Presentation1
•Download as PPT, PDF•
0 likes•151 views
The document discusses engaging various groups such as residents, landowners, young people, volunteers, and ethnic minorities in landscape designations and protected areas in Wales. It provides examples of engagement activities like the Carreglwyd Forest Festival, geocaching at Jubilee Tower, Moel Famau, and Welsh baccalaureate student volunteers helping with an AONB clean-up. It closes with a note of caution.
Report
Share
Report
Share
Recommended
Topics page
This document is an example topic page created by Ms. Hoe on South Africa. It lists keywords, concepts, and people related to the topic for reference. Words include apartheid, boers, afrikaners, township, and dehumanize. Concepts involve dehumanization, peaceful dissent, and civil disobedience. People mentioned are Nelson Mandela, Desmond Tutu, and F.W. de Klerk. Townships and daily life within them regarding access to resources is also noted.
Brockholes slidesfinal
Natural England advises the UK government on designating protected areas and manages some of these areas. They are working to establish an ecological network of protected sites that are larger, more connected, and better able to help wildlife adapt to climate change. Some key programs include Nature Improvement Areas, which provide funding to connect and restore habitats, and marine conservation zones to protect marine environments.
Brockholes slidesfinal
Natural England advises the UK government on designating protected areas and manages some of these areas. They are working to establish an ecological network of protected sites that are larger, more connected, and better able to help wildlife adapt to climate change. Some key programs include Nature Improvement Areas, which provide funding to connect and restore habitats, and marine conservation zones to protect marine environments.
Protected areasnatural solutions
This document provides an agenda for a conference on protected areas. The conference will discuss the importance and value of protected areas globally and in the UK. It will examine challenges and pressures facing protected areas, including those in national parks and landscapes. The conference will also discuss best practices, innovations, and opportunities regarding protected area management. It will feature perspectives on protected areas from UK nature conservation agencies. The document schedules sessions on these topics with multiple speakers as well as questions, breaks, and an annual general meeting for the IUCN National Committee UK.
Iucn
This document discusses United Kingdom protected areas and Areas of Outstanding Natural Beauty (AONBs). It addresses who designates AONBs, the differences between conservation approaches, and how AONBs involve both natural and human factors. Specifically, it notes that AONBs focus on landscape, people, and facilitating natural and human interactions. It also discusses AONB governance models and how the areas fit into protected area categories.
Uk protected areas
The document summarizes protected areas in the UK and provides context on international conventions and targets for protected area coverage. Some key points:
1) The UK has designated over 6,600 Sites of Special Scientific Interest and hundreds of other protected areas covering around 8% of land and inland water.
2) The UK Overseas Territories include very large Marine Protected Areas around places like South Georgia and the Chagos Archipelago.
3) Protected areas must be designed and managed as ecologically coherent networks to effectively conserve biodiversity in the face of environmental change.
Amw iucn260412withoutnotes
The document discusses various pressures and approaches related to national parks and areas of outstanding natural beauty. It mentions development pressures, proposed housing and railway projects, and CAP reform's impact on the environment. It also addresses issues like climate change, landscape-scale connections, bracken control, ecosystem services, and balancing natural beauty with numbers and evidence-based approaches.
Sd hprestnfor iucnconfnxpowerlite
This document discusses landscape-scale conservation and the role of protected areas. It notes that climate change will increase pressure on biodiversity, so protected areas need to be more resilient and help species adapt. Protected areas will remain crucial for conservation by providing refuges for moving species. Landscape-scale conservation should use protected areas as anchors and work to increase habitat diversity, reverse fragmentation, and boost connectivity in surrounding areas. The legal framework of EU directives supports both site-based and broader landscape conservation efforts.
Recommended
Topics page
This document is an example topic page created by Ms. Hoe on South Africa. It lists keywords, concepts, and people related to the topic for reference. Words include apartheid, boers, afrikaners, township, and dehumanize. Concepts involve dehumanization, peaceful dissent, and civil disobedience. People mentioned are Nelson Mandela, Desmond Tutu, and F.W. de Klerk. Townships and daily life within them regarding access to resources is also noted.
