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Renal Cell
Carcinoma
with Hepatic Metastasis
Introduction
Underlying Disease:
Renal Cell Carcinoma
- Most common type of cancer
- Carcinoma “Karkinos” meaning crab forming
cancer.
Secondary Disease:
-Hepatic Metastasis
-Pneumonia
-Severe Fatty Liver
Introduction
Etiology:
 Smoking
 Obesity
 Hypertension
Pathophysiology:
2 forms of RCC
 Hereditary
 Sporadic
Methodology
Patient Finding
Gathering of Data
Analysis and
Interpretation
Evaluation and
Implication
Recommendation
Subjective
Case: RCC with Hepatic Metastasis
Subject: Mr. Levi O. Fernandez
Age: 58 yrs. old
Civil Status: Married, with 3 sons
Occupation: Former Electrical
Engineer in Japan
Subjective
 Prior to his diagnosis, he experiences
difficulty in urinating, fever, malaise, night
sweats and hypertension.
 He loves eating salty foods, softdrinks and
sweets.
 The foods he doesn’t like are pork and
alcoholic beverages in relation to his
religion as an Adventist.
Objective
Table 1. Quantitative analysis of his 24-hour food recall
Meal No. of
exchanges
CHO (g) PRO (g) FATS (g) ENERGY (kcal)
Rice 10 230 20 - 1000
Meat
Low fat 1 - 8 1 41
Medium fat 1 - 8 6 86
Veg. A 2 3 - - 6
Coffee (free
food)
3 - - - -
TOTAL - 233 36 7 1133
Objective
 Nutrient Adequacy =
Actual Nutrient Intake/Recommended
Nutrient Intake *100
Protein = 36/60(100)
= 60%
Energy = 1133/2320(100)
= 49%
Objective
Food group Recommended servings Actual intake Variance
grains 6-11 6 0-5
vegetables 3-5 2 1-3
fruits 2-4 0 2-4
dairy 2-3 0 2-3
Meat/poultry/fish 2-3 2 0-1
Fats, oils and sweets Use sparingly 5 -
Table 2. Qualitative analysis of his 24-hour food recall
Assessment
 Anthropometric
Patient’s Height and Weight
Pt. Ht. = 5’7
= 67 inches
= 67 inches x 2.54 cm
= 170.18 cm or 1.70 m
Pt. Wt. = 73 kg
Assessment
Desirable Body Weight
DBW = 170.18- 100
= 70.18
= 70.18-7.018 (10% of 70.18)
=63.162 or 63 kg
Assessment
Body Mass Index
BMI = wt. (kg)/ ht. (m)²
= 73 kg/ 2.9
= 25.21
Assessment
Total Energy Allowance
TEA = Activity x DBW
= 35.0 (light) x 63 kg
= 2205 kcal
Assessment
 Biochemical
Clinical Chemistry Laboratory Findings/Result Reference Range Implication
- LDL Cholesterol 4.41 <4.07 HIGH
- Creatinine 135.2 umol/L 53.0-115.0 HIGH
- CHOLE-HDL Ratio 8.28 <4.40 HIGH
Table 3. Significant Laboratory Findings on Blood
Chemistry
HEMATOLOGY Laboratory Findings/Result Reference Range Implication
WBC COUNT 12.20 10^9/L 5.0-10.0 HIGH
Segmenters 0.83% 0.45-0.65 HIGH
Lymphocytes 0.17% 0.20-0.35 LOW
Table 4. Significant Laboratory Findings on Hematology
Urinalysis Laboratory Findings/Result Reference Range Implication
Physical examination
- Color Brown red Yellow
- Transparency cloudy Clear
- Reaction Acidic ACIDIC
Chemical Examination
- Nitrite Positive NEGATIVE BACTERIURIA
Table 5. Significant Laboratory Findings on Urinalysis
Sonography:
Radiological Test:
Final Histophatologic Diagnosis
Kidney, Radical nephrectomy (left):
RENAL CELL CARCINOMA, CLEAR CELL TYPE, FUHRMAN GRADE 2, 8.4
CM IN WIDEST TUMOR DIMENSION.
RENAL CAPSULAR INVASION AND LYMPHOVASCULAR SPACE INVASION
ARE PRESENT.
