This study quantified the water savings from controlling the invasive water hyacinth plant in the Vaalharts Irrigation Scheme in South Africa. Water hyacinth leads to substantial water losses through high evapotranspiration rates, reducing the available water for productive irrigation agriculture. The study estimated the annual water loss from three levels of water hyacinth coverage at a weir using evapotranspiration ratios. This lost water was valued between R9 billion to R500 million based on the average production value of irrigation water. The results highlight the need to control invasive plants that threaten economically important water resources and sustainability.