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Under Observation:
Specialist Dr. Ghulam Reza Riaz
Submitted By:
Dr. Somaya Banaei
General surgery resident
Afghanistan-Herat Regional Hospital
Juan. 2021
Perioperative Care
Preoperative phase – begins when the decision to have surgery is made and
ends when the client is transferred to the OR table.
Intraoperative phase – begins when the client is transferred to the OR table and
ends when the client is admitted to the PACU.
Postoperative phase - begins with the admission of the client to the
PACU and ends when the healing is complete.
By: Dr. Somaya Banaei
Perioperative Care
Preoperative phase – begins when the decision to have surgery is made and
ends when the client is transferred to the OR table.
Intraoperative phase – begins when the client is transferred to the OR table and
ends when the client is admitted to the PACU.
Postoperative phase - begins with the admission of the client to the
PACU and ends when the healing is complete.
By: Dr. Somaya Banaei
DIAGNOSIS- PREOPERATIVE EVALUATION - PREPARATION
Perioperative Care
Preoperative phase – begins when the decision to have surgery is made and
ends when the client is transferred to the OR table.
Intraoperative phase – begins when the client is transferred to the OR table and
ends when the client is admitted to the PACU.
Postoperative phase - begins with the admission of the client to the
PACU and ends when the healing is complete.
By: Dr. Somaya Banaei
ANESTHESIA - OPERATION
Perioperative Care
Preoperative phase – begins when the decision to have surgery is made and
ends when the client is transferred to the OR table.
Intraoperative phase – begins when the client is transferred to the OR table and
ends when the client is admitted to the PACU.
Postoperative phase - begins with the admission of the client to the
PACU and ends when the healing is complete.
By: Dr. Somaya Banaei
POST ANESTHESIA CARE – ICU – INTERMEDIATE CARE- CONVALESCENCE PERIOD
DEFINITION
 The preoperative period runs from the time the patient is admitted
to the hospital or surgicenter to the time that the surgery begins.
 Preoperative begins with the decision to perform surgery and
continues until the client has reached the operating area.
By: Dr. Somaya Banaei
INTRODUCTION
The preoperative management of any patient is part of a continuum
of care that extends from:
THE SURGEON’S INITIAL CONSULTATION
through
THE PATIENT’S FULL RECOVERY.
It depends on:
Cause
&
severity of recent
problem
By: Dr. Somaya Banaei
The surgeon is responsible for
Balancing The Hazards of the natural history
of the condition if left untreated versus the risks of an operation.
 Not to screen broadly for undiagnosed disease
 Identify and quantify any comorbidity that may affect the operative outcome
The aim of preoperative evaluation
By: Dr. Somaya Banaei
Steps to preoperative Evaluation
 History and physical examination.
 Surgical Risk Factors
 Preoperative Testing
 Perioperative Management of medications
By: Dr. Somaya Banaei
Principles of History taking
 Listen: What is the problem? (Open questions)
 Clarify: What does the patient expect? (Closed questions)
 Narrow: Differential diagnosis (Focused questions)
 Fitness: Comorbidities (Fixed questions)
By: Dr. Somaya Banaei
SOCRATES
Site
Onset
Character
Radiation
Association
Time course
Exacerbating/relieving factors
Severity
By: Dr. Somaya Banaei
OPQRST
Onset
Precipitant
Quality
Radiation
Stop
Temporal
By: Dr. Somaya Banaei
Cardiovascular
IHD, HTN, heartfailure, dysrhythmias,PVD,
DVT,anemia
Respiratory
COPD, asthma,fibrotic lung, conditions,
respiratory infection, malignancy
Gastrointestinal
PUD, bowel habits, malignancy, liver
disease
GenitoUrinary tract
UTI, renal dysfunction
Past medical History
Neurological
Epilepsy, CVA, psychiatric disorder, cognitive
function
Endocrine / metabolic
Diabetes, thyroid dysfunction,
phaeochromocytoma
Locomotor system
Osteoarthritis, inflammatory arthropathy
