The skin is the largest organ of the body, weighing approximately 4 kg. It has two layers - the epidermis and dermis. The skin protects the body, regulates temperature, and has sensory functions. The fascia is a fibrous tissue that surrounds muscles and organs. It has three types - superficial, deep, and subserous fascia. The deep fascia encloses muscles and sends intermuscular septa. It has several modifications like retinacula, aponeurosis, and sheaths. The fascia has functions like muscle gliding, organ suspension, and transmitting movement.
This document provides information on the anatomy and structure of the skin. It discusses the key layers and components of the skin, including the epidermis, dermis, hair follicles, sebaceous and sweat glands, nails, fascia, and skin receptors. It also briefly describes some common skin conditions like boils, carbuncles, cysts, and paronchia. Skin grafts are also mentioned. The skin provides protection, temperature regulation, sensation, and vitamin D synthesis for the body.
This document provides an overview of the key topics and assessments for a lesson on invertebrate animals. It will characterize the main groups of invertebrates, describe the general characteristics of large taxonomic groups and their importance, and value the importance of Andalusia's biodiversity. Assessments include exams, exercises, interactive games, investigations, and student presentations. The lesson will also cover the characteristics of major invertebrate groups including sponges, cnidarians, worms, molluscs, arthropods, and echinoderms.
The document discusses bones and cartilages. It describes the structure and types of cartilage, including elastic, fibrocartilage, and hyaline cartilage. It then covers the gross structure of bones, including compact and cancellous bone. Bone cells like osteoblasts, osteoclasts and osteocytes are also discussed. The functions of bone include mechanical support, mineral storage, and endocrine functions. Bone formation occurs through endochondral and intramembranous ossification. The document also outlines different types of bones such as long, short, flat, and irregular bones.
The skin has two main layers - the epidermis and dermis. The epidermis is composed of stratified squamous epithelium and provides a protective barrier. It contains no blood vessels. The dermis lies below the epidermis and is composed of connective tissue containing collagen, elastic fibers, and fibroblasts. It also contains structures like hair follicles, sweat and sebaceous glands, and nerves. The skin regulates body temperature, protects the body from microbes and injury, and contains sensory receptors for touch, temperature, and pain.
lecture 1 Clinical anatomy of the reproductive tract ,vulvovaginitis (1).pptxtengizbaindurishvili
The document provides details on the clinical anatomy and physiology of the female reproductive system. It describes the external genital organs including the labia majora, labia minora, clitoris, vestibule, urethral opening, and vaginal opening. It then discusses the internal reproductive organs like the uterus, fallopian tubes, ovaries, and their structures and functions. The blood supply, lymphatic drainage and innervation of the external and internal organs are also summarized.
lecture 1 Clinical anatomy of the reproductive tract ,vulvovaginitis.pptxgiadunkin
The document provides details on the clinical anatomy and physiology of the female reproductive system. It describes the external genital organs including the labia majora, labia minora, clitoris, vestibule, urethral opening, and vaginal opening. It then discusses the internal reproductive organs like the uterus, fallopian tubes, ovaries, and their structures. It provides information on blood supply, lymphatic drainage and innervation of the reproductive organs. The document is an in-depth reference of the anatomical structures and their clinical significance in the female reproductive system.
The eyelids develop from the frontonasal and maxillary processes during embryogenesis. They contain skin, muscle, fibrous tissue and glands that work together to protect the eye. The orbicularis oculi muscle helps with blinking while the levator palpebrae superioris muscle elevates the upper eyelid. The tarsal plates provide structure and the meibomian glands secrete oils to form the tear film. Blood vessels from the internal and external carotid arteries provide a rich blood supply to support the eyelids' functions.
The document provides an anatomy overview of the eyelids. It discusses the key structures of the eyelids including the orbicularis oculi muscle, levator palpebrae superioris muscle, tarsal plates, septum orbitale, canthi, caruncle, plica semilunaris, and eyelid margins. The document also describes the layers of the eyelid from skin to conjunctiva and the position and function of the eyelids.
This document provides information on the anatomy and structure of the skin. It discusses the key layers and components of the skin, including the epidermis, dermis, hair follicles, sebaceous and sweat glands, nails, fascia, and skin receptors. It also briefly describes some common skin conditions like boils, carbuncles, cysts, and paronchia. Skin grafts are also mentioned. The skin provides protection, temperature regulation, sensation, and vitamin D synthesis for the body.
This document provides an overview of the key topics and assessments for a lesson on invertebrate animals. It will characterize the main groups of invertebrates, describe the general characteristics of large taxonomic groups and their importance, and value the importance of Andalusia's biodiversity. Assessments include exams, exercises, interactive games, investigations, and student presentations. The lesson will also cover the characteristics of major invertebrate groups including sponges, cnidarians, worms, molluscs, arthropods, and echinoderms.
The document discusses bones and cartilages. It describes the structure and types of cartilage, including elastic, fibrocartilage, and hyaline cartilage. It then covers the gross structure of bones, including compact and cancellous bone. Bone cells like osteoblasts, osteoclasts and osteocytes are also discussed. The functions of bone include mechanical support, mineral storage, and endocrine functions. Bone formation occurs through endochondral and intramembranous ossification. The document also outlines different types of bones such as long, short, flat, and irregular bones.