Brockholes slidesfinal
Natural England advises the UK government on designating protected areas and manages some of these areas. They are working to establish an ecological network of protected sites that are larger, more connected, and better able to help wildlife adapt to climate change. Some key programs include Nature Improvement Areas, which provide funding to connect and restore habitats, and marine conservation zones to protect marine environments.
Brockholes slidesfinal
Natural England advises the UK government on designating protected areas and manages some of these areas. They are working to establish an ecological network of protected sites that are larger, more connected, and better able to help wildlife adapt to climate change. Some key programs include Nature Improvement Areas, which provide funding to connect and restore habitats, and marine conservation zones to protect marine environments.
Protected areasnatural solutions
This document provides an agenda for a conference on protected areas. The conference will discuss the importance and value of protected areas globally and in the UK. It will examine challenges and pressures facing protected areas, including those in national parks and landscapes. The conference will also discuss best practices, innovations, and opportunities regarding protected area management. It will feature perspectives on protected areas from UK nature conservation agencies. The document schedules sessions on these topics with multiple speakers as well as questions, breaks, and an annual general meeting for the IUCN National Committee UK.
Iucn
This document discusses United Kingdom protected areas and Areas of Outstanding Natural Beauty (AONBs). It addresses who designates AONBs, the differences between conservation approaches, and how AONBs involve both natural and human factors. Specifically, it notes that AONBs focus on landscape, people, and facilitating natural and human interactions. It also discusses AONB governance models and how the areas fit into protected area categories.
Uk protected areas
The document summarizes protected areas in the UK and provides context on international conventions and targets for protected area coverage. Some key points:
1) The UK has designated over 6,600 Sites of Special Scientific Interest and hundreds of other protected areas covering around 8% of land and inland water.
2) The UK Overseas Territories include very large Marine Protected Areas around places like South Georgia and the Chagos Archipelago.
3) Protected areas must be designed and managed as ecologically coherent networks to effectively conserve biodiversity in the face of environmental change.
Amw iucn260412withoutnotes
The document discusses various pressures and approaches related to national parks and areas of outstanding natural beauty. It mentions development pressures, proposed housing and railway projects, and CAP reform's impact on the environment. It also addresses issues like climate change, landscape-scale connections, bracken control, ecosystem services, and balancing natural beauty with numbers and evidence-based approaches.
Sd hprestnfor iucnconfnxpowerlite
This document discusses landscape-scale conservation and the role of protected areas. It notes that climate change will increase pressure on biodiversity, so protected areas need to be more resilient and help species adapt. Protected areas will remain crucial for conservation by providing refuges for moving species. Landscape-scale conservation should use protected areas as anchors and work to increase habitat diversity, reverse fragmentation, and boost connectivity in surrounding areas. The legal framework of EU directives supports both site-based and broader landscape conservation efforts.
Iucnpa apr12 tewfinal
This document discusses biodiversity offsetting as a way to compensate for environmental impacts from development. It proposes establishing a market for conservation credits where developers can purchase credits from protected area receptor sites to offset residual impacts. This would allow for biodiversity gains through funding management of protected areas. Metrics and monitoring systems would be needed to establish conservation credits and assess development impacts and habitat gains. Establishing these biodiversity offsetting programs could generate significant funding for protected areas on a national scale.
Iucn2012
The document summarizes the history and development of Marine Protected Areas (MPAs) in UK waters over the past 30 years. It discusses the evolution from individual sites in the 1980s and 1990s to developing networks of protected areas. The UK now has 96 Special Areas of Conservation designating 5.6% of UK seas, and new Marine Conservation Zones and national MPAs have been designated since 2013. Management of MPAs is challenging and often contentious due to pressures from fisheries. While progress has been made in scale, the designated areas may have limited effectiveness due to industry lobbying and complex feature-based management approaches.
