This document provides an overview of geriatric medicine and aging from the perspective of PRM (Prof. Ivo Bianchi). It discusses the increasing importance of geriatrics due to population aging. Common aging-related diseases are listed. Peculiarities of aging people are described, including increased need for continuous treatment and remedies that stimulate cells and preserve organ integrity. PRM proposes treatment strategies focused on common age-related diseases and symptoms using PRM remedies. The document also discusses conventional medicine approaches to anti-aging including risks of GH, DHEA and melatonin therapies.
O documento discute várias formas de correção da má-oclusão de Classe II, incluindo ortopedia funcional. A ortopedia funcional usa aparelhos para influenciar o crescimento do complexo craniofacial e normalizar a oclusão. Vários estudos experimentais em animais mostraram que fatores biomecânicos podem alterar o crescimento da cartilagem condilar e o comprimento final da mandíbula.
A empresa de tecnologia anunciou um novo smartphone com câmera aprimorada, maior tela e melhor desempenho. O dispositivo também possui um preço mais acessível em relação aos modelos anteriores para atrair mais consumidores. O lançamento ocorrerá no próximo mês e a empresa espera que o novo smartphone ajude a aumentar suas vendas e participação no mercado.
Este documento descreve parâmetros de controle em tomografia computadorizada, incluindo a colimação do feixe, os eixos de corte, o fator mAs, a alta tensão e o tempo de rotação do tubo. Explica como esses parâmetros afetam a qualidade da imagem e a dose de radiação do paciente. Também discute algoritmos de reconstrução usados para processar os dados coletados e gerar imagens.
Farmacologia e farmacovigilância relacionadas ao câncer da mamaTCC_FARMACIA_FEF
Este trabalho apresenta uma revisão sobre farmacologia e farmacovigilância relacionadas ao câncer de mama. Aborda os objetivos da pesquisa, métodos, revisão da literatura sobre câncer de mama incluindo tipos, fatores de risco, prevenção, diagnóstico e tratamento com foco na farmacoterapia e aspectos de farmacovigilância.
Este documento fornece um resumo da anatomia da cabeça óssea e das principais incidências radiográficas utilizadas para estudá-la, incluindo o crânio em AP, perfil, Towne e Waters. Ele descreve os ossos do crânio e da face, pontos anatômicos-chave, e detalha a posição correta do paciente e configurações técnicas para vários exames de raios-X da cabeça.
Nhận viết luận văn đại học, thạc sĩ trọn gói, chất lượng, LH ZALO=>0909232620
Tham khảo dịch vụ, bảng giá tại: https://vietbaitotnghiep.com/dich-vu-viet-thue-luan-van
Download luận văn đồ án tốt nghiệp ngành nuôi trồng thủy sản với đề tài: Ảnh hưởng của mật độ nuôi lên tăng trưởng, tỷ lệ sống và lợi nhuận trong nuôi tôm thẻ chân trắng thâm canh tại Thạnh Phú - Bến Tre
Este documento apresenta os resultados de uma pesquisa sobre a realidade de pacientes com câncer de próstata no Brasil. A maioria dos participantes tinha mais de 50 anos e não costumava fazer exames preventivos regularmente. Muitos relataram dificuldades para obter diagnóstico e tratamento em tempo hábil através do SUS, enfrentando também efeitos colaterais e problemas psicológicos decorrentes da doença e seu tratamento.
O documento discute a anatomia e desenvolvimento ósseo do cotovelo, com foco em lesões traumáticas. Ele descreve a anatomia do cotovelo, ângulo de condução ideal, e os principais centros de ossificação e suas idades de aparecimento em crianças.
O documento discute várias formas de correção da má-oclusão de Classe II, incluindo ortopedia funcional. A ortopedia funcional usa aparelhos para influenciar o crescimento do complexo craniofacial e normalizar a oclusão. Vários estudos experimentais em animais mostraram que fatores biomecânicos podem alterar o crescimento da cartilagem condilar e o comprimento final da mandíbula.
A empresa de tecnologia anunciou um novo smartphone com câmera aprimorada, maior tela e melhor desempenho. O dispositivo também possui um preço mais acessível em relação aos modelos anteriores para atrair mais consumidores. O lançamento ocorrerá no próximo mês e a empresa espera que o novo smartphone ajude a aumentar suas vendas e participação no mercado.
Este documento descreve parâmetros de controle em tomografia computadorizada, incluindo a colimação do feixe, os eixos de corte, o fator mAs, a alta tensão e o tempo de rotação do tubo. Explica como esses parâmetros afetam a qualidade da imagem e a dose de radiação do paciente. Também discute algoritmos de reconstrução usados para processar os dados coletados e gerar imagens.
Farmacologia e farmacovigilância relacionadas ao câncer da mamaTCC_FARMACIA_FEF
Este trabalho apresenta uma revisão sobre farmacologia e farmacovigilância relacionadas ao câncer de mama. Aborda os objetivos da pesquisa, métodos, revisão da literatura sobre câncer de mama incluindo tipos, fatores de risco, prevenção, diagnóstico e tratamento com foco na farmacoterapia e aspectos de farmacovigilância.
Este documento fornece um resumo da anatomia da cabeça óssea e das principais incidências radiográficas utilizadas para estudá-la, incluindo o crânio em AP, perfil, Towne e Waters. Ele descreve os ossos do crânio e da face, pontos anatômicos-chave, e detalha a posição correta do paciente e configurações técnicas para vários exames de raios-X da cabeça.
Nhận viết luận văn đại học, thạc sĩ trọn gói, chất lượng, LH ZALO=>0909232620
Tham khảo dịch vụ, bảng giá tại: https://vietbaitotnghiep.com/dich-vu-viet-thue-luan-van
Download luận văn đồ án tốt nghiệp ngành nuôi trồng thủy sản với đề tài: Ảnh hưởng của mật độ nuôi lên tăng trưởng, tỷ lệ sống và lợi nhuận trong nuôi tôm thẻ chân trắng thâm canh tại Thạnh Phú - Bến Tre
Este documento apresenta os resultados de uma pesquisa sobre a realidade de pacientes com câncer de próstata no Brasil. A maioria dos participantes tinha mais de 50 anos e não costumava fazer exames preventivos regularmente. Muitos relataram dificuldades para obter diagnóstico e tratamento em tempo hábil através do SUS, enfrentando também efeitos colaterais e problemas psicológicos decorrentes da doença e seu tratamento.
O documento discute a anatomia e desenvolvimento ósseo do cotovelo, com foco em lesões traumáticas. Ele descreve a anatomia do cotovelo, ângulo de condução ideal, e os principais centros de ossificação e suas idades de aparecimento em crianças.
O Tratamento Ortodôntico Antes Da ReabilitaçãO Oral OtimizandoJonas Ferreira
O documento discute o tratamento ortodôntico prévio à reabilitação oral para melhorar os resultados. A ortodontia pode organizar os dentes para facilitar implantes, próteses e restaurações de melhor qualidade. O tratamento ortodôntico em adultos requer planejamento diferente considerando problemas periodontais e financeiros. Mini-implantes podem ser usados para forças ortodônticas e melhorar movimentos como intrusão e retração.