The skin has two main layers - the epidermis and dermis. The epidermis is composed of stratified squamous epithelium and provides a protective barrier. It contains no blood vessels. The dermis lies below the epidermis and is composed of connective tissue containing collagen, elastic fibers, and fibroblasts. It also contains structures like hair follicles, sweat and sebaceous glands, and nerves. The skin regulates body temperature, protects the body from microbes and injury, and contains sensory receptors for touch, temperature, and pain.
lecture 1 Clinical anatomy of the reproductive tract ,vulvovaginitis (1).pptxtengizbaindurishvili
The document provides details on the clinical anatomy and physiology of the female reproductive system. It describes the external genital organs including the labia majora, labia minora, clitoris, vestibule, urethral opening, and vaginal opening. It then discusses the internal reproductive organs like the uterus, fallopian tubes, ovaries, and their structures and functions. The blood supply, lymphatic drainage and innervation of the external and internal organs are also summarized.
lecture 1 Clinical anatomy of the reproductive tract ,vulvovaginitis.pptxgiadunkin
The document provides details on the clinical anatomy and physiology of the female reproductive system. It describes the external genital organs including the labia majora, labia minora, clitoris, vestibule, urethral opening, and vaginal opening. It then discusses the internal reproductive organs like the uterus, fallopian tubes, ovaries, and their structures. It provides information on blood supply, lymphatic drainage and innervation of the reproductive organs. The document is an in-depth reference of the anatomical structures and their clinical significance in the female reproductive system.
The eyelids develop from the frontonasal and maxillary processes during embryogenesis. They contain skin, muscle, fibrous tissue and glands that work together to protect the eye. The orbicularis oculi muscle helps with blinking while the levator palpebrae superioris muscle elevates the upper eyelid. The tarsal plates provide structure and the meibomian glands secrete oils to form the tear film. Blood vessels from the internal and external carotid arteries provide a rich blood supply to support the eyelids' functions.
The document provides an anatomy overview of the eyelids. It discusses the key structures of the eyelids including the orbicularis oculi muscle, levator palpebrae superioris muscle, tarsal plates, septum orbitale, canthi, caruncle, plica semilunaris, and eyelid margins. The document also describes the layers of the eyelid from skin to conjunctiva and the position and function of the eyelids.
The document discusses the anatomy of skin and its appendages. It describes skin as the outer covering of the body made of two layers - epidermis and dermis. The epidermis is stratified squamous epithelium and the dermis is made of connective tissue. Skin contains pigments like melanin, carotene and haemoglobin. It has structures like hair follicles, sweat and sebaceous glands. Skin has functions like protection, regulation of temperature and synthesis of vitamin D. Some clinical conditions associated with skin like bed sores, fungal infections and vitiligo are also mentioned.
The document summarizes the anatomy of the female reproductive system. It describes the external genital organs which include the mons pubis, labia majora, labia minora, Bartholin's glands, clitoris and vestibule. It notes the three main functions of the external organs which are enabling sperm entry, protecting internal organs, and providing sexual pleasure. It then provides details on the structure and function of each external organ.
The skin consists of two main layers - the epidermis and dermis. The epidermis is made up of stratified squamous epithelium with the basal layer containing keratinocytes that proliferate and push upwards. As they migrate upwards through the strata, the keratinocytes flatten and fill with keratin to form the protective outer layer. The dermis lies below the epidermis and contains blood vessels, nerves, hair follicles and glands. The skin has important protective, sensory and temperature regulating functions.
Primary congenital glaucoma is a rare genetic congenital ocular disorder that affects children at birth. It is characterized by abnormally high intraocular pressures. This activity describes the etiology, risk factors, varied presentations, investigations, management guidelines, differential diagnosis, and prognosis for primary congenital glaucoma.
The document provides an overview of the musculoskeletal system including its components like bones, muscles, joints, ligaments and tendons. It discusses the functions of the musculoskeletal and skeletal systems. It describes the different types of muscles, bones, and joints. The document outlines how to examine the musculoskeletal system through general observation, palpation, and assessment of individual joints like the spine, shoulder, elbow, wrist, hip, knee, ankle and foot. It also lists and describes various pathologic conditions that can affect the musculoskeletal system including congenital diseases, acquired skeletal diseases, and other soft tissue disorders.
The document provides information on the integumentary system, skeletal system, and joints. It includes sections on the structure and functions of skin, as well as the structure of the skull, vertebral column, thoracic cage, and types of bones. Key points covered are the layers of the skin (epidermis and dermis), structures in the skin (sweat glands, hair follicles, sebaceous glands), functions of skin (protection, temperature regulation, sensation), and divisions of the skeletal system into the axial skeleton and appendicular skeleton.
This document discusses the various tissues and structures of the body. It describes the skin, superficial fascia, deep fascia, mucous membranes, serous membranes, ligaments, tendons, synovial sheaths, and tension lines. The skin is the outermost covering and largest organ, consisting of two layers - the epidermis and dermis. The superficial fascia lies beneath the skin and stores fat. Deep fascia invests muscles and forms intermuscular septa. Mucous and serous membranes line internal cavities. Ligaments attach bone to bone, tendons attach muscle to bone, and synovial sheaths envelop tendons at friction points. Tension lines influence skin creases
This document provides information on the muscles of the head and neck. It begins with an introduction to muscle tissue and classification of muscles. It then describes the specific muscle groups of the head and neck region, including facial muscles, masticatory muscles, and neck muscles. For each group, the individual muscles are defined with their origins, insertions, nerve supply, blood supply, and actions. Applied clinical anatomy is also discussed. In summary, this document categorizes and defines the important muscles of the head and neck region through detailed descriptions of muscle groups, locations and functions.
The dermis is made of connective tissue containing collagen and elastic fibers that provide strength and elasticity. It contains fibroblasts, mast cells, macrophages, blood vessels and nerve endings. The deepest dermis layer is the subcutaneous tissue containing fat. Within the dermis are sweat and sebaceous glands, hair follicles with arrector pili muscles, and sensory receptors for touch and pain. The dermis gives the skin strength and elasticity but loss of collagen and elastic fibers with age leads to wrinkles and stretch marks.
The document summarizes the anatomy of the female pelvis. It describes that the pelvis is formed by the two hip bones, sacrum, and coccyx. Each hip bone consists of three parts: ilium, ischium, and pubis. It provides details on the structures and landmarks of the pelvis. It also describes the pelvic joints, ligaments, shapes, diameters of the pelvic inlet, cavity, and outlet that are important for childbirth.