Infectious
Tuberculosis, hepatitis, HIV
Past medical History
Physical examination
 Nervous system
 Peripheral pulses
 Ischemic history(claudication, diabetes)
 Rectal and Pelvic exam
 Pop smear (>30 years)
By: Dr. Somaya Banaei
Laboratory Exams
By: Dr. Somaya Banaei
 Check CBC
 Serum electrolytes
 Chest x-ray
 ECG
 Antibiogram in open wounds
( >40 years old)
( >50 years old)
Preoperative evaluation and general condition
 Peripheral perfusion
 Neck vein in rest
 Orthostatic changes in BP & PR
 Hemoglobin for satisfied
perfusion
 Function of Liver / kidney
 Mental status
 History of bleeding
 Drug history
 Allergy or drugs reaction
By: Dr. Somaya Banaei
Blood transfusion
preparation
Autologous transfusion
Blood store
Hemodilution
Phlebotomy
By: Dr. Somaya Banaei
Operative mortality
 Is expressed in terms of deaths occurring during surgery
 And up to 28 – 30 days after surgery
 70% of all elective procedure have a mortality risk <1%
 The high risk group has a mortality risk in EXCESS OF 5%
 When the risk exceeds 20% patients are said to be extremely high risk
 High risk patients - 12.5% of all surgical procedures
 > 80% of deaths
By: Dr. Somaya Banaei
0
0.5
1
1.5
2
2.5
3
3.5
4
4.5
5
Overal Standard High Risk
Population size (milione) Postoperative mortality (%)
Size and mortality rates for different population of
surgical patients
By: Dr. Somaya Banaei
Causes
After surgery
 Tissue destruction
 Blood loss
 Fluid shifts
 Change in temperature
 Pain and anxiety
Myocardial Ischemia
Multi Organ Failure
Demands for O2 delivery to the tissue
Cardiac output & tissue O2 extraction
By: Dr. Somaya Banaei
Factors affecting
the risk of surgery
 Decrease of 20% of weight
 Disorders in visceral protein levels:
 Serum Albumin > 3 g/dl
 Serum transferrin > 150 mg/dl
Weakening or altering in patient system
Mortality of rate in CA
or intestinal diseases
SSI x3
I. Nutritional status assessment
By: Dr. Somaya Banaei
Factors affecting
the risk of surgery
Malnutrition!!!
Tests:
 Complete lymphocytes count
 Cell mediated immune assessment
 Neutrophil chemotaxis
 Specific lymphocyte populations count
Weakening or altering in patient system
II. Assess the adequacy of the immune system
By: Dr. Somaya Banaei
Factors affecting
the risk of surgery Weakening or altering in patient system
Old age
Malnutritio
n
CancerBurn
Severe trauma
High risk patients
II. Assess the adequacy of the immune system
By: Dr. Somaya Banaei
Factors affecting
the risk of surgery Weakening or altering in patient system
III. Other Risk factors for SSI
By: Dr. Somaya Banaei
After operation:
 Hypoxia
 Atelectasis
 Pneumonia
Most important factors in history:
 Cough
 Exacerbation
 wheezing
Pulmonary dysfunction
Factors affecting
the risk of surgery
By: Dr. Somaya Banaei
Pulmonary dysfunction
Factors affecting
the risk of surgery
O2 overuses Acidosis
By: Dr. Somaya Banaei
Delay in wound healing
Factors affecting
the risk of surgery
Smoking
Protein
deficiency
Vit C
deficiency
DehydrationSever Edema
Sever anemia
Diabetes
mellitus
By: Dr. Somaya Banaei
Delay in wound healing
Factors affecting
the risk of surgery
Hypovolemia Vasoconstriction
Increase of
blood viscosity
Intra luminal
platelets
congestion
Red blood cells
stasis
Insufficiency of
tissue oxygen
pressure
Delay in wound
healing
By: Dr. Somaya Banaei
Delay in wound healing
Factors affecting
the risk of surgery
Long period of diuretics intake
Underlying myocardial disease
High dose corticosteroids
Chemotherapy
Radiation
By: Dr. Somaya Banaei
Drugs effects  Penicillin & other antibiotics
 Opioids/ Barbiturates
 Procaine or other ansth. Drugs
 Aspirin or other analgesics
 Sulfonamides
 Tetanus Anti toxin or other serums
 Each other drugs / food (egg , milk,
chocolate)
 Iodine / Adhesive plaster
By: Dr. Somaya Banaei
Aspirin
(Acetyl salicylic acid)
I. Primary prevention
II. Secondary prevention
in patients with CVD, the lifelong use of aspirin
for secondary prevention is recommended.
