heparin tolerance, prothrombin index, protein, AT, procedure type (P=0.000-0.031). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and N0-12 (rank=1), thrombocytes/CC (rank=2), segmented neutrophils/CC (3), eosinophils/CC (4), erythrocytes/CC (5), healthy cells/CC (6), lymphocytes/CC (7), stick neutrophils/CC (8), leucocytes/CC (9), monocytes/CC (10). Correct prediction of 5YS was 100% by neural networks computing (error=0.000; area under ROC curve=1.0).
Cell Therapy Expansion and Challenges in Autoimmune DiseaseHealth Advances
There is increasing confidence that cell therapies will soon play a role in the treatment of autoimmune disorders, but the extent of this impact remains to be seen. Early readouts on autologous CAR-Ts in lupus are encouraging, but manufacturing and cost limitations are likely to restrict access to highly refractory patients. Allogeneic CAR-Ts have the potential to broaden access to earlier lines of treatment due to their inherent cost benefits, however they will need to demonstrate comparable or improved efficacy to established modalities.
In addition to infrastructure and capacity constraints, CAR-Ts face a very different risk-benefit dynamic in autoimmune compared to oncology, highlighting the need for tolerable therapies with low adverse event risk. CAR-NK and Treg-based therapies are also being developed in certain autoimmune disorders and may demonstrate favorable safety profiles. Several novel non-cell therapies such as bispecific antibodies, nanobodies, and RNAi drugs, may also offer future alternative competitive solutions with variable value propositions.
Widespread adoption of cell therapies will not only require strong efficacy and safety data, but also adapted pricing and access strategies. At oncology-based price points, CAR-Ts are unlikely to achieve broad market access in autoimmune disorders, with eligible patient populations that are potentially orders of magnitude greater than the number of currently addressable cancer patients. Developers have made strides towards reducing cell therapy COGS while improving manufacturing efficiency, but payors will inevitably restrict access until more sustainable pricing is achieved.
Despite these headwinds, industry leaders and investors remain confident that cell therapies are poised to address significant unmet need in patients suffering from autoimmune disorders. However, the extent of this impact on the treatment landscape remains to be seen, as the industry rapidly approaches an inflection point.
Promoting Wellbeing - Applied Social Psychology - Psychology SuperNotesPsychoTech Services
A proprietary approach developed by bringing together the best of learning theories from Psychology, design principles from the world of visualization, and pedagogical methods from over a decade of training experience, that enables you to: Learn better, faster!
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
Dehradun #ℂall #gIRLS Oyo Hotel 8107221448 #ℂall #gIRL in Dehradun
Stress2
1. evening standard Wednesday 18 november 2009 H 29
Health & Beauty
o relieve the pressure verdict of the stress thermometers. On but not as a substitute for physio/
Six office StreSS tipS
eat dark chocolate
Chocolate contains theobromine,
which has a similar effect to caffeine
but also magnesium which is calming.
Swiss scientists say a small chunk of
Calming influence: deadline? Cold. Breaking news stories? osteopathy. dark chocolate a day can reduce levels
Sophie Goodchild Cold. Slagging off X Factor with cost/contact: £39.99/www. of cortisol — the stress hormone.
tests the Emwave, colleagues? Cold. I don’t think I’m as theyantramat.co.uk
a Walkman-like stressed as all that. oliver Wadeson Be screen-saved
gadget that cost: £2 for traditional thermometer At meditainment.com you can watch
monitors your or £7.99 for 36 stress squares/www. eMWave three-minute de-stress videos or
breathing hypnosishealthcare.com how it works: This Walkman-like download soundtracks. “You take
Jim armitage gadget monitors your breathing and three minutes out and when you come
trains you to be less reactive and think back, stress is greatly reduced,” says
yantra Mat more clearly. You switch Richard Latham, Meditainment’s
how it works: The fabric mat is it on, put your thumb on scriptwriter, who believes desktop
covered with discs of plastic the sensor button then backgrounds or screensavers that
“spikes” like a modern version start breathing in and out display calming scenery can also help.
of the bed-of-nails. When you in time with the blue light
rest any part of the body on display. get a lighter life
the contact points, the mat any science? The A lack of natural daylight can make us
distributes your weight breathing “pacer” facility feel low and lethargic, cutting
evenly, creating a feeling of on the emwave productivity and adding to stress
almost-instant relaxation. synchronises to your heart levels. Dr Victoria Revell, a scientist at
any science? Based on rhythms. Slowing yourself the University of Surrey says: “Brain
ancient Chinese principles of down reduces anxiety and scans show that better light improves
acupressure. The contact increases well-being by levels of alertness.” Try the Lumie
points prompt the body to suppressing your urge to Desklamp or the Lumie Zip.
release endorphins and oxytocin. These panic in stressful situations. (£129/£125 www.lumie.com)
are the body’s pain-relieving and relax factor: This gadget was a bit
happiness hormones. alarming at first. When I switched it Manage your Manager
relax factor: The sharp contact points on for a session, red lights started Manage Your Boss (Prentice, £7.50) is
did cause an initial prickly feeling. Once flashing then blue. The idea is to train Jay Ros’s definitive guide to getting
I got used to the sensation, the mat was yourself to get in the zone of “high the right relationship with your boss.
