The document discusses how big data and analytics can optimize clinical trial efficiency. It notes that unstructured data makes up 80% of useful information and is growing faster than structured data. Traditional clinical trial protocols rely on limited data sources like medical histories and questionnaires, whereas expanded protocols could incorporate a wider range of data sources like other medical records. Graphical displays of contextual analyses and intuitive interfaces can provide insights at a glance. Actionable analytics derived from big data could drive clinical trial efficiency by defining measures, answering questions, and leading directly to meaningful actions.