O documento descreve as atividades e responsabilidades de um biomédico que atua na área de radiodiagnóstico e radioterapia, incluindo a operação de equipamentos médicos de imagem como raio-X, tomografia computadorizada e ressonância magnética, sob supervisão médica.
Este documento descreve os passos para a confecção de uma prótese total fixa sobre implantes usando o Protocolo Bränemark. Inicialmente apresenta um breve histórico dos implantes e sua classificação, seguido pelas etapas do planejamento protético-cirúrgico e da sequência para confecção da prótese, desde a moldagem até a entrega final. Por fim, discute as vantagens e desvantagens das próteses fixas em comparação às overdentures.
Palestra de Atualização Científica realizada no CRM-Ma promovida pela UFMA / LAGECAD (Setembro 2019).
Público-Alvo: Médicos, Residentes e Acadêmicos.
Objetivo: Princípios da Cirurgia Oncológica aplicada aos tumores do Aparelho Digestivo mais prevalentes.
Os Vídeos desta palestra estão disponíveis em nosso canal do You Tube.
O documento discute as vantagens da tomografia computadorizada de feixe cônico (cone-beam) em odontologia, incluindo menor dose de radiação, maior precisão dos exames, e capacidade de reproduzir imagens em 3D. Especialistas afirmam que a tomografia de feixe cônico preenche lacunas diagnósticas e possibilita avaliações detalhadas.
Inappropriate use of laboratory resources.pptxMoustafa Rezk
This document discusses inappropriate use of laboratory resources and provides strategies to overcome it. It finds that 60-70% of high-throughput laboratory tests may be inappropriate or of minor clinical relevance. Reasons for inappropriate testing include easy online ordering, defensive medicine, and lack of education on test value. Consequences include incorrect diagnoses, unnecessary follow-up tests, and increased costs. Strategies to address this include educational interventions, limiting tests through algorithms, and demand management like enforcing re-testing intervals and streamlining test panels. When correctly implemented with clinician approval, demand management can optimize testing to benefit patients, clinicians and hospitals.
O documento discute o papel da radiologia forense em três frases. Apresenta as qualificações da professora Renata Cristina em radiologia e suas especializações. Em seguida, descreve brevemente o que é a radiologia forense, suas principais técnicas como raio-x, tomografia computadorizada e ressonância magnética, e suas aplicações na identificação humana, estimativa de idade e em locais como institutos médico-legais, aeroportos e presídios.
Equipamentos médico hospitalares e o gerenciamento da manutençãopryloock
Este documento apresenta um guia sobre gerenciamento de manutenção de equipamentos médico-hospitalares e capacitação a distância. O guia aborda tópicos como implantação de programas de manutenção, elaboração de propostas de trabalho, gerenciamento de manutenção corretiva e preventiva. Inclui também capítulos sobre gerenciamento de serviços externos, aquisição de equipamentos médicos e fundamentos de segurança para unidades de saúde.
Protimplant: Portfolio de Manequins e Componentes ProtéticosN. David Harari
O documento descreve vários casos clínicos de pacientes edêntulos tratados com implantes e próteses fixas e removíveis. Ele também detalha os componentes utilizados nos tratamentos, incluindo análogos de implantes, pilares, sistemas de retenção e guias cirúrgicos. Finalmente, apresenta os grupos de manequins utilizados no curso prático de prótese sobre implante.
A próstata é uma glândula masculina que produz fluido seminal. O câncer de próstata é o tumor mais comum em homens acima de 50 anos, podendo afetar mais negros. Fatores de risco incluem idade, histórico familiar, dieta e sedentarismo. Exames como toque retal e dosagem de PSA diagnosticam, e biópsia confirma a doença. Tratamentos variam desde cirurgia e radioterapia para casos iniciais, até hormonioterapia para casos avançados.
This document provides an overview of drug rediscovery using the example of 6-thioguanine (6-TG) for inflammatory bowel disease (IBD). It discusses the current standard therapies for IBD, their limitations including side effects. 6-TG, which was previously only used for leukemia, shows promise as an alternative for patients who cannot tolerate standard thiopurines. Studies demonstrate the efficacy of 6-TG for IBD with response rates over 70% and less toxicity than other thiopurines. Low-dose 6-TG may avoid nodular regenerative hyperplasia seen at higher doses. Regulatory hurdles include the need for new clinical trials and difficulties with re-registration and distribution compared to redis
This document provides an overview of drug rediscovery using the example of 6-thioguanine (6-TG) for inflammatory bowel disease (IBD). It discusses the current standard therapies for IBD, their limitations including side effects. 6-TG, which was previously only used for leukemia, shows promise as an alternative for patients who cannot tolerate standard thiopurines. Studies demonstrate the efficacy of 6-TG for IBD with response rates over 70% and less toxicity than other thiopurines. Low-dose 6-TG may avoid nodular regenerative hyperplasia seen at higher doses. Regulatory hurdles include the need for new clinical trials and difficulties with re-registration and distribution compared to redis
Drugs used in special populations | Geriatric | Pediatric patients | Pregnant...Shaikh Abusufyan
Rectal diazepam would be an appropriate drug and route of administration for the casualty officer to terminate the convulsions in this case. Rectal administration provides a non-invasive alternative route when intravenous access cannot be obtained, and rectal diazepam is commonly used for the treatment of prolonged seizures in pediatric patients.
Rudolph Basson: Support or punish – reconsidered approaches to drug related h...SACAP
Harm Reduction acknowledges that drug use occurs and is potentially damaging, and attempts
to reduce and prevent these harms in ways, which are pragmatic and humanistic. Although the
harm reduction approach and specific harm reduction interventions (including needle and
syringe programmed and methadone programmed) have been implemented with resounding
success internationally (including in a number of African countries) for more than 20 years, the
South African approach to substance use and substance-related harms is still largely informed
by the doctrine and strategies of the "War on Drugs", and focuses almost exclusively on
prohibition and punishment. Because of the strong link between drug use and poverty, different
policy approaches to poverty and homelessness must also be considered. My talk will critically
examine these two approaches to drug use, poverty, and displacement (support or punish), as
they are being implemented in Cape Town. Opportunity for discussion will be provided.
The Critical Importance of Health Care Worker Leadership in the Tobacco Contr...Global Bridges
Presentation by Eduardo Bianco, M.D., Framework Convention Alliance, Uruguay, at the Global Bridges Preconference at the 15th World Conference on Tobacco OR Health in Singapore.