Discontinuation of antiplatelet therapy may
trigger a
prothrombotic rebound phenomenon .
By: Dr. Somaya Banaei
Aspirin
(Acetyl salicylic acid)
Stop aspirin therapy for secondary CVD prevention
=
increase the risk of MI > 60%
If antiplatelet therapy is discontinued soon after PCI
The risk of stent thrombosis and MI is markedly
increased
By: Dr. Somaya Banaei
By: Dr. Somaya Banaei
If the perioperative risk of hemorrhage clearly exceeds the potential cardiovascular benefits,
aspirin therapy should be stopped.
In patients with previous PCI and stent implantation, long-term aspirin therapy should be
continued preoperatively, if possible.
However, a high risk of hemorrhage in a closed space (intracranial, intramedullary or posterior
chamber of the eye) is regarded as an important exception.
In patients treated with dual antiplatelet therapy after recent PCI, elective surgical procedures
should be postponed.
It has been recommended in guidelines to stop aspirin therapy, if indicated, 7 to 10 days before
surgery.
However, studies involving preoperative platelet function tests reported faster recovery of
platelet function
It is an expert opinion of some authors to stop aspirin, if indicated, 5 days before surgery
The European And US Guidelines
Risks for Thrombo
emboli
 Cancer
 Obesity
 Pulmonary dysfunction
 Age > 45
 History of thrombosis
By: Dr. Somaya Banaei
Old age patients
 Physiological age
 Atherosclerosis
 myocardia dysfunction > 60 y
 Silent cancer
 Low dose narcotics & anesthetics drugs
By: Dr. Somaya Banaei
The typical high risk patient is the elderly patient with
coexisting conditions such as:
 IHD
 COPD
 Undergoing major surgery
Classification of
Risk
The risk would increase if the surgery is performed as an
EMERGENCY
By: Dr. Somaya Banaei
Classification of
Risk
By: Dr. Somaya Banaei
spinal anesthesia IS NOT safer than general anesthesia for high-risk
patients.
No difference in cardiopulmonary complications or mortality.
Identification of the high risk patient
By: Dr. Somaya Banaei
I. ASA American Society of Anesthesia
II. MET Metabolic Equivalent of Task
III. RCRI Revised Cardiac Risk Index
IV. CPET Cardio Pulmonary Exercise Testing
V. POSSUM Physiologic and Operative severity Score for the enUmeration of
Morality and Morbidity
Risk scoring systems
By: Dr. Somaya Banaei
American Society of Anesthesiologists (ASA)
classification system.
