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the presumptive identification of 
unrecognized disease or defect by the 
application of tests, examinations or other 
procedures which can be applied rapidly to 
sort out those who probably have the disease 
from those who probably do not
Criteria for screening
Characteristics of a diagnostic test
Accuracy of a screening 
 The test should give a true 
measurement of the attribute under 
investigation and provide consistent 
results in repeated trials more over it 
should have high sensitivity and 
specificity for the disease in question
Specificity—The ability of a test to give a positive 
finding when the person is tested truly has the 
disease under study 
Sensitivity—the ability of a test to give a negative 
finding when the person tested is free from the 
disease under study 
sensitivity and specificity both expressed in %
CALCULATING SPECIFICITY AND SENSITIVITY 
The fourfold contingency table is used
SPECIFICITY
SENSITIVITY
PREDICTIVE VALUES 
 Positive Predictive Value is the probability that patients with a 
positive screening test truly have the disease
 Negative Predictive Value is the probability that patients with a 
negative screening test truly do not have the disease
REFERENCES 
http://gim.unmc.edu/dxtests/howto.htm 
http://www.fpnotebook.com/Prevent/Epi/TstSnstvty.htm 
http://sphweb.bumc.bu.edu/otlt/MPH-Modules/ 
EP/EP713_Screening/EP713_Screening5.html#positiveandneg 
ativepredictivevalue 
Thorner and Remein. Principlesand Procedures in the Evaluation of 
Screening for Disease, US Department HEW, Public Health Monograph 
No. 67, 1961
Screening

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Screening

  • 1.
  • 2. the presumptive identification of unrecognized disease or defect by the application of tests, examinations or other procedures which can be applied rapidly to sort out those who probably have the disease from those who probably do not
  • 4.
  • 5. Characteristics of a diagnostic test
  • 6. Accuracy of a screening  The test should give a true measurement of the attribute under investigation and provide consistent results in repeated trials more over it should have high sensitivity and specificity for the disease in question
  • 7. Specificity—The ability of a test to give a positive finding when the person is tested truly has the disease under study Sensitivity—the ability of a test to give a negative finding when the person tested is free from the disease under study sensitivity and specificity both expressed in %
  • 8. CALCULATING SPECIFICITY AND SENSITIVITY The fourfold contingency table is used
  • 11. PREDICTIVE VALUES  Positive Predictive Value is the probability that patients with a positive screening test truly have the disease
  • 12.  Negative Predictive Value is the probability that patients with a negative screening test truly do not have the disease
  • 13. REFERENCES http://gim.unmc.edu/dxtests/howto.htm http://www.fpnotebook.com/Prevent/Epi/TstSnstvty.htm http://sphweb.bumc.bu.edu/otlt/MPH-Modules/ EP/EP713_Screening/EP713_Screening5.html#positiveandneg ativepredictivevalue Thorner and Remein. Principlesand Procedures in the Evaluation of Screening for Disease, US Department HEW, Public Health Monograph No. 67, 1961