Protareas nattrustiucn confspryor22apr2012
The document discusses categories of protected areas on the National Trust estate in the UK. It notes that the Trust owns 255,000 hectares of land, including 97,000 hectares designated as Sites of Special Scientific Interest. It questions whether some Trust sites meet the criteria for certain protected area categories and explores how to best apply protected area concepts strategically and consider protection outside Trust boundaries.
Hm iucn conf2012eisgeinbkgd
The John Muir Trust is a UK organization that aims to protect and enhance wild land areas. It owns 9 key wild land areas and works with communities to manage land. The Trust defines wild land as large, scenic areas with minimal human development that have ecological and spiritual value. Wild land faces threats from infrastructure like power lines and wind farms. The Trust advocates for stronger protections like new designations and expanded national parks. It discusses challenges around different administrations not having joined-up thinking on environment and development policies. The Trust aims to ensure wild places are valued and protected for future generations.
Mackinnon sandwithiucnu kconferenceapril2012
This document discusses how protected areas can help address global challenges like climate change. It outlines how protected areas store and capture carbon, enhance ecosystem resilience, and provide essential services. The document then discusses how to better design protected area systems to be ecologically representative and well-connected. It also emphasizes the need for improved management capacity, governance, and financing to effectively manage protected areas. The overall message is that protected areas can play a key role in climate change mitigation and adaptation if they are better integrated into land use planning and protected area networks are expanded and better managed.
Mackinnon sandwithiucnu kconferenceapril2012
This document discusses how protected areas can help address global challenges like climate change. It outlines several key ways that protected areas and ecosystems can act as part of the solution:
1) Protected areas can enhance resilience to climate change by storing carbon, capturing carbon dioxide, and protecting ecosystems to buffer climate impacts and maintain essential services.
2) Establishing large, well-connected protected area networks that represent diverse ecosystems can help conserve biodiversity and support climate adaptation and mitigation.
3) Improving protected area management, financing, governance, and participation can help protected areas achieve conservation objectives and be integrated into broader landscape planning to meet global challenges.
Iuc npresentation final
Scottish Natural Heritage published a document about engaging with people in Scotland's protected areas through improved understanding and communications. The director of operations at Scottish Natural Heritage outlined their goals of maintaining high quality and resilient natural landscapes and nature that deliver public value, make Scotland a better place, and contribute to the economy by having more people experience, enjoy and value nature.
Putting natureonthemaplancashire26april
The document discusses the global increase in protected areas from 1,000 in 1962 to over 160,000 in 2010. It explains the IUCN categories for protected areas and governance types, and how the UK currently has incomplete and inaccurate data on protected areas according to these international standards. The Putting Nature on the Map project aims to apply the 2008 IUCN guidelines to identify protected areas in the UK and provide verified data to international databases. Phase 1 developed a handbook interpreting the guidelines for the UK context, and Phase 2 will involve collecting updated protected areas data from agencies and organizations for review against the standards.
Protected areasnatural solutions
This document provides an agenda and overview for a conference on protected areas in the UK and internationally. The conference covers several sessions on topics like the importance and challenges of protected areas globally and in the UK, best practices and innovations, and perspectives from UK nature conservation agencies. It highlights keynote speakers and panels discussing issues such as assigning protected area categories, pressures on national parks, landscape-scale conservation, and marine protected areas. The agenda also includes an annual general meeting for the IUCN National Committee UK to discuss its annual review, elections, finances, and preparations for an upcoming world conservation congress.
Iucn
This document discusses United Kingdom protected areas and Areas of Outstanding Natural Beauty (AONBs). It addresses who designates AONBs, the differences between conservation approaches, and how AONBs involve both natural and human factors. Specifically, it notes that AONBs focus on landscape, people, and facilitating natural and human interactions. It also discusses AONB governance models and how the areas fit into protected area categories.