The integumentary system consists of the skin, hair, and nails and acts as a protective barrier for the body. It has several important functions, including protecting against pathogens and injury, regulating body temperature, removing waste, and producing vitamin D. The skin is the body's largest organ and is composed of two main layers - the epidermis and dermis. The epidermis is a thin outer layer made up of dead skin cells that sheds regularly, while the dermis contains blood vessels, glands, and hair follicles. Together, these layers provide protection, temperature regulation, sensation, and other critical functions for the body.
The document discusses the structure, composition, and functions of the integumentary system. It describes the three main layers of skin - the epidermis, dermis, and hypodermis. It details the differences between these layers and lists the skin's main functions like protection, temperature regulation, and sensory functions. The document also examines glands associated with the skin like sweat glands and sebaceous glands. It discusses skin derivatives like hair, nails, scales and compares skin structures across different chordates.
The document discusses the structure, composition, and functions of the integumentary system. It describes the three main layers of skin - the epidermis, dermis, and hypodermis. It details the differences between these layers and lists the various functions of skin, including protection, temperature regulation, vitamin synthesis, and sensory functions. The document also discusses glands associated with the skin like sweat glands and sebaceous glands, as well as skin derivatives like hair, nails, scales, and feathers.
The document discusses sex cell differentiation and gamete formation in humans and other animals. It covers the processes of oogenesis and spermatogenesis, including the migration of primordial germ cells and proliferation of eggs and sperm. It also describes fertilization, including the structures and stages of egg and sperm cells, their fusion during conception, and the early cleavage and differentiation stages of embryonic development.
Tissue is a group of cells that work together to perform a specific function. There are two main types of tissue: plant and animal. Plant tissue remains stationary and is supplied by the plant, while animal tissue can move according to the animal's needs. Tissue is further classified as meristematic or permanent. Meristematic tissue is actively dividing and responsible for plant growth. Permanent tissue has stopped dividing and taken on specific roles. Examples of permanent tissues include parenchyma, collenchyma, sclerenchyma, xylem, and phloem. In animals, main tissues include epithelial, muscular, connective, adipose, and blood tissues.
This document discusses the anatomy, physiology, life cycles, and taxonomy of sea cucumbers and shore crabs. It notes that sea cucumbers are soft-bodied, radially symmetrical echinoderms that use tube feet for locomotion and have tentacles and a mouth for feeding. They reproduce sexually through external fertilization and have a planktonic larval stage before settling on the sea floor as adults. Shore crabs are arthropods with external features like antennae, legs, a carapace, pincers and eyes, and they feed on other invertebrates as part of their life cycle.
Robert Hooke observed a thin slice of cork under a microscope in 1665 and saw it had a honeycomb-like structure made of tiny compartments, which he named "cells". This was the first time it was discovered that living organisms are made of small structures. Over subsequent decades, other scientists like Van Leeuwenhoek, Brown, and Purkinje further studied cells and proposed the Cell Theory - that all living things are composed of cells, cells are the basic unit of life, and new cells are produced from existing cells. The development of the microscope was crucial to these discoveries of cells and cellular structures.
Annelids are segmented worms that include earthworms, leeches, and bristle worms. They are divided into three classes based on characteristics like the presence of bristles. Polychaetes are bristle worms that live mainly in marine environments. Oligochaetes include earthworms and live in soil and freshwater. Leeches can be found in freshwater or terrestrial environments. Annelids have bilateral symmetry and segmented bodies, and most reproduce sexually. They play important ecological roles in areas like soil enrichment.
These lecture slides, by Dr Sidra Arshad, offer a simplified look into the mechanisms involved in the regulation of respiration:
Learning objectives:
1. Describe the organisation of respiratory center
2. Describe the nervous control of inspiration and respiratory rhythm
3. Describe the functions of the dorsal and respiratory groups of neurons
4. Describe the influences of the Pneumotaxic and Apneustic centers
5. Explain the role of Hering-Breur inflation reflex in regulation of inspiration
6. Explain the role of central chemoreceptors in regulation of respiration
7. Explain the role of peripheral chemoreceptors in regulation of respiration
8. Explain the regulation of respiration during exercise
9. Integrate the respiratory regulatory mechanisms
10. Describe the Cheyne-Stokes breathing
Study Resources:
1. Chapter 42, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 36, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 13, Human Physiology by Lauralee Sherwood, 9th edition
Osteoporosis - Definition , Evaluation and Management .pdfJim Jacob Roy
Osteoporosis is an increasing cause of morbidity among the elderly.
In this document , a brief outline of osteoporosis is given , including the risk factors of osteoporosis fractures , the indications for testing bone mineral density and the management of osteoporosis
The document discusses the anatomy of skin and its appendages. It describes skin as the outer covering of the body made of two layers - epidermis and dermis. The epidermis is stratified squamous epithelium and the dermis is made of connective tissue. Skin contains pigments like melanin, carotene and haemoglobin. It has structures like hair follicles, sweat and sebaceous glands. Skin has functions like protection, regulation of temperature and synthesis of vitamin D. Some clinical conditions associated with skin like bed sores, fungal infections and vitiligo are also mentioned.
The document summarizes the anatomy of the female reproductive system. It describes the external genital organs which include the mons pubis, labia majora, labia minora, Bartholin's glands, clitoris and vestibule. It notes the three main functions of the external organs which are enabling sperm entry, protecting internal organs, and providing sexual pleasure. It then provides details on the structure and function of each external organ.
The skin consists of two main layers - the epidermis and dermis. The epidermis is made up of stratified squamous epithelium with the basal layer containing keratinocytes that proliferate and push upwards. As they migrate upwards through the strata, the keratinocytes flatten and fill with keratin to form the protective outer layer. The dermis lies below the epidermis and contains blood vessels, nerves, hair follicles and glands. The skin has important protective, sensory and temperature regulating functions.
Primary congenital glaucoma is a rare genetic congenital ocular disorder that affects children at birth. It is characterized by abnormally high intraocular pressures. This activity describes the etiology, risk factors, varied presentations, investigations, management guidelines, differential diagnosis, and prognosis for primary congenital glaucoma.
