This document lists 21 publications by Dr. Regina A. Dressendörfer, including original papers published in scientific journals and abstracts presented at conferences. The publications cover a range of topics including the development of non-isotopic immunoassays for hormones like cortisol, cyclic GMP, and growth hormone, as well as the application of these assays to evaluate hormone levels in various clinical contexts and populations.
The power point presentation describes development of Ru(II) complexes for cancer treatment. The presentation is prepared based on three review articles published in Chemical Society Reviews on 2017 and 2018:
(1)Chem. Soc. Rev., 2017,46,5771
(2)Chem. Soc. Rev., 2017,46,7706
(3)Chem. Soc. Rev., 2018,47, 909-928.
DOC1 - National Toxicology Program - Toxicology and Carcinogenesis 4 MIToxiColaOrg
Este es el único estudio realizado en seres vivos para evaluar el potencial toxicológico y cancerígeno del compuesto 4-Metilidimadazol que se encuentra en el colorante Caramelo IV usado por Coca Cola, las bebidas de Cola y otros productos. Fue realizado por el Programa Nacional de Toxicología del Servicio de Salud Pública de los Estados Unidos en 2007. Para evaluar el riesgo que pueden presentar para la salud humana diversos compuestos, se realizan estudios en animales, considerando que si hay un efecto negativo en su salud, estos compuestos no deberían ser consumidos por las personas. El estudio se realizó en ratas y ratones durante dos años y su conclusión fue: "Concluimos que el 4-Metilidimadazol causa cáncer de pulmón en ratones machos y hembras. El 4-Metilidimazol se puede asociar también con el desarrollo de leucemia en ratas hembras".
The power point presentation describes development of Ru(II) complexes for cancer treatment. The presentation is prepared based on three review articles published in Chemical Society Reviews on 2017 and 2018:
(1)Chem. Soc. Rev., 2017,46,5771
(2)Chem. Soc. Rev., 2017,46,7706
(3)Chem. Soc. Rev., 2018,47, 909-928.
DOC1 - National Toxicology Program - Toxicology and Carcinogenesis 4 MIToxiColaOrg
Este es el único estudio realizado en seres vivos para evaluar el potencial toxicológico y cancerígeno del compuesto 4-Metilidimadazol que se encuentra en el colorante Caramelo IV usado por Coca Cola, las bebidas de Cola y otros productos. Fue realizado por el Programa Nacional de Toxicología del Servicio de Salud Pública de los Estados Unidos en 2007. Para evaluar el riesgo que pueden presentar para la salud humana diversos compuestos, se realizan estudios en animales, considerando que si hay un efecto negativo en su salud, estos compuestos no deberían ser consumidos por las personas. El estudio se realizó en ratas y ratones durante dos años y su conclusión fue: "Concluimos que el 4-Metilidimadazol causa cáncer de pulmón en ratones machos y hembras. El 4-Metilidimazol se puede asociar también con el desarrollo de leucemia en ratas hembras".