De las intervenciones breves a los farmacos. malaga 2015 Antoni Gual
Conferencia sobre los problemas derivados del alcoholismo y su tratamiento, impartida el 6 de marzo del 2015 en la reunión de la Red de Trastornos Adictivos, realizada el Hospital Universitario de Málaga
This document discusses the burden of kidney disease globally and in Nigeria. It notes that renal failure is a major public health problem worldwide, contributing to over 850,000 deaths annually. In Nigeria, chronic kidney disease accounts for 8-10% of hospital admissions, with an estimated 18,000 new cases per year. However, less than 2000 patients are able to receive dialysis treatment due to financial constraints. The document calls for government funding of dialysis treatment through programs like NHIS to increase access to life-saving care for kidney patients in Nigeria.
Closing the treatment gap in alcohol dependence thessalonika 2015Antoni Gual
Lecture on the treatment gap (underdiagnose & undertreatment) of alcohol use disorders. Presented at the 5th Conference of the Greek Psychiatric society in Thessalonika, march 21st, 2015.
1) The document discusses substance use disorders and related topics from Healthy People 2020, including goals to increase quality of life and eliminate health disparities, with a focus on mental health and substance abuse.
2) Key details are provided on substance abuse objectives from Healthy People 2020, federal agencies and national institutes involved in substance abuse treatment and research, common drugs of abuse, and diagnostic criteria for substance use disorders.
3) Statistics are presented on prevalence of substance use disorders in the US and high-risk groups like college students and military/veterans. Etiology, neurobiology, screening and assessment tools, physical exam findings, and stages of change are summarized.
Drug use in elderly and techniques to avoid polypharmacyDrSahilKumar
The document discusses drug use in the elderly and techniques to avoid polypharmacy. It notes that the elderly population is growing and takes a significant portion of medications while also being more sensitive to drug effects due to physiological changes. Polypharmacy, defined as taking more than 5 medications, is common in the elderly due to multiple comorbidities and providers. This can increase risks of adverse drug reactions, interactions, and non-adherence. The document recommends techniques for optimal prescribing in the elderly like reviewing all medications, simplifying regimens, and eliminating unnecessary drugs to help prevent polypharmacy and its risks.
Covid19 Immunoboosters : Role of Vitamin C Zinc and Vitamin DShivani Sachdev
Diet and nutrition invariably influence the immune system competence and determine the risk and severity of infections.
There are bi-directional relationships among diet, nutrition, infection, and immunity. The changes in one component have an impact on the others. Vitamin C may help shorten the duration and severity of colds caused by other viruses, but this is no guarantee that it will have the same effect on the coronavirus that causes COVID-19.
Nevertheless it is safe and inexpensive
The Upper Limit (UL) for supplemental vitamin C — the amount most people can consume daily without negative effects — is 2,000 mg .
Evidence That Vitamin D Supplementation Could Reduce Risk of Influenza and COVID-19 Infections and Deaths Nutrients 2020 Apr William B Grant. Lower viral replication rates
Reduce concentrations of pro-inflammatory cytokines that produce the inflammation that injures the lining of the lungs, leading to pneumonia. Increase concentrations of anti-inflammatory cytokines . Evidence supporting the role of vitamin D in reducing risk of COVID-19. Outbreak occurred in winter, a time when 25(OH)D3 concentrations are lowest
The number of cases in the Southern Hemisphere are low
Vitamin D deficiency has been found to contribute to acute respiratory distress syndrome
Case-fatality rates increase with age with chronic disease comorbidity, and also higher in dark skinned people and all of which are associated with lower 25(OH)D concentration
Vitamin-D and COVID-19: do deficient risk a poorer outcome? Fiona Mitchell Lancet 2020.
O Tratamento Ortodôntico Antes Da ReabilitaçãO Oral OtimizandoJonas Ferreira
O documento discute o tratamento ortodôntico prévio à reabilitação oral para melhorar os resultados. A ortodontia pode organizar os dentes para facilitar implantes, próteses e restaurações de melhor qualidade. O tratamento ortodôntico em adultos requer planejamento diferente considerando problemas periodontais e financeiros. Mini-implantes podem ser usados para forças ortodônticas e melhorar movimentos como intrusão e retração.
O documento descreve as atividades e responsabilidades de um biomédico que atua na área de radiodiagnóstico e radioterapia, incluindo a operação de equipamentos médicos de imagem como raio-X, tomografia computadorizada e ressonância magnética, sob supervisão médica.
Este documento descreve os passos para a confecção de uma prótese total fixa sobre implantes usando o Protocolo Bränemark. Inicialmente apresenta um breve histórico dos implantes e sua classificação, seguido pelas etapas do planejamento protético-cirúrgico e da sequência para confecção da prótese, desde a moldagem até a entrega final. Por fim, discute as vantagens e desvantagens das próteses fixas em comparação às overdentures.
Palestra de Atualização Científica realizada no CRM-Ma promovida pela UFMA / LAGECAD (Setembro 2019).
Público-Alvo: Médicos, Residentes e Acadêmicos.
Objetivo: Princípios da Cirurgia Oncológica aplicada aos tumores do Aparelho Digestivo mais prevalentes.
Os Vídeos desta palestra estão disponíveis em nosso canal do You Tube.
O documento discute as vantagens da tomografia computadorizada de feixe cônico (cone-beam) em odontologia, incluindo menor dose de radiação, maior precisão dos exames, e capacidade de reproduzir imagens em 3D. Especialistas afirmam que a tomografia de feixe cônico preenche lacunas diagnósticas e possibilita avaliações detalhadas.
Inappropriate use of laboratory resources.pptxMoustafa Rezk
This document discusses inappropriate use of laboratory resources and provides strategies to overcome it. It finds that 60-70% of high-throughput laboratory tests may be inappropriate or of minor clinical relevance. Reasons for inappropriate testing include easy online ordering, defensive medicine, and lack of education on test value. Consequences include incorrect diagnoses, unnecessary follow-up tests, and increased costs. Strategies to address this include educational interventions, limiting tests through algorithms, and demand management like enforcing re-testing intervals and streamlining test panels. When correctly implemented with clinician approval, demand management can optimize testing to benefit patients, clinicians and hospitals.
O documento discute o papel da radiologia forense em três frases. Apresenta as qualificações da professora Renata Cristina em radiologia e suas especializações. Em seguida, descreve brevemente o que é a radiologia forense, suas principais técnicas como raio-x, tomografia computadorizada e ressonância magnética, e suas aplicações na identificação humana, estimativa de idade e em locais como institutos médico-legais, aeroportos e presídios.
Equipamentos médico hospitalares e o gerenciamento da manutençãopryloock
Este documento apresenta um guia sobre gerenciamento de manutenção de equipamentos médico-hospitalares e capacitação a distância. O guia aborda tópicos como implantação de programas de manutenção, elaboração de propostas de trabalho, gerenciamento de manutenção corretiva e preventiva. Inclui também capítulos sobre gerenciamento de serviços externos, aquisição de equipamentos médicos e fundamentos de segurança para unidades de saúde.
Protimplant: Portfolio de Manequins e Componentes ProtéticosN. David Harari
O documento descreve vários casos clínicos de pacientes edêntulos tratados com implantes e próteses fixas e removíveis. Ele também detalha os componentes utilizados nos tratamentos, incluindo análogos de implantes, pilares, sistemas de retenção e guias cirúrgicos. Finalmente, apresenta os grupos de manequins utilizados no curso prático de prótese sobre implante.