The document provides an overview of the musculoskeletal system including its components like bones, muscles, joints, ligaments and tendons. It discusses the functions of the musculoskeletal and skeletal systems. It describes the different types of muscles, bones, and joints. The document outlines how to examine the musculoskeletal system through general observation, palpation, and assessment of individual joints like the spine, shoulder, elbow, wrist, hip, knee, ankle and foot. It also lists and describes various pathologic conditions that can affect the musculoskeletal system including congenital diseases, acquired skeletal diseases, and other soft tissue disorders.
The document provides information on the integumentary system, skeletal system, and joints. It includes sections on the structure and functions of skin, as well as the structure of the skull, vertebral column, thoracic cage, and types of bones. Key points covered are the layers of the skin (epidermis and dermis), structures in the skin (sweat glands, hair follicles, sebaceous glands), functions of skin (protection, temperature regulation, sensation), and divisions of the skeletal system into the axial skeleton and appendicular skeleton.
This document discusses the various tissues and structures of the body. It describes the skin, superficial fascia, deep fascia, mucous membranes, serous membranes, ligaments, tendons, synovial sheaths, and tension lines. The skin is the outermost covering and largest organ, consisting of two layers - the epidermis and dermis. The superficial fascia lies beneath the skin and stores fat. Deep fascia invests muscles and forms intermuscular septa. Mucous and serous membranes line internal cavities. Ligaments attach bone to bone, tendons attach muscle to bone, and synovial sheaths envelop tendons at friction points. Tension lines influence skin creases
This document provides information on the muscles of the head and neck. It begins with an introduction to muscle tissue and classification of muscles. It then describes the specific muscle groups of the head and neck region, including facial muscles, masticatory muscles, and neck muscles. For each group, the individual muscles are defined with their origins, insertions, nerve supply, blood supply, and actions. Applied clinical anatomy is also discussed. In summary, this document categorizes and defines the important muscles of the head and neck region through detailed descriptions of muscle groups, locations and functions.
The dermis is made of connective tissue containing collagen and elastic fibers that provide strength and elasticity. It contains fibroblasts, mast cells, macrophages, blood vessels and nerve endings. The deepest dermis layer is the subcutaneous tissue containing fat. Within the dermis are sweat and sebaceous glands, hair follicles with arrector pili muscles, and sensory receptors for touch and pain. The dermis gives the skin strength and elasticity but loss of collagen and elastic fibers with age leads to wrinkles and stretch marks.
The document summarizes the anatomy of the female pelvis. It describes that the pelvis is formed by the two hip bones, sacrum, and coccyx. Each hip bone consists of three parts: ilium, ischium, and pubis. It provides details on the structures and landmarks of the pelvis. It also describes the pelvic joints, ligaments, shapes, diameters of the pelvic inlet, cavity, and outlet that are important for childbirth.
The integumentary system consists of the skin, hair, and nails and acts as a protective barrier for the body. It has several important functions, including protecting against pathogens and injury, regulating body temperature, removing waste, and producing vitamin D. The skin is the body's largest organ and is composed of two main layers - the epidermis and dermis. The epidermis is a thin outer layer made up of dead skin cells that sheds regularly, while the dermis contains blood vessels, glands, and hair follicles. Together, these layers provide protection, temperature regulation, sensation, and other critical functions for the body.
The document discusses the structure, composition, and functions of the integumentary system. It describes the three main layers of skin - the epidermis, dermis, and hypodermis. It details the differences between these layers and lists the skin's main functions like protection, temperature regulation, and sensory functions. The document also examines glands associated with the skin like sweat glands and sebaceous glands. It discusses skin derivatives like hair, nails, scales and compares skin structures across different chordates.
The document discusses the structure, composition, and functions of the integumentary system. It describes the three main layers of skin - the epidermis, dermis, and hypodermis. It details the differences between these layers and lists the various functions of skin, including protection, temperature regulation, vitamin synthesis, and sensory functions. The document also discusses glands associated with the skin like sweat glands and sebaceous glands, as well as skin derivatives like hair, nails, scales, and feathers.
The document discusses sex cell differentiation and gamete formation in humans and other animals. It covers the processes of oogenesis and spermatogenesis, including the migration of primordial germ cells and proliferation of eggs and sperm. It also describes fertilization, including the structures and stages of egg and sperm cells, their fusion during conception, and the early cleavage and differentiation stages of embryonic development.
Tissue is a group of cells that work together to perform a specific function. There are two main types of tissue: plant and animal. Plant tissue remains stationary and is supplied by the plant, while animal tissue can move according to the animal's needs. Tissue is further classified as meristematic or permanent. Meristematic tissue is actively dividing and responsible for plant growth. Permanent tissue has stopped dividing and taken on specific roles. Examples of permanent tissues include parenchyma, collenchyma, sclerenchyma, xylem, and phloem. In animals, main tissues include epithelial, muscular, connective, adipose, and blood tissues.
This document discusses the anatomy, physiology, life cycles, and taxonomy of sea cucumbers and shore crabs. It notes that sea cucumbers are soft-bodied, radially symmetrical echinoderms that use tube feet for locomotion and have tentacles and a mouth for feeding. They reproduce sexually through external fertilization and have a planktonic larval stage before settling on the sea floor as adults. Shore crabs are arthropods with external features like antennae, legs, a carapace, pincers and eyes, and they feed on other invertebrates as part of their life cycle.
Robert Hooke observed a thin slice of cork under a microscope in 1665 and saw it had a honeycomb-like structure made of tiny compartments, which he named "cells". This was the first time it was discovered that living organisms are made of small structures. Over subsequent decades, other scientists like Van Leeuwenhoek, Brown, and Purkinje further studied cells and proposed the Cell Theory - that all living things are composed of cells, cells are the basic unit of life, and new cells are produced from existing cells. The development of the microscope was crucial to these discoveries of cells and cellular structures.