DOC1 - National Toxicology Program - Toxicology and Carcinogenesis 4 MI
Publikations-Liste final
1. 1
List of Publications, Regina A. Dressendörfer, PhD
Original Papers
1. Dressendörfer, R.A., C. Kirschbaum, W. Rohde, F. Stahl, C.J. Strasburger.: Synthesis
of a cortisol-biotin conjugate and evaluation as a tracer in an immunoassay for salivary
cortisol measurement. J. Steroid Biochem. Molec. Biol. 43 (7):683-692 (1992)
2. Drummer, C., M. Heer, R.A.Dressendörfer, C.J. Strasburger, R. Gerzer: Reduced
natriuresis during weightlessness. Clin. Investig. 71 :678-686 (1993)
3. Strasburger, C.J., K. Schriever, R.A. Dressendörfer: Comparison of commercially
available immunoassay kits for the determination of IGFBP-3. Kinisches Laboratorium
40:741-747 (1994)
4. Strasburger, C.J., K. Schriever, R.A. Dressendörfer: Vergleich der kommerziell
verfügbaren Immunoassays zur Bestimmung von IGFBP-3. Klinisches Laboratorium
40:749-755 (1994)
5. Dressendörfer, R.A., J.-M. Heim, R. Gerzer, C.J. Strasburger: A non-isotopic
immunoassay for Guanosine 3':5' :-cyclic monophosphate using a cyclic GMP-biotin
conjugate as tracer. J. Immunoassay 16(1) 37-53 (1995)
6. Kiess, W., A.Meidert, Dressendörfer, R.A., Schriever, K., Kessler, U., König, A,
Schwarz, H.P., Strasburger, C.J.: Salivary cortisol levels throughout childhood and
adolescence: Relation with age, pubertal stage, and weight. Pediatric Research 37 (4):
502-506 (1995)
7. Strasburger, C.J., Z. Wu, C.-D. Pflaum, R.A. Dressendörfer: Immunofunctional assay
of human growth hormone (hGH) in serum: a possible consensus for quantitative hGH
measurement. J.Clin.Endocrinol. Metab. 81: 2613-2620 (1996)
8. Eisen, C., C. Meyer, R. Dressendörfer, C. Strasburger, H. Decker, M. Wehling: Biotin-
Iabelled and photoactivatable aldosterone and progesterone derivates as ligands for
affinity chromatography, fluorescence immunoassays and photoaffinity labelling. Eur. J.
Biochem. 237: 514-518 (1996)
2. 2
Abstracts
1. Dressendörfer, R., C. Kirschbaum, W.G. Wood, C.J. Strasburger: Flexible end-point
determination in a salivary cortisol assay using a cortisol-biotin conjugate as tracer. J. Clin.
Chem. Clin. Biochem. 28:653 (1990)
2. Strasburger, C.J., R. Dressendörfer, W.G. Wood: Biotinylated cortisol: A potent and
stable tracer in immunoassays for cortisol determination. J. Clin. Chem. Clin. Biochem.
28:663 (1990)
3. Strasburger, C.J., R. Dressendörfer, C. Kirschbaum, W. Rohde, F. Stahl, W.G. Wood:
Cortisol- biotin conjugate as a potent and stable tracer in an immunoassay for salivary
cortisol measurement. Abstracts of the 72nd Endocrine Society Annual Meeting, Abstract
No. 848, Atlanta GA (1990)
4. Reiss, I., R. Dressendörfer, K. Lechner, O.A. Müller, C.J. Strasburger: Heterogeneity of
results in hGH determination by immunoassays: impact of antibody selection and
arrangement. Acta Endocrinologica (Kbh) Suppl.1, 124:233 (1991)
5. Strasburger, C.J., R. Dressendörfer, A. Galli, P. Gellerfors, C.D. Pflaum, I. Reiss:
Pituitary and recombinant forms of human growth hormone (hGH) have discrepant binding
patterns to antibodies and the circulating hGH binding serum protein. 73rd Annual Meeting
of the Endocrine Society, Washington D.C., Abstract NO.1547 (1991)
6. Kiess, W., A. Meidert, C.J. Strasburger, R.A. Dressendörfer, H.P. Schwarz: Salivary
cortisol levels throughout childhood and adolescence: normal values. 31 st Annual
Meeting European Society of Pediatric Endocrinology, Zaragossa, Spain, 6.-9. 9. 1992,
Abstract No. 124, Hormone Research 37 (Suppl. 4): 32 (1992)
7. Pflaum, C.-D., R.A. Dressendörfer, C.J. Strasburger: Human growth hormone binding
protein (hGH-BP) in urine. Acta Endokrinologica 126 (SuppI.4):29 (1992)
8. Strasburger, C.J., C.-D. Pflaum, R. Dressendörfer: Demonstration and initial
characterisation of human growth hormone binding protein (hGH-BP) in urine. Abstract No.
P-08.01.113, Nineth International Congress of Endocrinology, Nice, France, 30.8.-5.9.
