In short; the propaganda per se; is not bad. But the slavery of propaganda in preference to or at the cost of pursuit of excellence; has definitely given rise to stress in all the walks of life.
NAMA is a word used to indicate true self; inseparable from the unifying universal self. Hence forgetting our self or being oblivious to our self can be referred to as NAMAVISMARAN [NAMA (self); VISMARAN (forgetting)].
As we “forget” our true self (NAMAVISMARAN), i.e. undergo a “descent” into our caricatures, we begin to live as our caricatures. We then get segregated into races, philosophies, ideologies, religions, cultures, nations, regions, families and individuals! Latter we descend further by the downward momentum of individualization and into pettier and meaner life!
This is because; our physical, mental, intellectual and financial involvement in this activity; as a service to Guru; is still superficial. As our involvement goes on increasing and as the mega process of NAMASMARAN begins to reach, where it is unknown; we would begin to get the satisfaction of service to Guru or devotion to Guru i.e. Guru bhakti.
NAME, NAMASMARAN and TOTAL STRESS MANAGEMENT: The concept of the title is; NAMA is the absolute truth beyond time and space. It is the ultimate controlling center. NAMASMARAN is the product of NAMA; and TOTAL STRESS MANAGEMENT is the effect of NAMASMARAN.
But those; working towards the welfare of mankind; seem to lack this force, fervor, frenzy, courage of conviction, unity and dedication. They hesitate to spend even pittance and take even minor most risk! Can NAMASMARAN consolidate, boost, and empower us; to work with force, courage, conviction, unity and dedication; towards; blossoming of one and all; so that we can conquer the STRESS of sectarian bigotry and fanaticism? We have to verify by practice!
NAME, NAMASMARAN and TOTAL STRESS MANAGEMENT: The concept of the title is; NAMA is the absolute truth beyond time and space. It is the ultimate controlling center. NAMASMARAN is the product of NAMA; and TOTAL STRESS MANAGEMENT is the effect of NAMASMARAN.
NAMA is a word used to indicate true self; inseparable from the unifying universal self. Hence forgetting our self or being oblivious to our self can be referred to as NAMAVISMARAN [NAMA (self); VISMARAN (forgetting)].
As we “forget” our true self (NAMAVISMARAN), i.e. undergo a “descent” into our caricatures, we begin to live as our caricatures. We then get segregated into races, philosophies, ideologies, religions, cultures, nations, regions, families and individuals! Latter we descend further by the downward momentum of individualization and into pettier and meaner life!
This is because; our physical, mental, intellectual and financial involvement in this activity; as a service to Guru; is still superficial. As our involvement goes on increasing and as the mega process of NAMASMARAN begins to reach, where it is unknown; we would begin to get the satisfaction of service to Guru or devotion to Guru i.e. Guru bhakti.
NAME, NAMASMARAN and TOTAL STRESS MANAGEMENT: The concept of the title is; NAMA is the absolute truth beyond time and space. It is the ultimate controlling center. NAMASMARAN is the product of NAMA; and TOTAL STRESS MANAGEMENT is the effect of NAMASMARAN.
But those; working towards the welfare of mankind; seem to lack this force, fervor, frenzy, courage of conviction, unity and dedication. They hesitate to spend even pittance and take even minor most risk! Can NAMASMARAN consolidate, boost, and empower us; to work with force, courage, conviction, unity and dedication; towards; blossoming of one and all; so that we can conquer the STRESS of sectarian bigotry and fanaticism? We have to verify by practice!
NAME, NAMASMARAN and TOTAL STRESS MANAGEMENT: The concept of the title is; NAMA is the absolute truth beyond time and space. It is the ultimate controlling center. NAMASMARAN is the product of NAMA; and TOTAL STRESS MANAGEMENT is the effect of NAMASMARAN.
NAME, NAMASMARAN and TOTAL STRESS MANAGEMENT: The concept of the title is; NAMA is the absolute truth beyond time and space. It is the ultimate controlling center. NAMASMARAN is the product of NAMA; and TOTAL STRESS MANAGEMENT is the effect of NAMASMARAN.
