Liquid biopsy, a non-invasive diagnostic breakthrough, revolutionizes disease detection, especially in cancer, by analyzing circulating tumor DNA in bodily fluids. As this technology evolves, comprehensive market insights are crucial.
14 technologies that will shape the future of cancer careMpower Medical Inc
The document discusses 14 technologies that will shape the future of cancer care, including fluid biopsy, which extracts cancer cells from blood samples; real-time cancer diagnostics using devices like the "iKnife" surgical tool; and artificial intelligence to design personalized therapy based on a patient's genetic profile and other factors. It also covers precision surgery using robotic tools, embedded sensors to remotely monitor patients, and social networks to help patients cope with treatment side effects. These technologies aim to revolutionize cancer prevention, diagnosis, treatment, and long-term patient care and support.
The document summarizes the work and goals of OncoPlex Diagnostics, a biotechnology company that uses mass spectrometry and liquid tissue technology to develop cancer diagnostic assays. It thanks various mentors and colleagues for their support of the author's internship. OncoPlex aims to establish standardized protein profiling as the standard for personalized cancer treatment by overcoming challenges such as physician education. The marketing department seeks to increase awareness of OncoPlex's technology by creating deliverables like sales sheets and letters for physicians.
The document summarizes the work and goals of OncoPlex Diagnostics, a biotechnology company that uses mass spectrometry and liquid tissue technology to develop cancer diagnostic assays. It thanks various mentors and colleagues for their support of the author's internship. OncoPlex aims to establish standardized protein profiling as the standard for personalized cancer treatment by overcoming challenges such as physician education and product differentiation. The marketing department seeks to increase awareness of OncoPlex's technology by creating deliverables like sales sheets and letters for physicians.
Oncology drug development faces challenges in demonstrating treatment "value" beyond just clinical efficacy. As cancer treatment shifts to a model of chronic disease management, stakeholders increasingly demand evidence that new drugs provide overall pharmacoeconomic benefits and improved quality of life. The emergence of value-based medicine will require redefining clinical trials to generate appropriate data on a drug's overall worth from multiple perspectives, including patients, clinicians, payers and society.
Cancer targeted therapy market & clinical insight 2015KuicK Research
“Cancer Targeted Therapy Market & Clinical Insight” Report Highlight:
Introduction & Categorization of Cancer Targeted Therapies
Mechanism of Cancer Targeted Tyrosine Kinase, Vaccines, Oncogenes Inhibitors, Monoclonal Antibodies
Cancer Targeted Therapy Clinical Pipeline by Company, Indication & Phase
Clinical Insight on More Than 1200 Cancer Targeted Therapies in Pipeline
Clinical Insight & Patent Analysis of Marketed Cancer Targeted Therapies
Global Cancer Targeted Therapeutics Market Dynamics
Future Prospects of Cancer Targeted Therapies
India Cancer Diagnostics Market: Size, Share, and In-Depth Competitive Analys...Kumar Satyam
According to the TechSci Research report, “India Cancer Diagnostics Market –Industry Size, Share, Trends, Competition Forecast & Opportunities, 2028,” the India Cancer Diagnostics Market stood at USD 571.03 billion in 2022 and is anticipated to grow with a CAGR of 7.36% in the forecast period, 2024-2028. Awareness among individuals regarding cancer diagnostics has led to favorable market conditions for the India Cancer Diagnostics market. Several factors contribute to the growth of various cancer diagnostics products, including advancements in technology, government initiatives, and increased healthcare investments.
Market Dynamics
Rising Incidence of Cancer
In 2022, the projected number of new cancer cases in India was 1,461,427, with a crude incidence rate of 100.4 per 100,000 individuals. Approximately one in nine people in India is expected to face a cancer diagnosis during their lifetime. Notably, lung cancer ranked highest among males, while breast cancer held the top spot for females. Within childhood cancers (0-14 years), lymphoid leukemia emerged as the predominant site, accounting for 29.2% in boys and 24.2% in girls. Looking ahead, an estimated 12.8% increase in cancer incidence by 2025 is expected compared to 2020.
Observational research can impact clinical decision making for cancer treatment by providing real-world evidence to complement randomized controlled trials, which have limitations. Observational studies capture long-term outcomes of various treatments in everyday practice. However, their findings are more susceptible to bias. To strengthen observational research, standards are needed for electronic health data collection and reporting, while prioritizing patient privacy and rigorous methodologies. With these improvements, observational data can better inform estimates of cancer progression and treatment effects.
