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PANDEMIC PREPAREDNESS AND ETHICAL
CONSIDERATIONS(SARI)
MODERATOR-DR LILY
PRESENTER-DR SUMIT SEHGAL
• Importance of pandemic (or disaster) preparedness
• How the context of triage may change during a pandemic (or
other disaster)
• Human rights framework
• Create a triage considerations to be used during a pandemic (or
disaster) using five ethical principles
|
Learning objectives
Pandemic (or disasters) can easily overwhelm health
systems
• Demand may exceed available ICU resources:
– i.e. number of patients with respiratory failure
requiring MV may exceed available resources.
• The triage principle of “first come, first served”
that guides triage decisions into critical care units
during non-pandemic times no longer suffice.
Challenge: to whom should ventilator be given?
PREPARE AND BE READY
Principles of pandemic preparedness plans
• Preparedness enables the public and health systems
better respond to a pandemic or disaster.
• Created by an interdisciplinary team (e.g. health
ministries, clinicians, administrators, managers,
logisticians, pharmacists, engineers, ethicists, etc.).
• Early public engagement is essential to set priorities
with stakeholders from civil society.
• Maintenance of transparency and fairness is essential to
avoid chaos and fear.
Resources can become exhausted very quickly. Think of
your wider source of resources, not just your unit.
From CHEST, 2014, consensus statement.
Plan for a surge• Targets set on surge continuum.
• Situational awareness of larger health care system.
• Logistics (i.e. patient flow and distribution, evacuation).
• Staff preparation and organization.
• Value chain supply/continuity of operations.
• Legal considerations.
Plan for a
surge
Take action early – conserve, substitute, adapt, reuse.
Pandemic preparedness in
resource-constrained settings● Enhance surveillance systems and reporting.
● Emphasize preventative interventions:
– e.g. vaccination of high risk groups.
● Create partnerships with local and international partners prior to
event with goal to plan for training and support.
● Equip clinicians with evidence-based triage and treatment
protocols from WHO/MOHFW to mitigate need for critical
care.
Pandemic preparedness in
resource-constrained settings
● Strengthen basic health care facilities and delivery at
all levels.
● Build on local expertise and services:
– e.g. if adult or surgical ICU available, then build on this to accommodate
children.
● If none available, develop minimum level of critical
care to be provided at higher level hospital:
– create processes that can be applied to patients most likely to benefit
– e.g. use NIV or bubble CPAP if ventilators are limited.
ETHICS DURING PANDEMICS
● All human beings are born free and equal in
dignity and rights:
– right to freedom from cruel, inhumane or
degrading treatment or punishments
– right to freedom of movement and residence
– right to freedom from arbitrary detention
– right to health.
Human rights framework (1/2)
International obligation for all nations to promote and protect the health
of their civilians, especially by facilitating access to basic health care
services
Striking a balance between individual and collective good can be
challenging, especially under conditions of scientific uncertainty and
• International law allows restrictions on individual
freedoms for the public good (i.e. when public
health is threatened).
• Governments, health ministries and public health
agencies make restrictions based on:
– public health necessity
– reasonableness
– proportionality
– justice.
– trust
crisis.
Human rights framework (2/2)
Equity and health (1/2)
● Inequities are differences in health that are
unnecessary, avoidable, unfair and unjust.
● Do not discriminate based on:
– age
– gender
– race
– ethnicity
– religion
– political affiliation
– social or economic status.
Equity and health (2/2)
• Fair distribution of benefits and burdens.
• In some circumstances, distribution of benefits and
burdens according to individual or group may be
considered fair:
– e.g. it may be equitable to give preference to those
worst off such as the poorest, sickest, or most
vulnerable
– e.g. vaccines or post-exposure prophylaxis for health
care workers.
Ethical principles
● Commonly accepted and justified during public
health emergencies.
● Aim is to save the greatest numbers of lives:
- meaningful independent survival rather than vegetative
state.
● Less priority to patients who are less likely to
recover or sicker.
