The reality of moving towards precision medicineElia Stupka
How do we move towards precision medicine? How can we deliver on the big data in health promise? Who will be the enablers and players? Pharma, Big Tech, or newcomers?
Paul Aylin, Co-Director of the Dr Foster Unit at Imperial College London, gives concrete examples of using a specific statistical model for monitoring care quality, cumulative sum (CUSUM).
2015 09-14 Precision Medicine 2015, London, Alain van GoolAlain van Gool
Outline of my view hoe personalized health(care) is more than just targeted medicines, also including personal motivation and actions towards disease prevention. It also outlines 4 key factors that should be in order for optimal personalized health(care): 1. start with patients first, 2. Accelerate translation research to application, 3. Copy best practice, 4. Spread the word.
Using real-world evidence to investigate clinical research questionsKarin Verspoor
Adoption of electronic health records to document extensive clinical information brings with it the opportunity to utilise that information to support clinical research, and ultimately to support clinical decision making. In this talk, I discuss both these opportunities and the challenges that we face when working with real-world clinical data, and introduce some of the strategies that we are adopting to make this data more usable, and to extract more value from it. I specifically discuss the use of natural language processing to transform clinical documentation into structured data for this purpose.
Dr Martin Bardsley: Use of Retrospective Matching Methods 30 June 2014Nuffield Trust
Martin Bardsley, Director of Research, Nuffield Trust explores the use of retrospective matching methods to study health services and other sectors.
Dr Martin Bardsley spoke at the Nuffield Trust event: The future of the hospital, in June 2014.
Understand what healthcare analytics is.
Identify the 5-stage Analytics Program Lifecycle (APL).
Understand how data analytics can be used in healthcare.
Check it on Experfy: https://www.experfy.com/training/courses/introduction-to-healthcare-analytics.
UCSF Informatics Day 2014 - Keith R. Yamamoto, "Precision Medicine"CTSI at UCSF
Keith R. Yamamoto, PhD — Opening Remarks – Precision Medicine
Vice Chancellor for Research
Executive Vice Dean of the School of Medicine
Professor of Cellular and Molecular Pharmacology
UCSF
Martin Utley, Director of the Clinical Operational Research Unit at University College London, reflects upon his involvement in the launch of specific tools to monitor care quality for paediatric cardiac surgery.
Precision Medicine is now a funded NIH initiative and an organic movement in the clinic and at the research institute. Based on work with Genomics England, multiple large pharmaceutical firms, and research hospitals, attendees will learn about the best practices for epidemiology, signal detection, research, and the clinical diagnostics associated with Precision Medicine, including the development of high-scale bio-repositories that link traditional patient data with genomic information. Come hear about how leadership, collaboration, consent, and compute can lead to success or failure in your Precision Medicine initiative, and how to bring your stakeholders together for an aligned mission response.
Overview of the Patient-Centered Outcomes Research Institute (PCORI), how PCORI views Patient-Centered Outcomes Research and how this is related to PCORI’s major funding mechanisms.
Factors Associated with Antenatal Care Service Utilization among Women with C...YogeshIJTSRD
Maternal and neonatal mortality remains a public health burden around the globe most especially in developing countries. A well utilized antenatal care ANC is however among the identified interventions to reduce this burden of maternal and neonatal mortality rates. A lot of factors therefore predispose, enable and cause mothers to identify the need to utilize this service ANC .This study employed descriptive cross sectional survey design. A semi structured questionnaire consisting of demographic profile of the respondents, their knowledge about ANC services and the level of ANC utilization. Logistic regression analysis techniques and chi square were used for the categorical variables to examine the associations between the dependent and independent variables. Data analysis was done using the Statistical Package for Social Science software SPSS version 22. Majority 87 of postpartum mothers in the Sunyani municipality attended ANC at least once during their last pregnancy of which 95.6 had four or more visits and 77.1 initiated their ANC attendance within their first trimester. It was further observed that 97.3 of the mothers had good knowledge about ANC. Marital status and ANC knowledge were found to be significantly associated with ANC attendance. Stephen Owusu Sekyere | Kodua Freda "Factors Associated with Antenatal Care Service Utilization among Women with Children under Five Years in Sunyani Municipality, Ghana" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-5 | Issue-3 , April 2021, URL: https://www.ijtsrd.com/papers/ijtsrd39882.pdf Paper URL: https://www.ijtsrd.com/other-scientific-research-area/other/39882/factors-associated-with-antenatal-care-service-utilization-among-women-with-children-under-five-years-in-sunyani-municipality-ghana/stephen-owusu-sekyere
The reality of moving towards precision medicineElia Stupka
How do we move towards precision medicine? How can we deliver on the big data in health promise? Who will be the enablers and players? Pharma, Big Tech, or newcomers?