14 technologies that will shape the future of cancer careMpower Medical Inc
The document discusses 14 technologies that will shape the future of cancer care, including fluid biopsy, which extracts cancer cells from blood samples; real-time cancer diagnostics using devices like the "iKnife" surgical tool; and artificial intelligence to design personalized therapy based on a patient's genetic profile and other factors. It also covers precision surgery using robotic tools, embedded sensors to remotely monitor patients, and social networks to help patients cope with treatment side effects. These technologies aim to revolutionize cancer prevention, diagnosis, treatment, and long-term patient care and support.
The document summarizes the work and goals of OncoPlex Diagnostics, a biotechnology company that uses mass spectrometry and liquid tissue technology to develop cancer diagnostic assays. It thanks various mentors and colleagues for their support of the author's internship. OncoPlex aims to establish standardized protein profiling as the standard for personalized cancer treatment by overcoming challenges such as physician education. The marketing department seeks to increase awareness of OncoPlex's technology by creating deliverables like sales sheets and letters for physicians.
The document summarizes the work and goals of OncoPlex Diagnostics, a biotechnology company that uses mass spectrometry and liquid tissue technology to develop cancer diagnostic assays. It thanks various mentors and colleagues for their support of the author's internship. OncoPlex aims to establish standardized protein profiling as the standard for personalized cancer treatment by overcoming challenges such as physician education and product differentiation. The marketing department seeks to increase awareness of OncoPlex's technology by creating deliverables like sales sheets and letters for physicians.
Oncology drug development faces challenges in demonstrating treatment "value" beyond just clinical efficacy. As cancer treatment shifts to a model of chronic disease management, stakeholders increasingly demand evidence that new drugs provide overall pharmacoeconomic benefits and improved quality of life. The emergence of value-based medicine will require redefining clinical trials to generate appropriate data on a drug's overall worth from multiple perspectives, including patients, clinicians, payers and society.
Cancer targeted therapy market & clinical insight 2015KuicK Research
“Cancer Targeted Therapy Market & Clinical Insight” Report Highlight:
Introduction & Categorization of Cancer Targeted Therapies
Mechanism of Cancer Targeted Tyrosine Kinase, Vaccines, Oncogenes Inhibitors, Monoclonal Antibodies
Cancer Targeted Therapy Clinical Pipeline by Company, Indication & Phase
Clinical Insight on More Than 1200 Cancer Targeted Therapies in Pipeline
Clinical Insight & Patent Analysis of Marketed Cancer Targeted Therapies
Global Cancer Targeted Therapeutics Market Dynamics
Future Prospects of Cancer Targeted Therapies
India Cancer Diagnostics Market: Size, Share, and In-Depth Competitive Analys...Kumar Satyam
According to the TechSci Research report, “India Cancer Diagnostics Market –Industry Size, Share, Trends, Competition Forecast & Opportunities, 2028,” the India Cancer Diagnostics Market stood at USD 571.03 billion in 2022 and is anticipated to grow with a CAGR of 7.36% in the forecast period, 2024-2028. Awareness among individuals regarding cancer diagnostics has led to favorable market conditions for the India Cancer Diagnostics market. Several factors contribute to the growth of various cancer diagnostics products, including advancements in technology, government initiatives, and increased healthcare investments.
Market Dynamics
Rising Incidence of Cancer
In 2022, the projected number of new cancer cases in India was 1,461,427, with a crude incidence rate of 100.4 per 100,000 individuals. Approximately one in nine people in India is expected to face a cancer diagnosis during their lifetime. Notably, lung cancer ranked highest among males, while breast cancer held the top spot for females. Within childhood cancers (0-14 years), lymphoid leukemia emerged as the predominant site, accounting for 29.2% in boys and 24.2% in girls. Looking ahead, an estimated 12.8% increase in cancer incidence by 2025 is expected compared to 2020.
Observational research can impact clinical decision making for cancer treatment by providing real-world evidence to complement randomized controlled trials, which have limitations. Observational studies capture long-term outcomes of various treatments in everyday practice. However, their findings are more susceptible to bias. To strengthen observational research, standards are needed for electronic health data collection and reporting, while prioritizing patient privacy and rigorous methodologies. With these improvements, observational data can better inform estimates of cancer progression and treatment effects.