(1992)
3. 3
9. Kiess, W., A. Meidert, C.J. Strasburger, R. Dressendörfer, H.P. Schwarz: Cortisol im
Speichel: Normalwerte von der Geburt bis zum Erwachsenenalter. Korrelation der
Speichelkortisolkonzentration mit der Pubarche / Adrenarche. 88. Jahrestagung der
Deutschen Gesellschaft für Kinderheilkunde, 20.-23.9.1992, Hamburg, Abstract No. 68,
Monatsschrift Kinderheilkunde 140:516 (1992)
10.Pflaum, C.-D., R.A. Dressendörfer, C.J. Strasburger: A nonisotopic solid phase
immunoassay for the determination of human growth hormone binding protein (hGHBP).
Exp. Clin. Endocrinol. 101 (Suppl1 ):44 (1993)
11.Dressendörfer, R.A., S. Löbel, H. Wuthe, B. Glöckner, K. Horn, C.J. Strasburger:
Determination of cortisol in serum: comparison of two 125[1]-labelled and three non-
isotopic immunoassays. Exp. Clin. Endocrinol. 101 (SuppI1):177 (1993)
12.Tschöp, M., R.A. Dressendörfer, C.J. Strasburger: Reliability of saliva sampling devices
for salivary testosterone assays. Exp. Clin. Endocrinol. 101 (SuppI1):178 (1993)
13.Erhardt, S.K., R A. Dressendörfer, I. Reiss, C.J. Strasburger: An immunometric assay for
specific measurement of the 22kD human growth hormone (hGH) form using monoclonal
antibodies (Mabs) of defined epitoope specificity. 75th Annual Meeting of the Endocrine
Society, Las Vegas, NV, Abstract No. 1128 (1993)
14.Strasburger, C.J., C.D. Pflaum, R.A. Dressendörfer, R. Nass: Growth Hormone Binding
Protein (hGHBP) is Elevated in Growth Hormone (hGH) Deficient Adults and Normalizes
under hGH Replacement Therapy. Exp. Clin. Endocrinol. 102 (SuppI1):196 (1994)
15.Strasburger, C.J., R.A. Dressendörfer, P.D.K. Lee: Non-isotopic two-site immunoassay
for IGFBP3. Abstract 11. 348. Growth Regulation 4 (SuppI.1):138 (1994)
16.Tschöp, M., R.A. Dressendörfer, H.M. Behre, E. Nieschlag, C.J. Strasburger:
Measurement of testosterone in saliva made feasable by a sensitive time-resolved
fluorescence immunoassay. Abstract P 1.104, Eur. J. Endocrinol130 (SuppI.2):121 (1994)
4. 4
17.Wu, Z., R.A. Dressendörfer, C.-D. Plaum, C.J. Strasburger: An immunofunctional assay
using human growth hormone (hGH) binding protein for the measurement of hGH levels in
serum. Abstract V44, Exp. Clin. Endocrinol. 103 (Suppl. 1):86 (1995)
18.Wu, Z., R.A. Dressendörfer, C.-D. Plaum, C.J. Strasburger: Immunofunctional
measurement of human growth hormone (hGH) in serum: a possible consensus for
quantitative hGH determination. 77th annual meeting, Washington, The Endocrine Society,
Abstract P1-188 (1995)
19.Tschöp, M., R.A. Dressendörfer, C.M. Behre, E. Nieschlag, C.J. Strasburger: Monitoring
of substitution therapy with testosterone buciclate in hypogonadal men by a time-resolved
fluorescence immunoassay for salivary testosterone. 77th annual meeting, Washington,
The Endocrine Society, Abstract P2-116 (1995)
20.Dressendörfer, R.A., W. Kiess, F. Bidlingmaier, C. Smit, W. Rascher, I. Klug, A. Kistner,
C.J. Strasburger: A time-resolved fluorescence immunoassay for the determination of 17-
Hydroxyprogesterone (17-OHP) in saliva for monitoring of children with congenital adrenal
hyperplasia (CAH). Clin Chem 42:S111 (Abstract No. 067) (1996)
21.Dressendörfer, R.A., K. Schriever, C.J. Strasburger: Neurosurgery or medical treatment
of a pituitary mass? Adaptation of a commercial prolactin kit for decision-making within
thirty minutes. Clin Chem 42:S228 (Abstract No. 553) (1996)