For me; NAMASMARAN is a straight forward and transcientific process of individual and universal blossoming, which may be termed simply as “holistic evolution” to distinguish it from “organic evolution”. Hence my Guru says that practice of NAMASMARAN is for the sake of NAMASMARAN only!
NAME, NAMASMARAN and TOTAL STRESS MANAGEMENT: The concept of the title is; NAMA is the absolute truth beyond time and space. It is the ultimate controlling center. NAMASMARAN is the product of NAMA; and TOTAL STRESS MANAGEMENT is the effect of NAMASMARAN.
NAME, NAMASMARAN and TOTAL STRESS MANAGEMENT: The concept of the title is; NAMA is the absolute truth beyond time and space. It is the ultimate controlling center. NAMASMARAN is the product of NAMA; and TOTAL STRESS MANAGEMENT is the effect of NAMASMARAN.
Student: But how to surrender? Every time I think of surrendering; I feel that I am being submissive to something imaginary. I feel that I am becoming paranoid. Why is this so?
A person is called degenerate and dead when his or her conscience is dead. A true disease of an individual; is his or her trivialization or vulgarization. This happens when he or she gets disoriented and lost from his or her true self. Gita enlightens and empowers us; to annihilate this true death! Gita never dwells on any ideology, religion, race, region, nation, cult or a sect; but catalyzes our ascent; to our immortal and blissful true (universal) self, the greatest and ultimate goal; we can ever aspire for!
However; the greatest miracle of NAMASMARAN is that through such easily identifiable “miracles” and through unidentifiable “miraculous grace” that springs from Guru; we get relieved from the bondage and burden of our urges, missions, rationality, hypotheses and anticipations and the associated vain glory or frustration; in short; ego! This is the beginning of true victory and true surrender, and takes us closer to the lotus feet of Guru! Truly this is the individual blossoming; and is inseparable from the universal blossoming!
STRESS OF ILLNES:
Actually, we have immeasurable and infinite storehouse of vitality inside us, which is not described or highlighted in media and this immense storehouse of globally benevolent potential within us escapes our own attention also; and we assume ourselves to be fickle, frail and fragile.
Today we have internet, mobile phones and video conferencing and other speedy means to connect and meet physically. But chat, gossip, flattery, accolades etc; may elevate the mood temporarily and superficially; but cannot reach the soul and cannot accomplish heart to heart communication. Lack of satisfactory communication is a major cause of stress.
NAME, NAMASMARAN and TOTAL STRESS MANAGEMENT: The concept of the title is; NAMA is the absolute truth beyond time and space. It is the ultimate controlling center. NAMASMARAN is the product of NAMA; and TOTAL STRESS MANAGEMENT is the effect of NAMASMARAN.
For me; NAMASMARAN is a straight forward and transcientific process of individual and universal blossoming, which may be termed simply as “holistic evolution” to distinguish it from “organic evolution”. Hence my Guru says that practice of NAMASMARAN is for the sake of NAMASMARAN only!
NAME, NAMASMARAN and TOTAL STRESS MANAGEMENT: The concept of the title is; NAMA is the absolute truth beyond time and space. It is the ultimate controlling center. NAMASMARAN is the product of NAMA; and TOTAL STRESS MANAGEMENT is the effect of NAMASMARAN.
NAME, NAMASMARAN and TOTAL STRESS MANAGEMENT: The concept of the title is; NAMA is the absolute truth beyond time and space. It is the ultimate controlling center. NAMASMARAN is the product of NAMA; and TOTAL STRESS MANAGEMENT is the effect of NAMASMARAN.
Student: But how to surrender? Every time I think of surrendering; I feel that I am being submissive to something imaginary. I feel that I am becoming paranoid. Why is this so?
A person is called degenerate and dead when his or her conscience is dead. A true disease of an individual; is his or her trivialization or vulgarization. This happens when he or she gets disoriented and lost from his or her true self. Gita enlightens and empowers us; to annihilate this true death! Gita never dwells on any ideology, religion, race, region, nation, cult or a sect; but catalyzes our ascent; to our immortal and blissful true (universal) self, the greatest and ultimate goal; we can ever aspire for!