Global cancer angiogenesis inhibitors market & clinical pipeline insightRajesh Sarma
“Global Cancer Angiogenesis Inhibitors Market & Clinical Pipeline Insight” Report Highlights:
Angiogenesis Inhibitors: Introduction & Need in Cancer Therapy
Modulators & Mechanism of Angiogenesis
Classification of Angiogenesis Inhibitors
Metronomic Therapy - A Recent Advancement in Anti-Angiogenesis Therapy
Global Cancer Angiogenesis Inhibitors Clinical Pipeline by Company, Indication & Phase
Global Cancer Angiogenesis Inhibitors Clinical Pipeline: 146 Drugs
Marketed Cancer Angiogenesis Inhibitors Drugs: 11 Drugs
Global cancer angiogenesis inhibitors market & clinical pipeline insightRajesh Sarma
“Global Cancer Angiogenesis Inhibitors Market & Clinical Pipeline Insight” Report Highlights:
Angiogenesis Inhibitors: Introduction & Need in Cancer Therapy
Modulators & Mechanism of Angiogenesis
Classification of Angiogenesis Inhibitors
Metronomic Therapy - A Recent Advancement in Anti-Angiogenesis Therapy
Global Cancer Angiogenesis Inhibitors Clinical Pipeline by Company, Indication & Phase
Global Cancer Angiogenesis Inhibitors Clinical Pipeline: 146 Drugs
Marketed Cancer Angiogenesis Inhibitors Drugs: 11 Drugs
Radiodermatitis Market: Size, Share, and In-Depth Competitive Analysis Toward...Kumar Satyam
According to the TechSci Research report, "Radiodermatitis Market – Global Industry Size, Share, Trends, Competition Forecast & Opportunities, 2028," the global radiodermatitis market was valued at USD 472.35 million in 2022. It is anticipated to grow at a CAGR of 3.14% during the forecast period from 2024 to 2028. Radiodermatitis is a painful and common side effect of radiation therapy, affecting cancer patients worldwide. The increasing incidence of cancer, advancements in radiation therapy techniques, and a greater focus on improving patient quality of life are significant factors driving the growth of the radiodermatitis market.
Radiodermatitis Market: Size, Share, and In-Depth Competitive Analysis Toward...Kumar Satyam
According to the TechSci Research report, "Radiodermatitis Market – Global Industry Size, Share, Trends, Competition Forecast & Opportunities, 2028," the global radiodermatitis market was valued at USD 472.35 million in 2022. It is anticipated to grow at a CAGR of 3.14% during the forecast period from 2024 to 2028. Radiodermatitis is a painful and common side effect of radiation therapy, affecting cancer patients worldwide. The increasing incidence of cancer, advancements in radiation therapy techniques, and a greater focus on improving patient quality of life are significant factors driving the growth of the radiodermatitis market.
India Molecular Diagnostics Market: Unveiling Competition, Size, and Robust G...Kumar Satyam
According to the TechSci Research report titled “India Molecular Diagnostics Market - Industry Size, Share, Trends, Competition Forecast & Opportunities, 2029,” the India Molecular Diagnostics Market was valued at USD 920.05 million in 2023 and is projected to grow at a CAGR of 8.15% during the forecast period from 2025 to 2029. This robust growth can be attributed to several factors, including the increasing prevalence of infectious diseases and genetic disorders, rising awareness and acceptance of personalized medicine and companion diagnostics, and significant advancements in molecular techniques. Additionally, improvements in healthcare infrastructure, increased healthcare expenditure, and growing demand for early and accurate disease diagnosis are also stimulating market growth. Government initiatives promoting precision medicine and genetic testing further contribute to the market's expansion.
Recent Trends in the India Molecular Diagnostics Market
Technological Advancements
The field of molecular diagnostics is evolving rapidly, with significant technological advancements enhancing diagnostic accuracy and efficiency. Techniques such as next-generation sequencing (NGS) and polymerase chain reaction (PCR) are at the forefront of this transformation. NGS allows for comprehensive genetic analysis, enabling the detection of mutations and variations associated with various diseases, including cancers and inherited disorders. PCR, known for its sensitivity and specificity, is widely used for detecting infectious agents and genetic mutations.