Annelids are segmented worms that include earthworms, leeches, and bristle worms. They are divided into three classes based on characteristics like the presence of bristles. Polychaetes are bristle worms that live mainly in marine environments. Oligochaetes include earthworms and live in soil and freshwater. Leeches can be found in freshwater or terrestrial environments. Annelids have bilateral symmetry and segmented bodies, and most reproduce sexually. They play important ecological roles in areas like soil enrichment.
These lecture slides, by Dr Sidra Arshad, offer a simplified look into the mechanisms involved in the regulation of respiration:
Learning objectives:
1. Describe the organisation of respiratory center
2. Describe the nervous control of inspiration and respiratory rhythm
3. Describe the functions of the dorsal and respiratory groups of neurons
4. Describe the influences of the Pneumotaxic and Apneustic centers
5. Explain the role of Hering-Breur inflation reflex in regulation of inspiration
6. Explain the role of central chemoreceptors in regulation of respiration
7. Explain the role of peripheral chemoreceptors in regulation of respiration
8. Explain the regulation of respiration during exercise
9. Integrate the respiratory regulatory mechanisms
10. Describe the Cheyne-Stokes breathing
Study Resources:
1. Chapter 42, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 36, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 13, Human Physiology by Lauralee Sherwood, 9th edition
Osteoporosis - Definition , Evaluation and Management .pdfJim Jacob Roy
Osteoporosis is an increasing cause of morbidity among the elderly.
In this document , a brief outline of osteoporosis is given , including the risk factors of osteoporosis fractures , the indications for testing bone mineral density and the management of osteoporosis
Travel vaccination in Manchester offers comprehensive immunization services for individuals planning international trips. Expert healthcare providers administer vaccines tailored to your destination, ensuring you stay protected against various diseases. Conveniently located clinics and flexible appointment options make it easy to get the necessary shots before your journey. Stay healthy and travel with confidence by getting vaccinated in Manchester. Visit us: www.nxhealthcare.co.uk
Histololgy of Female Reproductive System.pptxAyeshaZaid1
Dive into an in-depth exploration of the histological structure of female reproductive system with this comprehensive lecture. Presented by Dr. Ayesha Irfan, Assistant Professor of Anatomy, this presentation covers the Gross anatomy and functional histology of the female reproductive organs. Ideal for students, educators, and anyone interested in medical science, this lecture provides clear explanations, detailed diagrams, and valuable insights into female reproductive system. Enhance your knowledge and understanding of this essential aspect of human biology.
Cell Therapy Expansion and Challenges in Autoimmune DiseaseHealth Advances
There is increasing confidence that cell therapies will soon play a role in the treatment of autoimmune disorders, but the extent of this impact remains to be seen. Early readouts on autologous CAR-Ts in lupus are encouraging, but manufacturing and cost limitations are likely to restrict access to highly refractory patients. Allogeneic CAR-Ts have the potential to broaden access to earlier lines of treatment due to their inherent cost benefits, however they will need to demonstrate comparable or improved efficacy to established modalities.
In addition to infrastructure and capacity constraints, CAR-Ts face a very different risk-benefit dynamic in autoimmune compared to oncology, highlighting the need for tolerable therapies with low adverse event risk. CAR-NK and Treg-based therapies are also being developed in certain autoimmune disorders and may demonstrate favorable safety profiles. Several novel non-cell therapies such as bispecific antibodies, nanobodies, and RNAi drugs, may also offer future alternative competitive solutions with variable value propositions.
Widespread adoption of cell therapies will not only require strong efficacy and safety data, but also adapted pricing and access strategies. At oncology-based price points, CAR-Ts are unlikely to achieve broad market access in autoimmune disorders, with eligible patient populations that are potentially orders of magnitude greater than the number of currently addressable cancer patients. Developers have made strides towards reducing cell therapy COGS while improving manufacturing efficiency, but payors will inevitably restrict access until more sustainable pricing is achieved.
Despite these headwinds, industry leaders and investors remain confident that cell therapies are poised to address significant unmet need in patients suffering from autoimmune disorders. However, the extent of this impact on the treatment landscape remains to be seen, as the industry rapidly approaches an inflection point.
- Video recording of this lecture in English language: https://youtu.be/kqbnxVAZs-0
- Video recording of this lecture in Arabic language: https://youtu.be/SINlygW1Mpc
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Rasamanikya is a excellent preparation in the field of Rasashastra, it is used in various Kushtha Roga, Shwasa, Vicharchika, Bhagandara, Vatarakta, and Phiranga Roga. In this article Preparation& Comparative analytical profile for both Formulationon i.e Rasamanikya prepared by Kushmanda swarasa & Churnodhaka Shodita Haratala. The study aims to provide insights into the comparative efficacy and analytical aspects of these formulations for enhanced therapeutic outcomes.
These lecture slides, by Dr Sidra Arshad, offer a quick overview of the physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar lead (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
6. Describe the flow of current around the heart during the cardiac cycle
7. Discuss the placement and polarity of the leads of electrocardiograph
8. Describe the normal electrocardiograms recorded from the limb leads and explain the physiological basis of the different records that are obtained
9. Define mean electrical vector (axis) of the heart and give the normal range
10. Define the mean QRS vector
11. Describe the axes of leads (hexagonal reference system)
12. Comprehend the vectorial analysis of the normal ECG
13. Determine the mean electrical axis of the ventricular QRS and appreciate the mean axis deviation
14. Explain the concepts of current of injury, J point, and their significance
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. Chapter 3, Cardiology Explained, https://www.ncbi.nlm.nih.gov/books/NBK2214/
7. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Our backs are like superheroes, holding us up and helping us move around. But sometimes, even superheroes can get hurt. That’s where slip discs come in.
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8 Surprising Reasons To Meditate 40 Minutes A Day That Can Change Your Life.pptxHolistified Wellness
We’re talking about Vedic Meditation, a form of meditation that has been around for at least 5,000 years. Back then, the people who lived in the Indus Valley, now known as India and Pakistan, practised meditation as a fundamental part of daily life. This knowledge that has given us yoga and Ayurveda, was known as Veda, hence the name Vedic. And though there are some written records, the practice has been passed down verbally from generation to generation.