However; the greatest miracle of NAMASMARAN is that through such easily identifiable “miracles” and through unidentifiable “miraculous grace” that springs from Guru; we get relieved from the bondage and burden of our urges, missions, rationality, hypotheses and anticipations and the associated vain glory or frustration; in short; ego! This is the beginning of true victory and true surrender, and takes us closer to the lotus feet of Guru! Truly this is the individual blossoming; and is inseparable from the universal blossoming!
STRESS OF ILLNES:
Actually, we have immeasurable and infinite storehouse of vitality inside us, which is not described or highlighted in media and this immense storehouse of globally benevolent potential within us escapes our own attention also; and we assume ourselves to be fickle, frail and fragile.
Today we have internet, mobile phones and video conferencing and other speedy means to connect and meet physically. But chat, gossip, flattery, accolades etc; may elevate the mood temporarily and superficially; but cannot reach the soul and cannot accomplish heart to heart communication. Lack of satisfactory communication is a major cause of stress.
समाजात; आणि विशेषत: सर्व प्रकारच्या सत्ताकेंद्रांत जेवढे नामस्मरण वाढेल, तेवढ्या अधिकाधिक प्रमाणात समाजामधील सर्व स्तरांवरील क्रिया आणि प्रतिक्रिया अधिकाधिक पूर्वग्रहरहित (न्यायपूर्ण) आणि म्हणून कल्याणकारक होतात आणि व्यक्ती आणि समाजाचा सर्वांगीण विकास वेगाने होऊ लागतो.
ज्याप्रमाणे चुलीमुळे आग नियंत्रित होते आणि तिची धग भांड्याला नीटपणे लागून अन्न वेळेमध्ये शिजते, त्याचप्रमाणे जीवनातील सर्व भोगांची आणि उपभोगांची धग नामस्मरणरुपी चुलीमुळे अंतरात्म्याकडे पोचते आणि अंतरात्म्यामध्ये समाधानरुपी अन्न शिजू लागते. साहजिकच आपले, आपल्या कुटुंबियांचे आणि समाजाचे समाधान होऊ लागते! ज्याप्रमाणे चुली आणि त्यांच्यातील आग कमी जास्त असते, त्याचप्रमाणे नामसाधकांच्या प्रगतीचे टप्पे देखील वेगवेगळे असतात. पण नामस्मरणाने समाधानाकडे वाटचाल होऊ लागते; हे केवळ सद्गुरू ब्रह्मचैतन्य श्री गोंदवलेकर महाराजांच्याच नव्हे तर सर्वच संत महात्म्यांच्या शिकवणीचे त्रिवार सत्य असे सार आहे.
ह्या अमृताचा अगदी अंशत: अनुभव देखील जीवन झळाळून टाकणारा असतो आणि तो येण्यासाठी चित्तशुद्धी होत राहण्याची आवश्यकता असते. ही चित्तशुद्धी नामस्मरणाद्वारे होत जाते आणि ती चित्तशुद्धी देखील कोणत्याही बाह्य लक्षणाने ओळखता येत नाही आणि दाखविता येत नाही!
नामसंकल्पयुक्त नामस्मरणाचे चैतन्याधिष्ठान आणि सद्गुरुंची गोड ओढ; यानी रटाळ क्षण उत्साहवर्धक बनतो, कंटाळवाणा दिवस सण बनतो आणि निरर्थक आयुष्य कृतार्थ बनते! कुणीही हे करून पाहिले तर याचा अनुभव येऊ शकेल.
होय! अशी एक पायाभूत सुविधा आहे! पूर्णपणे बिनखर्चाची, कुणाचेही अंत:करण आणि आणि अस्मिता न दुखावणारी आणि सर्वांनाच सहज शक्य अशी ही सुविधा आहे. ह्या सुविधेद्वारे सद्विचार, सद्भावना, सद्वासना, सत्संकल्प आणि विश्वकल्याणकारी आणि सतत विकसित होणारी सत्कार्ये अविरतपणे घडू लागतात. प्रत्येक व्यक्ती समाधानी आणि कृतार्थ होऊ लागते. अशी अत्याधिक अत्यावश्यक पायाभूत सुविधा म्हणजे नामस्मरण
“नाम घेणाऱ्याला सत्कर्म टाळू म्हणता टाळता येत नाही” असे जेव्हां सद्गुरू श्री. ब्रह्मचैतन्य महाराज गोंदवलेकर म्हणतात, तेव्हां त्यांमध्ये वरील सर्वकाही अंतर्भूत आहे, म्हणजेच वेळ, पैसा आणि शक्ती यांचे (अर्थात आयुष्याचे) सर्वोत्तम व्यवस्थापन अनुस्यूत आहे!