Revolutionizing Pathology The Impact of Digital Pathology and IHC-PRS.pdfihc-prs
In the realm of modern healthcare, the convergence of technology and medicine continues to reshape traditional practices. One such evolution is the integration of digital pathology alongside advanced techniques like Immunohistochemistry Pathology Reporting System (IHC-PRS).
Global liquid biopsy market opportunity & technology outlook 2020Rajesh Sarma
Global Liquid Biopsy Market Opportunity & Technology Outlook 2020 provides an overview of the liquid biopsy market. Liquid biopsy is a non-invasive method that analyzes blood or other bodily fluids to detect biomarkers associated with cancer and other diseases. It has three main techniques - analysis of circulating tumor cells, cell-free tumor DNA, and exosomes. Next generation sequencing is also used to analyze genomic and proteomic sequences from tumor cells captured in liquid biopsies. The report examines the clinical uses and advantages of liquid biopsy compared to traditional tissue biopsy for various cancer types and other indications. It also discusses market drivers and trends, as well as challenges, for the growing liquid biopsy industry.
Advanced Renal Cell Carcinoma Market report also sheds light on the supply chains and the changes in the trends of the upstream raw materials and downstream distributors.
This document discusses barriers to the development and approval of targeted cancer therapies and companion diagnostics. It identifies key challenges such as identifying meaningful molecular targets, developing diagnostic tests, evaluating tests and therapies together, and administrative coordination between companies and regulatory agencies. The document proposes a "targeted development and approval" policy to facilitate accelerated development and approval of targeted therapies used with companion diagnostics. It outlines criteria for this policy, including that the diagnostic assay must demonstrate analytical validity and the therapy shows evidence the target population clinically benefits.
Pharmaceutical Industry's Role in Advancing Precision MedicineClinosolIndia
The pharmaceutical industry plays a pivotal role in driving advancements in precision medicine, a revolutionary approach that tailors medical treatment to individual patient characteristics. By leveraging cutting-edge technologies, conducting innovative research, and collaborating with diverse stakeholders, the pharmaceutical sector contributes significantly to the development and implementation of precision medicine, ushering in a new era of personalized healthcare.
The 10 Most Impactful Leaders in Life Science.pdfTHECIOWORLD
This edition features a handful of The Most Impactful Leaders in Life Science that are leading us into a better future
Read More: https://thecioworld.com/the-10-most-impactful-leaders-in-life-science-september2023/
Patient-Generated Data for Cancer Treatment and ManagementTommy Snitz
Research poster created by myself and Matthew Villarreal while we were students of The University of Texas at Austin's Health Informatics and Health IT Program.
Looks into the benefits and challenges of using patient-generated data in cancer treatment and management
This white paper discusses the need for collaboration across stakeholders in oncology care to define value and access to cancer therapies. It notes increasing drug development costs and the need for value-based medicine to provide both enhanced outcomes and lower costs. Real-world evidence from data on patient outcomes is important for evaluating value and informing decisions by regulators, payers and other stakeholders. Accountable care organizations and a shift to more patient-centered, value-based models in the US and globally are changing expectations and incentives around oncology drug development.
Stratified medicine uses biomarkers to classify patients into subgroups for clinical trials and treatment. This requires closer integration of diagnostic and therapeutic development. Only a few companies have both diagnostic and therapeutic capabilities, so partnerships are common. There is uncertainty around who funds biomarker discovery and validation, with options including spin-offs, government programs, in-house pharma efforts, and pharma partnerships. Stratified medicine increases demand for biomarkers and companion diagnostics but also complexity across development processes.
Patient engagement in clinical trials Martin Kelly
The document discusses improving patient engagement in clinical trials through digital methods. Only 2-5% of cancer patients currently participate in clinical trials. The top 3 solutions identified to engage patients were: 1) a clinical trial finder for patients to inform them of available trials, 2) virtual clinical trials conducted entirely online, and 3) tools to personalize clinical trials to individual patient needs/preferences. The document reviews several companies providing these types of solutions and proposes an experiment partnering with a CRO to test if a digital intervention increases patient enrollment and retention in a clinical trial compared to a control group without a digital intervention.
