Sjogren's syndrome is an autoimmune disorder characterized by dry eyes and dry mouth due to reduced functioning of the salivary and lacrimal glands. It can occur as a primary condition or secondary to other autoimmune diseases like rheumatoid arthritis. The disease is more common in women over age 40 and is associated with genetic and immunological factors. Symptoms include dryness, eye and mouth pain, and enlarged salivary glands. Histological examination shows lymphocytic infiltration of the glands. Treatment focuses on symptom relief; prognosis depends on the extent of systemic involvement.