परंतु पूर्वजन्मीच्या किंवा ह्या जन्मीच्या नामस्मरणाने; स्वत:च्या आणि इतरांच्या कल्याणाविषयी जी वैचारिक स्पष्टता येते ती स्पष्टता, जी गोड आणि उत्कट आस्था तयार होते ती आस्था, आणि त्या अनुरोधाने जी मन:पूर्वक कृती घडते ती कृती; ह्या तीनही बाबी मात्र हृदयाच्या अगदी जवळ असतात.
१. केवळ वाचन आणि चर्चेने नामस्मरणाच्या ह्या विश्वकल्याणकारी सामर्थ्याची संकल्पना काही प्रमाणात येऊ शकेल, पण त्याची प्रचीती येण्यासाठी नामस्मरण करणेच अत्यावश्यक आहे. किंबहुना, नामस्मरणाला पर्याय नाही असे म्हटले तरी ते अतिशयोक्त ठरणार नाही!
आपणा सर्वांना निकोप जीवनासाठी आणि जीवनाच्या सार्थकतेसाठी नामस्मरणाची, श्रीक्षेत्र गोंदवल्याची आणि अश्या प्रसाद व महाप्रसादाची अत्यंत तीव्र आणि निकडीची गरज आहे!
नामस्मरण करत प्रसाद किंवा महाप्रसाद वाढणारे आणि ग्रहण करणारे सर्वच जण ईश्वराप्रती किंवा आपल्या सद्गुरुप्रती कृतज्ञ असतात आणि कृतार्थ असतात! यातून परस्परांच्या कल्याणाची सद्वासना, सद्भावना, सद्विचार, आणि सत्संकल्प यांचे पोषण होऊन सर्वांचे उत्थान अधिक जोमाने गतिमान होते.
सद्गुरू श्री. ब्रह्मचैतन्य गोंदवलेकर महाराज म्हणतात, "आंधळ्याने पाणी भरावे तसे नाम घ्यावे. भांडे भरले किती आणि रिकामे किती, हे त्याला समजत नाही. तो भरतच राहतो. तसे नाम सतत घेत राहावे. देहाच्या कणाकणातून नामाचा ध्वनी केव्हाही यावा इतके नाम घ्यावे. सुरुवातीला रामनाम असे मुरले की पुन्हा जास्त लक्ष द्यावे लागत नाही. आपोआप देहाचे सारे कण नामजप करतात."
आम्ही सर्वच माध्यमवाल्यांनी नामस्मरणाचा अत्यंत आस्थेने अभ्यास, अगत्यपूर्वक अंगिकार आणि जीव तोडून प्रसार केला पाहिजे ह्याची खोलवर आणि तीव्र जाणीव झाली आणि त्यातच आमचे आणि सर्वांचे भले आहे ह्याबद्दल खात्री झाली!!
तुमची परम कृपा मात्र प्राणवायूप्रमाणे चिरंतन, चैतन्यमय, स्फूर्तिदायी आणि शाश्वत समाधान देणारी आहे! नामस्मरणाच्या आणि तज्जन्य सद्बुद्धीच्या, सद्भावनांच्या, सद्वासनांच्या, सत्संकल्पांच्या आणि सत्कर्माच्या रूपाने ती माझ्यासारख्या सर्वांना उपलब्ध झाली आहे!
श्रीराम समर्थ!
सतत नामस्मरण घडू लागले, गुरुची सत्ता पदोपदी जाणवू लागली, गुरुचे सानिध्य क्षणोक्षणी जाणवू लागले, जगण्याची उमेद वाढली, आजारपणाची आणि मृत्त्युची भीती गेली; आणि विशेष म्हणजे; ह्यापेक्षा वेगळे ध्येय गाठण्याची व त्यासाठी अधिक काही करण्याची उर्मी गेली तर तोच साक्षात्कार नाही का?