Cancer targeted therapy market & clinical insight 2015KuicK Research
“Cancer Targeted Therapy Market & Clinical Insight” Report Highlight:
Introduction & Categorization of Cancer Targeted Therapies
Mechanism of Cancer Targeted Tyrosine Kinase, Vaccines, Oncogenes Inhibitors, Monoclonal Antibodies
Cancer Targeted Therapy Clinical Pipeline by Company, Indication & Phase
Clinical Insight on More Than 1200 Cancer Targeted Therapies in Pipeline
Clinical Insight & Patent Analysis of Marketed Cancer Targeted Therapies
Global Cancer Targeted Therapeutics Market Dynamics
Future Prospects of Cancer Targeted Therapies
The maturation of genomic technologies has enabled new
discoveries in disease pathogenesis as well as new approaches to patient care.
In pediatric oncology, patients may now receive individualized genomic analysis to identify molecular aberrations of relevance for diagnosis and/or treatment.
Several recent clinical studies have begun to explore the feasibility and utility of genomics-driven precision medicine.
The coming era of digital therapeutics nrc live - sept 2018Chris Hogg
Thoughts on the past, present and future of digital therapeutics and digital medicines. Presentation for NRC Live Zorgtech Conference in Amsterdam, September 2018.
A complete report of Stratified Medicine as the new approach to deliver healthcare and fully Personalised Medicines. Market and key drivers, industry needs and the Scottish strengths, are all presented in this report.
IMS Health RWES: The Future of Real-World Insights in CancerIMSHealthRWES
The document discusses IMS Health's real-world evidence solutions for cancer, including their cancer data ecosystem. The ecosystem combines various real-world data sources like medical claims, EMR data, and genomic data from over 15 million anonymous cancer patients. It provides comprehensive insights through innovative analytics to help address challenges across the cancer care continuum for clinicians, payers, pharmaceutical companies, patients, and advocacy groups.
Global cancer angiogenesis inhibitors market & clinical pipeline insightRajesh Sarma
“Global Cancer Angiogenesis Inhibitors Market & Clinical Pipeline Insight” Report Highlights:
Angiogenesis Inhibitors: Introduction & Need in Cancer Therapy
Modulators & Mechanism of Angiogenesis
Classification of Angiogenesis Inhibitors
Metronomic Therapy - A Recent Advancement in Anti-Angiogenesis Therapy
Global Cancer Angiogenesis Inhibitors Clinical Pipeline by Company, Indication & Phase
Global Cancer Angiogenesis Inhibitors Clinical Pipeline: 146 Drugs
Marketed Cancer Angiogenesis Inhibitors Drugs: 11 Drugs
Global cancer angiogenesis inhibitors market & clinical pipeline insightRajesh Sarma
“Global Cancer Angiogenesis Inhibitors Market & Clinical Pipeline Insight” Report Highlights:
Angiogenesis Inhibitors: Introduction & Need in Cancer Therapy
Modulators & Mechanism of Angiogenesis
Classification of Angiogenesis Inhibitors
Metronomic Therapy - A Recent Advancement in Anti-Angiogenesis Therapy
Global Cancer Angiogenesis Inhibitors Clinical Pipeline by Company, Indication & Phase
Global Cancer Angiogenesis Inhibitors Clinical Pipeline: 146 Drugs
Marketed Cancer Angiogenesis Inhibitors Drugs: 11 Drugs
Radiodermatitis Market: Size, Share, and In-Depth Competitive Analysis Toward...Kumar Satyam
According to the TechSci Research report, "Radiodermatitis Market – Global Industry Size, Share, Trends, Competition Forecast & Opportunities, 2028," the global radiodermatitis market was valued at USD 472.35 million in 2022. It is anticipated to grow at a CAGR of 3.14% during the forecast period from 2024 to 2028. Radiodermatitis is a painful and common side effect of radiation therapy, affecting cancer patients worldwide. The increasing incidence of cancer, advancements in radiation therapy techniques, and a greater focus on improving patient quality of life are significant factors driving the growth of the radiodermatitis market.
Radiodermatitis Market: Size, Share, and In-Depth Competitive Analysis Toward...Kumar Satyam
According to the TechSci Research report, "Radiodermatitis Market – Global Industry Size, Share, Trends, Competition Forecast & Opportunities, 2028," the global radiodermatitis market was valued at USD 472.35 million in 2022. It is anticipated to grow at a CAGR of 3.14% during the forecast period from 2024 to 2028. Radiodermatitis is a painful and common side effect of radiation therapy, affecting cancer patients worldwide. The increasing incidence of cancer, advancements in radiation therapy techniques, and a greater focus on improving patient quality of life are significant factors driving the growth of the radiodermatitis market.