Paul Aylin, Co-Director of the Dr Foster Unit at Imperial College London, gives concrete examples of using a specific statistical model for monitoring care quality, cumulative sum (CUSUM).
2015 09-14 Precision Medicine 2015, London, Alain van GoolAlain van Gool
Outline of my view hoe personalized health(care) is more than just targeted medicines, also including personal motivation and actions towards disease prevention. It also outlines 4 key factors that should be in order for optimal personalized health(care): 1. start with patients first, 2. Accelerate translation research to application, 3. Copy best practice, 4. Spread the word.
Using real-world evidence to investigate clinical research questionsKarin Verspoor
Adoption of electronic health records to document extensive clinical information brings with it the opportunity to utilise that information to support clinical research, and ultimately to support clinical decision making. In this talk, I discuss both these opportunities and the challenges that we face when working with real-world clinical data, and introduce some of the strategies that we are adopting to make this data more usable, and to extract more value from it. I specifically discuss the use of natural language processing to transform clinical documentation into structured data for this purpose.
Dr Martin Bardsley: Use of Retrospective Matching Methods 30 June 2014Nuffield Trust
Martin Bardsley, Director of Research, Nuffield Trust explores the use of retrospective matching methods to study health services and other sectors.
Dr Martin Bardsley spoke at the Nuffield Trust event: The future of the hospital, in June 2014.
Understand what healthcare analytics is.
Identify the 5-stage Analytics Program Lifecycle (APL).
Understand how data analytics can be used in healthcare.
Check it on Experfy: https://www.experfy.com/training/courses/introduction-to-healthcare-analytics.
UCSF Informatics Day 2014 - Keith R. Yamamoto, "Precision Medicine"CTSI at UCSF
Keith R. Yamamoto, PhD — Opening Remarks – Precision Medicine
Vice Chancellor for Research
Executive Vice Dean of the School of Medicine
Professor of Cellular and Molecular Pharmacology
UCSF
Martin Utley, Director of the Clinical Operational Research Unit at University College London, reflects upon his involvement in the launch of specific tools to monitor care quality for paediatric cardiac surgery.
Precision Medicine is now a funded NIH initiative and an organic movement in the clinic and at the research institute. Based on work with Genomics England, multiple large pharmaceutical firms, and research hospitals, attendees will learn about the best practices for epidemiology, signal detection, research, and the clinical diagnostics associated with Precision Medicine, including the development of high-scale bio-repositories that link traditional patient data with genomic information. Come hear about how leadership, collaboration, consent, and compute can lead to success or failure in your Precision Medicine initiative, and how to bring your stakeholders together for an aligned mission response.
Overview of the Patient-Centered Outcomes Research Institute (PCORI), how PCORI views Patient-Centered Outcomes Research and how this is related to PCORI’s major funding mechanisms.
Factors Associated with Antenatal Care Service Utilization among Women with C...YogeshIJTSRD
Maternal and neonatal mortality remains a public health burden around the globe most especially in developing countries. A well utilized antenatal care ANC is however among the identified interventions to reduce this burden of maternal and neonatal mortality rates. A lot of factors therefore predispose, enable and cause mothers to identify the need to utilize this service ANC .This study employed descriptive cross sectional survey design. A semi structured questionnaire consisting of demographic profile of the respondents, their knowledge about ANC services and the level of ANC utilization. Logistic regression analysis techniques and chi square were used for the categorical variables to examine the associations between the dependent and independent variables. Data analysis was done using the Statistical Package for Social Science software SPSS version 22. Majority 87 of postpartum mothers in the Sunyani municipality attended ANC at least once during their last pregnancy of which 95.6 had four or more visits and 77.1 initiated their ANC attendance within their first trimester. It was further observed that 97.3 of the mothers had good knowledge about ANC. Marital status and ANC knowledge were found to be significantly associated with ANC attendance. Stephen Owusu Sekyere | Kodua Freda "Factors Associated with Antenatal Care Service Utilization among Women with Children under Five Years in Sunyani Municipality, Ghana" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-5 | Issue-3 , April 2021, URL: https://www.ijtsrd.com/papers/ijtsrd39882.pdf Paper URL: https://www.ijtsrd.com/other-scientific-research-area/other/39882/factors-associated-with-antenatal-care-service-utilization-among-women-with-children-under-five-years-in-sunyani-municipality-ghana/stephen-owusu-sekyere
This year's 3rd Annual TCGC: The Clinical Genome Conference, held June 10-12, 2014 in San Francisco, is a three-day event that weaves together the science of sequencing and the business of implementing genomics in the clinic. It uniquely illustrates the mutual influence of those areas and the need to therefore consider the needs, challenges and opportunities of both - from next-generation sequencing and variant interpretation to insurance reimbursement and electronic health records - throughout the entire research process.Learn more at http://www.clinicalgenomeconference.com
Decision makers in the healthcare field like doctors, patients and policy makers need access to clinical evidence to address issues that have bearing on the health of the population and the treatment prescribed and thereby on the financials implications of the healthcare industry.