June 2024 Oncology Cartoons By Dr Kanhu Charan Patro
une 2024 Oncology Cartoons By Dr Kanhu Charan Patro
Pharmacology of 5-hydroxytryptamine and Antagonist
5-hydroxytryptamine or 5-HT or Serotonin is a neurotransmitter that serves a range of roles in the human body. It is sometimes referred to as the happy chemical since it promotes overall well-being and happiness.
It is mostly found in the brain, intestines, and blood platelets.
5-HT is utilised to transport messages between nerve cells, is known to be involved in smooth muscle contraction, and adds to overall well-being and pleasure, among other benefits. 5-HT regulates the body's sleep-wake cycles and internal clock by acting as a precursor to melatonin.
It is hypothesised to regulate hunger, emotions, motor, cognitive, and autonomic processes.
NARCOTICS- POLICY AND PROCEDURES FOR ITS USE
This document outlines policies and procedures for handling narcotic and controlled drugs in NABH accredited hospitals.
How to Control Your Asthma Tips by gokuldas hospital.
Respiratory issues like asthma are the most sensitive issue that is affecting millions worldwide. It hampers the daily activities leaving the body tired and breathless.
The key to a good grip on asthma is proper knowledge and management strategies. Understanding the patient-specific symptoms and carving out an effective treatment likewise is the best way to keep asthma under control.
Ageing, the Elderly, Gerontology and Public Health
Challenges associated with ageing from a public health perspective
Demystifying Fallopian Tube Blockage- Grading the Differences and Implication...
Fallopian tube blockage may cause female infertility. For treatment, herbal medicine Fuyan Pill can be a solution.
STUDIES IN SUPPORT OF SPECIAL POPULATIONS: GERIATRICS E7
Unit 4: MRA 103T Regulatory affairs
This guideline is directed principally toward new Molecular Entities that are
likely to have significant use in the elderly, either because the disease intended
to be treated is characteristically a disease of aging ( e.g., Alzheimer's disease) or
because the population to be treated is known to include substantial numbers of
geriatric patients (e.g., hypertension).
Breast cancer: Post menopausal endocrine therapy
Breast cancer in postmenopausal women with hormone receptor-positive (HR+) status is a common and complex condition that necessitates a multifaceted approach to management. HR+ breast cancer means that the cancer cells grow in response to hormones such as estrogen and progesterone. This subtype is prevalent among postmenopausal women and typically exhibits a more indolent course compared to other forms of breast cancer, which allows for a variety of treatment options.
Diagnosis and Staging
The diagnosis of HR+ breast cancer begins with clinical evaluation, imaging, and biopsy. Imaging modalities such as mammography, ultrasound, and MRI help in assessing the extent of the disease. Histopathological examination and immunohistochemical staining of the biopsy sample confirm the diagnosis and hormone receptor status by identifying the presence of estrogen receptors (ER) and progesterone receptors (PR) on the tumor cells.
Staging involves determining the size of the tumor (T), the involvement of regional lymph nodes (N), and the presence of distant metastasis (M). The American Joint Committee on Cancer (AJCC) staging system is commonly used. Accurate staging is critical as it guides treatment decisions.
Treatment Options
Endocrine Therapy
Endocrine therapy is the cornerstone of treatment for HR+ breast cancer in postmenopausal women. The primary goal is to reduce the levels of estrogen or block its effects on cancer cells. Commonly used agents include:
Selective Estrogen Receptor Modulators (SERMs): Tamoxifen is a SERM that binds to estrogen receptors, blocking estrogen from stimulating breast cancer cells. It is effective but may have side effects such as increased risk of endometrial cancer and thromboembolic events.
Aromatase Inhibitors (AIs): These drugs, including anastrozole, letrozole, and exemestane, lower estrogen levels by inhibiting the aromatase enzyme, which converts androgens to estrogen in peripheral tissues. AIs are generally preferred in postmenopausal women due to their efficacy and safety profile compared to tamoxifen.
Selective Estrogen Receptor Downregulators (SERDs): Fulvestrant is a SERD that degrades estrogen receptors and is used in cases where resistance to other endocrine therapies develops.