A próstata é uma glândula masculina que produz fluido seminal. O câncer de próstata é o tumor mais comum em homens acima de 50 anos, podendo afetar mais negros. Fatores de risco incluem idade, histórico familiar, dieta e sedentarismo. Exames como toque retal e dosagem de PSA diagnosticam, e biópsia confirma a doença. Tratamentos variam desde cirurgia e radioterapia para casos iniciais, até hormonioterapia para casos avançados.
This document provides an overview of drug rediscovery using the example of 6-thioguanine (6-TG) for inflammatory bowel disease (IBD). It discusses the current standard therapies for IBD, their limitations including side effects. 6-TG, which was previously only used for leukemia, shows promise as an alternative for patients who cannot tolerate standard thiopurines. Studies demonstrate the efficacy of 6-TG for IBD with response rates over 70% and less toxicity than other thiopurines. Low-dose 6-TG may avoid nodular regenerative hyperplasia seen at higher doses. Regulatory hurdles include the need for new clinical trials and difficulties with re-registration and distribution compared to redis
This document provides an overview of drug rediscovery using the example of 6-thioguanine (6-TG) for inflammatory bowel disease (IBD). It discusses the current standard therapies for IBD, their limitations including side effects. 6-TG, which was previously only used for leukemia, shows promise as an alternative for patients who cannot tolerate standard thiopurines. Studies demonstrate the efficacy of 6-TG for IBD with response rates over 70% and less toxicity than other thiopurines. Low-dose 6-TG may avoid nodular regenerative hyperplasia seen at higher doses. Regulatory hurdles include the need for new clinical trials and difficulties with re-registration and distribution compared to redis
Drugs used in special populations | Geriatric | Pediatric patients | Pregnant...Shaikh Abusufyan
Rectal diazepam would be an appropriate drug and route of administration for the casualty officer to terminate the convulsions in this case. Rectal administration provides a non-invasive alternative route when intravenous access cannot be obtained, and rectal diazepam is commonly used for the treatment of prolonged seizures in pediatric patients.
Rudolph Basson: Support or punish – reconsidered approaches to drug related h...SACAP
Harm Reduction acknowledges that drug use occurs and is potentially damaging, and attempts
to reduce and prevent these harms in ways, which are pragmatic and humanistic. Although the
harm reduction approach and specific harm reduction interventions (including needle and
syringe programmed and methadone programmed) have been implemented with resounding
success internationally (including in a number of African countries) for more than 20 years, the
South African approach to substance use and substance-related harms is still largely informed
by the doctrine and strategies of the "War on Drugs", and focuses almost exclusively on
prohibition and punishment. Because of the strong link between drug use and poverty, different
policy approaches to poverty and homelessness must also be considered. My talk will critically
examine these two approaches to drug use, poverty, and displacement (support or punish), as
they are being implemented in Cape Town. Opportunity for discussion will be provided.
The Critical Importance of Health Care Worker Leadership in the Tobacco Contr...Global Bridges
Presentation by Eduardo Bianco, M.D., Framework Convention Alliance, Uruguay, at the Global Bridges Preconference at the 15th World Conference on Tobacco OR Health in Singapore.
De las intervenciones breves a los farmacos. malaga 2015 Antoni Gual
Conferencia sobre los problemas derivados del alcoholismo y su tratamiento, impartida el 6 de marzo del 2015 en la reunión de la Red de Trastornos Adictivos, realizada el Hospital Universitario de Málaga
This document discusses the burden of kidney disease globally and in Nigeria. It notes that renal failure is a major public health problem worldwide, contributing to over 850,000 deaths annually. In Nigeria, chronic kidney disease accounts for 8-10% of hospital admissions, with an estimated 18,000 new cases per year. However, less than 2000 patients are able to receive dialysis treatment due to financial constraints. The document calls for government funding of dialysis treatment through programs like NHIS to increase access to life-saving care for kidney patients in Nigeria.
Closing the treatment gap in alcohol dependence thessalonika 2015Antoni Gual
Lecture on the treatment gap (underdiagnose & undertreatment) of alcohol use disorders. Presented at the 5th Conference of the Greek Psychiatric society in Thessalonika, march 21st, 2015.
1) The document discusses substance use disorders and related topics from Healthy People 2020, including goals to increase quality of life and eliminate health disparities, with a focus on mental health and substance abuse.
2) Key details are provided on substance abuse objectives from Healthy People 2020, federal agencies and national institutes involved in substance abuse treatment and research, common drugs of abuse, and diagnostic criteria for substance use disorders.
3) Statistics are presented on prevalence of substance use disorders in the US and high-risk groups like college students and military/veterans. Etiology, neurobiology, screening and assessment tools, physical exam findings, and stages of change are summarized.
Drug use in elderly and techniques to avoid polypharmacyDrSahilKumar
The document discusses drug use in the elderly and techniques to avoid polypharmacy. It notes that the elderly population is growing and takes a significant portion of medications while also being more sensitive to drug effects due to physiological changes. Polypharmacy, defined as taking more than 5 medications, is common in the elderly due to multiple comorbidities and providers. This can increase risks of adverse drug reactions, interactions, and non-adherence. The document recommends techniques for optimal prescribing in the elderly like reviewing all medications, simplifying regimens, and eliminating unnecessary drugs to help prevent polypharmacy and its risks.
Covid19 Immunoboosters : Role of Vitamin C Zinc and Vitamin DShivani Sachdev
Diet and nutrition invariably influence the immune system competence and determine the risk and severity of infections.
There are bi-directional relationships among diet, nutrition, infection, and immunity. The changes in one component have an impact on the others. Vitamin C may help shorten the duration and severity of colds caused by other viruses, but this is no guarantee that it will have the same effect on the coronavirus that causes COVID-19.
Nevertheless it is safe and inexpensive
The Upper Limit (UL) for supplemental vitamin C — the amount most people can consume daily without negative effects — is 2,000 mg .
Evidence That Vitamin D Supplementation Could Reduce Risk of Influenza and COVID-19 Infections and Deaths Nutrients 2020 Apr William B Grant. Lower viral replication rates
Reduce concentrations of pro-inflammatory cytokines that produce the inflammation that injures the lining of the lungs, leading to pneumonia. Increase concentrations of anti-inflammatory cytokines . Evidence supporting the role of vitamin D in reducing risk of COVID-19. Outbreak occurred in winter, a time when 25(OH)D3 concentrations are lowest
The number of cases in the Southern Hemisphere are low
Vitamin D deficiency has been found to contribute to acute respiratory distress syndrome
Case-fatality rates increase with age with chronic disease comorbidity, and also higher in dark skinned people and all of which are associated with lower 25(OH)D concentration
Vitamin-D and COVID-19: do deficient risk a poorer outcome? Fiona Mitchell Lancet 2020.
