Cold-EEZE is a zinc gluconate glycine lozenge that is clinically proven to reduce the duration of the common cold by 42%. Its formula allows for sustained release of zinc ions over an extended period of time compared to other oral zinc remedies like Zicam RapidMelts. This extended release provides zinc ions interference with rhinovirus reproduction for a longer duration between doses. Cold-EEZE efficacy has been demonstrated in peer-reviewed studies.