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•FORFORTHYEARBPHARM
•PRESENTEDBY
SHAFNA.K.K
FORTHBPHARM
 The cause of hypertension for 95% of the people is unknown
 The cause of the 5% of people with hypertension is mainly due to
the poor diet and lifestyle choices (Eg.Smoking ,excessive alcohol
intake )
 Food that contain high sodium and low potassium have been
proven to increase blood pressure levels .
 Lack of exercise ,smoking, high alcohol intake, poor diet are all
factors that increase hypertension.
 Higher blood pressure can lead to increased
chances of:
1. Diabetes
2. Heart complications or stroke
3. Aneurysms
4. Weakened or narrow blood vessels
5. Complications with memory and understanding
 Age
 Race
 Family History
 Obesity
 Nutrition
 Alcohol
 Stress
 Chronic conditions
A study investigated the effects of dietary changes for three years on
hypertension
 There were four treatment groups in the study (reduced
calories ,reduced sodium and increased potassium)
 Evidence showed that all four groups had an effect in
lowering blood pressure but the reduced caloric diet had the
highest reduction
 Conclusion : reduced sodium and caloric diet have implications
on preventing hypertension
SYSTOLIC
DIASTOLIC
BLOOD PRESSURE 120mmHG BLOOD
PRESSURE
*When heart contracting 80mmHG *When
heart relaxing
 BLOOD PRESSUREINCREASES
ACE Inhibitors: Calcium channel blockers:
Captopril Amlodepin
Lisinopril Nefidepin
Enalapril Verapamil
Fosinopril Diltiesm
Angiotensin Antagonist :
Losartan
Valsartan
Adrenergic neuron blocker:
Reserpine
Quanethidine monosulphate
B-Adrenergic Blockers:
Proponolol
Methoprolol
Vasodialator:
Hydrolazine
venoxidin
Angiotensin 1
COOH
Captopril
sh
Decrease the binding of zn
DENATURATION OF ACE
CATIONICSITE
Zn2+
ANGIOTENSIN 2
 INCREASE THE
BLOOD PRESSURE
 ADRENERGIC
BLOCKERS CAN BE
GIVEN TO REDUCE
THE BLOOD PRESSURE
 Calcium
Channel
Blockers
Reduce
Blood pressure
 Control diet
 Manage stress
 Limit alcohol
 Stop smoking
 exercise
LIFE STYLE CHANGES AND MEDICATION
MAY
REDUCE HIGH BLOOD PRESSURE TO HEALTHY
LEVELS

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hypertension

  • 2.  The cause of hypertension for 95% of the people is unknown  The cause of the 5% of people with hypertension is mainly due to the poor diet and lifestyle choices (Eg.Smoking ,excessive alcohol intake )  Food that contain high sodium and low potassium have been proven to increase blood pressure levels .  Lack of exercise ,smoking, high alcohol intake, poor diet are all factors that increase hypertension.
  • 3.  Higher blood pressure can lead to increased chances of: 1. Diabetes 2. Heart complications or stroke 3. Aneurysms 4. Weakened or narrow blood vessels 5. Complications with memory and understanding
  • 4.  Age  Race  Family History  Obesity  Nutrition  Alcohol  Stress  Chronic conditions
  • 5. A study investigated the effects of dietary changes for three years on hypertension  There were four treatment groups in the study (reduced calories ,reduced sodium and increased potassium)  Evidence showed that all four groups had an effect in lowering blood pressure but the reduced caloric diet had the highest reduction  Conclusion : reduced sodium and caloric diet have implications on preventing hypertension
  • 6. SYSTOLIC DIASTOLIC BLOOD PRESSURE 120mmHG BLOOD PRESSURE *When heart contracting 80mmHG *When heart relaxing
  • 7.
  • 8.
  • 9.
  • 10.
  • 12.
  • 13. ACE Inhibitors: Calcium channel blockers: Captopril Amlodepin Lisinopril Nefidepin Enalapril Verapamil Fosinopril Diltiesm Angiotensin Antagonist : Losartan Valsartan Adrenergic neuron blocker: Reserpine Quanethidine monosulphate B-Adrenergic Blockers: Proponolol Methoprolol Vasodialator: Hydrolazine venoxidin
  • 14.
  • 15. Angiotensin 1 COOH Captopril sh Decrease the binding of zn DENATURATION OF ACE CATIONICSITE Zn2+ ANGIOTENSIN 2
  • 16.  INCREASE THE BLOOD PRESSURE  ADRENERGIC BLOCKERS CAN BE GIVEN TO REDUCE THE BLOOD PRESSURE
  • 17.
  • 19.  Control diet  Manage stress  Limit alcohol  Stop smoking  exercise
  • 20. LIFE STYLE CHANGES AND MEDICATION MAY REDUCE HIGH BLOOD PRESSURE TO HEALTHY LEVELS