Plan
 Diet Rx: 2520kcal; C445; P38; F79
2000 mg Na
1600 mg K (41 mEq)
500 mg P (39 mEq)
1200 Ca(60 mEq)
1500 ml fluid
HBV - 2/3 (25.2)
LBV - 1/3 (12.6)
Food group # of
exchanges
Pro Na K Ca P Fluid Cho Fat
Milk
A.powder
½ 4 80 200 180 125 0.3 6 5
Meat ¾ 26 - - - - - - -
Lean Meat
(V-A)
1 - 30 200 15 70 31.0 - 1
Fish
(V-A)
1 ½ - 45 300 22.5 105 46.5 - 1.5
Egg (V-C) ¾ - 82.5 71.25 37.5 86 33.75 - 4.5
Total - 30 237.5 771.25 255 386 111.55 6 12
Food group # of
exchanges
Pro Na K Ca P Fluid Cho Fat
Veg. B1 2 0.6 16 220 60 20 60 3 -
Rice 6 12 - - - - - 118 -
A 4 - 8 240 60 140 300 - -
B 1 - 230 60 20 35 10 - -
Total - 12.6 254 1520 140 195 370 121 -
Total 3 & 4 - 42.6 492 1292 395 581 482 127 12
Food group # of
exchanges
Pro Na K Ca P Fluid Cho Fat
Fruits 3 0 - - - - - - -
A 2 0.8 6 240 20 20 95 20 -
B 1 0.2 2 60 5 5 42 10 -
Sugar 63.6 - - - - - - 384 -
Total - 1.0 8 300 25 25 137 414 -
445 (prescribed)
127 (milk and vegetable and rice)
318 /5 = 63.6 or 64
Food group # of
exchanges
Pro Na K Ca P Fluid Cho Fat
Fat - - - - - - - - -
A 8 0.5 320 16.0 8.0 8.0 8.0 - 4.0
B ½ - 9 22.0 4.0 10.0 9.0 - 2.5
Free foods 4 - - - - - - - 20
Total 3,4,5 and
6
44.1 829 1630 432 624 636 541 74.5
Fat milk 5
Meat 12
17 – 79 = 62 / 5 = 12.4 or 12
Fluid rx = 1500 ml
Inherent 636 ml
864 ml (additional oral fluid)
Na rx = 2000 mg/day
Inherent 829 mg
1171 mg/day (additional oral)
1200 – 432 = 768 = 1 tablet
Intervention
Medical
 Omeprazole, to maintain healing of erosive esophagitis
 Vit. B complex, to treatment To Prevent Vitamin Deficiency Medications
Inherited Disease Marked by Excretion of Sulfur in Urine Medications
 Paracetamol, Taken as required for relief of mild-to-moderate pain or fever.
 Clonidine, treat high blood pressure
 Tramadol, treat moderate to severe pain
 Tranexamic acid, used to control unwanted bleeding
 Ceftriaxone, given before certain types of surgery to prevent infections that may
develop after the operation
 Centrum silver , For Multivitamins and minerals deficiency
 Neobloc, H TN & chronic angina pectoris.
Intervention
Diet
 Maintain A Healthy Body Weight
 Eating more vegetables and fruit
 Potassium and sodium restriction
 fluid
 Low calorie diet
Evaluation
 To check if the patient will follow the
dietary plan, there should be a regular
visit and report about the progress of his
condition. Regular checkup in his
physician is also recommended to have
an update about his health status.
The End.

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Renal Cell Carcinoma with hepatic metastasis

  • 2. Introduction Underlying Disease: Renal Cell Carcinoma - Most common type of cancer - Carcinoma “Karkinos” meaning crab forming cancer. Secondary Disease: -Hepatic Metastasis -Pneumonia -Severe Fatty Liver
  • 3. Introduction Etiology:  Smoking  Obesity  Hypertension Pathophysiology: 2 forms of RCC  Hereditary  Sporadic
  • 4.
  • 5. Methodology Patient Finding Gathering of Data Analysis and Interpretation Evaluation and Implication Recommendation
  • 6. Subjective Case: RCC with Hepatic Metastasis Subject: Mr. Levi O. Fernandez Age: 58 yrs. old Civil Status: Married, with 3 sons Occupation: Former Electrical Engineer in Japan
  • 7. Subjective  Prior to his diagnosis, he experiences difficulty in urinating, fever, malaise, night sweats and hypertension.  He loves eating salty foods, softdrinks and sweets.  The foods he doesn’t like are pork and alcoholic beverages in relation to his religion as an Adventist.