Combination Therapies
Combining endocrine therapy with other treatments enhances efficacy. Examples include:
Endocrine Therapy with CDK4/6 Inhibitors: Palbociclib, ribociclib, and abemaciclib are CDK4/6 inhibitors that, when combined with endocrine therapy, significantly improve progression-free survival in advanced HR+ breast cancer.
Endocrine Therapy with mTOR Inhibitors: Everolimus, an mTOR inhibitor, can be added to endocrine therapy for patients who have developed resistance to aromatase inhibitors.
Chemotherapy
Chemotherapy is generally reserved for patients with high-risk features, such as large tumor size, high-grade histology, or extensive lymph node involvement. Regimens often include anthracyclines and taxanes.
“Psychiatry and the Humanities”: An Innovative Course at the University of Mo...
“Psychiatry and the Humanities”: An Innovative Course at the University of Mo...Université de Montréal
“Psychiatry and the Humanities”: An Innovative Course at the University of Montreal Expanding the medical model to embrace the humanities. Link: https://www.psychiatrictimes.com/view/-psychiatry-and-the-humanities-an-innovative-course-at-the-university-of-montrealMore Related Content
More from objass
Iucnpa apr12 tewfinal
This document discusses biodiversity offsetting as a way to compensate for environmental impacts from development. It proposes establishing a market for conservation credits where developers can purchase credits from protected area receptor sites to offset residual impacts. This would allow for biodiversity gains through funding management of protected areas. Metrics and monitoring systems would be needed to establish conservation credits and assess development impacts and habitat gains. Establishing these biodiversity offsetting programs could generate significant funding for protected areas on a national scale.
Iucn2012
The document summarizes the history and development of Marine Protected Areas (MPAs) in UK waters over the past 30 years. It discusses the evolution from individual sites in the 1980s and 1990s to developing networks of protected areas. The UK now has 96 Special Areas of Conservation designating 5.6% of UK seas, and new Marine Conservation Zones and national MPAs have been designated since 2013. Management of MPAs is challenging and often contentious due to pressures from fisheries. While progress has been made in scale, the designated areas may have limited effectiveness due to industry lobbying and complex feature-based management approaches.
Protareas nattrustiucn confspryor22apr2012
The document discusses categories of protected areas on the National Trust estate in the UK. It notes that the Trust owns 255,000 hectares of land, including 97,000 hectares designated as Sites of Special Scientific Interest. It questions whether some Trust sites meet the criteria for certain protected area categories and explores how to best apply protected area concepts strategically and consider protection outside Trust boundaries.
Hm iucn conf2012eisgeinbkgd
The John Muir Trust is a UK organization that aims to protect and enhance wild land areas. It owns 9 key wild land areas and works with communities to manage land. The Trust defines wild land as large, scenic areas with minimal human development that have ecological and spiritual value. Wild land faces threats from infrastructure like power lines and wind farms. The Trust advocates for stronger protections like new designations and expanded national parks. It discusses challenges around different administrations not having joined-up thinking on environment and development policies. The Trust aims to ensure wild places are valued and protected for future generations.
Mackinnon sandwithiucnu kconferenceapril2012
This document discusses how protected areas can help address global challenges like climate change. It outlines how protected areas store and capture carbon, enhance ecosystem resilience, and provide essential services. The document then discusses how to better design protected area systems to be ecologically representative and well-connected. It also emphasizes the need for improved management capacity, governance, and financing to effectively manage protected areas. The overall message is that protected areas can play a key role in climate change mitigation and adaptation if they are better integrated into land use planning and protected area networks are expanded and better managed.
Mackinnon sandwithiucnu kconferenceapril2012
This document discusses how protected areas can help address global challenges like climate change. It outlines several key ways that protected areas and ecosystems can act as part of the solution:
1) Protected areas can enhance resilience to climate change by storing carbon, capturing carbon dioxide, and protecting ecosystems to buffer climate impacts and maintain essential services.
