PROTEINS
• Proteins arecomplex macromolecules
composed of one or more long chains of
amino acids.
• They play critical roles in virtually all
biological processes, including
• catalysis of biochemical reactions,
• structural support, transport of
molecules, and
• regulation of cellular activities.
3.
CLASSIFICATION
• Owing totheir diverse roles and complex structures, proteins are classified
systematically to better understand their nature and functionality
STRUCTURE
COMPOSITION
4.
COMPOSTION
• Proteins canbe classified into three primary categories based on their
composition:
• Simple Proteins
• Conjugated Proteins
• Derived Proteins
5.
1. Simple Proteins
Homoproteins
consistsolely of amino acids.
Upon hydrolysis, they yield only
amino acids and no other non-
protein components.
exhibit a simple, linear structure
6.
2. Conjugated Proteins
complexproteins that contain non-
amino acid components known as
prosthetic groups, covalently or non-
covalently attached to the polypeptide
chain.
Upon hydrolysis, yield amino acids
and the prosthetic group.
7.
TYPES OF CONJUGATED
PROTEINS
Glycoproteins:Proteins with
carbohydrate groups covalently
attached
• Glycoproteins are proteins
which contain oligosaccharide
(sugar) chains covalently
attached to amino acid side-
chains. PROCESS IS
CALLED
GLYCOSYLATION .
8.
2. Phosphoproteins: Proteinsthat have
phosphate groups attached.
Phosphoproteins are proteins that have a
phosphate group attached
3. Lipoproteins: Proteins bound to lipids.
Lipid-containing proteins are called
lipoproteins. This class includes some of the
blood plasma proteins and also a large number
of membrane proteins.
9.
• Nucleoproteins: Proteinscombined with nucleic
acids.
Nucleoproteins are protein complexes that contain
nucleic acids,
categorized as deoxyribonucleoproteins (DNPs) or
ribonucleoproteins (RNPs) respectively.
• Chromoproteins: Proteins that contain pigmented
prosthetic groups.
The chromo proteins are a heterogeneous group of
conjugated proteins related to each other only in that
they all possess color.
hemoglobin’s
myoglobin’s, and
other heme-containing proteins
cytochromes and
hemerythrins belong to this group.
10.
• Hemoproteins: Proteinscontaining
heme as a prosthetic group.
Hemoglobin contains the prosthetic group
known as heme.
• Flavoproteins: Proteins that contain a
flavin group as a prosthetic group.
• Metalloproteins: Proteins that contain
metal ions as cofactors.
11.
3. Derived Proteins: Derived proteins are
products resulting from the hydrolysis of simple
or conjugated proteins.
• Formed by the breakdown of native proteins
through physical or chemical processes.
• Include smaller peptides and fragments with
altered properties compared to the original
proteins.