2. SKIN
• SKIN IS THE LARGEST SENSORY ORGAN OF THE BODY. ITS WEIGHT IS 16% OF BODY WEIGHT
AND IS ABOUT 4 KG IN WEIGHT. THE SKIN FORMS AN OUTER PROTECTIVE COVER FOR THE
ENTIRE SURFACE OF THE BODY. THE THICKNESS OF SKIN VARIES IN DIFFERENT PARTS OF THE
BODY. ACCORDINGLY, THERE ARE TWO TYPES OF SKIN.
1. THICK SKIN: IT COVERS THE BACK OF THE BODY, PALMS AND SOLES. IT IS HAIRLESS.
2. THIN SKIN: AT OTHER PLACES OF BODY, THE SKIN IS THIN AND HAIRY. VERY THIN SKIN IS
PRESENT ON EYELIDS.
• MUCOCUTANEOUS JUNCTION
IT IS THE PLACE WHERE THE SKIN IS CONTINUOUS WITH THE MUCOUS MEMBRANE.
• EXAMPLE: LIPS, ANUS, AND EYELIDS.
3. • THE SKIN IS THE OUTER COVERING OF THE BODY. IT PROVIDES THE DYNAMIC
INTERPHASE BETWEEN THE BODY AND THE EXTERNAL ENVIRONMENT.
• THE SKIN IS CONSIDERED AS AN ORGAN SINCE IT CONSISTS OF SEVERAL KINDS
OF TISSUES THAT ARE STRUCTURALLY ARRANGED TO FUNCTION TOGETHER.
• IT IS THE LARGEST ORGAN OF THE BODY, COVERING OVER 7600 SQ. CM (3000
SQ. IN) AREA IN AN AVERAGE ADULT AND ACCOUNTS FOR APPROXIMATELY 7%
OF THE PERSON'S TOTAL BODY WEIGHT.
• THE GENERAL APPEARANCE AND CONDITION OF THE SKIN IS CLINICALLY
IMPORTANT BECAUSE IT PROVIDES CLUES TO CERTAIN BODY FUNCTIONS AND
DYSFUNCTIONS. THUS, SKIN REFLECTS OUR GENERAL HEALTH. A HEALTHY SKIN
INDICATES A HEALTHY BODY.
4. STRUCTURE OF SKIN
• THE SKIN CONSISTS OF TWO PRINCIPAL LAYERS: THE EPIDERMIS AND THE
DERMIS.
• THE SURFACE EPITHELIUM OF SKIN IS EPIDERMIS. IT IS OF THE STRATIFIED
SQUAMOUS VARIETY. THE VARIOUS APPENDAGES OF SKIN, VIZ. SWEAT GLANDS,
SEBACEOUS GLANDS, HAIR AND NAILS ARE SPECIALIZED DERIVATIVES OF THIS
EPIDERMIS. THE DEEPER DERMIS CONSISTS MAINLY OF BUNDLES OF COLLA- GEN
FIBRES TOGETHER WITH SOME ELASTIC TISSUE, BLOOD VESSELS, LYMPHATICS
AND NERVE FIBRES.
5. FUNCTIONS
• PROTECTION: PROTECTS THE BODY FROM CHEMICALS, ULTRAVIOLET RAYS, INJURY AND
MICROORGANISMS. MECHANICAL
• BARRIER: ACTS AS A BARRIER AND PREVENTS WATER ABSORPTION.
• TEMPERATURE REGULATION: IT HELPS IN MAINTAINING NORMAL BODY TEMPERATURE.
IN SUMMER BY SECRETION AND EVAPORATION OF SWEAT. IN WINTER DUE TO THE
PRESENCE OF SUBCUTANEOUS FAT, IT MAINTAINS BODY TEMPERATURE.
• SENSORY: PRESENCE OF VARIOUS SENSORY NERVE ENDINGS IN THE SKIN FACILITATES
PERCEPTION OF PAIN, TEMPERATURE, TOUCH, ETC. SENSATIONS.
• EXCRETORY: EXCRETION OF UREA.
• VITAMIN D: IT SYNTHESIZES VITAMIN D
6. FASCIA
THE WORD FASCIA IS DERIVED FROM LATIN = "BAND FASCIA IS SINGULAR AND FASCIAE ARE PLEURAL.
• DEFINITION
FIBROUS TISSUE NETWORK IN THE FORM A SHEET OR FLAT BAND.
• LOCATION
• BELOW THE SURFACE OF THE SKIN, COVERING AND SEPARATING MUSCLES, ORGANS AND OTHER
TISSUES.
• STRUCTURE
• DENSE REGULAR CONNECTIVE TISSUE. CONTAINS CLOSELY PACKED BUNDLES OF COLLAGEN FIBERS.
IT IS ORIENTED IN A WAVY PATTERN PARALLEL TO THE DIRECTION OF PULL.
7. • FUNCTIONS
• SLIDING AND GLIDING SURFACE FOR MUSCLES TO REDUCE FRICTION.
• SUSPENDS ORGANS IN THEIR ANATOMICAL LOCATION.
• TRANSMITS MOVEMENT FROM MUSCLES TO THE BONES TO WHICH THEY ARE
ATTACHED.
• SUPPORTIVE AND MOVABLE WRAPPING FOR NERVES AND BLOOD VESSELS AS THEY PASS
THROUGH AND BETWEEN THE MUSCLES.
8. TYPE
• THREE DIFFERENT TYPES DEPENDING ANATOMICAL LOCATION
AND FUNCTION.
