REWIND SCIENCE brings you evidence based life extension.
Ageing is a genetically inherited disease with 100% mortality rate. We are in the cusp of cracking the problem of ageing. Science available today can give us 10 to 20 additional healthy years. Before they runs out, we will very likely come across even more breakthroughs, giving us further years on earth.
This slide deck gives you a peep into the fascinating world of practical life extension.
The Bhopal disaster, also referred to as the Bhopal gas tragedy, was a gas leak incident on the night of 2–3 December 1984 at the Union Carbide India Limited (UCIL) pesticide plant in Bhopal, Madhya Pradesh, India. It is considered among the world's worst industrial disasters.
This is a simple PPT which will help you to understand and study about school oral health development and programs. This also include some MCQs at the end which will help you to test yourself and boost your confidence about your capabilities. This also helps you to read the topic in a cut short method.
This is a simple PPT which will help you to understand and study about school oral health development and programs. This also include some MCQs at the end which will help you to test yourself and boost your confidence about your capabilities. This also helps you to read the topic in a cut short method.
This is a simple PPT which will help you to understand and study about school oral health development and programs. This also include some MCQs at the end which will help you to test yourself and boost your confidence about your capabilities. This also helps you to read the topic in a cut short method.
Contents:
Introduction
Definition
Aspects of school health programs
Objectives
Ideal requirements
Advantages
Elements/components
Some school oral health programs
WHO’s global school health initiative
Incremental care
Comprehensive care
Conclusion
The Bhopal disaster, also referred to as the Bhopal gas tragedy, was a gas leak incident on the night of 2–3 December 1984 at the Union Carbide India Limited (UCIL) pesticide plant in Bhopal, Madhya Pradesh, India. It is considered among the world's worst industrial disasters.
This is a simple PPT which will help you to understand and study about school oral health development and programs. This also include some MCQs at the end which will help you to test yourself and boost your confidence about your capabilities. This also helps you to read the topic in a cut short method.
This is a simple PPT which will help you to understand and study about school oral health development and programs. This also include some MCQs at the end which will help you to test yourself and boost your confidence about your capabilities. This also helps you to read the topic in a cut short method.
This is a simple PPT which will help you to understand and study about school oral health development and programs. This also include some MCQs at the end which will help you to test yourself and boost your confidence about your capabilities. This also helps you to read the topic in a cut short method.
Contents:
Introduction
Definition
Aspects of school health programs
Objectives
Ideal requirements
Advantages
Elements/components
Some school oral health programs
WHO’s global school health initiative
Incremental care
Comprehensive care
Conclusion
HPV inefection , HPV disease prevention, Cervical cancer prevention , Cervical cancer treatment, Female cancer , Female cancer prevention , Uterine cancer , Cancer in india
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Feel Great, Lose Weight_ Simple Habits for Lasting and Sustainable Weight Loss-Ahmedboukhatem1
Weight loss isn't a race. It isn't one size fits all. Everyone wants fast results, but when it comes to losing weight with crash diets, what goes down nearly always comes back up. And weight-loss programs designed to fit "everyone" are often too broad and restrictive to fit into the complicated lives of real people.
Drawing on twenty years of experience, Dr. Rangan Chatterjee-BBC personality and author of the bestselling Feel Better in 5-has created a conscious, compassionate, sustainable approach to weight loss that goes far beyond fad diets to find the individual strategies that will work for you.
Packed with quick and easy interventions, this book will help you:
• Understand the effects of what, why, when, where and how we eat
• Discover the root cause of your weight gain
• Nourish your body to lose weight without crash diets or grueling workouts
• Build a toolbox of techniques to help you weigh less while living more
Feel Great, Lose Weight is a new way to look at weight loss-a 360-degree view that goes beyond calories to see the bigger picture, including not just physical but also mental and environmental factors. With Dr. Chatterjee's guidance and encouragement, you'll turn simple and sustainable lifestyle changes into a more energized, confident, and healthier you
It has become increasingly clear that a protein diet plan is far healthier than anything else we have
been offered in the past forty years. But we continue to miss the point. It is not carbohydrates that
are the culprit. What we have to fear is something far more powerful –The Manufactured Food Industry.
Heartfulness Magazine - June 2020 (Volume 5, Issue 6)heartfulness
In our June edition, to inspire us to open up to new horizons in the wake of coronavirus, we hear from Daaji, Bruce Lipton, IchakAdizes, Marilyn Turkovich, Peter Reding, and more. All our authors challenge us to rise above our current preconceptions, so that we become more authentic in order to manifest a better world. Right now our individual and collective choices matter a lot. And in the words of Nelson Mandela, “May your choices reflect your hopes, not your fears.”