New Policies Needed to Reduce the Global Burden of Ageing Related PathologiesIndia Future Society
This document discusses the need for new policies to address the global burden of age-related diseases. It notes that longevity research is highly specialized across different countries. It also shows that non-communicable diseases account for a large share of deaths globally, especially in higher income countries, and this share is projected to increase further by 2030. The document advocates for three main policy changes: 1) increasing funding for research on the biology of aging, 2) providing beneficial regulation for biotechnologies aimed at preventing aging, and 3) reforming clinical trial processes to make them less costly and better support the development of preventive medicines and anti-aging interventions.
This document discusses the role of micronutrients in improving immune function and fighting HIV/AIDS. It provides several key points of evidence:
1) Studies have shown that high doses of vitamin C can block the replication of HIV by more than 99%.
2) Vitamins B3, B5, B6, B12, C, folic acid, iron and others are essential for blood cell formation and optimum immune function.
3) Deficiencies in these micronutrients compromise the formation and function of white and red blood cells. Supplementation has been used successfully to treat deficiencies and diseases.
Nc ds in adolescents sampi, sept 3, 2014Ted Herbosa
This document discusses non-communicable diseases (NCDs) in adolescents in the Philippines. It provides statistics on the burden and prevalence of NCDs both globally and domestically. NCDs such as cardiovascular diseases, cancer, diabetes and chronic lung disease cause over 36 million deaths annually, or 63% of all global deaths. In the Philippines specifically, 10 Filipinos die every hour from smoking or secondhand smoke. Risk factors like hypertension, hyperglycemia, overweight/obesity and smoking are on the rise. The Department of Health has initiated several policies, programs and financing measures to address lifestyle-related NCDs through legislation, health promotion, and expanding access to services.
DIRI with commercial available agents ,,,.pdfMOHITROCK1
review articles 7th semester b pharm final year
topic: Drug Induced Renal Injury (DIRI): Alarming indication towards the
catastrophic behavior of drugs
Materials and Methods of DIRI
Renal manifestations of recrea
Nephrotoxicity of Ciprofloxaci
Herbal Nephropathy (Cranberry)
B PHARM
Study of Medicinal Plants in Management of Naphrotoxicityijtsrd
Nephrotoxicity is one of the most common kidney problems and occurs when body is exposed to a drug or toxin. A number of therapeutic agents can adversely affect the kidney resulting in acute renal failure, chronic interstitial nephritis and nephritic syndrome. Agents Which Causes Nephrotoxicity Drugs, diagnostic agents and chemical are well known to be nephrotoxic. To avoid the side effect of synthetic drug there is need to develop a safe and effective Polyherbal In view of foregoing consideration. Our present study aims at the scientific validation of nephroprotective and antioxidant properties of selected plant and formulation of suitable novel dosage so that new herbal drug will come in the market. Ms. Jyoti Singh | Dr. Bishnu Kumar | Dr. Shailesh Gupta "Study of Medicinal Plants in Management of Naphrotoxicity" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-6 | Issue-7 , December 2022, URL: https://www.ijtsrd.com/papers/ijtsrd52459.pdf Paper URL: https://www.ijtsrd.com/pharmacy/pharmacognosy-/52459/study-of-medicinal-plants-in-management-of-naphrotoxicity/ms-jyoti-singh
The document discusses polypharmacy and its risks in elderly patients. It notes that 12% of the population is aged 65+ but this group accounts for 30% of prescription drug use and 50% of over-the-counter drug use. Polypharmacy increases the risk of adverse drug reactions in elderly patients due to changes in pharmacokinetics and pharmacodynamics with aging as well as an increased likelihood of drug-drug interactions. Prudent prescribing for older adults includes considering potential drug-disease interactions, assessing compliance, and considering non-pharmacological options before prescribing additional medications.
The document discusses several key aspects of pharmacology in the elderly population. It describes how the aging process can impact absorption, distribution, metabolism and excretion of drugs. It also addresses increased risk of polypharmacy, adverse drug reactions, and use of potentially inappropriate medications in elderly patients. Additionally, it mentions factors like the placebo and nocebo effect that can influence drug responses in older adults. The conclusion emphasizes the importance of considering the physiological changes of aging when determining safe and effective pharmacotherapy for elderly individuals.
Similar to Presentación de MRF en geriatría (Dr. Bianchi) (20)
El documento describe la composición de CELLFOOD, un suplemento nutricional. Contiene una amplia variedad de minerales, aminoácidos, enzimas y electrolitos que proporcionan nutrientes esenciales para el cuerpo. Al tomar CELLFOOD, algunas personas pueden experimentar una "crisis de curación" en la que el cuerpo elimina toxinas acumuladas, lo que puede causar síntomas temporales de desintoxicación. Esto es un signo positivo de que el cuerpo se está limpiando a profundidad. Siguiendo las
I. Un estudio prospectivo evaluó el efecto de Rowatinex® en 50 pacientes tratados con litotripsia para cálculos renales o ureterales.
II. A los 14 días, el 60% de pacientes estaban libres de cálculos y el 82% a los 28 días.
III. Los resultados para el alivio de dolor también fueron excelentes, con un 82% libres de dolor a los 14 días y un 94% a los 28 días.
La dispepsia o indigestión se define como un síntoma que incluye náuseas, ardor de estómago y dolor abdominal superior. Rowachol contiene seis terpenos purificados que mejoran la bilis, son coleréticos, antiespasmódicos, estimulan la secreción pancreática y tienen efectos carminativos, lo que alivia los síntomas de la dispepsia. Varios estudios con animales y humanos han demostrado que Rowachol mejora la función del sistema digestivo y la composición de la bilis.
This document is a medication guide for non-steroidal anti-inflammatory drugs (NSAIDs) that outlines important safety information. It states that NSAIDs can increase the risk of heart attack, stroke, ulcers and bleeding in the stomach and intestines. It lists common side effects like stomach pain and serious side effects like kidney problems. The guide provides information on who should not take NSAIDs and cautions to stop use and seek medical help if concerning symptoms arise. It also lists examples of prescription NSAID medicines.
Este documento describe un estudio clínico sobre el tratamiento de la celulitis mediante mesoterapia homeopática y fitoterapia. El estudio incluyó 1,564 pacientes tratados entre 1991 y 1994 con una mezcla homeopática llamada Lipodistrofin inyectada mediante mesoterapia, complementada con tratamientos dietéticos, de ejercicio y aplicaciones tópicas. Los resultados mostraron mejoras en la pérdida de peso, disminución del diámetro de la cintura y síntomas relacionados con la celulitis, sin efectos
This study evaluated the effectiveness of Osteobios and Guna-Fem supplements for treating early postmenopausal osteoporosis compared to calcium and vitamin D supplements. 70 postmenopausal women with osteoporosis were divided into two groups. The group treated with Osteobios and Guna-Fem showed greater reductions in pain levels, improvements in quality of life, and decreases in bone resorption markers compared to the calcium/vitamin D group. The results suggest Osteobios and Guna-Fem may be effective treatments for reducing symptoms of early postmenopausal osteoporosis.
