Harriet Beecher Stowe was an American abolitionist and author born in 1811 in Connecticut. She is best known for her novel "Uncle Tom's Cabin", published in 1852, which depicted the harsh reality of slavery and increased public opposition to it in the United States. The novel was a bestseller and had a profound effect on attitudes toward African Americans and slavery prior to the American Civil War. Stowe used her writing to advocate for abolition, women's rights, religious tolerance, and educational reform. She experienced personal tragedy when 3 of her adult children died, including her son Frederick who disappeared without a trace in 1870.