2. Review the initial assessment of patient in
respiratory distress
Review management of specific causes of
respiratory distress
Upper airway obstruction
Lower airway obstruction
Lung tissue disease
Disordered control of breathing
Objectives
3. During a busy night, you get the following page:
FYI: Sally, a 2 year old
with PNA had a desat to
88% while on 4L NC.
What do you do next? What initial management steps
would you take?
4. .
How do you initially
assess a patient in
respiratory distress?
5. Rapid assessment
Quickly determine severity of respiratory condition and stabilize
child
Respiratory distress can quickly lead to cardiac compromise
Airway
Support or open airway with jaw thrust
Suction and position patient
Breathing
Provide high concentration oxygen
Bag mask ventilation
Prepare for intubation
Administer medication ie albuterol, epinephrine
Circulation
Establish vascular access: IV/IO
Initial Assesment
6. History and Physical Exam
History
Trauma
Change in voice
Onset of symptoms
Associated symptoms
Exposures
Underlying medical
conditions
Physical Exam
Mental status
Position of comfort
Nasal flaring
Accessory muscle use
Respiratory rate and
pattern
Auscultation for abnormal
breath sounds
8. Pulse oximetry
May be difficult in agitated patient
May be falsely decreased in very anemic patients
Imaging
Chest X Ray
Consider in patients with focal lung findings or respiratory
distress of a unknown etiology
Soft tissue radiograph of lateral neck
May identify a retropharyngeal abscess or radiopaque foreign
body
Labs
ABG/VBG
Chemistry: calculate anion gap
Urine toxicology and glucose if patient has altered
mental status
Initial studies
14. Your intern calls you from the bedside of
Jonathan, a 2 year old with Pompe’s
disease who is BiPAP dependent
overnight with settings of 18/5 and a
backup rate of 18. Over the past few
hours, he has had an increase in his
oxygen requirement from an FiO2 of 21 to
40% and has spiked to 39.2. What steps
do you take to evaluate and manage him
overnight?
Case 2
15. Etiologies of lung tissue disease
Infectious pneumonia
Aspiration pneumonitis
Non-cardiogenic pulmonary edema (ARDS)
Cardiogenic pulmonary edema (ARDS)
Consider positive expiratory pressure (CPAP,
BiPAP or mechanical ventilation with PEEP)
if hypoxemia is refractory to high
concentrations of oxygen
Lung Tissue Disease
16. Abnormal respiratory pattern produces inadequate
minute ventilation
Altered level of consciousness
Elevated intracranial pressure
Cushing’s triad
Poisoning or drug overdose
Administer specific antidote if available
Hyperammonemia
Metabolic acidosis
Neuromuscular disease
Restrictive lung disease => atelectasis, chronic pulmonary
insufficiency, respiratory failure
Support oxygenation and ventilation while treating the
underlying problem
Disordered Control of Breathing
17. The initial assessment of a patient in
respiratory distress should be rapid and
focused on quickly determining the
severity of respiratory distress and need
for emergent interventions
Specific causes of respiratory distress can
be categorized as upper and lower airway
obstruction, lung tissue disease and
disordered control of breathing and require
specific interventions
Take Home Points
18. Albisett, M. Pathogenesis and clinical manifestations
of venous thrombosis and thromboembolism in
infants and children. June 2010. UpToDate.
Bailey, P. Oxygen delivery systems for infants,
children and adults. May 2010. UpToDate.
Ralston, M.et. al. Pediatric Advanced Life Support
Provider Manual. 2006. American Heart
Association.
Sherman, S.C. and Schindlbeck, M. When is venous
blood gas analysis enough? Emerg Med 38(12):44-
48, 2006
Simons, F. Anaphylaxis: Rapid recognition and
treatment. September 2010. UpToDate.
Weiner, D. Emergent evaluation of acute respiratory
distress in children. May 2010. UpToDate.
References
Editor's Notes
Respiratory distress:
characterized by signs of increased work of breathing
stridor
wheezing
tachypnea and retractions
abnormal pattern of respirations
Respiratory distress may be due to:
an attempt to improve minute ventilation in response to hypoxemia or hypercarbia
disordered control of ventilation such as…
respiratory depression from opioid overdose or head injury
respiratory stimulation from metabolic acidosis, salicylate overdose, or hyperammonemia.