Principle of utility
Challenge: is there a triage tool that can quickly predict which patient
has lowest chance of short-term survival?
● Aim is to refine principle of utility by considering
the number of life-years saved in addition to lives
saved.
● If two patients have same short-term survival, but
● Then priority would be given to healthier patient to
save more life-years.
Principle of maximum life years saved
one has severe comorbid
disease that limits long
term survival
one is healthy
● Also known as fair innings or intergenerational
equity principles.
● Aim is to give each individual an equal opportunity
to live through the various phases of life.
● Priority is given to younger patients relative to
older patients.
youth. May be considered social worth criterion.
Principle of life cycle
This may be considered discriminatory against older
people, conflict with cultural values prioritizing age over
Caution from WHO about life cycle principle
• Everyone is entitled to some “normal span” of life
years.
• Younger individuals receive priority because they have
had fewer opportunities to live through life’s stages.
• Notion of equality to individuals’ whole lifetime
experiences rather than just to their current
situation.
• Any age-based prioritization should rely on broad life
stages.
Principles of first come first served
and random (lottery) selection
• “If there is no relative difference between
patients, then each should have an equal chance
to receive life-saving treatment.”
• Ensures procedural fairness and equitable access
and can be practically implemented:
– may promote trust, avoids discrimination
– applicable to paediatric population.
Caution: may unfairly disadvantage those who cannot access hospitals
quickly.
Use of triage protocol:
CHEST consensus statement 2014
• The uniform triage process should be prepared
beforehand, publically vetted and widely
disseminated.
• If resources become scarce despite all efforts of
augmentation, activate the uniform triage
process.
• The uniform triage process should be activated
by regional authority with legal protection and
situational awareness.
• CHEST consensus statement does not recommend a certain
tool, but highlights important principles:
– identify critical care triage officer/team to lead triage to
take burden off treating clinicians
– use of a triage protocol is superior to clinical judgment
alone.
– create inclusion criteria for ICU admission.
http://www.chestnet.org/Guidelines-and-Resources/Guidelines-and-Consensus-Statements/CHEST-
Guidelines
Example of triage tool (2/4)• Consider exclusion for patients with > 90% risk of death and
patients with short life expectancy (< 1 year).
• Give opportunity for appeals (deviation from protocol) and re-
evaluation after 48–72 hours.
• There is no triage tool that satisfactorily predicts survival in
children.
• Include paediatric experts as much as possible in planning
and triage process.
Sequential Organ Failure Assessment (SOFA) score
• SOFA has been proposed as a physiologic score to be used as a
mortality prediction model in adults:
– higher score associated with worse outcome
– early study showed that score > 11 associated with > 95%
mortality, but follow up studies not as conclusive.
Caution: SOFA score does not always differentiate between survivors
and non-survivors across all critically ill patients.
Sequential Organ Failure Assessment (SOFA) score
● SOFA can not be used in children because it is not
validated in children.
● In general, mortality rates are lower for critically ill
children and prediction scores are less reliable in
predicting death except in some small groups of
children (i.e. out of hospital arrests).
What affects our decisions?
Summary
• Pandemic preparedness should entail surge capacity response, public engagement,
and health system strengthening. A uniform triage process should be activated only
when resources are overwhelmed.
• During a pandemic or other mass disaster, the need for critical care services can
overwhelm available resources and triage decisions may need to be made on how to
prioritize patients.
• Five ethical principles that can guide triage tools include: the principles of utility,
maximum life-years saved, first come first served, random selection, and life cycle.
• Public engagement in pandemic preparedness is essential to develop a prioritization
strategy that is fair, transparent and builds trust.
Se
• REFERENCES
• https://www.who.int/ethics/pub lications/infectious-disease-
outbreaks/en/
• The following website has information for preparedness and readiness
guidance and tools.