By: Dr. Somaya Banaei
Revised Cardiac Risk Index for Pre-Operative Risk
(Dr. Lee Goldman)
• High-risk surgery +1
• History of ischemic heart disease + 1
• History of congestive heart failure +1
History of cerebrovascular disease +1
• Pre-operative treatment with insulin +1
• Pre-operative creatinine >2 mg/dL / 176.8 µmol/L +1
Points Class Risk
0 I 0.4 %
1 II 0.9 %
2 III 6.6 %
3 or more IV 11 %
By: Dr. Somaya Banaei
By: Dr. Somaya Banaei
1 MET
3.5 ml
O2/kg per
minute
Eating and
dressing
4 MET
Climbing
two fight
od stairs
6 MET
Short run
>10
MET
Able to
participate
in strenuous
sport
Metabolic Equivalent of Task
Patients who can exercise at 4METs or above have lower risk of
preoperative mortality
Optimizing medical management of coexisting
disease and intraoperative considerations
 Stop smoking
 Reduce alcohol intake
 Losing weight
 Improving nutrition level
 Improving Hg level
In some cases there will be a need for more complex investigations
By: Dr. Somaya Banaei
Ischemic heart disease
Preoperative MI is associated with a
High mortality (15 – 25 %)
 Supply of O2 us exceeded by its demand
 Hypotension
 Tachycardia
 Procoagulant states (SIRS)
By: Dr. Somaya Banaei
Minimizing myocardial ischemia
 Anesthesia should avoid tachycardia, systolic hypertension / diastolic hypotension
 Pain control is important
 Invasive Atrial BP monitoring
 Monitoring of blood loss and Hg level
 Oxygen supplementation is advised for 3-4 days post operatively
 Perioperative beta blocker should be considered
 Elective post operative critical care admission should be considered
By: Dr. Somaya Banaei
Cardiac Failure
 IHD
 Hypertension
 Cardiomyopathies
 Valves dysfunction
Left ventricular failure
Multi Organ Failure
By: Dr. Somaya Banaei
Cardiac Failure
 IHD
 Hypertension
 Cardiomyopathies
 Valves dysfunction
EF < 35 %
Undiagnostic failure
Its Severity underestimated
HIGHEST RISK
By: Dr. Somaya Banaei
Minimizing risks in Cardiac Failure
 The patient’s functional capacity needs to be assessed
 Surgery May Have to be delayed for investigation
 ECHO / Medication (Beta blockers / ACE inhibitors)
 Anesthesia with minimum myocardial depression
 Control Arrhythmia rapidly
 Correct electrolyte imbalance
 Invasive BP monitoring with large fluid replacement
By: Dr. Somaya Banaei
Type of Procedure
Cardiac risk for non cardiac surgery
(American College of Cardiology and the American Heart Association(
By: Dr. Somaya Banaei
 Emergent major operations, particularly in elderly
 Aortic and major Vascular procedures
 Peripheral Vascular procedures
 Prolonged procedures with large fluid shifts +/- blood loss
High 5%<
Type of Procedure
Cardiac risk for non cardiac surgery
(American College of Cardiology and the American Heart Association(
 Intraperitoneal /Intrathoracic surgery
 Carotid endarterectomy
 Head and neck surgery
 Orthopedic surgery
 Prostate surgery
By: Dr. Somaya Banaei
Intermediate 5%>
Type of Procedure
Cardiac risk for non cardiac surgery
(American College of Cardiology and the American Heart Association(
 Endoscopic procedures
 Superficial procedures
 Cataract surgery
 Breast surgery
By: Dr. Somaya Banaei
Low 1%>
Hypertension
Preoperative blood pressure
should not exceed 160/90 mmHg
Newly diagnose HTN may need further evaluation
Acute admission require urgent surgery, BP should be controlled
MORE RAPIDLY
By: Dr. Somaya Banaei
Respiratory system
 Reduce the functional residual capacity of lungs
 Respiratory depressant effects of residual anesthetic agent
 The patient’s limited mobility
 The pain from surgery causes atelectasis
 Post operative Resp. infections
 Bronchospasm
 Pneumothorax
 ARDS By: Dr. Somaya Banaei
Optimizing preoperative respiratory function
 Needs testing to assess pul. Functional status
 Consider bronchodilator +/- steroid therapy
 Arrange pre/post operative chest physiotherapy / postural drainage
 Deep breathing exercises / cough technique
 Consider regional anesthesia
 Give good quality pain relief
 Use non invasive ventilation strategies
 Avoid extubation until analgesia, hydration, acid base status have been corrected
By: Dr. Somaya Banaei
Diabetes
 Longer lengths of hospital stay,
 Increased rates of postoperative death and complications,
 Relatively greater utilization of health care resources
elevated postoperative blood glucose levels in diabetic patients
translate to progressively greater chances of SSIs
Current recommendations for desirable glucose ranges in critically
ill patients are commonly about 120-180 mg/dL
By: Dr. Somaya Banaei
Instructions for preoperative management of oral anti hyperglycemic medications.
