Remdesivir is a broad-spectrum antiviral drug developed by American biopharmaceutical giant Gilead Sciences. Remdesivir was developed for the treatment of Hepatitis C. Eventually, in the past this drug has been effectively used for the treat SARS coronavirus and MERS coronavirus, and now researchers around the globe are hopeful that this drug stands strong against COVID 19 as well.
2. “
Fauci, the director of the National Institute of
Allergy and Infectious Diseases, announced in an
unpublished from a phase 3 trial that showed
Remdesivir shortened the time to recovery for
patients with COVID-19 from 15 days to 11 days.
2
3. He added he believed Gilead Science’s investigational antiviral
“will be the standard of care” for the novel disease.
Generally, Remdesivir is a broad-spectrum antiviral drug
developed by American biopharmaceutical giant Gilead
Sciences.
3
4. Originally, Remdesivir was developed for the treatment of Hepatitis C. Eventually, in the
past this drug has been effectively used for the treat SARS coronavirus and MERS
coronavirus, and now researchers around the globe are hopeful that this drug stands
strong against COVID 19 as well.
Remdesivir works by interfering with the replication of viruses including SARs and CoV
19 which is responsible for the current pandemic. US Food and Drug Administration
(FDA) granted an ‘emergency use authorization’ for clinicians to use the drug.
4
5. This is a testing times for the medicinal and scientific fraternity from the world and
researchers are furiously trying to develop a drug and save the mankind from deadly virus.
Remdesivir is a ray of hope,a standards of care, not a permanent curebut still can have a
heavy impact on slowing down the pandemic.
But the current situation worldwide is grim. The global pandemic COVID-19 continues to
engulf the worldas the numbers of patients are increasing day by day overloading the
hospitals and shattering the global economy.
5
6. Pharmaffiliates has developed a series of products in the form of Reference standards, Metabolites,
Impurities and Stable Isotopes which might be used as research materials for the treatment of
coronavirus.
Product
Code
Product Name CAS No.
PA 18
1080000
Remdesivir - API 1809249-37-3
PA 18
1081000
(2S,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-
f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-
(hydroxymethyl)tetrahydrofuran-2-carbonitrile
1355049-95-4
6
7. 7
Product Code Product Name CAS No.
PA 18 1081001
(2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-
yl)-5-((benzyloxy)methyl)-3,4-
dihydroxytetrahydrofuran-2-carbonitrile
NA
PA 18 1081002
2-Ethylbutyl ((R)-(4-
nitrophenoxy)(phenoxy)phosphoryl)-D-alaninate
2093124-22-0
PA 18 1081003
2-Ethylbutyl ((R)-((5-nitrohexa-1,5-dien-2-
yl)oxy)(phenoxy)phosphoryl)-L-alaninate
NA
PA 18 1081004 2-Ethylbutyl ((S)-(((Z)-5-nitrohexa-1,3,5-trien-2-
yl)oxy)(phenoxy)phosphoryl)-L-alaninate
NA
8. 8
Product Code Product Name CAS No.
PA 18 1081005
2-Ethylbutyl ((S)-(4-
nitrophenoxy)(phenoxy)phosphoryl)-D-alaninate
2096985-18-9
PA 18 1081006 2-Ethylbutyl (chloro(phenoxy)phosphoryl)-L-alaninate 1355049-92-1
PA 18 1081007
2-Ethylbutyl ((R)-hydroxy(phenoxy)phosphoryl)-L-
alaninate
NA
PA 18 1081008 2-Ethylbutyl D-alaninate 1689993-65-4
9. Product Code Product Name CAS No.
PA 18 1081009
2-Ethylbutyl ((R)-(((3aR,4R,6R,6aR)-6-(4-
aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-6-cyano-2,2-
dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-
yl)methoxy)(phenoxy)phosphoryl)-L-alaninate
NA
PA 18 1081010
2-Ethylbutyl ((S)-(((2R,3S,4R,5S)-5-(4-aminopyrrolo[2,1-
f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-
2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate
NA
PA 18 1081011
2-Ethylbutyl ((S)-(((2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-
f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-
2-yl)methoxy)(phenoxy)phosphoryl)-D-alaninate
2093124-26-4
10. 10
Product Code Product Name CAS No.
PA 18 1081012
2-Ethylbutyl ((R)-(((2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-
f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-
2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate
1911578-75-0
PA 18 1081013 2-Ethylbutyl (hydroxy(phenoxy)phosphoryl)-L-alaninate NA
PA 18 1081014
((S)-(((2R,3S,4R,5R)-5-(4-Aminopyrrolo[2,1-
f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-
2-yl)methoxy)(phenoxy)phosphoryl)-L-alanine
NA
PA 18 1081015 2-Ethylbutyl L-alaninate 946565-74-8
11. 11
Product Code Product Name CAS No.
PA 18 1081012
2-Ethylbutyl ((R)-(((2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-
f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-
2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate
1911578-75-0
Remdesivir is readily available with Pharmaffiliates for research and quality
control purpose.
Pharmaffiliates is an Indian Research Organization with operation in more than
65 countries. We are an ISO 9001, 17025 Guide 34, DSIR and USFDA approved
firm.