ह्यामुळे आहे त्या परिस्थितीत नामस्मरण टिकू लागते आणि वाढू लागते! आश्चर्याची बाब म्हणजे आपल्या लक्षात येऊ लागते की हीच ती खरी शांतता, खरी विश्रांती आणि हीच ती (स्वत:, इतर आणि परिस्थिती यांच्यामधल्या) खऱ्या सुधारणेची ईश्वरी प्रक्रिया!
Our Sadguru Shri Brahmachaitanya Maharaj Gondavalekar said, “Trust that the practice of NAMASMARAN as prescribed by Guru would emancipate the universe! Lord Rama would bless!”
नामाच्या सत्तेनेच आपल्या कळत-नकळत; सदभिरुची, सदिच्छा, सत्संकल्प, सत्प्रेरणा, सत्बुद्धी, सद्भावना, सद्वासना, सदाचार; म्हणजेच सद्गुरू ब्रह्मचैतन्य श्री. गोंदवलेकर महाराजांना अभिप्रेत असलेली संस्कृती आणि सुधारणा; व्यक्तिगत आणि सामाजिक जीवनात अधिकाधिक प्रमाणात आविष्कृत होत असतात!
पण काळजी करण्याचे कारण नाही. आपल्या इच्छे-अनिच्छेपलिकडे; विश्वचैतन्याची जननी आपली गुरुमाउली सर्व बऱ्या वाईट प्रसंगात आपल्याला सांभाळून आपल्याला चैतन्यामृतपान करवीत आहे. आपल्याकडून नामस्मरण आणि स्वधर्मपालन वाढत्या प्रमाणात करवीत आहे. सदभिरुची, सदिच्छा, सत्संकल्प, सत्प्रेरणा, सत्बुद्धी, सद्भावना, सद्वासना, सदाचार यांनी आपले व्यक्तिगत आणि सामाजिक जीवन अधिकाधिक प्रमाणात भरून टाकीत आहे! नामस्मरण करता करता आपल्याला नक्कीच याचा अनुभव येतो!
पण; काळजी करण्याचे कारण नाही. आपल्या इच्छे-अनिच्छेपलिकडे; विश्वचैतन्याची जननी आपली गुरुमाउली सर्व बऱ्या वाईट प्रसंगात आपल्याला सांभाळून आपल्याला चैतन्यामृतपान करवीत आहे. आपल्याकडून नामस्मरण आणि स्वधर्मपालन वाढत्या प्रमाणात करवीत आहे. सदभिरुची, सदिच्छा, सत्संकल्प, सत्प्रेरणा, सत्बुद्धी, सद्भावना, सद्वासना, सदाचार यांनी आपले व्यक्तिगत आणि सामाजिक जीवन अधिकाधिक प्रमाणात भरून टाकीत आहे! नामस्मरण करता करता आपल्याला नक्कीच याचा अनुभव येतो!
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...
Stress and propaganda dr. shriniwas kashalikar
1. STRESS
AND
PROPGAGANDA
DR.
SHRINIWAS
KASHALIKAR
2. There are many causes of STRESS. But in party
politics, power games, entertainment, showbiz,
performing arts, commercial art, writing, publishing,
advertising, marketing and such businesses; the major
cause of STRESS; is the insatiable and unending craze
of propaganda (due to the dread of being ignored,
neglected and dejected).
Even the “erudite, wise and spiritual” people amongst
us; have fallen prey to propaganda and feel terribly
handicapped, and at a major loss; in absence of
propaganda!
Being cut off from our own selves and from the innate
core of others; has made us caricatures of our selves. We
have become unsatisfied and diffident about our
convictions. Hence; if we get material success; then we
become delirious and arrogant; and if we fail, then we
become fragile and frustrated. But in both cases we are
weak and starved of devoid of inner fulfillment. We are
dependent on the crutches of propaganda for our
survival!
Thus instead of capturing the excellence in our fields;
we have become slaves and prisoners of bombastic
3. banners, hollow hoardings, pitiable placards,
preposterous posters, scandalous slogans and the deluge
of cheap advertisements in print and electronic media
and bloat with unfathomable pride and arrogance!