Medication Prior to Procedure After Procedure
Short-acting sulfonylureas:
Glipizide (Glucotrol), glyburide
(DiaBeta, Glynase, Micronase)
Do not take the morning
of procedure
Resume when eating
Long-acting sulfonylureas:
ƒ Glimepiride (Amaryl), glipizide
XL (Glucotrol XL)
Do not take the
evening prior to or the morning of
procedure
Resume when eating
Biguanides: ƒ Metformin (Glucophage),
metformin ER(Glucophage XL)
Do not take the morning
of procedure; do not take the day
prior to procedure if receiving
contrast
dye
Resume when eating.
After contrast
dye wait 48 h and
repeat creatinine
prior to restarting
Thiazolidinediones:
ƒ Pioglitazone (Actos), rosiglitazone
(Avandia)
Do not take the morning
of procedure
Resume when eating
DPP-4 Inhibitors: ƒ Sitagliptin (Januvia
Do not take the morning
of procedure
Resume when eating
Meglitinides: ƒ Nateglinide
(Starlix), repaglinide(Prandin)
Do not take the morning
of procedure
Resume when eating
Alpha-glucosidase
inhibitors:Acarbose (Precose), miglitol
(Glyset)
Do not take the morning
of procedure
Resume when eating
Instructions for preoperative management of insulin.
Medication Prior to Procedure After Procedure
Glargine (Lantus)
Take usual dose the night
before or the
morning of procedure
Resume usual schedule
after procedure
Detemir (Levemir)
Take usual dose the night
before or the
morning of procedure
Resume usual schedule
after procedure
NPH (Humulin N,Novolin N)
Take ½ of usual dose the
morning of
procedure
Resume usual schedule
when eating, ½ dose while NPO
Humalog mix 70/30, 75/25, Humulin
70/30, 50/50
Novolin 70/30 (all mixed insulins)
Do not take the morning of
procedure
Resume usual schedule
when eating
Regular insulin (Humulin R, Novolin R)
Do not take the morning
of procedure
Resume when eating
Lispro (Humalog), Aspart (Novolog),
Glulisine (Apidra)
Do not take the morning of
procedure
Resume when eating
Subcutaneous insulin infusion pumps
Requires tailored recommendations. In general,
most patients may continue their usual basal
rate and correction doses, and resume mealtime
boluses when eating again
SSIs
It can reduce by multiple complex interventions that are institution-specific.
It could be result of:
 Wound contamination
 Blood loss
 Duration of the operation
 Local tissue trauma and ischemia
 Excessive electrocoagulation
By: Dr. Somaya Banaei
EXAMPLES OF PROPHYLACTIC ANTIBIOTIC SELECTIONS FOR VARIOUS OPERATIONS
Operation Standard Selection Penicillin Allergy
Distal pancreatectomy Cefazolin Vancomycin
Hernia Cefazolin Vancomycin
Thoracotomy or laparotomy Cefazolin Vancomycin
Splenectomy Cefazolin Vancomycin
Biliary (elective) Cefazolin Clindamycin gentamicin
Biliary (emergency) Ceftriaxone Clindamycin
Colorectal surgery (elective) Cefazolin/metronidazole Clindamycin gentamicin
Gastroduodenal resection Cefazolin Clindamycin gentamicin
Whipple resection Cefazolin/metronidazole Clindamycin gentamicin
Gastrointestinal (emergency) Ceftriaxone/metronidazole
Clindamycin gentamicin
Other comorbidities
 Acute Renal Failure
 Chronic renal disease
 Peripheral vascular disease
 Liver dysfunction (Child-Pugh score )
By: Dr. Somaya Banaei
Creatinine > 2mg/dl
=
By: Dr. Somaya Banaei
Child-Pugh score for Liver cirrhosis and mortality
Consultation
If it is in the best interest of the patient
If requested by the patient or the patient's family
When it is of forensic importance
If there is no consensus on how to treat the patient
If the risk of surgery is very high
If there are high-risk complications
If the patient or patient’s family is too concerned about how to treat
If there is history of specific internal or surgical diseases.