surprisingly comfortable. No real coherence”. I found myself juggling Ros tells us that not only are bosses
“wow” factor but does induce sense of breathing deeply with meeting human but they have a huge impact
calm throughout body. For sufferers of deadlines. Think with more practice on your job satisfaction.
lower back pain caused by stress like would be useful. and being reminded
myself, the Yantra mat will prove a to breathe is definitely a bonus. tap to tranquillize
useful additional tool to loosen muscles cost/contact: £125/www.relax-uk.com Paul McKenna shows people how to get
around problematic areas of the back sophie goodchild rid of cravings by tapping points on
their faces and bodies and it works for
stress, too. The technique, developed
StreSS factS and figureS by Dr Roger Callahan, is called thought
field therapy (TFT) and involves
Most stressed professions london facts completing a sequence of taps and
(percentage suffering from severe and ■ 96,800 cases of anxiety or repeating if necessary. Find out more
extreme stress levels) depression-related illness last year. at www.rogercallahan.com .
Lawyers 38% ■ 1.6 million working days lost as a
Bankers and financiers 28.4% result of illness including that related to plant your proBleMs
Doctors and nurses 27.7% job anxiety. A Nasa scientist found desk plants can
Teachers 23.6% ■ 617,520 Londoners complain their job reduce sick building syndrome,
is “extremely stressful”. Norwegian studies show in a workplace
professionals who can’t switch off ■ £4 billion a year loss to society and with plants common illnesses fall by
Estate agents/property developers 52% economy as a result of work-related 30-45 per cent, and psychologists
Lawyers 51% illness. believe that plants make employees
rebecca reid
Teachers 46% ■ £20,000 to £30,000 is the usual more productive. The message is clear
Actors/performers 41.9% compensation for stress-related — go green in the office.
Charity workers 41.7% “injury”.
many causes, many symptoms HOW ON THE VERGE ARE YOU?
try this stress quiz to find out. Just answer yes or no to the questions
W
e all need a certain
amount of pressure in Dr Christian low self-esteem and forgetfulness. It
can even lower your sex drive. 1. Do you feel angry or irritable much of 13. Do you suffer from breathlessness?
our lives to make our
work satisfying and
Jessen Finally, behavioural symptoms can
cause sufferers to becoming irritable,
the time?
2. Do you have dramatic mood swings?
14. Do you suffer from frequent
indigestion, constipation or diarrhoea?
help us meet our aggressive and withdrawn, and to stop 3. Do you suffer from obsessive thoughts 15. Do you experience muscle twitches?
deadlines. But too much pressure communicating. an affected person or actions, such as repeated handwashing 16. Do you feel constantly worn out?
without having the chance to let off vital signs may show signs of changes in eating or constantly checking whether you have 17. Do you suffer from pains in the chest
steam causes stress. Of course, what is and sleeping patterns; they may drink left the gas on? or tightness?
stressful for one person may not be and smoke more, and even start 4. Do you often feel apprehensive or 18. Do you suffer from palpitations or a
stressful for another. Some thrive on it to divide these into physiological, excessively self-medicating. Of course, frightened? “lump” in the throat or stomach?
while others crumble. psychological and behavioural these will also affect home life, making 5. Do you suffer from diminished libido? 19. Are you too busy to relax?
If you feel that you are always symptoms. them more “difficult” outside work, 6. Do you have feelings of self-loathing or 20. Do you stick rigidly to routines?
rushing about, trying to be in too Physiological symptoms caused by less able to cope with their family and lack of self-worth?
many places at once, missing meal stress include headaches, migraines, maybe even neglecting their hygiene 7. Do you have suicidal thoughts? If you have answered “yes” to three or
breaks, for ever taking work home stomach disorders, raised blood and personal appearance. 8. Do you find yourself unable to more of these questions, it is likely that
with you, and never seem to have pressure, changing sleep patterns, There is rarely any one single cause concentrate? you may be heading for the tipping point.
enough time for exercise, relaxation muscle spasms, back/shoulder/neck of work-related stress. While sudden, 9. Do you feel constantly guilty? Prolonged anxiety and stress can lead to
or spending time with your family, pain, general malaise and an unexpected pressures can trigger it, it 10. Do you experience feelings of potentially major health problems such as
then you may well be at risk of unwillingness to work. is often the result of a range of stressful paranoia? heart disease, hypertension or high blood
developing stress-related problems. Psychological symptoms can cause factors that build up over time. If they 11. Do you get aches in your back and pressure. Now is the time to contact your
Stress is caused by a wide variety of you to grow resentful towards your are left undetected and untreated, shoulders? GP to discuss your health and think about
different situations, and so can also work, making it a place of anxiety, they can reach boiling point and cause 12. Do you suffer from insomnia, changes you can make to your lifestyle to
have a wide range of symptoms. I tend tension and the cause of irritability, a full mental breakdown. nightmares or wake up still feeling tired? ease pressure.