This document discusses using cytokines and homeopathic dilutions therapeutically. It argues that cytokines, which are protein molecules that regulate the immune system, can be used in homeopathic form to help defend the body against illness. The document states that homeopathy uses extremely diluted stimuli that are able to precisely target ultrafine body structures. It asserts that this approach can help restore balance to the complex fractal dynamics of various biological systems interacting in the body. Overall, the document proposes that cytokines can be applied homeopathically to provide a balanced, non-toxic stimulation that supports the body's natural healing responses.
The document summarizes a study on the use of Osteobios to treat calcium metabolism disorders in patients with chronic kidney disease stages II-III. 20 patients received Osteobios drops daily for a month in addition to other treatments, while a control group of 20 similar patients received no such treatment. Testing showed improvements in calcium, phosphorus, parathyroid hormone, and pain levels in the treatment group compared to baseline and the control group. The study concluded that Osteobios safely improves calcium metabolism in patients with chronic kidney disease without the need for additional medications.
Physiological Regulating Medicine (PRM) is the latest integration between Conventional Medicine and Homeopathic Medicine. PRM integrates classic Homeopathy with a new therapeutic concept - the restoration of physiological conditions through molecules such as hormones, neuropeptides, interleukins and growth factors in homeopathic dilutions corresponding to physiological concentrations. The method includes current knowledge on Homeopathy, Homotoxicology, the Psycho-Neuro-Endocrine-Immune axis, and nutrition. PRM offers injectable formulations for the control of nociceptive, neuropathic and mixed pain that can be injected into acupuncture points with excellent therapeutic results and no side effects.
Este documento presenta los resultados de un estudio multicéntrico sobre el uso de la mesoterapia homeopática con Condrotrofín R para tratar la patología articular. El estudio evaluó 200 pacientes durante 5 semanas y encontró una mejoría significativa de los síntomas en el 40% de los pacientes después de la primera semana de tratamiento. El tratamiento con Condrotrofín R redujo la necesidad de medicamentos convencionales y fue bien aceptado por los pacientes.
1. The extracellular matrix (ECM) represents the basic system of living organisms, where nourishment, control, and management of cells takes place through mutual information exchange.
2. The ECM is composed of proteoglycans and glycosaminoglycans which help maintain homeostasis. It also contains collagen, elastin, and other glycoproteins.
3. Over a lifetime, catabolites can accumulate in the ECM, making energy exchange between cells more difficult and contributing to the aging process. Physiological Regulating Medicine aims to cleanse and restore the ECM, such as through the product GUNA-MATRIX.
This study aimed to determine the safety and efficacy of three popular mesotherapy cocktails in treating localized fat deposits in Filipino women. Sixty subjects received injections of one of three cocktails - phosphatidylcholine and organic silicium (PC-OS), phaphatidylcholine, tiratricol and L-carnitine (PC+L), or the homeopathic formula Omeoformula 1. Measurements and blood tests showed PC-OS and Omeoformula 1 were comparable in reducing arm circumference and had fewer adverse effects than PC+L. Overall, mesotherapy was deemed safe and effective for reducing localized fat deposits with some benefit to HDL and LDL cholesterol levels.
Este estudio experimental evaluó los efectos de un preparado homeopático llamado Musclebig en parámetros antropométricos y dinamométricos de 32 culturistas masculinos. Los participantes fueron asignados aleatoriamente a un grupo tratado con inyecciones de Musclebig o a un grupo control. Tras 12 semanas, el grupo tratado mostró aumentos estadísticamente significativos en su índice de masa corporal, masa magra y fuerza de resistencia, así como una disminución en la grasa corporal, en comparación con el
The document describes a clinical study on 681 patients that evaluated the efficacy of the homeopathic remedy MADE® in treating wrinkles and skin slackening. The study found MADE® to be an effective alternative to conventional pharmacological treatments, showing good results in preventing and treating wrinkles and skin slackening, especially in patients aged 30-40 and 40-50.
1. The study investigated the effectiveness of antihomotoxic preparations Traumeel S and Osteobios in combination treatment of degenerative spinal diseases. Patients receiving these preparations in addition to traditional therapy saw greater improvements in pain, mobility, and bone healing markers than the control group receiving only traditional therapy.
2. Specifically, those receiving Traumeel S injections and ointment experienced greater reductions in pain levels and muscle spasms after 4 days compared to the control group. They also had faster wound healing after surgery.
3. The group also receiving Osteobios showed higher blood alkaline phosphatase levels upon discharge, indicating increased bone formation compared to the control group. This supported Osteobios' role
This document discusses inflammation and cytokines. It notes that cytokines are proteins secreted by immune cells in response to antigens that induce inflammation. Cytokines influence each other in cascades and have pleiotropic, redundant, synergistic and antagonistic effects. Their secretion is brief and self-limiting, requiring multiple cytokines in relay to achieve a targeted biological response. Physiological regulating medicine uses homeopathic cytokines and other remedies to reset and coordinate the immune system.
The document discusses the transition from homeopathy to physiological regulating medicine (PRM). While homeopathy is based on the principle of treating "like with like" using highly diluted substances, PRM was developed by an Italian research group inspired by homeopathy but aiming to have a more scientifically valid treatment approach based on the latest immunology and neuroendocrinology discoveries. Key aspects of homeopathy discussed include the principle of similarity in symptom matching, and the use of potentized dilutions, which some research has found can induce physical changes in water and potentially have physiological effects.
The document discusses the transition from homeopathy to physiological regulating medicine (PRM). While homeopathy is based on the principle of treating "like with like" using highly diluted substances, PRM was developed by an Italian research group inspired by homeopathy but aiming to have a more scientifically valid treatment approach based on the latest immunology and neuroendocrinology discoveries. Key aspects of homeopathy discussed include the principle of similarity in symptom matching, and the use of potentized dilutions, which some research has found can induce physical changes in water and potentially have physiological effects.
These lecture slides, by Dr Sidra Arshad, offer a quick overview of the physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar lead (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
6. Describe the flow of current around the heart during the cardiac cycle
7. Discuss the placement and polarity of the leads of electrocardiograph
8. Describe the normal electrocardiograms recorded from the limb leads and explain the physiological basis of the different records that are obtained
9. Define mean electrical vector (axis) of the heart and give the normal range
10. Define the mean QRS vector
11. Describe the axes of leads (hexagonal reference system)
12. Comprehend the vectorial analysis of the normal ECG
13. Determine the mean electrical axis of the ventricular QRS and appreciate the mean axis deviation
14. Explain the concepts of current of injury, J point, and their significance
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. Chapter 3, Cardiology Explained, https://www.ncbi.nlm.nih.gov/books/NBK2214/
7. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Basavarajeeyam is a Sreshta Sangraha grantha (Compiled book ), written by Neelkanta kotturu Basavaraja Virachita. It contains 25 Prakaranas, First 24 Chapters related to Rogas& 25th to Rasadravyas.
