This document provides summaries of 16 research articles related to Niemann-Pick disease type C1 (NPC1). The articles investigate potential biomarkers for early diagnosis of NPC1, examine the urinary excretion and metabolism of drugs used to treat NPC1, identify new potential biomarkers through metabolic profiling, and study the effects of glycosphingolipid storage and treatment on various cells and pathways involved in NPC1 pathogenesis.