• https://www.who.int/emergencies/diseases/novel-coronavirus-2019
• https://www.who.int/emergencies/diseases/novel-coronavirus-2019/technical-
guidance
• http://www.chestnet.org/Guidelines-and-Resources/Guidelines- and-Consensus-
Statements/CHEST-Guidelines
THANKYOU

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Sari

  • 1. PANDEMIC PREPAREDNESS AND ETHICAL CONSIDERATIONS(SARI) MODERATOR-DR LILY PRESENTER-DR SUMIT SEHGAL
  • 2. • Importance of pandemic (or disaster) preparedness • How the context of triage may change during a pandemic (or other disaster) • Human rights framework • Create a triage considerations to be used during a pandemic (or disaster) using five ethical principles | Learning objectives
  • 3. Pandemic (or disasters) can easily overwhelm health systems • Demand may exceed available ICU resources: – i.e. number of patients with respiratory failure requiring MV may exceed available resources. • The triage principle of “first come, first served” that guides triage decisions into critical care units during non-pandemic times no longer suffice. Challenge: to whom should ventilator be given?
  • 5. Principles of pandemic preparedness plans • Preparedness enables the public and health systems better respond to a pandemic or disaster. • Created by an interdisciplinary team (e.g. health ministries, clinicians, administrators, managers, logisticians, pharmacists, engineers, ethicists, etc.). • Early public engagement is essential to set priorities with stakeholders from civil society. • Maintenance of transparency and fairness is essential to avoid chaos and fear.
  • 6. Resources can become exhausted very quickly. Think of your wider source of resources, not just your unit. From CHEST, 2014, consensus statement.
  • 7. Plan for a surge• Targets set on surge continuum. • Situational awareness of larger health care system. • Logistics (i.e. patient flow and distribution, evacuation). • Staff preparation and organization. • Value chain supply/continuity of operations. • Legal considerations.
  • 8. Plan for a surge Take action early – conserve, substitute, adapt, reuse.
  • 9. Pandemic preparedness in resource-constrained settings● Enhance surveillance systems and reporting. ● Emphasize preventative interventions: – e.g. vaccination of high risk groups. ● Create partnerships with local and international partners prior to event with goal to plan for training and support. ● Equip clinicians with evidence-based triage and treatment protocols from WHO/MOHFW to mitigate need for critical care.
  • 10. Pandemic preparedness in resource-constrained settings ● Strengthen basic health care facilities and delivery at all levels. ● Build on local expertise and services: – e.g. if adult or surgical ICU available, then build on this to accommodate children. ● If none available, develop minimum level of critical care to be provided at higher level hospital: – create processes that can be applied to patients most likely to benefit – e.g. use NIV or bubble CPAP if ventilators are limited.
  • 12. ● All human beings are born free and equal in dignity and rights: – right to freedom from cruel, inhumane or degrading treatment or punishments – right to freedom of movement and residence – right to freedom from arbitrary detention – right to health. Human rights framework (1/2) International obligation for all nations to promote and protect the health of their civilians, especially by facilitating access to basic health care services
  • 13. Striking a balance between individual and collective good can be challenging, especially under conditions of scientific uncertainty and • International law allows restrictions on individual freedoms for the public good (i.e. when public health is threatened). • Governments, health ministries and public health agencies make restrictions based on: – public health necessity – reasonableness – proportionality – justice. – trust crisis. Human rights framework (2/2)
  • 14. Equity and health (1/2) ● Inequities are differences in health that are unnecessary, avoidable, unfair and unjust. ● Do not discriminate based on: – age – gender – race – ethnicity – religion – political affiliation – social or economic status.
  • 15. Equity and health (2/2) • Fair distribution of benefits and burdens. • In some circumstances, distribution of benefits and burdens according to individual or group may be considered fair: – e.g. it may be equitable to give preference to those worst off such as the poorest, sickest, or most vulnerable – e.g. vaccines or post-exposure prophylaxis for health care workers.
  • 17. ● Commonly accepted and justified during public health emergencies. ● Aim is to save the greatest numbers of lives: - meaningful independent survival rather than vegetative state. ● Less priority to patients who are less likely to recover or sicker. Principle of utility Challenge: is there a triage tool that can quickly predict which patient has lowest chance of short-term survival?