Promptly assess the patient to elicit additional important information:
such as the duration of the desaturation,
her general appearance and mental status,
other signs of respiratory distress such as tachypnea, use of accessory muscles, grunting or flaring
If the patient is still hypoxic, what can you do to quickly correct the hypoxia?
increase the flow of the nasal cannula OR
switch to a new delivery device such as a simple face mask
While nasal cannulas can deliver up to 6L/min, flow rates greater than 4L/min are irritating to the nares and therefore switching to a simple face mask may be better tolerated)
Optimize the patient’s positioning and
Suction away secretions, should they be present
Consider a non-rebreather face mask with an increased flow or CPAP
Call for backup (such as a supervising resident or hospitalist)
Consider a trial of albuterol if wheezing is present
Once the patient is stabilized, it may be helpful to obtain a new chest x ray to evaluate for worsening pneumonia or development of an effusion that may have contributed to her acute decompensation.
Stop here. Have group suggest at least two ways they assess patients in respiratory distress. Answers on next slide.
The initial assessment of a child in respiratory distress should be rapid and quickly determine if patient needs emergent interventions and rule out life threatening conditions.
A brief history should be collected initially which should include these important points:
A more detailed history can be collected once the child is stabilized
When auscultating, listen for:
wheezes
crackles
pleural rub
prolonged expiration
decreased breath sounds
transmitted upper airway sounds
Stop here. Have the group suggest two studies they would like to get for a patient in respiratory distress. Answers on the next slide.
Advantages of VBG include less pain to the patient and ability to draw concurrently with other labs
A normal venous pH, pCO2, and HCO3 rules out severe acid base abnormalities
A venous pH of > 7.25 predicts an arterial pH of > 7.2 in 98% of cases
(Conversely, a venous pH of < 7 predicts an arterial pH of < 7.2 in 98% of cases)
A venous pCO2 of > 45 mm Hg is predictive of an arterial pCO2 of > 50 mm Hb
Venous blood gasses do not allow adequate determination of the arterial concentration of oxgyen (paO2) and is not as useful to quantify oxygen delivery to target tissues
Stop here. Have the group suggest three life threatening conditions. Answers on the next slide.
Croup
Symptoms:
barking cough
stridor
retractions
Treatment:
Oral or IM dexamethasone
Oxygen
Keep NPO
Nebulized racemic epinephrine with observation for at least 2 hours after treatment
Anaphylaxis
Symptoms:
Stridor or wheezing
Dizziness
Vomiting or diarrhea
Hives or facial swelling
Treatment:
IM/IV epinephrine
Albuterol (if bronchospasm is present)
Treat hypotension
Diphenhydramine
Ranitidine
Methylprednisolone
Assisted ventilation for patients with lower airway obstruction should be at a slow rate with adequate expiratory time to decrease the risk of air trapping and complications with high airway pressure including pneumothorax, gastric distension, regurgitation and aspiration.
Patients with neuromuscular disorders and dependence on ventilatory support are at increased risk for development of pneumonia due to their underlying restrictive lung disease and propensity to develop atelectasis. In this patient, the new fever and significant increase in his oxygen requirement is suggestive of pneumonia therefore management should include…
Obtaining a chest x ray to evaluate for the presence of an infiltrate
If an infiltrate is present, antibiotics should be started promptly
Anti-pyretics should be given.
Obtain a venous blood gas to evaluate for retention of carbon dioxide
Adjustment of the patient’s BiPAP based on the results of the blood gas should include:
review of prior blood gasses
consultation with the team primarily responsible for managing his BiPAP (likely Pulmonology)
If the patient continues to worsen, transferring the patient to the PICU may be appropriate.
For more information regarding specific etiologies of lung tissue disease:
Infectious pneumonia
Symptoms: fever, tachypnea, hypoxemia, increased work of breathing, crackles or decreased breath sounds
Management:
Ancillary testing: ABG/VBG, CXR, viral studies, CBC, BCx
Antibiotics to treat gram + organisms, consider macrolide coverage
Albuterol if wheezing
Reduce temperature if febrile
Aspiration pneumonia
Symptoms: coughing or gagging associated with feeding, more common in children with abnormal neurologic status
Management
Respiratory support and antibiotics if infiltrate is present on CXR
Non-cardiogenic pulmonary edema (ARDS)
Symptoms: pulmonary or systemic insult to the alveolar-capillary unit with release of inflammatory mediators
Management
Correction of hypoxemia
Intubate if hypoxemia is refractory to high inspired oxygen concentrations
Cardiogenic pulmonary edema
Symptoms: fluid accumulation in the lung interstitium due to elevated pulmonary capillary pressure
Management
Ventilatory support
Support cardiovascular function
Disordered control of breathing can be due to elevation of intracranial pressure or depressed level of consciousness due to CNS infection, seizures, metabolic disorders, poisoning or drug overdose.