• SUPERFICIAL FASCIA
• DEEP FASCIA
• SUBSEROUS FASCIA
9. SUPERFICIAL FASCIA
• IT IS A SUBCUTANEOUS LAYER OF LOOSE AREOLAR TISSUE WHICH UNITES DERMIS OF SKIN TO
THE UNDERLYING DEEP FASCIA. IT ALLOWS MOBILITY OF THE DERMIS ON THE UNDERLYING
STRUCTURES. IT IS HEAVILY INFILTRATED WITH FAT. THE AMOUNT OF FAT VARIES IN DIFFERENT
PARTS OF THE BODY. THE SUPERFICIAL FASCIA ALMOST EVERYWHERE IN THE BODY CONTAINS
FAT EXCEPT IN THE
1. EYELIDS
2. EXTERNAL EAR/PINNA
3. PENIS
4. SCROTUM
5. FLEXION CREASES OF THE DIGITS
10. • THE AMOUNT OF FAT IN SUPERFICIAL FASCIA IS MORE IN FEMALES AND CHILDREN. THE FAT BEING A BAD
CONDUCTOR OF HEAT, THE FEMALES AND CHILDREN FEEL LESS COLD. FURTHER, IT IS THE MAIN FACTOR
RESPONSIBLE FOR THE SMOOTH EXTERNAL CONTOURS OF THE FEMALES. SPECIAL FAT DEPOSITS AT
CERTAIN SITES IN WOMEN FORM THEIR SECONDARY SEXUAL CHARACTERISTICS.
• THESE SITES ARE
1. GLUTEAL AND LUMBAR REGION
2. FRONT OF THIGH
3. ANTERIOR ABDOMINAL WALL BELOW THE NAVEL (UMBILICUS)
4. BREASTS
11. 5. POST-DELTOID REGION
6. CERVICAL THORACIC REGION
• THE SUPERFICIAL FASCIA ACTS AS A DISTRIBUTING LAYER, IN WHICH THE BLOOD
VESSELS, LYMPHATICS AND NERVES CAN TRAVEL BEFORE ENTERING THE DERMIS.
12. THE SUBCUTANEOUS FASCIA IN THE LOWER ANIMAL CONTAINS A THIN SHEET OF MUSCLE CALLED
PANNICULUS CARNOSUS. ITS FIBRES ARE INSERTED INTO THE SKIN. THE TWITCH OF ITS FIBRES PROMPTS THE
INSECTS TO GO AWAY OR FLY OFF.
• IN HUMANS, THE PANNICULUS CARNOSUS IS REPRESENTED BY:
-MUSCLES OF FACIAL EXPRESSION (SKELETAL MUSCLES)
- PLATYSMA IN THE NECK (SKELETAL MUSCLE)
- SUBAREOLAR MUSCLE OF THE BREAST (SMOOTH MUSCLE)
- PALMARIS BREVIS (SKELETAL MUSCLE)
-DARTOS IN THE SCROTAL WALL (SMOOTH MUSCLE)
-CORRUGATOR CUTIS ANI (SMOOTH MUSCLE).
13. FUNCTIONS OF SUPERFICIAL FASCIA
• THE FUNCTIONS OF SUPERFICIAL FASCIA ARE AS FOLLOWS:
• 1. FORMS AN INSULATING LAYER DEEP TO SKIN
• 2. RESPONSIBLE FOR SMOOTH EXTERNAL CONTOURS OF FEMALES AND CHILDREN
• 3. ALLOWS MOBILITY OF THE SKIN ON THE UNDERLYING STRUCTURES
• 4. PROVIDES EASY PASSAGE TO NERVE, VESSELS AND LYMPHATICS
• 5. ACTS AS CUSHION AT CERTAIN SITES (DUE TO EXCESSIVE ACCUMULATION OF FAT,
E.G. BUTTOCKS)
14. CLINICAL CORRELATION
• SUBCUTANEOUS INJECTIONS:
• SUBCUTANEOUS INJECTIONS ARE PAINFUL DUE TO PRESENCE OF PAIN
RECEPTORS IN IT. DRUGS ADMINISTERED BY THIS ROUTE ARE ABSORBED
SLOWLY BECAUSE SUBCUTANEOUS TISSUE HAS POOR BLOOD SUPPLY. ONLY
SMALL DOSES (0.5-1 ML) OF WATER-SOLUBLE DRUGS ARE GIVEN
SUBCUTANEOUSLY. FOR EXAMPLE, INSULIN INJECTIONS IN DIABETIC PERSONS
ARE GIVEN SUBCUTANEOUSLY IN SMALL DOSES FOR SLOW RELEASE OVER A
LONG DURATION.
15. SITES OF SUBCUTANEOUS INJECTIONS:
• THE IDEAL SITES OF SUBCUTANEOUS INJECTIONS ARE
(A) POSTERIOR ASPECT OF ARM
(B) ANTERIOR ASPECT OF FOREARM
(C) ANTERIOR ABDOMINAL WALL
(D) ANTERIOR ASPECT OF THIGH.
16. DEEP FASCIA
• THE DEEP FASCIA IS A TOUGH, INELASTIC MEMBRANE OF FIBROUS
TISSUE WHICH ENCLOSES THE BODY DEEP TO SUBCU- TANEOUS
TISSUE, LIKE A TIGHT SLEEVE. IT KEEPS THE SOFT TISSUES IN PLACE
AND MAINTAINS THE SHAPE OF THE BODY. THE DEEP FASCIA IS BEST
MARKED IN THE LIMBS AND NECK. IN THE LIMBS, IT SENDS SEPTA
(INTERMUSCULAR SEPTA) BETWEEN THE GROUPS OF MUSCLES TO
ATTACH WITH THE PERIOSTEUM OF THE BONE. THESE SEPTAE ENABLE
A GROUP OF MUSCLES TO CONTRACT INDIVIDUALLY AND SLIDE FREELY
OVER THE ADJACENT MUSCLE GROUPS.
17. • IN THE NECK, IT FORMS THREE LAYERS:
1. GENERAL INVESTING LAYER, WHICH ENCLOSES THE STRUCTURES OF THE NECK LIKE
A COLLAR
2. PRETRACHEAL FASCIA, WHICH PASSES IN FRONT OF THE TRACHEA
3. PREVERTEBRAL FASCIA, IN FRONT OF THE CERVICAL OF PART THE VERTEBRAL
COLUMN.