By: Dr. Somaya Banaei
ASA fasting guideline
Ingested material Minimal fasting period
Clear liquid 2h
Breast milk 4h
Infant formula 6h
Non human milk 6h
Light meal 6h
Fried foods / fatty foods or meat Additional fasting time (8 or more hours)
By: Dr. Somaya Banaei
Risk assessment and consent
All life- or limb-threatening complications
All complications with an incidence of >= 1%
 Risks: related to comorbidities, anesthesia, and surgery
 Explain: advantages, side effects, prognosis
 Language: simple, use daily life comparisons to explain risks
By: Dr. Somaya Banaei
Risk assessment and consent
All life- or limb-threatening complications
All complications with an incidence of >= 1%
 Risks: related to comorbidities, anesthesia, and surgery
 Explain: advantages, side effects, prognosis
 Language: simple, use daily life comparisons to explain risks
By: Dr. Somaya Banaei
Preoperative note
o PRE-OP DIAGNOSIS:
o PROCEDURE: planned surgery + type of Incision
o LABS: CBC, chemistries, PT/PTT, urinalysis, etc.
o CHEST X-RAY: note findings.
o ECG: note findings.
o BLOOD: not needed, type/screen or type/cross 2 units packed RBCs, etc.
o ORDERS: NPO, preoperative antibiotics, skin or colon preps, NGT, Folly
o CONSENT: signed.
By: Dr. Somaya Banaei
References:
 Current
Diagnosis And Treatment Surgery
 Baily & Love’s
Short Practice Of Surgery

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Pre operative care - Dr. Somaya Banaei

  • 1. Under Observation: Specialist Dr. Ghulam Reza Riaz Submitted By: Dr. Somaya Banaei General surgery resident Afghanistan-Herat Regional Hospital Juan. 2021
  • 2. Perioperative Care Preoperative phase – begins when the decision to have surgery is made and ends when the client is transferred to the OR table. Intraoperative phase – begins when the client is transferred to the OR table and ends when the client is admitted to the PACU. Postoperative phase - begins with the admission of the client to the PACU and ends when the healing is complete. By: Dr. Somaya Banaei
  • 3. Perioperative Care Preoperative phase – begins when the decision to have surgery is made and ends when the client is transferred to the OR table. Intraoperative phase – begins when the client is transferred to the OR table and ends when the client is admitted to the PACU. Postoperative phase - begins with the admission of the client to the PACU and ends when the healing is complete. By: Dr. Somaya Banaei DIAGNOSIS- PREOPERATIVE EVALUATION - PREPARATION
  • 4. Perioperative Care Preoperative phase – begins when the decision to have surgery is made and ends when the client is transferred to the OR table. Intraoperative phase – begins when the client is transferred to the OR table and ends when the client is admitted to the PACU. Postoperative phase - begins with the admission of the client to the PACU and ends when the healing is complete. By: Dr. Somaya Banaei ANESTHESIA - OPERATION
  • 5. Perioperative Care Preoperative phase – begins when the decision to have surgery is made and ends when the client is transferred to the OR table. Intraoperative phase – begins when the client is transferred to the OR table and ends when the client is admitted to the PACU. Postoperative phase - begins with the admission of the client to the PACU and ends when the healing is complete. By: Dr. Somaya Banaei POST ANESTHESIA CARE – ICU – INTERMEDIATE CARE- CONVALESCENCE PERIOD
  • 6. DEFINITION  The preoperative period runs from the time the patient is admitted to the hospital or surgicenter to the time that the surgery begins.  Preoperative begins with the decision to perform surgery and continues until the client has reached the operating area. By: Dr. Somaya Banaei
