Role of technologies in health innovations. Raimo Sepponen, Aalto University
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Presented in Upgraded Life Festival 31.5.2016 by Raimo Sepponen, Aalto University. http://www.upgradedlifefestival.com/
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Role of technologies in health innovations. Raimo Sepponen, Aalto University
- 1. Role of technologies in health innovations Raimo Sepponen, professor Aalto University
- 2. Role of technologies in health innovations • Case: Magnetic resonance imaging Invented by Paul Lauterbur and Peter Mansfield • Early development stimulated by Raymond Damadian – claimed that malignant tissue may be diagnosed by measuring relaxation time T1
- 3. Raymond Damadian's "Apparatus and method for detecting cancer in tissue."
- 4. FONAR -MRI One of the first whole body MR images About 1978, Fonar-method
- 5. The first MR images in Germany
- 6. Some early truths about MRI (~1980) • The highest usable field strength for human studies is about 0.2 T • MRI will not have any role in routine diagnostics • Imaging times will always be long due to low S/N • With MRI any contrast agents will not be needed or can be used
- 7. But- magnets got stronger
- 8. Optimum field? • 0,15 T – Hammersmith hospital 1985 • 0,35 T – University of San Francisco -1985 • 1,5 T – General Electric 1986 • 2,0 T – Siemens, Philips 1987 • 3, 0 T - 2000 • 7,0 T - 2015 • 11,5 T - 2020
- 9. First image 0,1 T field 0,17 T scanner at HUCS 0,02 T Acutscan 0,04 T Magnaview 0,1 T Mega4 0,1 T Merit 0,22 T Proviev 1981 1982 1984 1989 1979 1992 1 Mmk 5 Mmk 10 Mmk 100 Mmk 150 Mmk OTC NYS 250 Mmk 1st Patent 25 Patents Instru TKK TEKES Instru Akate mia HYKS 1st Thesis 2nd Thesis 4 Thesis Premarket approval
- 10. Open magnet technology – key for the success of MRI-units produced in Finland
- 11. Multiple coils and SENSE Technology
- 12. MRI Today • Over 10 000 units world wide, routine clinical use • Typical fieldstrength 1,5 T , 3,0 T increasing, 7,0 T introduced • Imaging times in the range ms/image • Over 20 different contrast agents available, more under development
- 13. Architecture of human white matter connectivity (Danielle Bassett)
- 14. • Not all problems have a technological answer, but when they do, that is the more lasting solution. • Andy Grove one of the founders of Intel Corporation