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Skin
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At the end of this class you should be
able to …
• Describe gross & microscopic structure of skin
• Enumerate functions of skin
• Appreciate importance of anatomy of skin in
clinical practice
Integumentary system
Integumentary - covering; covers outside of the body
Consists of:
 Skin & appendages
 Hair
 Nails
 Glands
Introduction
• Largest organ
• Continues m/m at orifices
• 7 % of body weight
• Surface area: 1.5 to 2 Sq.
meters
• Thickness: 0.5 to 3mm
• Consists of:
– Epidermis
– Dermis
Layers
• Dermis
–Deep layer, connected to hypodermis
–2 layers
• Superficial papillary layer
• Deep reticular layer
Dermis: papillary layer
• Loose CT with collagen &
elastic fibers
• Peg-like projections -dermal
papillae - fit into reciprocal
depressions on undersurface of
epidermis
• Dermal papillae contain
capillary loops & free nerve
endings
Dermis: Reticular Layer
• Main layer
• Elastin & collagen
produce:
– Structural strength
– Cleavage lines
– Stretch marks- striae
• Epidermis
–Avascular
–5 Layers
–Str sq ker ep
Epidermis: cells
• Keratinocytes: Produce keratin for strength
• Melanocytes: Contribute to skin color
• Langerhans’ cells: Part of immune system
• Merkel’s cells: Detect light touch &
pressure
C
L
G
S
B
Appendages
• Hair
– Except palms, soles, lips, nipples, parts of external
genitalia & distal segments of fingers & toes
• Glands
– Sebaceous
– Sudoriferous (sweat)
– Ceruminous
– Mammary
• Nail
Hair
Hair
Sweat glands
• Sweat - blood filtrate
– 99% water with some salts
– Contains traces of metabolic wastes
• Types:
– Eccrine gland
• Most numerous – produce true sweat
– Apocrine gland
• Confined to axillary, anal & genital areas
• Produce special kind of sweat
Sebaceous glands
• Over entire body except palms & soles
• Simple alveolar glands
• Secrete sebum- oily substance
• Holocrine secretion – entire cell breaks up to
form secretion
• Functions - Softens & lubricates hair & skin
Nail
• Scale-like modification of epidermis on the distal, dorsal
surface of fingers & toes
• Parts: Free edge, Body, Root, Nail folds, Eponychium,
Lunula
• Elastin & collagen
fibers oriented in
directions
• Important in surgery
• When incision parallel
to lines
• Less gaping
• Faster healing
• Less scar tissue
Cleavage lines (Lines of Langer)
Dermatome
Skin color
Determined by 3 factors
1. Pigments
• Melanin
• Carotene
• Albinism: Deficiency or absence of pigment
2. Blood circulating through skin
• Imparts reddish hue- Hb & Oxy Hb
• Cyanosis: Blue color caused by decrease in blood oxygen
3. Thickness of stratum corneum
Functions of skin
 Protection
 Sensation
 Metabolism
 Temperature regulation
 Vitamin D production
 Excretion
 Regulation of pH
 Absorption
 Secretion
 Storage
Applied anatomy
• Skin color in clinical conditions
– Pale - Anemia
– Yellow - jaundice
– Blue – cyanosis
• Skin grafts
– Split thickness grafts - Epidermis & tips of
dermal papillae is used
– Full thickness graft - Both epidermis & dermis is
used
Rule of nines
• Estimates severity of burns
• Burns are critical if:
– Over 25% second degree burns
– Over 10% third degree burns
– Third degree burns on face, hands, or feet
Du BOIS FORMULA
To calculate surface area of a person
A = W x H x 71.84
 A: Surface area in square cm
 W: Weight in kilogram
 H: Height in cm
Skin

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Skin

  • 2. At the end of this class you should be able to … • Describe gross & microscopic structure of skin • Enumerate functions of skin • Appreciate importance of anatomy of skin in clinical practice
  • 3. Integumentary system Integumentary - covering; covers outside of the body Consists of:  Skin & appendages  Hair  Nails  Glands
  • 4. Introduction • Largest organ • Continues m/m at orifices • 7 % of body weight • Surface area: 1.5 to 2 Sq. meters • Thickness: 0.5 to 3mm • Consists of: – Epidermis – Dermis
  • 5. Layers • Dermis –Deep layer, connected to hypodermis –2 layers • Superficial papillary layer • Deep reticular layer
  • 6. Dermis: papillary layer • Loose CT with collagen & elastic fibers • Peg-like projections -dermal papillae - fit into reciprocal depressions on undersurface of epidermis • Dermal papillae contain capillary loops & free nerve endings
  • 7. Dermis: Reticular Layer • Main layer • Elastin & collagen produce: – Structural strength – Cleavage lines – Stretch marks- striae
  • 9.
  • 10.
  • 11. Epidermis: cells • Keratinocytes: Produce keratin for strength • Melanocytes: Contribute to skin color • Langerhans’ cells: Part of immune system • Merkel’s cells: Detect light touch & pressure
  • 13.
  • 14.
  • 15.
  • 16. Appendages • Hair – Except palms, soles, lips, nipples, parts of external genitalia & distal segments of fingers & toes • Glands – Sebaceous – Sudoriferous (sweat) – Ceruminous – Mammary • Nail
  • 17. Hair
  • 18. Hair
  • 19.
  • 20. Sweat glands • Sweat - blood filtrate – 99% water with some salts – Contains traces of metabolic wastes • Types: – Eccrine gland • Most numerous – produce true sweat – Apocrine gland • Confined to axillary, anal & genital areas • Produce special kind of sweat
  • 21.
  • 22. Sebaceous glands • Over entire body except palms & soles • Simple alveolar glands • Secrete sebum- oily substance • Holocrine secretion – entire cell breaks up to form secretion • Functions - Softens & lubricates hair & skin
  • 23.
  • 24. Nail • Scale-like modification of epidermis on the distal, dorsal surface of fingers & toes • Parts: Free edge, Body, Root, Nail folds, Eponychium, Lunula
  • 25. • Elastin & collagen fibers oriented in directions • Important in surgery • When incision parallel to lines • Less gaping • Faster healing • Less scar tissue Cleavage lines (Lines of Langer)
  • 26.
  • 27.
  • 29. Skin color Determined by 3 factors 1. Pigments • Melanin • Carotene • Albinism: Deficiency or absence of pigment 2. Blood circulating through skin • Imparts reddish hue- Hb & Oxy Hb • Cyanosis: Blue color caused by decrease in blood oxygen 3. Thickness of stratum corneum
  • 30. Functions of skin  Protection  Sensation  Metabolism  Temperature regulation  Vitamin D production  Excretion  Regulation of pH  Absorption  Secretion  Storage
  • 31. Applied anatomy • Skin color in clinical conditions – Pale - Anemia – Yellow - jaundice – Blue – cyanosis • Skin grafts – Split thickness grafts - Epidermis & tips of dermal papillae is used – Full thickness graft - Both epidermis & dermis is used
  • 32. Rule of nines • Estimates severity of burns • Burns are critical if: – Over 25% second degree burns – Over 10% third degree burns – Third degree burns on face, hands, or feet
  • 33. Du BOIS FORMULA To calculate surface area of a person A = W x H x 71.84  A: Surface area in square cm  W: Weight in kilogram  H: Height in cm