In short; the propaganda per se; is not bad. But the
slavery of propaganda in preference to or at the cost of
pursuit of excellence has definitely given rise to stress in
all the walks of life.
In turn; the cancerous growth of this unproductive
business of propaganda; that represents few elites in the
society is flourishing at the cost of productive majority.
Such other businesses include commission agents,
bureaucracy etc; and are pivotal in
causing/precipitating the global growth of mercenary
tendencies on the one hand; and dwindling buying
capacity in the productive masses on the other; leading
to global recession!
We have to understand that addiction of propaganda is
as bad as any other addiction if not worse and not only
does it handicap us; but it degenerates and perverts us!
4. This addiction is like accepting the mastery of our own
caricature or our shadow and meekly following it!
We still have a chance and a choice; to either become
slaves of the propaganda; and spread our STRESS; or
become free from such slavery and STRESS; through
the pursuit of excellence in fields; by way of study and
practice of holistic perspective, thinking, motivation and
actions. This is Total Stress Management (the core of
which is NAMASMARAN).
BUT WHAT IS NAMASMARAN?
Namasmaran usually embodies; remembering the name
of God, Guru, great souls; such as prophets and
whatever is considered as holy e.g. planets and stars. It
is remembered silently, loudly, along with music, dance,
along with breathing, in group or alone. Further,
NAMASMARAN is either counted by some means such
as fingers, rosary (called SMARANI or JAPAMALA),
or electronic counter; or practiced without counting.
The traditions vary from region to region and from
religion to religion.
However the universal principle underlying
5. NAMASMARAN is to reorient our physiological and
social being; with our true self and establish and
strengthen the bond between; our physiological and
social being; with our true self; and finally reunification
or merger with our true self!
Since individual consciousness is the culmination of
every activity in life; and NAMASMARAN the pinnacle
of or culmination of individual consciousness;
NAMASMARAN is actually opening the final common
pathway to objective or cosmic consciousness; so that
individual consciousness in every possible activity gets
funneled into or unified with Him (our true self)!
Thus NAMASMARAN is in fact the YOGA of YOGA in
the sense that it is the culmination of consciousness
associated with every possible procedure and technique
in the yoga that we are familiar with. It is the
YOGA of YOGA because it is the culmination of
consciousness associated with all the activities in the
universe, which it encompasses as well! It is YOGA of
YOGA because everybody in the world irrespective of
his/her tradition and the beliefs; would eventually,
ultimately and naturally reach it; in the process of
liberation. Even so called non believers also would not
6. “miss” the “benefit of NAMASMARAN as they may
remember true self through one symbol or another”!
Just as NAMASMARAN is YOGA of YOGA it is
meditation of meditation also! This is because the
natural and ultimate climax of every form of
meditation; is remembering true self or merging with
cosmic consciousness effortlessly!
These facts however have to be realized with persistent
practice of NAMSMARAN and not blindly believed or
blindly disbelieved with casual approach!
In short NAMSMARAN is super-bounty of cosmic
consciousness for every individual to realize it (cosmic
consciousness)! This is truly a super-bounty because a
person, who experiences it, rises above mercenary,
commercial and even professional and charity planes
and manifest super- transactions in his or her life!
These are just few observations to give rough idea about
what is NAMASMARAN. NAMASMARAN is an ocean
of bliss. Its true meaning is beyond description in words
and has to b experienced, not by one or few persons
sporadically; but most preferably, by billions!
7. The last point is; NAMASMARAN would certainly
enlighten, empower and enable some people; out of
those billions practicing NAMASMARAN; to evolve,
guide and consolidate the global conscience and thereby
manifest global unity and harmony and justice, through
globally benevolent proper policies!
References:
Namasmaran: Dr. Shriniwas Kashalikar
Sahasranetra: Dr. Shriniwas Kashalikar
Holistic Medicine: Dr. Shriniwas Kashalikar
Stress: Understanding and Management: Dr. Shriniwas
Kashalikar
Conceptual Stress: Dr. Shriniwas Kashalikar
All available for free download on
www.superliving.net
And
www.scribd.com
www.slideshare.net
www.docstoc.com
DR. SHRINIWAS KASHALIKAR