Rasamanikya is a excellent preparation in the field of Rasashastra, it is used in various Kushtha Roga, Shwasa, Vicharchika, Bhagandara, Vatarakta, and Phiranga Roga. In this article Preparation& Comparative analytical profile for both Formulationon i.e Rasamanikya prepared by Kushmanda swarasa & Churnodhaka Shodita Haratala. The study aims to provide insights into the comparative efficacy and analytical aspects of these formulations for enhanced therapeutic outcomes.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
HPV inefection , HPV disease prevention, Cervical cancer prevention , Cervical cancer treatment, Female cancer , Female cancer prevention , Uterine cancer , Cancer in india
Anti Ageing , anti ageing spa
Feel Great, Lose Weight_ Simple Habits for Lasting and Sustainable Weight Loss-Ahmedboukhatem1
Weight loss isn't a race. It isn't one size fits all. Everyone wants fast results, but when it comes to losing weight with crash diets, what goes down nearly always comes back up. And weight-loss programs designed to fit "everyone" are often too broad and restrictive to fit into the complicated lives of real people.
Drawing on twenty years of experience, Dr. Rangan Chatterjee-BBC personality and author of the bestselling Feel Better in 5-has created a conscious, compassionate, sustainable approach to weight loss that goes far beyond fad diets to find the individual strategies that will work for you.
Packed with quick and easy interventions, this book will help you:
• Understand the effects of what, why, when, where and how we eat
• Discover the root cause of your weight gain
• Nourish your body to lose weight without crash diets or grueling workouts
• Build a toolbox of techniques to help you weigh less while living more
Feel Great, Lose Weight is a new way to look at weight loss-a 360-degree view that goes beyond calories to see the bigger picture, including not just physical but also mental and environmental factors. With Dr. Chatterjee's guidance and encouragement, you'll turn simple and sustainable lifestyle changes into a more energized, confident, and healthier you
It has become increasingly clear that a protein diet plan is far healthier than anything else we have
been offered in the past forty years. But we continue to miss the point. It is not carbohydrates that
are the culprit. What we have to fear is something far more powerful –The Manufactured Food Industry.
Heartfulness Magazine - June 2020 (Volume 5, Issue 6)heartfulness
In our June edition, to inspire us to open up to new horizons in the wake of coronavirus, we hear from Daaji, Bruce Lipton, IchakAdizes, Marilyn Turkovich, Peter Reding, and more. All our authors challenge us to rise above our current preconceptions, so that we become more authentic in order to manifest a better world. Right now our individual and collective choices matter a lot. And in the words of Nelson Mandela, “May your choices reflect your hopes, not your fears.”
Rasamanikya is a excellent preparation in the field of Rasashastra, it is used in various Kushtha Roga, Shwasa, Vicharchika, Bhagandara, Vatarakta, and Phiranga Roga. In this article Preparation& Comparative analytical profile for both Formulationon i.e Rasamanikya prepared by Kushmanda swarasa & Churnodhaka Shodita Haratala. The study aims to provide insights into the comparative efficacy and analytical aspects of these formulations for enhanced therapeutic outcomes.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
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Muktapishti is a traditional Ayurvedic preparation made from Shoditha Mukta (Purified Pearl), is believed to help regulate thyroid function and reduce symptoms of hyperthyroidism due to its cooling and balancing properties. Clinical evidence on its efficacy remains limited, necessitating further research to validate its therapeutic benefits.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
1. REWIND
S C I E N C E
SARAVANAN BALAKRISHNAN
MINISTER OF MAGIC || REWIND SCIENCE . COM
SBK@LLH.BZ || @SARAVANANORG
E V I D E N C E B A S E D L I F E E X T E N S I O N
2. Scientific research indicates that anti-aging practices can add 25.3 years to longevity
Anti-aging community hopes that more breakthroughs will come along before the first 25 years are up
REALITY CHECK
NATURE
DIGITAL
SCI-FI
HOPE
REWIND MEDICINE
3. LARRY ELLISON
BILL GATES
PAUL ALLEN
PETER THIEL
JEFF BEZOS
LARRY PAGE
SERGEY BRIN
Investors in longevity
research/business
REALITY CHECK - 2
4. WHY WE DIE
LIFE EXTENSION TODAY
WHY TO EXTEND LIFE
EXTEND YOUR IMAGINATION
TOPICS
6. Then may be God now planned for us to take up anti-ageing
WRONG: GOD PLANNED FOR US TO DIE
7. This can’t be true because as a longevity mutation would have wiped out the short-living
WRONG: OLD DIES TO MAKE ROOM FOR YOUNG
Many bristlecone pines live past 5,000 years!
