San Luis National High School was established in 1998 through Republic Act 8463, which was initiated by Congressman Homobono T. Cezar. It began with 26 students and makeshift classrooms on a 300 square meter property borrowed from the barangay captain. Over the years, support from local government and organizations helped expand the school, which now has 11 classrooms, laboratories, offices and a library serving over 13 teachers. The school aims to fulfill its vision under current principal Edwin Evangelista.