THUS, THE NECK IS DIVIDED INTO TWO COMPARTMENTS: VISCERAL COMPARTMENT
AND MUSCULOSKELETAL COMPARTMENT.
18. MODIFICATIONS OF DEEP FASCIA
• RETINACULA. AT CERTAIN SITES, DEEP FASCIA
THICKENS TO FORM THICK BANDS TO RETAIN THE
TENDON OF LONG MUS- CLES IN PLACE AND
PREVENT THEIR BOWSTRINGING DURING ACTION
OF THESE MUSCLES. THESE BANDS ARE CALLED
RET- INACULA, VIZ. FLEXOR AND EXTENSOR
RETINACULA AROUND WRIST AND ANKLE JOINTS.
19. APONEUROSIS. IN PALMS AND SOLES, IT
THICKENS TO FORM PALMAR AND PLANTAR
APONEUROSIS TO PROTECT THE UNDERLYING
STRUCTURES. IN TRUE SENSE, AN
APONEUROSIS IS A THICK, WIDE SHEET OF
FIBROUS TISSUE THAT PROVIDES ATTACHMENT
TO MUSCLES. THE PALMAR AND PLANTAR
APONEUROSIS REPRESENT THE DEGENERATED
TENDONS OF PALMARIS LONGUS AND
PLANTARIS MUSCLES, RESPECTIVELY.
20. FIBROUS SHEATHS. AT CERTAIN SITES, DEEP FASCIA CONDENSES TO FORM A SHEATH AROUND
NEUROVASCULAR BUNDLES, VIZ.
(A) CAROTID SHEATH ENCLOSING COMMON CAROTID ARTERY, INTERNAL JUGULAR VEIN AND
VAGUS NERVE
(B) AXILLARY SHEATH ENCLOSING AXILLARY ARTERY AND AXILLARY VEIN (DEEP FASCIA IS DENSE
AROUND THE ARTERY AND RATHER LOOSE AROUND THE VEINS TO ALLOW THE VEINS TO DISTEND)
21. 4. FIBROUS CAPSULES. AT SOME SITES, IT SPLITS
TO ENCLOSE CERTAIN GLANDS TO FORM THEIR
CAPSULE, VIZ. PAROTID GLAND, SUBMANDIBULAR
GLAND, THYROID GLAND ETC.
5. INTEROSSEOUS MEMBRANES. IN THE
FOREARM AND LEG, THE DEEP FASCIA IS
MODIFIED TO FORM INTEROSSEOUS
MEMBRANES.
6. INTERMUSCULAR SEPTA. IN THE LIMBS, DEEP
FASCIA SENDS FIBROUS SEPTA FROM ITS DEEP
SURFACE TO HELP FORM THE COMPARTMENTS
OF THE MUSCLES.
22.
23. 7. FIBROUS FLEXOR SHEATHS. ON THE FLEXOR
SURFACES OF FINGERS AND TOES, THE DEEP
FASCIA THICKENS TO FORM THE FIBROUS FLEXOR
SHEATH AROUND THE LONG FLEXOR TENDONS.
THESE SHEATHS PREVENT THE TENDONS FROM
BOWING OUT OF POSITION.
8. LIGAMENTS. THE LIGAMENTS OF JOINTS ARE
CONSIDERED AS LOCALIZED THICKENED BANDS
OF THE DEEP FASCIA.
9. FASCIAL SHEATH. IT FORMS SHEATH AROUND
CERTAIN MUSCLES, VIZ. PSOAS SHEATH.
24. CLINICAL CORRELATION
• SINCE DEEP FASCIA DEFINES FASCIAL PLANES BETWEEN THE MUS-CLES,
THESE PLANES FORM POTENTIAL PATHWAYS FOR INFECTION TO SPREAD.
• PUS TENDS TO FORCE ITS WAY ALONG THE LINES OF LEAST RESISTANCE
PROVIDED BY THE PLANES OF THE DEEP FASCIA.
• PUS CAN TRACK DOWN THROUGH THE FASCIAL SLEEVES FORMED BY
DEEP FASCIA AROUND THE BLOOD VESSELS AND MUSCLES, E.G. PUS
FROM ROOT OF NECK CAN TRACK DOWN INTO THE ARM THROUGH
AXILLARY SHEATH.
25. • PUS FROM TUBERCULAR THORACIC SPINE CAN TRACK DOWN IN THE INGUINAL
REGION THROUGH PSOAS SHEATH.
• SURGEONS CAN OPERATE ALONG THE FASCIAL PLANES WITH MINIMAL INJURY TO
THE ADJOINING STRUCTURES. DEEP FASCIA IS LEAST MARKED, I.E. SCARCELY
DEMONSTRABLE IN THE REGION OF ANTERIOR ABDOMINAL WALL AND IS
CONSIDERED TO BE ABSENT.
26. SITES WHERE DEEP FASCIA IS ABSENT
• THE DEEP FASCIA IS ABSENT AT THE FOLLOWING SITES:
1. FACE
2. BREAST
3. ANTERIOR ABDOMINAL WALL
4. PENIS AND SCROTUM
5. ISCHIORECTAL FOSSA
27. • THE DEEP FASCIA IS VERY SENSITIVE.
ITS NERVE SUPPLY IS DERIVED FROM
1. NERVES SUPPLYING OVERLAPPING SKIN.
2. NERVES SUPPLYING ENCLOSED MUSCLES.
28. FUNCTIONS OF DEEP FASCIA
1. KEEPS THE UNDERLYING STRUCTURES IN POSITION AND PRESERVES THE
CHARACTERISTIC SURFACE CONTOUR, VIZ. LIMBS, NECK
2. PROVIDES EXTRA SURFACE FOR MUSCULAR ATTACHMENTS
3. FACILITATES VENOUS AND LYMPHATIC DRAINAGE
4. BINDS BONES, VIZ. INTEROSSEOUS MEMBRANES
5. RETAINS THE LONG TENDONS IN PLACE TO PREVENT THEIR BOWSTRINGING AND
ALSO SERVES AS PULLEYS DURING THEIR ACTIONS