  • 18. ● Aim is to refine principle of utility by considering the number of life-years saved in addition to lives saved. ● If two patients have same short-term survival, but ● Then priority would be given to healthier patient to save more life-years. Principle of maximum life years saved one has severe comorbid disease that limits long term survival one is healthy
  • 19. ● Also known as fair innings or intergenerational equity principles. ● Aim is to give each individual an equal opportunity to live through the various phases of life. ● Priority is given to younger patients relative to older patients. youth. May be considered social worth criterion. Principle of life cycle This may be considered discriminatory against older people, conflict with cultural values prioritizing age over
  • 20. Caution from WHO about life cycle principle • Everyone is entitled to some “normal span” of life years. • Younger individuals receive priority because they have had fewer opportunities to live through life’s stages. • Notion of equality to individuals’ whole lifetime experiences rather than just to their current situation. • Any age-based prioritization should rely on broad life stages.
  • 21. Principles of first come first served and random (lottery) selection • “If there is no relative difference between patients, then each should have an equal chance to receive life-saving treatment.” • Ensures procedural fairness and equitable access and can be practically implemented: – may promote trust, avoids discrimination – applicable to paediatric population. Caution: may unfairly disadvantage those who cannot access hospitals quickly.
  • 22. Use of triage protocol: CHEST consensus statement 2014 • The uniform triage process should be prepared beforehand, publically vetted and widely disseminated. • If resources become scarce despite all efforts of augmentation, activate the uniform triage process. • The uniform triage process should be activated by regional authority with legal protection and situational awareness.
  • 23. • CHEST consensus statement does not recommend a certain tool, but highlights important principles: – identify critical care triage officer/team to lead triage to take burden off treating clinicians – use of a triage protocol is superior to clinical judgment alone. – create inclusion criteria for ICU admission. http://www.chestnet.org/Guidelines-and-Resources/Guidelines-and-Consensus-Statements/CHEST- Guidelines
  • 24. Example of triage tool (2/4)• Consider exclusion for patients with > 90% risk of death and patients with short life expectancy (< 1 year). • Give opportunity for appeals (deviation from protocol) and re- evaluation after 48–72 hours. • There is no triage tool that satisfactorily predicts survival in children. • Include paediatric experts as much as possible in planning and triage process.
  • 25. Sequential Organ Failure Assessment (SOFA) score • SOFA has been proposed as a physiologic score to be used as a mortality prediction model in adults: – higher score associated with worse outcome – early study showed that score > 11 associated with > 95% mortality, but follow up studies not as conclusive. Caution: SOFA score does not always differentiate between survivors and non-survivors across all critically ill patients.
  • 26. Sequential Organ Failure Assessment (SOFA) score ● SOFA can not be used in children because it is not validated in children. ● In general, mortality rates are lower for critically ill children and prediction scores are less reliable in predicting death except in some small groups of children (i.e. out of hospital arrests).
  • 27. What affects our decisions?
  • 28. Summary • Pandemic preparedness should entail surge capacity response, public engagement, and health system strengthening. A uniform triage process should be activated only when resources are overwhelmed. • During a pandemic or other mass disaster, the need for critical care services can overwhelm available resources and triage decisions may need to be made on how to prioritize patients. • Five ethical principles that can guide triage tools include: the principles of utility, maximum life-years saved, first come first served, random selection, and life cycle. • Public engagement in pandemic preparedness is essential to develop a prioritization strategy that is fair, transparent and builds trust.
  • 29. Se • REFERENCES • https://www.who.int/ethics/pub lications/infectious-disease- outbreaks/en/ • The following website has information for preparedness and readiness guidance and tools. • https://www.who.int/emergencies/diseases/novel-coronavirus-2019 • https://www.who.int/emergencies/diseases/novel-coronavirus-2019/technical- guidance • http://www.chestnet.org/Guidelines-and-Resources/Guidelines- and-Consensus- Statements/CHEST-Guidelines