  • 8. Objective Table 1. Quantitative analysis of his 24-hour food recall Meal No. of exchanges CHO (g) PRO (g) FATS (g) ENERGY (kcal) Rice 10 230 20 - 1000 Meat Low fat 1 - 8 1 41 Medium fat 1 - 8 6 86 Veg. A 2 3 - - 6 Coffee (free food) 3 - - - - TOTAL - 233 36 7 1133
  • 9. Objective  Nutrient Adequacy = Actual Nutrient Intake/Recommended Nutrient Intake *100 Protein = 36/60(100) = 60% Energy = 1133/2320(100) = 49%
  • 10. Objective Food group Recommended servings Actual intake Variance grains 6-11 6 0-5 vegetables 3-5 2 1-3 fruits 2-4 0 2-4 dairy 2-3 0 2-3 Meat/poultry/fish 2-3 2 0-1 Fats, oils and sweets Use sparingly 5 - Table 2. Qualitative analysis of his 24-hour food recall
  • 11. Assessment  Anthropometric Patient’s Height and Weight Pt. Ht. = 5’7 = 67 inches = 67 inches x 2.54 cm = 170.18 cm or 1.70 m Pt. Wt. = 73 kg
  • 12. Assessment Desirable Body Weight DBW = 170.18- 100 = 70.18 = 70.18-7.018 (10% of 70.18) =63.162 or 63 kg
  • 13. Assessment Body Mass Index BMI = wt. (kg)/ ht. (m)² = 73 kg/ 2.9 = 25.21
  • 14. Assessment Total Energy Allowance TEA = Activity x DBW = 35.0 (light) x 63 kg = 2205 kcal
  • 15. Assessment  Biochemical Clinical Chemistry Laboratory Findings/Result Reference Range Implication - LDL Cholesterol 4.41 <4.07 HIGH - Creatinine 135.2 umol/L 53.0-115.0 HIGH - CHOLE-HDL Ratio 8.28 <4.40 HIGH Table 3. Significant Laboratory Findings on Blood Chemistry
  • 16. HEMATOLOGY Laboratory Findings/Result Reference Range Implication WBC COUNT 12.20 10^9/L 5.0-10.0 HIGH Segmenters 0.83% 0.45-0.65 HIGH Lymphocytes 0.17% 0.20-0.35 LOW Table 4. Significant Laboratory Findings on Hematology
  • 17. Urinalysis Laboratory Findings/Result Reference Range Implication Physical examination - Color Brown red Yellow - Transparency cloudy Clear - Reaction Acidic ACIDIC Chemical Examination - Nitrite Positive NEGATIVE BACTERIURIA Table 5. Significant Laboratory Findings on Urinalysis
  • 20. Final Histophatologic Diagnosis Kidney, Radical nephrectomy (left): RENAL CELL CARCINOMA, CLEAR CELL TYPE, FUHRMAN GRADE 2, 8.4 CM IN WIDEST TUMOR DIMENSION. RENAL CAPSULAR INVASION AND LYMPHOVASCULAR SPACE INVASION ARE PRESENT.
  • 21. Plan  Diet Rx: 2520kcal; C445; P38; F79 2000 mg Na 1600 mg K (41 mEq) 500 mg P (39 mEq) 1200 Ca(60 mEq) 1500 ml fluid HBV - 2/3 (25.2) LBV - 1/3 (12.6)
  • 22. Food group # of exchanges Pro Na K Ca P Fluid Cho Fat Milk A.powder ½ 4 80 200 180 125 0.3 6 5 Meat ¾ 26 - - - - - - - Lean Meat (V-A) 1 - 30 200 15 70 31.0 - 1 Fish (V-A) 1 ½ - 45 300 22.5 105 46.5 - 1.5 Egg (V-C) ¾ - 82.5 71.25 37.5 86 33.75 - 4.5 Total - 30 237.5 771.25 255 386 111.55 6 12
  • 23. Food group # of exchanges Pro Na K Ca P Fluid Cho Fat Veg. B1 2 0.6 16 220 60 20 60 3 - Rice 6 12 - - - - - 118 - A 4 - 8 240 60 140 300 - - B 1 - 230 60 20 35 10 - - Total - 12.6 254 1520 140 195 370 121 - Total 3 & 4 - 42.6 492 1292 395 581 482 127 12
  • 24. Food group # of exchanges Pro Na K Ca P Fluid Cho Fat Fruits 3 0 - - - - - - - A 2 0.8 6 240 20 20 95 20 - B 1 0.2 2 60 5 5 42 10 - Sugar 63.6 - - - - - - 384 - Total - 1.0 8 300 25 25 137 414 - 445 (prescribed) 127 (milk and vegetable and rice) 318 /5 = 63.6 or 64
  • 25. Food group # of exchanges Pro Na K Ca P Fluid Cho Fat Fat - - - - - - - - - A 8 0.5 320 16.0 8.0 8.0 8.0 - 4.0 B ½ - 9 22.0 4.0 10.0 9.0 - 2.5 Free foods 4 - - - - - - - 20 Total 3,4,5 and 6 44.1 829 1630 432 624 636 541 74.5 Fat milk 5 Meat 12 17 – 79 = 62 / 5 = 12.4 or 12
  • 26. Fluid rx = 1500 ml Inherent 636 ml 864 ml (additional oral fluid) Na rx = 2000 mg/day Inherent 829 mg 1171 mg/day (additional oral) 1200 – 432 = 768 = 1 tablet
  • 27. Intervention Medical  Omeprazole, to maintain healing of erosive esophagitis  Vit. B complex, to treatment To Prevent Vitamin Deficiency Medications Inherited Disease Marked by Excretion of Sulfur in Urine Medications  Paracetamol, Taken as required for relief of mild-to-moderate pain or fever.  Clonidine, treat high blood pressure  Tramadol, treat moderate to severe pain  Tranexamic acid, used to control unwanted bleeding  Ceftriaxone, given before certain types of surgery to prevent infections that may develop after the operation  Centrum silver , For Multivitamins and minerals deficiency  Neobloc, H TN & chronic angina pectoris.
  • 28. Intervention Diet  Maintain A Healthy Body Weight  Eating more vegetables and fruit  Potassium and sodium restriction  fluid  Low calorie diet
  • 29. Evaluation  To check if the patient will follow the dietary plan, there should be a regular visit and report about the progress of his condition. Regular checkup in his physician is also recommended to have an update about his health status.