Here is the updated list of Top Best Ayurvedic medicine for Gas and Indigestion and those are Gas-O-Go Syp for Dyspepsia | Lavizyme Syrup for Acidity | Yumzyme Hepatoprotective Capsules etc
Cell Therapy Expansion and Challenges in Autoimmune DiseaseHealth Advances
There is increasing confidence that cell therapies will soon play a role in the treatment of autoimmune disorders, but the extent of this impact remains to be seen. Early readouts on autologous CAR-Ts in lupus are encouraging, but manufacturing and cost limitations are likely to restrict access to highly refractory patients. Allogeneic CAR-Ts have the potential to broaden access to earlier lines of treatment due to their inherent cost benefits, however they will need to demonstrate comparable or improved efficacy to established modalities.
In addition to infrastructure and capacity constraints, CAR-Ts face a very different risk-benefit dynamic in autoimmune compared to oncology, highlighting the need for tolerable therapies with low adverse event risk. CAR-NK and Treg-based therapies are also being developed in certain autoimmune disorders and may demonstrate favorable safety profiles. Several novel non-cell therapies such as bispecific antibodies, nanobodies, and RNAi drugs, may also offer future alternative competitive solutions with variable value propositions.
Widespread adoption of cell therapies will not only require strong efficacy and safety data, but also adapted pricing and access strategies. At oncology-based price points, CAR-Ts are unlikely to achieve broad market access in autoimmune disorders, with eligible patient populations that are potentially orders of magnitude greater than the number of currently addressable cancer patients. Developers have made strides towards reducing cell therapy COGS while improving manufacturing efficiency, but payors will inevitably restrict access until more sustainable pricing is achieved.
Despite these headwinds, industry leaders and investors remain confident that cell therapies are poised to address significant unmet need in patients suffering from autoimmune disorders. However, the extent of this impact on the treatment landscape remains to be seen, as the industry rapidly approaches an inflection point.
TEST BANK For An Introduction to Brain and Behavior, 7th Edition by Bryan Kol...rightmanforbloodline
TEST BANK For An Introduction to Brain and Behavior, 7th Edition by Bryan Kolb, Ian Q. Whishaw, Verified Chapters 1 - 16, Complete Newest Versio
TEST BANK For An Introduction to Brain and Behavior, 7th Edition by Bryan Kolb, Ian Q. Whishaw, Verified Chapters 1 - 16, Complete Newest Version
TEST BANK For An Introduction to Brain and Behavior, 7th Edition by Bryan Kolb, Ian Q. Whishaw, Verified Chapters 1 - 16, Complete Newest Version
Rasamanikya is a excellent preparation in the field of Rasashastra, it is used in various Kushtha Roga, Shwasa, Vicharchika, Bhagandara, Vatarakta, and Phiranga Roga. In this article Preparation& Comparative analytical profile for both Formulationon i.e Rasamanikya prepared by Kushmanda swarasa & Churnodhaka Shodita Haratala. The study aims to provide insights into the comparative efficacy and analytical aspects of these formulations for enhanced therapeutic outcomes.
TEST BANK For Basic and Clinical Pharmacology, 14th Edition by Bertram G. Kat...rightmanforbloodline
TEST BANK For Basic and Clinical Pharmacology, 14th Edition by Bertram G. Katzung, Verified Chapters 1 - 66, Complete Newest Version.
TEST BANK For Basic and Clinical Pharmacology, 14th Edition by Bertram G. Katzung, Verified Chapters 1 - 66, Complete Newest Version.
TEST BANK For Basic and Clinical Pharmacology, 14th Edition by Bertram G. Katzung, Verified Chapters 1 - 66, Complete Newest Version.
TEST BANK For Basic and Clinical Pharmacology, 14th Edition by Bertram G. Katzung, Verified Chapters 1 - 66, Complete Newest Version.
1. 11
Prof. Ivo Bianchi M.D.USA - CANADA
June 2008
PRM : The Aging
Process and Geriatrics
2. 22
Disclaimer
n This lecture is based on Prof. Ivo Bianchi’s
own clinical experience and his studies in
PRM.
n This lecture is not a prescription and we do
not accept medical or legal responsibility
for misuse of information.
Some of the remedies and techniques
might not be available in your Country and
you must adapt the content to the law of
your Country and to the jurisdiction of
your licensing board.
113. 113113
Theories on Aging
n Telomerase
n Membrane
n Mithocondrial Decline
n Genetic
n Free Radicals
n Cross Linking
n Hayflick
n Neurological
n Neuroendocrine
n Immunologic
114. 114114
PRM’s Position
n Each Theory is Right for a Specific
Patient
n Aging Factor are Different for Different
Individuals
n Therapy must take into account the
Specific deteriorating Factor to be cured
189. 189189
Why do we need
GUNA Matrix ?
n PRM gives a particular importance
to Connective Tissue functions and
Matrix role in Pathology and
expecially in Aging process.
n Matrix is the true “System of
basal Regulation”: all the changes
in our external and internal
environment influence, through
the fundamental substance,
cellular functions
190. 190190
Physiological Functions of
Connective Tissue - Matrix
n Structural framework for the body (bone,
cartilage)
n Transport nutrients and wastes (blood)
n Protection for vital organs (bone, cartilage,
adipose)
n Support and interconnection (tendons,
ligaments, capsules)
n Communication medium of Cells
n Energy storage and production of important cells
of blood and lymphatic tissues (adipose tissue,
bone marrow)
n Body defense and repair (blood, lymph, dense
c.t.)
191. 191191
Basic Role of Matrix
The communication between cells and external
environment takes place through the
connectival matrix
Huge is the quantity of information that can be
stored in the matrix and transmitted to the cells
as instructions for their physiological activity.
The neurovegetative endings branch out in the
matrix through neural and endocrine
substances, and cytokines, the psycho-neuro-
endocrine-immunologic information
coordinates and controls cells’ activity by
means of the binding with the cell receptors.
192. 192192
Possible Pathogenetic Role of
Matrix in Diseases
n A stressors accumulation
in this place represents the
potential trigger for the
beginning and the
progression of a
pathological process.
195. 195195
NAD
n NAD is a foundamental factor of metabolism of
Pyruvic acidum and Cell’s energy production
n NAD is the fundamental coenzyme for all the
oxidative energy-yielding pathways
196. 196196
C
COO-
COO-
Natrium oxalaceticum
n Oxalacetic acid is in connection with Ca2+ transport in
mitochondria.
n control of Ca2+ levels plays a significant role in enzymatic
regulation and energy production. Pathological conditions that
result in increased tissue Ca2+ concentrations, such as ischemia,
oxidative stress, and excito- and neurotoxicity, involve
impairment of the continued ability of Ca2+-regulating
organelles, such as sarcolemma, mitochondria, and
sarcoplasmic reticulum, to provide long-term control of cellular
Ca2+ levels.
n The subsequent increase in cytoplasmic Ca2+ is widely
considered to be a critical initiating event in the development of
damage in cells destined to die.
n excessive free cytosolic Ca2+ may lead to uncoupling of
mitochondrial oxidative phosphorylation with consequently
decreased ATP synthesis. The resulting inactivity of ATP-
dependent pumps would lead to membrane depolarizaiton and
further cellular Ca2+ influx in a regenerative and self-
potentiating mechanism.
n In this context, removal of Ca2+ to the extracellular space
and/or uptake into organelles, including mitochondria, work to
restore the normal cytoplasmic Ca2+ concentration, as occurs
during the early stages of recirculation after short-term cerebral
ischemia.