  • 7. INTRODUCTION The preoperative management of any patient is part of a continuum of care that extends from: THE SURGEON’S INITIAL CONSULTATION through THE PATIENT’S FULL RECOVERY. It depends on: Cause & severity of recent problem By: Dr. Somaya Banaei
  • 8. The surgeon is responsible for Balancing The Hazards of the natural history of the condition if left untreated versus the risks of an operation.  Not to screen broadly for undiagnosed disease  Identify and quantify any comorbidity that may affect the operative outcome The aim of preoperative evaluation By: Dr. Somaya Banaei
  • 9. Steps to preoperative Evaluation  History and physical examination.  Surgical Risk Factors  Preoperative Testing  Perioperative Management of medications By: Dr. Somaya Banaei
  • 10. Principles of History taking  Listen: What is the problem? (Open questions)  Clarify: What does the patient expect? (Closed questions)  Narrow: Differential diagnosis (Focused questions)  Fitness: Comorbidities (Fixed questions) By: Dr. Somaya Banaei
  • 13. Cardiovascular IHD, HTN, heartfailure, dysrhythmias,PVD, DVT,anemia Respiratory COPD, asthma,fibrotic lung, conditions, respiratory infection, malignancy Gastrointestinal PUD, bowel habits, malignancy, liver disease GenitoUrinary tract UTI, renal dysfunction Past medical History
  • 14. Neurological Epilepsy, CVA, psychiatric disorder, cognitive function Endocrine / metabolic Diabetes, thyroid dysfunction, phaeochromocytoma Locomotor system Osteoarthritis, inflammatory arthropathy Infectious Tuberculosis, hepatitis, HIV Past medical History
  • 15. Physical examination  Nervous system  Peripheral pulses  Ischemic history(claudication, diabetes)  Rectal and Pelvic exam  Pop smear (>30 years) By: Dr. Somaya Banaei
  • 16. Laboratory Exams By: Dr. Somaya Banaei  Check CBC  Serum electrolytes  Chest x-ray  ECG  Antibiogram in open wounds ( >40 years old) ( >50 years old)
  • 17. Preoperative evaluation and general condition  Peripheral perfusion  Neck vein in rest  Orthostatic changes in BP & PR  Hemoglobin for satisfied perfusion  Function of Liver / kidney  Mental status  History of bleeding  Drug history  Allergy or drugs reaction By: Dr. Somaya Banaei
  • 18. Blood transfusion preparation Autologous transfusion Blood store Hemodilution Phlebotomy By: Dr. Somaya Banaei
  • 19. Operative mortality  Is expressed in terms of deaths occurring during surgery  And up to 28 – 30 days after surgery  70% of all elective procedure have a mortality risk <1%  The high risk group has a mortality risk in EXCESS OF 5%  When the risk exceeds 20% patients are said to be extremely high risk  High risk patients - 12.5% of all surgical procedures  > 80% of deaths By: Dr. Somaya Banaei
  • 20. 0 0.5 1 1.5 2 2.5 3 3.5 4 4.5 5 Overal Standard High Risk Population size (milione) Postoperative mortality (%) Size and mortality rates for different population of surgical patients By: Dr. Somaya Banaei
  • 21. Causes After surgery  Tissue destruction  Blood loss  Fluid shifts  Change in temperature  Pain and anxiety Myocardial Ischemia Multi Organ Failure Demands for O2 delivery to the tissue Cardiac output & tissue O2 extraction By: Dr. Somaya Banaei
  • 22. Factors affecting the risk of surgery  Decrease of 20% of weight  Disorders in visceral protein levels:  Serum Albumin > 3 g/dl  Serum transferrin > 150 mg/dl Weakening or altering in patient system Mortality of rate in CA or intestinal diseases SSI x3 I. Nutritional status assessment By: Dr. Somaya Banaei