2) Establishing large, well-connected protected area networks that represent diverse ecosystems can help conserve biodiversity and support climate adaptation and mitigation.
3) Improving protected area management, financing, governance, and participation can help protected areas achieve conservation objectives and be integrated into broader landscape planning to meet global challenges.
Iuc npresentation final
Scottish Natural Heritage published a document about engaging with people in Scotland's protected areas through improved understanding and communications. The director of operations at Scottish Natural Heritage outlined their goals of maintaining high quality and resilient natural landscapes and nature that deliver public value, make Scotland a better place, and contribute to the economy by having more people experience, enjoy and value nature.
Putting natureonthemaplancashire26april
The document discusses the global increase in protected areas from 1,000 in 1962 to over 160,000 in 2010. It explains the IUCN categories for protected areas and governance types, and how the UK currently has incomplete and inaccurate data on protected areas according to these international standards. The Putting Nature on the Map project aims to apply the 2008 IUCN guidelines to identify protected areas in the UK and provide verified data to international databases. Phase 1 developed a handbook interpreting the guidelines for the UK context, and Phase 2 will involve collecting updated protected areas data from agencies and organizations for review against the standards.
Protected areasnatural solutions
This document provides an agenda and overview for a conference on protected areas in the UK and internationally. The conference covers several sessions on topics like the importance and challenges of protected areas globally and in the UK, best practices and innovations, and perspectives from UK nature conservation agencies. It highlights keynote speakers and panels discussing issues such as assigning protected area categories, pressures on national parks, landscape-scale conservation, and marine protected areas. The agenda also includes an annual general meeting for the IUCN National Committee UK to discuss its annual review, elections, finances, and preparations for an upcoming world conservation congress.
Iucn
This document discusses United Kingdom protected areas and Areas of Outstanding Natural Beauty (AONBs). It addresses who designates AONBs, the differences between conservation approaches, and how AONBs involve both natural and human factors. Specifically, it notes that AONBs focus on landscape, people, and facilitating natural and human interactions. It also discusses AONB governance models and how the areas fit into protected area categories.
More from objass (10)
Recently uploaded
June 2024 Oncology Cartoons By Dr Kanhu Charan Patro
une 2024 Oncology Cartoons By Dr Kanhu Charan Patro
Pharmacology of 5-hydroxytryptamine and Antagonist
5-hydroxytryptamine or 5-HT or Serotonin is a neurotransmitter that serves a range of roles in the human body. It is sometimes referred to as the happy chemical since it promotes overall well-being and happiness.
It is mostly found in the brain, intestines, and blood platelets.
5-HT is utilised to transport messages between nerve cells, is known to be involved in smooth muscle contraction, and adds to overall well-being and pleasure, among other benefits. 5-HT regulates the body's sleep-wake cycles and internal clock by acting as a precursor to melatonin.
It is hypothesised to regulate hunger, emotions, motor, cognitive, and autonomic processes.
NARCOTICS- POLICY AND PROCEDURES FOR ITS USE
This document outlines policies and procedures for handling narcotic and controlled drugs in NABH accredited hospitals.
How to Control Your Asthma Tips by gokuldas hospital.
Respiratory issues like asthma are the most sensitive issue that is affecting millions worldwide. It hampers the daily activities leaving the body tired and breathless.
The key to a good grip on asthma is proper knowledge and management strategies. Understanding the patient-specific symptoms and carving out an effective treatment likewise is the best way to keep asthma under control.
Ageing, the Elderly, Gerontology and Public Health
Challenges associated with ageing from a public health perspective
Demystifying Fallopian Tube Blockage- Grading the Differences and Implication...
Fallopian tube blockage may cause female infertility. For treatment, herbal medicine Fuyan Pill can be a solution.