- Discover new methods for managing clinical next-gen data with insights from Pfizer, Boston Children’s Hospital and AstraZeneca
- Uncover and critique the latest technologies out there for you to use in clinical trials. Mayo Clinic, Merck and Harvard Medical School let you into their trade secrets
- Hear the genomics strategies that Roche, Millennium and Regeneron are using for discovery and validation of clinically actionable biomarkers
-Bristol-Myers Squibb, Takeda and Partners Healthcare the role that NGS can play when implementing an effective strategy in the lab to speed up CDx development
- Learn how to integrate molecular details into medical decision making, with fresh data from Washington University School of Medicine and Genzyme
Jobs and Career Opportunity in Clinical Research, CDM and Pharmacovigilance. How to enter in Clinical Research Industry. For more details you can also visit our portal, we will be happy to assist you.
1. July 6, 2016 Page 1
Shaun Cooley,BS, MPH
104 Hazzard St, Asheville, NC, 28801 | (813) 486-7729 | stcooley@health.usf.edu or
Shaun.Cooley@va.gov
THERAPEUTIC RESEARCH EXPERIENCE
Phasell-lV: 2 years
PTSD:Effectsof New Psychotherapy Combatting Military Sexual Trauma/PTSD - 2 years
Maternal Immunology:Effectsof Natural Stressors on the Maternal Immunology - 2 years
Clinical Immunology:ToxoplasmaGondii - 2 years
Neurology: MultipleSclerosis PharmacologicalClinical Trial – 8 months
Oncology:Lung Cancer Surgical & Pharmacological Clinical Trials- 8 months
PUBLICATIONS
· Kip KE, Rosenzweig L, Hernandez DF, Shuman A, Diamond DM, Girling SA, Sullivan KL, Wittenberg
T, Witt AM, Lengacher CA, Anderson B, McMillan SC. Accelerated Resolution Therapy for
treatment of pain secondary to symptoms of combat-related posttraumatic stress disorder
EuropeanJournalofPsychotraumatology.5:24066, 2014.
· Groer M, Duffy A, Morse S, Kane B, Zaritt J, Roberts S, Ashmeade T. Cytokines, Chemokines, and
GrowthFactors in Banked Human Donor Milk for Preterm Infants. Journalof human lactation:
official journalof InternationalLactationConsultantAssociation.,2014
· Thibeau, Shelley; Ochsner Health System, Center for Nursing Research D'Apolito,Karen;
Vanderbilt University,School of Nursing Cooley,Shaun; University of South Florida, College of
Nursing, Biohavioral Lab; Vanderbilt University,School of Nursing, Maternal Stress Milk
with Immune Components in African American Mothers of Healthy Term Infants BreastFeeding
Medicine(BFM-2015-0117)
NOTABLE PROJECTS
· Camargo J, Cooley,S , Emechebe, N, Reedy, P,Alman,A ,TheAssociationofWalking for Exerciseand
BodyMassIndex:ACross-SectionalStudyofthe HispanicEstablishedPopulationsofthe
EpidemiologicalStudyoftheElderly,Department of Epidemiology and Biostatistics, College of
Public Health, University of South Florida
· Cooley, S, Flu Proof,Primary PreventionProgram forDecreasing the Number Influenza Cases on
the University of South Florida, Tampa Campus. Using the Precede-ProceedHealth Behavior
Model we created an economically feasible campus wide health promotion program forthe
university. This program was adopted by student health services and is projected to decrease the
number of seasonal influenza cases by 30 percent.
