Skin is the outer covering of the body. In humans, it is the largest organ of the integumentary system. The skin has multiple layer of ectodermal tissue & guards the underlying muscles, bones, ligaments & internal organs. Human skin is similar to the other mammals but the only difference is that it is not protected by fur. Human skin is covered by hair follicles.

2.  Medicity Hospital is a top tier multispecialty hospital &
Super specialty hospital in Navi Mumbai (Kharghar).
 It has wide range of medical & super specialties including
intervention & dignoistics and is well equipped with latest &
modern state of art equipments for immediate & advanced
medical care & best Gynaecologists and joint replacement in
Navi Mumbai.
 Located at Kharghar, sector7, Aum Sai CHS, Plot no-C/23,
next to Royal Tulip Hotel
Medicity Hospital

3.  Skin is the outer covering of the body. In humans, it is the
largest organ of the integumentary system. The skin has
multiple layer of ectodermal tissue & guards the underlying
muscles, bones, ligaments & internal organs.
 Human skin is similar to the other mammals but the only
difference is that it is not protected by fur. Human skin is
covered by hair follicles.
 There are two types of skin Hairy & Glabrous ( free from
hair & smooth).
 Skin plays key immunity role in protecting the body against
the pathogens excessive water loss.
Skin

4.  Functions of skin:- Insulation, Temperature regulation,
Sensation, Synthesis of Vitamin D & protecting of Vitamin
B folates.
 Severely damaged will try to heal by forming scar tissue,
which is often discolored & depigmented.
 A medical expert who deals with skin problems is known as
Skin Specialist or Dermatologist.

5.  It is the infection of skin. Infection of the skin is
distinguished from Dermatitis, which is inflammation of the
skin, but skin infection can result in skin inflammation and it
is known as Infective Dermatitis.
 The diagnosis and management of patients with
inflammatory skin disease remains a very challenging and
rewarding aspect of ‘core’ dermatology practice.
 Skills in the management of chronic disease need to be
developed, such as the ability to communicate
risk/benefit of different therapy strategies and reach joint
decisions with patients.
Skin Infection

6.  Bacterial Skin Infection:-
a) Impetigo is a highly contagious bacterial skin infection &
commonly found is school going children. It is primarily
caused by Staphylococcus Aureus.
b) Erysipelas is an acute streptococcus bacterial infection of
deep epidermis with lymphatic spread.
c) Cellulitis is a diffuse inflammation of connective tissue
with severe inflammation of dermal layers of the skin.
 Fungal:- Fungal skin infections may present as either a
superficial or deep infection of skin, hair & nails.
Cause

7.  Parasitic Infestation & Bites:- Parasitic infestation, stings
& bites in human are caused by several group of organisms
belonging to the following: Annelida, Arthropoda, Bryozoa,
Chordata & Cindaria etc.
 Viral:- It is related to the virus.

8.  Drugs: Some drugs can precipitate or worsen psoriasis .
 Sunlight: Most patients’ psoriasis improves in the sun, but some
(about 10%) get worse.
 Metabolic: Pregnancy generally improves psoriasis, but it can worsen
post-partum. Generalized pustular psoriasis can be triggered post-
partum, or by hypocalcaemia.
 Stress: There is strong evidence that stress can exacerbate psoriasis.
Patients with high levels of worry respond less well to therapy.
 Alcohol: Heavy consumption can worsen existing disease.
 Smoking: There is a strong link between smoking and palmoplantar
pustular psoriasis, particularly in females.
Environmental Cause

9.  The diagnosis of psoriasis is usually straightforward, but
confusion can arise in flexural psoriasis, scalp psoriasis and
palmoplantar psoriasis.
 Flexural psoriasis:- There are some patients who present
with indistinct inflammatory lesions in the flexural areas
who have inflamed skin at some typical psoriatic sites
(always check for psoriasis at the umbilicus in this case), but
who also have involvement at sites typical of seborrhoeic
dermatitis.
Diagnosis

10.  This so-called ‘sebo-psoriasis’ may need to be treated with a
combination of topical antifungals, topical steroids and then
standard psoriasis therapies. Do not be worried if this
presentation leaves you feeling not sure of the diagnosis —
it can be very difficult.
 Scalp psoriasis:- It is usually easy to diagnose; there are
typical lesions elsewhere and the lesions are very clearly
defined. Plaques on the scalp can develop severe adherent
scaling, termed pityriasis amiantacea. Hair growth is usually
normal unless severely affected.
 Palmoplantar pustular psoriasis:- Psoriasis of the palms
or soles can sometimes be difficult to differentiate from
chronic eczema. Look carefully for vesicles — these clear
sago-like small blebs are diagnostic of eczema.

11.  Pustular psoriasis:- Sheets of small, sterile pustules can
appear in plaques of otherwise normal-appearing skin. When
generalized, the patient can be systemically unwell, and this
represents a dermatological emergency.
 Nail psoriasis:- Nail changes are seen in 25–50% of
psoriasis sufferers (Figure 4.4). These include pitting,
ridging and discoloration of the nail, subungual
hyperkeratosis, onycholysis and a circular ‘oil spot’
appearance.

12. http://www.khargharmedicityhospital.com