STUDIES IN SUPPORT OF SPECIAL POPULATIONS: GERIATRICS E7
Unit 4: MRA 103T Regulatory affairs
This guideline is directed principally toward new Molecular Entities that are
likely to have significant use in the elderly, either because the disease intended
to be treated is characteristically a disease of aging ( e.g., Alzheimer's disease) or
because the population to be treated is known to include substantial numbers of
geriatric patients (e.g., hypertension).
Breast cancer: Post menopausal endocrine therapy
Breast cancer in postmenopausal women with hormone receptor-positive (HR+) status is a common and complex condition that necessitates a multifaceted approach to management. HR+ breast cancer means that the cancer cells grow in response to hormones such as estrogen and progesterone. This subtype is prevalent among postmenopausal women and typically exhibits a more indolent course compared to other forms of breast cancer, which allows for a variety of treatment options.
Diagnosis and Staging
The diagnosis of HR+ breast cancer begins with clinical evaluation, imaging, and biopsy. Imaging modalities such as mammography, ultrasound, and MRI help in assessing the extent of the disease. Histopathological examination and immunohistochemical staining of the biopsy sample confirm the diagnosis and hormone receptor status by identifying the presence of estrogen receptors (ER) and progesterone receptors (PR) on the tumor cells.
Staging involves determining the size of the tumor (T), the involvement of regional lymph nodes (N), and the presence of distant metastasis (M). The American Joint Committee on Cancer (AJCC) staging system is commonly used. Accurate staging is critical as it guides treatment decisions.
Treatment Options
Endocrine Therapy
Endocrine therapy is the cornerstone of treatment for HR+ breast cancer in postmenopausal women. The primary goal is to reduce the levels of estrogen or block its effects on cancer cells. Commonly used agents include:
Selective Estrogen Receptor Modulators (SERMs): Tamoxifen is a SERM that binds to estrogen receptors, blocking estrogen from stimulating breast cancer cells. It is effective but may have side effects such as increased risk of endometrial cancer and thromboembolic events.
Aromatase Inhibitors (AIs): These drugs, including anastrozole, letrozole, and exemestane, lower estrogen levels by inhibiting the aromatase enzyme, which converts androgens to estrogen in peripheral tissues. AIs are generally preferred in postmenopausal women due to their efficacy and safety profile compared to tamoxifen.
Selective Estrogen Receptor Downregulators (SERDs): Fulvestrant is a SERD that degrades estrogen receptors and is used in cases where resistance to other endocrine therapies develops.
Combination Therapies
Combining endocrine therapy with other treatments enhances efficacy. Examples include:
Endocrine Therapy with CDK4/6 Inhibitors: Palbociclib, ribociclib, and abemaciclib are CDK4/6 inhibitors that, when combined with endocrine therapy, significantly improve progression-free survival in advanced HR+ breast cancer.
Endocrine Therapy with mTOR Inhibitors: Everolimus, an mTOR inhibitor, can be added to endocrine therapy for patients who have developed resistance to aromatase inhibitors.
Chemotherapy
Chemotherapy is generally reserved for patients with high-risk features, such as large tumor size, high-grade histology, or extensive lymph node involvement. Regimens often include anthracyclines and taxanes.
“Psychiatry and the Humanities”: An Innovative Course at the University of Mo...
“Psychiatry and the Humanities”: An Innovative Course at the University of Mo...Université de Montréal
“Psychiatry and the Humanities”: An Innovative Course at the University of Montreal Expanding the medical model to embrace the humanities. Link: https://www.psychiatrictimes.com/view/-psychiatry-and-the-humanities-an-innovative-course-at-the-university-of-montrealArtificial Intelligence Symposium (THAIS)
Artificial Intelligence Symposium (THAIS). Parc Taulí. Sabadell
PGx Analysis in VarSeq: A User’s Perspective
Since our release of the PGx capabilities in VarSeq, we’ve had a few months to gather some insights from various use cases. Some users approach PGx workflows by means of array genotyping or what seems to be a growing trend of adding the star allele calling to the existing NGS pipeline for whole genome data. Luckily, both approaches are supported with the VarSeq software platform. The genotyping method being used will also dictate what the scope of the tertiary analysis will be. For example, are your PGx reports a standalone pipeline or would your lab’s goal be to handle a dual-purpose workflow and report on PGx + Diagnostic findings.