2. July 6, 2016 Page 2
EDUCATION
PHD CANDIDATE |COLLEGE OFNURSING |UNIVERSITYOF SOUTH FLORIDA,TAMPA,FL|
ANTICIPATED GRAUDATIONDATE 10MAY2018
· Major: Research in Nursing
· Minor: Statistics
· Related coursework: Research Design, Analysis and Measurement, InnovativeSymptom
Management, Research Design Theory
MASTERS INPUBLIC HEALTH|COLLEGE OFEPIDEMIOLOGY&BIOSTATISTICS | UNIVERSITY
OF SOUTHFLORIDA,TAMPA,FL| GRADUATED 10MAY2015
· Major: Epidemiology
· Minor: Biostatistics
· Related coursework: Biostatistics, Categorical Data Analysis, Conducting Clinical Trials, Health
Behavior Models, Health Policy,EpidemiologicalMethods Development, Infectious Epidemiology,
Epidemiology of Mental Disorders, Statistical Analysis Software 9.3 & 9.4 and SPSS 21 & 22
BACHELOROFSCIENCE |UNIVERSITYOFWEST FLORIDA, PENSACOLA,FL|GRADUATED
05MAY2010
· Major: Pre-Medical
· Minor: Laboratory Sciences
· Related coursework: Biochemistry, Genetics, Cellular Biology, Zoology,Metabolism,
Pathophysiology,Ecology,Comparative Anatomy, Physiology,Microbiology,Developmental
Biology,Inorganic Chemistry, Organic Chemistry
CERTIFICATIONS
· Applied Biostatistics | University of South Florida | 05May2014
· Advanced Epidemiology | University of South Florida | 06May2014
· Bio-Hazardous Waste Removal| University of South Florida| 11Nov2013
· Certified Pharmacy Technician | State of Florida Department of Health | 18Dec2012
PROFESSIONAL EXPERIENCE
RESEARCHCOORDINATOR |CHARLESGEORGEVAMEDICALCENTER |07DEC 2015–
PRESENT
· Ensuring proper quality and validity of study data, and compliancewith all federal regulations
and sponsor standard operating procedures.
· Responsible forparticipating in individual and team projects to facilitatequality improvements of
the regional clinical trial management process.
· Workwith existing hospital systems of care to ensure patient safety maintained at all times
· Using electronic health records to screen patients forenrollment
3. July 6, 2016 Page 3
JUNIOR BIOSTATISTICIAN|UNIVERSITYOFSOUTH FLORIDA | 01AUG2015-01DEC 2015)
· Data manager formulti-million dollar research projects
· Public health consultant for database design and data collectiontools
· Survey database designer fornumerous published authors
INDEPENDENT LABORATORYCONTRACTOR| VANDERBILTUNIVERSITY|27AUG2014 –
27AUG 2015
· Analyzed several hundred patient milk samples using ELISA plates for maternal immunological
components
· Ensured proper laboratory technique and maintenance of laboratory equipment as well as bio-
hazardous waste removal
· Responsible foranalysis of research specimens, data collectionfor analysis, compiling analysis
report.
· Created a preliminary report on immune stressors and their correlation with demographic
variables
DATABASEMANAGERAND DATAARCHITECT |UNIVERSITYOFSOUTH FLORIDA |01SEP2013
-05DEC2015
· Create databases forstudy tools (CES-D , PDSQ,PCL-M, PSQUI)
· Create SAS 9.3 , 9.4 (Statistical Analysis Software) programs tobe used foranalysis
· Create new patient data collectioninstruments for strength of association measures
· Grant proposal, fulfilled required IRB (Internal Review Board) procedures and policies
· FDA regulation compliance
BIOSTATISTICS TEACHINGASSISTANT|UNIVERSITYOFSOUTH FLORIDA |01SEP2013-
07DEC2015
· Advanced Nursing Pathophysiology and Advanced Multivariate Statistical Models
· Hold lectures and web conferences on weekly material modules
· Provideinput on research study design and methods
· Teach students proper data analysis techniques and their prospective steps in SPSS 21 , 22
CERTIFIED PHARMACYTECHNICIAN|PUBLIXPHARMACY,TAMPA|21JAN2012-17JUL2014
· Prescription entry, dispense controllednarcotics
· Finalize prior authorizations and product substitution at pharmacist discretion
· EnforceFDA regulations
· Maintain controlled substances inventory
· Ensure proper use of EFORCE (Electronic-FloridaOnline Reporting of Controlled Substances
Evaluation)to fulfilllong-term pain patient needs
4. July 6, 2016 Page 4
SOFTWARE EXPERTISE
MicrosoftOfficeSuite
Windows OPSand Macintosh OPS
Quintiles Survey Creation Program
SPSS Statistical Analysis Softwareversions 21 & 22
SAS Statistical Analysis Software versions 9.3 and 9.4
McKesson Enterprise Pharmacy Systems