CH
2
O
197. 197197
TRICHYNOIL
n Very active stimulating quinon
n Activates energy production
systems at mythocondrial level
n Useful in viral conditions and in
low energy conditions
n Alone may be too strong and a
possible source of free radicals
n In low quantities and in sinergic
association it is an important
factor in cell and tissue reactivity
198. 198198
Hystidine
n Several lines of evidence indicate that
the histaminergic (HA) system is
important for wakefulness and
behavioral state regulation.
199. 199199
Hormones and Aging
Incidenza di MorteGH
ESTROGENI DEL CICLO
ESTROGENI BASALI
CORTISOLO
MELATONINA
DHEA
ANNI DI VITA
100=VALOREMASSIMO
MELATONIN
GH
DHEA
BASAL ESTROGENS
CORTISOL
Death incidence
CYCLE ESTROGENS
YEARS OF AGE
100=highestvalue
200. 200200
Prolactin
n Prolactin has
ä Regulatory function over Appetite
and Sexual behaviour acting on
dopaminergic neurons in CNS
ä Modulatory role in several aspects
of immune function
n Dopamine serves as the
major prolactin-inhibiting
factor Agents and drugs that
interfere with dopamine
secretion or receptor binding
lead to enhanced secretion
of Prolactin.
201. 201201
Melatonin and Prolactin
n Melatonin reduces DHEA at
night, this reduction is achieved
by inhibitory actions of
Melatonin on production of
Prolactin.
n Prolactin secretion may be
shown to specifically stimulate
production of DHEA.
n When Melatonin release is
high, PRL is reduced, which
reduces DHEA production.
205. 205205
IL - 6
n Previously associated with the acute phase response to
trauma and infection, when the liver produces
increased amounts of "acute phase proteins" which
help to deal with bacterial infections, including C-
reactive protein, mannan-binding lectin, fibrinogen,
haptoglobin, ferritin, ceruloplasmin, alpha1-antitrypsin
and alpha1-acid glycoprotein.
n Recent work has shown that IL-6 is produced by
exercising muscle, when it appears to have anti-
inflammatory actions. It may be that IL-6 is involved in
the adaptive response to pro-inflammatory signals,
and that it may antagonise TNF-α rather than acting in
a similar way. This could explain the generally
beneficial effects of increased exercise on chronic
inflammatory conditions.
207. 207207
DHEA and IL-6
n Data indicate a functional link between
DHEA and IL-6.
n The increase in IL-6 production during
the process of aging might be due to
diminished DHEA
208. 208208
Lactic acid
n A low quantity of Lactic
acid is stimulating the
metabolism of the
substance and helps
regulating the Matrix’s
pH , not allowing
accumulation of toxins,
gelification of medium
…
213. 213213
PRM’S GENERAL
REMEDIES
n GUNA Lympho
n GUNA Matrix
n GUNA Cell
n GUNA Fem
n GUNA Male
n MADE
n GUNA Mood
n GUNA Sport
n GUNA Trauma
n GUNA Arthro
n GUNA Flam
n GUNA Tonsils
n GUNA React
n GUNA Flu
n GUNA Virus
n EUBIOFLOR
n CITOMIX
n ANTI AGE Stress
n ANTI AGE Skin
n ANTI AGE Face
n ANTI AGE Vein
n GUNA Dizzy
214. 214214
PRM’S SPECIFIC REMEDIES
n Osteobios
n Micox
n GUNA TF Herpes
n GUNA TF Candida
n GUNA TF Papilloma
n GUNA Sinus Nose spray
n GUNA Rhino Nose spray
n GUNA Throat
n GUNA Cough
n GUNA Allergy Prev
n GUNA Allergy Treat
n GUNA PMS
n GUNA Bowel
n GUNA Haemorroids
n GUNA Digest
n GUNA Stomach
n GUNA Liver
n GUNA Kidney
n GUNA Diur
n GUNA Sleep
n GUNA Dermo
n GUNA Addict 1
n GUNA Addict 2
234. 234234
Osteoporosis
n Osteoporosis is a loss of bone density among
aging adults that can cause painful fractures,
disability and deformity.
n Osteoporosis affects both sexes but is more
frequent among women. It is estimated that
about one out of four women and one out of
eight men over the age of 50 in Canada have
osteoporosis.
n Bones are constantly being renewed naturally.
But with age, this process becomes less efficient,
and bone mineral density is lost.
237. 237237
BenignProstate Hypertrophia
n Testosterone is reduced by the enzyme 5-a-reductase to DHT
which is then thought to be the real culprit. The argument
between the use of Saw Palmetto, Pygeum and Pumpkin
seeds vs Proscar are both directed at blocking this enzyme.
Strangely, DHT is most important for sexual vigor, so
blocking this step may have some unintended consequences!
n On the other hand, Testosterone is also converted into
estradiol by aromatase (producing the aromatic ring). This
occurs increasingly with age in the liver but most importantly
... in the fat stores.
n Now you see the connection. As we age, and frequently gain
increasing fat stores, we are feeding the aromatase
connection, increasing our estradiol levels and if this theory
holds, increasing the promotion of prostate disease.
n It also raises the interesting possibility, that we find absent in
all other discussions (although certainly not proven), that
blocking the 5-a-reductase step may actually exacerbate the
problem by further increasing estrogen levels which is the
initiator of the problem to begin with.
240. 240240
Constipation of the Elderly
n Approximately 20 million people in
the western world suffer from chronic
constipation. Sufferers are from all
walks of life, but constipation is
particularly prevalent amongst the
aged, paraplegics of the lower limbs,
and the chronically ill.
Free-Lax is the world's first natural,
non-drug, non-invasive, non-habit-
forming constipation relief device.
244. 244244
SIDE EFFECTS OF CHEMOTHERAPY
IN THE ELDERLY
n Chemotherapy drugs are made to kill fast-
growing cells, but because these drugs travel
throughout the entire body, they can affect
normal, healthy cells, too. Damage to healthy
tissue causes side effects.
n It's uncertain whether chemotherapy may be less
well tolerated by elderly patients. Some issues in
aging patients, such as multiple medications and
other medical problems, may complicate cancer
treatment. A study showed, however, that
elderly cancer patients who are not suffering
from medical complications can receive the same
benefits and levels of toxicity as younger
patients.