The purpose of this webcast is to:
Discuss and demonstrate the approaches with array and NGS genotyping methods for star allele calling to prep for downstream analysis.
Following genotyping, explore alternative tertiary workflow concepts in VarSeq to handle PGx reporting.
Moreover, we will include insights users will need to consider when validating their PGx workflow for all possible star alleles and options you have for automating your PGx analysis for large number of samples. Please join us for a session dedicated to the application of star allele genotyping and subsequent PGx workflows in our VarSeq software.
Medical Quiz ( Online Quiz for API Meet 2024 ).pdf
This quiz was conducted as a promotional event for the 2024 Annual Meet of Kerala Chapter of API.
More than 20 participants took part everyday !
Pune Call Girls 7339748667 AVAILABLE HOT GIRLS AUNTY BOOK NOW
Pune Call Girls 7339748667 AVAILABLE HOT GIRLS AUNTY BOOK NOW
Pollen and Fungal allergy: aeroallergy.pdf
Pollen and Fungal allergy: aeroallergy.pdfChulalongkorn Allergy and Clinical Immunology Research Group
Pollen and Fungal allergy
Presented by Chaloemchai Chumsaengchotsakul, MD.
June 14, 2024Recently uploaded (20)
June 2024 Oncology Cartoons By Dr Kanhu Charan Patro
June 2024 Oncology Cartoons By Dr Kanhu Charan Patro
Pharmacology of 5-hydroxytryptamine and Antagonist
Pharmacology of 5-hydroxytryptamine and Antagonist
How to Control Your Asthma Tips by gokuldas hospital.
How to Control Your Asthma Tips by gokuldas hospital.
Ageing, the Elderly, Gerontology and Public Health
Ageing, the Elderly, Gerontology and Public Health
Demystifying Fallopian Tube Blockage- Grading the Differences and Implication...
Demystifying Fallopian Tube Blockage- Grading the Differences and Implication...
STUDIES IN SUPPORT OF SPECIAL POPULATIONS: GERIATRICS E7
STUDIES IN SUPPORT OF SPECIAL POPULATIONS: GERIATRICS E7
“Psychiatry and the Humanities”: An Innovative Course at the University of Mo...
“Psychiatry and the Humanities”: An Innovative Course at the University of Mo...
Medical Quiz ( Online Quiz for API Meet 2024 ).pdf
Medical Quiz ( Online Quiz for API Meet 2024 ).pdf
Pune Call Girls 7339748667 AVAILABLE HOT GIRLS AUNTY BOOK NOW
Pune Call Girls 7339748667 AVAILABLE HOT GIRLS AUNTY BOOK NOW
Presentation1
- 1. Roger Thomas CEO Countryside Council for Wales
- 2. depend on People Environment shaped by
- 3. depend on Nurt ure People not Environment Pilla g e shaped by
- 4. Landscape designations in Wales -25% of our land area
- 5. Residents Landowners Young People Engagement Volunteers People outside PAs Ethnic Minorities
- 7. Residents Landowners Young People Engagement Volunteers People outside PAs Ethnic Minorities
- 8. Carreglwyd Forest Festival Anglesey AONB
- 9. Residents Landowners Young People Engagement Volunteers People outside PAs Ethnic Minorities
- 12. Residents Landowners Young People Engagement Volunteers People outside PAs Ethnic Minorities
- 13. Jubilee Tower, Moel Famau Young ‘geocachers’ from Newport
- 14. Residents Landowners Young People Engagement Volunteers People outside PAs Ethnic Minorities
- 16. Residents Landowners Young People Engagement Volunteers People outside PAs Ethnic Minorities
- 17. Welsh baccalaureate student volunteers on AONB clean-up
- 18. ……and those whose student days are long past!
- 19. To end on a note of caution…..