India Molecular Diagnostics Market: Unveiling Competition, Size, and Robust G...Kumar Satyam
According to the TechSci Research report titled “India Molecular Diagnostics Market - Industry Size, Share, Trends, Competition Forecast & Opportunities, 2029,” the India Molecular Diagnostics Market was valued at USD 920.05 million in 2023 and is projected to grow at a CAGR of 8.15% during the forecast period from 2025 to 2029. This robust growth can be attributed to several factors, including the increasing prevalence of infectious diseases and genetic disorders, rising awareness and acceptance of personalized medicine and companion diagnostics, and significant advancements in molecular techniques. Additionally, improvements in healthcare infrastructure, increased healthcare expenditure, and growing demand for early and accurate disease diagnosis are also stimulating market growth. Government initiatives promoting precision medicine and genetic testing further contribute to the market's expansion.
Recent Trends in the India Molecular Diagnostics Market
Technological Advancements
The field of molecular diagnostics is evolving rapidly, with significant technological advancements enhancing diagnostic accuracy and efficiency. Techniques such as next-generation sequencing (NGS) and polymerase chain reaction (PCR) are at the forefront of this transformation. NGS allows for comprehensive genetic analysis, enabling the detection of mutations and variations associated with various diseases, including cancers and inherited disorders. PCR, known for its sensitivity and specificity, is widely used for detecting infectious agents and genetic mutations.
Revolutionizing Pathology The Impact of Digital Pathology and IHC-PRS.pdfihc-prs
In the realm of modern healthcare, the convergence of technology and medicine continues to reshape traditional practices. One such evolution is the integration of digital pathology alongside advanced techniques like Immunohistochemistry Pathology Reporting System (IHC-PRS).
Global liquid biopsy market opportunity & technology outlook 2020Rajesh Sarma
Global Liquid Biopsy Market Opportunity & Technology Outlook 2020 provides an overview of the liquid biopsy market. Liquid biopsy is a non-invasive method that analyzes blood or other bodily fluids to detect biomarkers associated with cancer and other diseases. It has three main techniques - analysis of circulating tumor cells, cell-free tumor DNA, and exosomes. Next generation sequencing is also used to analyze genomic and proteomic sequences from tumor cells captured in liquid biopsies. The report examines the clinical uses and advantages of liquid biopsy compared to traditional tissue biopsy for various cancer types and other indications. It also discusses market drivers and trends, as well as challenges, for the growing liquid biopsy industry.
Advanced Renal Cell Carcinoma Market report also sheds light on the supply chains and the changes in the trends of the upstream raw materials and downstream distributors.
This document discusses barriers to the development and approval of targeted cancer therapies and companion diagnostics. It identifies key challenges such as identifying meaningful molecular targets, developing diagnostic tests, evaluating tests and therapies together, and administrative coordination between companies and regulatory agencies. The document proposes a "targeted development and approval" policy to facilitate accelerated development and approval of targeted therapies used with companion diagnostics. It outlines criteria for this policy, including that the diagnostic assay must demonstrate analytical validity and the therapy shows evidence the target population clinically benefits.
Pharmaceutical Industry's Role in Advancing Precision MedicineClinosolIndia
The pharmaceutical industry plays a pivotal role in driving advancements in precision medicine, a revolutionary approach that tailors medical treatment to individual patient characteristics. By leveraging cutting-edge technologies, conducting innovative research, and collaborating with diverse stakeholders, the pharmaceutical sector contributes significantly to the development and implementation of precision medicine, ushering in a new era of personalized healthcare.
The 10 Most Impactful Leaders in Life Science.pdfTHECIOWORLD
This edition features a handful of The Most Impactful Leaders in Life Science that are leading us into a better future
Read More: https://thecioworld.com/the-10-most-impactful-leaders-in-life-science-september2023/
Patient-Generated Data for Cancer Treatment and ManagementTommy Snitz
Research poster created by myself and Matthew Villarreal while we were students of The University of Texas at Austin's Health Informatics and Health IT Program.
Looks into the benefits and challenges of using patient-generated data in cancer treatment and management
This white paper discusses the need for collaboration across stakeholders in oncology care to define value and access to cancer therapies. It notes increasing drug development costs and the need for value-based medicine to provide both enhanced outcomes and lower costs. Real-world evidence from data on patient outcomes is important for evaluating value and informing decisions by regulators, payers and other stakeholders. Accountable care organizations and a shift to more patient-centered, value-based models in the US and globally are changing expectations and incentives around oncology drug development.
