The document discusses the forces driving healthcare transformation including payment reform, consumerism, digitalization, and emerging data sources. It notes the US healthcare system spends the most per capita but is highly fragmented. Digital health startups have an opportunity to engage patients, enable caregivers, and increase efficiencies. However, adoption faces challenges like data security, interoperability, and suboptimal experiences. The document maps the technology vendor landscape and where funding is going in digital health. It concludes with strategies for market development using an Acquire, Defend, Expand framework.