8. Several animals, like the bat (black arrow in the graph above) are exceptions to this rule
WRONG: ANIMALS BURN OUT AT CONSTANT RATE
Reference
9. Air borne and burrowing animals live longer. Terrestrial foragers live less.
RIGHT: RATE OF DEATH IN WILD LONGEVITY
Reference
10. Because salmons with a “get back after spawning” mutation never got a chance to pass on their genes
RED SALMONS DIE AFTER SPAWNING
11. Any mutation that helped us to be healthy after ~40 was never passed on
IN THE WILD, HUMANS WERE DYING AT ~40
12. That’s why it has been so difficult to pin it down till now
AGEING IS SEVERAL THINGS
15. It has 100% mortality rate
AGEING IS AN INHERITED DISEASE
16. Customizing the diet reverses many age related declines
FOOD IS THE FIRST DRUG
Peter Attia, with Gary Taub, are
proposing that the type of food
we eat is the main cause of
the obesity epidemic
Cynthia Kenyon did pioneering
research to show caloric restriction
can reliably extend longevity
17. It is the most reliable, and best understood, life extension tool
EXERCISE IS STILL THE KING
Dr Doug McGuff has
developed a “12 minutes,
once a week” resistance
training protocol
18. With age, body loses efficiency in extracting nutrition from food
NUTRITION SUPPLEMENTS
Dr Andrew Weil, pioneer in integrative medicineHenry Osiecki had written the first ever
University course on using nutrition for
managing cancer
19. Produce fitness and vitality from the Inside by reactivating the “Youth Software”
TOP UP THE HORMONES TO YOUTHFUL LEVELS
Suzanne Somers, 64 years old in this
picture, brought age-extension
revolution to imagination of the
masses with her several books,
including the most popular “Ageless”
20. Already feasible: Lab made body parts, re-grown finger tips and muscles, skin cells that become eyes…
REGENERATIVE MEDICINE
Suzanne Somers, 64 years old in this
picture, brought age-extension
revolution to imagination of the
masses with her several books,
including the most popular “Ageless”
Way back in 1999, Anthony
Atala made the first bladder in
his lab, using patient’s own
stem cells. It is functioning
normally even today.
21. Customize the treatment to suit the genes. Or customize the genes to match the expectation
GENETIC PROFILING AND GENE THERAPY
Sofia Loren is 80 years old in this picture.
She anti-aged before anti-ageing.
22. Anti-ageing is the ultimate self-improvement program. Super-mind in a super-canister is the ultimate objective
LIMITLESS MIND
23. In the foreseeable future, certain looks can come only through cosmetic procedures
ADD ON: COSMETIC PROCEDURES
Valeria Lukyanova, an Ukranian singer/model,
is often called the “real life Barbie”
24. ANTI-AGING
WORKS FROM
THE INSIDE OUT
YOU GET FITTER,
HEALTHIER,
SMARTER THAN
YOUR PEERS,
POSSIBLY RICHER.
SIMPLY BECAUSE
THEY ARE
STANDING STILL.
32. MORE MONEY || MORE FREEDOM || LESS
RESPONSIBILITY || MORE FRIENDS || MORE
WISDOM || MORE COURAGE || MORE STABLE
BRAIN || MORE HAPPINESS
LESS HEALTH . LESS ENERGY . LESS SEX . NO FUTURE
A T 6 0+ , Y O U H A V E
33. BECAUSE YOU ARE WISER AND RICHER NOW, YOUR
SECOND CHANCE AT LIFE WILL BE BETTER THAN THE FIRST
43. First 1,000 years old will probably be only 5-10 years younger than first 150 years old (Aubrey de Grey)
YOU MIGHT REACH “LONGEVITY ESCAPE VELOCITY”
reference
44. If your wealth grows at 10% per annum, in 20 years, you will be 8x richer than when you started
YOU MAY BECOME VERY RICH
45. World will be much richer when older people are productive
AFFLUENCE LIKE WE NEVER SAW
46. When Governments eventually wake up and tax them, will the ultra-rich move to a space colony?
WINNERS WILL WIN VERY BIG
47. When technology makes age reversal possible, will you take a second chance at looking good naked
BEAUTY AND FITNESS
48. Will you still need a sexy body
IF SOFTWARE BECOMES THE COMPANION
49. Only problem with this loony prediction is it’s backed by rock-solid logic
YEAR 2045: WHO NEEDS A BODY