Stratified medicine uses biomarkers to classify patients into subgroups for clinical trials and treatment. This requires closer integration of diagnostic and therapeutic development. Only a few companies have both diagnostic and therapeutic capabilities, so partnerships are common. There is uncertainty around who funds biomarker discovery and validation, with options including spin-offs, government programs, in-house pharma efforts, and pharma partnerships. Stratified medicine increases demand for biomarkers and companion diagnostics but also complexity across development processes.
Patient engagement in clinical trials Martin Kelly
The document discusses improving patient engagement in clinical trials through digital methods. Only 2-5% of cancer patients currently participate in clinical trials. The top 3 solutions identified to engage patients were: 1) a clinical trial finder for patients to inform them of available trials, 2) virtual clinical trials conducted entirely online, and 3) tools to personalize clinical trials to individual patient needs/preferences. The document reviews several companies providing these types of solutions and proposes an experiment partnering with a CRO to test if a digital intervention increases patient enrollment and retention in a clinical trial compared to a control group without a digital intervention.
Cancer targeted therapy market & clinical insight 2015KuicK Research
“Cancer Targeted Therapy Market & Clinical Insight” Report Highlight:
Introduction & Categorization of Cancer Targeted Therapies
Mechanism of Cancer Targeted Tyrosine Kinase, Vaccines, Oncogenes Inhibitors, Monoclonal Antibodies
Cancer Targeted Therapy Clinical Pipeline by Company, Indication & Phase
Clinical Insight on More Than 1200 Cancer Targeted Therapies in Pipeline
Clinical Insight & Patent Analysis of Marketed Cancer Targeted Therapies
Global Cancer Targeted Therapeutics Market Dynamics
Future Prospects of Cancer Targeted Therapies
The maturation of genomic technologies has enabled new
discoveries in disease pathogenesis as well as new approaches to patient care.
In pediatric oncology, patients may now receive individualized genomic analysis to identify molecular aberrations of relevance for diagnosis and/or treatment.
Several recent clinical studies have begun to explore the feasibility and utility of genomics-driven precision medicine.
The coming era of digital therapeutics nrc live - sept 2018Chris Hogg
Thoughts on the past, present and future of digital therapeutics and digital medicines. Presentation for NRC Live Zorgtech Conference in Amsterdam, September 2018.
A complete report of Stratified Medicine as the new approach to deliver healthcare and fully Personalised Medicines. Market and key drivers, industry needs and the Scottish strengths, are all presented in this report.
IMS Health RWES: The Future of Real-World Insights in CancerIMSHealthRWES
The document discusses IMS Health's real-world evidence solutions for cancer, including their cancer data ecosystem. The ecosystem combines various real-world data sources like medical claims, EMR data, and genomic data from over 15 million anonymous cancer patients. It provides comprehensive insights through innovative analytics to help address challenges across the cancer care continuum for clinicians, payers, pharmaceutical companies, patients, and advocacy groups.
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Exploring the Wonders of Swarm Intelligence.pdfJasper Colin
Imagine millions working together, achieving complex goals without a boss! This isn't a dream, it's swarm intelligence (SI), inspired by nature (think ants & bees!).
How Tech is Transforming Cardiovascular Care.pdfJasper Colin
The cardiovascular information systems (CVIS) market is experiencing a period of exciting growth and innovation. CVIS market is expected to reach a staggering $1.09 billion by 2032.
Your Office Showstopper OR Eyesore: Make your office a place people want to b...Jasper Colin
Forget beige walls and flickering lights!
Companies are creating Instagram-worthy offices with fancy furniture, free snacks, and even ping pong tables.
Why Europeans Don't Want To Play Princess Peach.pdfJasper Colin
European gamers have unique preferences that might surprise you. Our research for a global gaming giant revealed unexpected genre favorites, storytelling styles they crave, and even art styles they prefer.
Buy-SIDE Exercise Caution- U.S. Bank M&A Deals Surge Amidst Earnings Anxiety.pdfJasper Colin
U.S. Bank's surge in M&A activity is tempered by cautious optimism amidst investor concerns over a projected 2.8% earnings dip in 2024, driven by heightened credit costs and commercial real estate delinquencies.
Will Robots Steal Your Jobs? Will Robots Steal Your Jobs? 10 Eye-Opening Work...Jasper Colin
47% of US jobs could be automated in the next 20 years. Check out our latest blog post for 9 more eye-opening stats that will make you rethink the workplace you know.
Local Advanced Lung Cancer: Artificial Intelligence, Synergetics, Complex Sys...Oleg Kshivets
Overall life span (LS) was 1671.7±1721.6 days and cumulative 5YS reached 62.4%, 10 years – 50.4%, 20 years – 44.6%. 94 LCP lived more than 5 years without cancer (LS=2958.6±1723.6 days), 22 – more than 10 years (LS=5571±1841.8 days). 67 LCP died because of LC (LS=471.9±344 days). AT significantly improved 5YS (68% vs. 53.7%) (P=0.028 by log-rank test). Cox modeling displayed that 5YS of LCP significantly depended on: N0-N12, T3-4, blood cell circuit, cell ratio factors (ratio between cancer cells-CC and blood cells subpopulations), LC cell dynamics, recalcification time, heparin tolerance, prothrombin index, protein, AT, procedure type (P=0.000-0.031). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and N0-12 (rank=1), thrombocytes/CC (rank=2), segmented neutrophils/CC (3), eosinophils/CC (4), erythrocytes/CC (5), healthy cells/CC (6), lymphocytes/CC (7), stick neutrophils/CC (8), leucocytes/CC (9), monocytes/CC (10). Correct prediction of 5YS was 100% by neural networks computing (error=0.000; area under ROC curve=1.0).
8 Surprising Reasons To Meditate 40 Minutes A Day That Can Change Your Life.pptxHolistified Wellness
We’re talking about Vedic Meditation, a form of meditation that has been around for at least 5,000 years. Back then, the people who lived in the Indus Valley, now known as India and Pakistan, practised meditation as a fundamental part of daily life. This knowledge that has given us yoga and Ayurveda, was known as Veda, hence the name Vedic. And though there are some written records, the practice has been passed down verbally from generation to generation.
- Video recording of this lecture in English language: https://youtu.be/kqbnxVAZs-0
- Video recording of this lecture in Arabic language: https://youtu.be/SINlygW1Mpc
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
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• Building trust with communities online and offline
• Equipping health professionals to address questions, concerns and health misinformation
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Muktapishti is a traditional Ayurvedic preparation made from Shoditha Mukta (Purified Pearl), is believed to help regulate thyroid function and reduce symptoms of hyperthyroidism due to its cooling and balancing properties. Clinical evidence on its efficacy remains limited, necessitating further research to validate its therapeutic benefits.
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Cell Therapy Expansion and Challenges in Autoimmune DiseaseHealth Advances
There is increasing confidence that cell therapies will soon play a role in the treatment of autoimmune disorders, but the extent of this impact remains to be seen. Early readouts on autologous CAR-Ts in lupus are encouraging, but manufacturing and cost limitations are likely to restrict access to highly refractory patients. Allogeneic CAR-Ts have the potential to broaden access to earlier lines of treatment due to their inherent cost benefits, however they will need to demonstrate comparable or improved efficacy to established modalities.
In addition to infrastructure and capacity constraints, CAR-Ts face a very different risk-benefit dynamic in autoimmune compared to oncology, highlighting the need for tolerable therapies with low adverse event risk. CAR-NK and Treg-based therapies are also being developed in certain autoimmune disorders and may demonstrate favorable safety profiles. Several novel non-cell therapies such as bispecific antibodies, nanobodies, and RNAi drugs, may also offer future alternative competitive solutions with variable value propositions.
Widespread adoption of cell therapies will not only require strong efficacy and safety data, but also adapted pricing and access strategies. At oncology-based price points, CAR-Ts are unlikely to achieve broad market access in autoimmune disorders, with eligible patient populations that are potentially orders of magnitude greater than the number of currently addressable cancer patients. Developers have made strides towards reducing cell therapy COGS while improving manufacturing efficiency, but payors will inevitably restrict access until more sustainable pricing is achieved.
Despite these headwinds, industry leaders and investors remain confident that cell therapies are poised to address significant unmet need in patients suffering from autoimmune disorders. However, the extent of this impact on the treatment landscape remains to be seen, as the industry rapidly approaches an inflection point.
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Revolutionizing The Way Cancer is Detected.pdf
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Revolutionizing The Way Cancer is
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