  • 23. Factors affecting the risk of surgery Malnutrition!!! Tests:  Complete lymphocytes count  Cell mediated immune assessment  Neutrophil chemotaxis  Specific lymphocyte populations count Weakening or altering in patient system II. Assess the adequacy of the immune system By: Dr. Somaya Banaei
  • 24. Factors affecting the risk of surgery Weakening or altering in patient system Old age Malnutritio n CancerBurn Severe trauma High risk patients II. Assess the adequacy of the immune system By: Dr. Somaya Banaei
  • 25. Factors affecting the risk of surgery Weakening or altering in patient system III. Other Risk factors for SSI By: Dr. Somaya Banaei
  • 26. After operation:  Hypoxia  Atelectasis  Pneumonia Most important factors in history:  Cough  Exacerbation  wheezing Pulmonary dysfunction Factors affecting the risk of surgery By: Dr. Somaya Banaei
  • 27. Pulmonary dysfunction Factors affecting the risk of surgery O2 overuses Acidosis By: Dr. Somaya Banaei
  • 28. Delay in wound healing Factors affecting the risk of surgery Smoking Protein deficiency Vit C deficiency DehydrationSever Edema Sever anemia Diabetes mellitus By: Dr. Somaya Banaei
  • 29. Delay in wound healing Factors affecting the risk of surgery Hypovolemia Vasoconstriction Increase of blood viscosity Intra luminal platelets congestion Red blood cells stasis Insufficiency of tissue oxygen pressure Delay in wound healing By: Dr. Somaya Banaei
  • 30. Delay in wound healing Factors affecting the risk of surgery Long period of diuretics intake Underlying myocardial disease High dose corticosteroids Chemotherapy Radiation By: Dr. Somaya Banaei
  • 31. Drugs effects  Penicillin & other antibiotics  Opioids/ Barbiturates  Procaine or other ansth. Drugs  Aspirin or other analgesics  Sulfonamides  Tetanus Anti toxin or other serums  Each other drugs / food (egg , milk, chocolate)  Iodine / Adhesive plaster By: Dr. Somaya Banaei
  • 32. Aspirin (Acetyl salicylic acid) I. Primary prevention II. Secondary prevention in patients with CVD, the lifelong use of aspirin for secondary prevention is recommended. Discontinuation of antiplatelet therapy may trigger a prothrombotic rebound phenomenon . By: Dr. Somaya Banaei
  • 33. Aspirin (Acetyl salicylic acid) Stop aspirin therapy for secondary CVD prevention = increase the risk of MI > 60% If antiplatelet therapy is discontinued soon after PCI The risk of stent thrombosis and MI is markedly increased By: Dr. Somaya Banaei
  • 34. By: Dr. Somaya Banaei If the perioperative risk of hemorrhage clearly exceeds the potential cardiovascular benefits, aspirin therapy should be stopped. In patients with previous PCI and stent implantation, long-term aspirin therapy should be continued preoperatively, if possible. However, a high risk of hemorrhage in a closed space (intracranial, intramedullary or posterior chamber of the eye) is regarded as an important exception. In patients treated with dual antiplatelet therapy after recent PCI, elective surgical procedures should be postponed. It has been recommended in guidelines to stop aspirin therapy, if indicated, 7 to 10 days before surgery. However, studies involving preoperative platelet function tests reported faster recovery of platelet function It is an expert opinion of some authors to stop aspirin, if indicated, 5 days before surgery The European And US Guidelines
  • 35. Risks for Thrombo emboli  Cancer  Obesity  Pulmonary dysfunction  Age > 45  History of thrombosis By: Dr. Somaya Banaei
  • 36. Old age patients  Physiological age  Atherosclerosis  myocardia dysfunction > 60 y  Silent cancer  Low dose narcotics & anesthetics drugs By: Dr. Somaya Banaei
  • 37. The typical high risk patient is the elderly patient with coexisting conditions such as:  IHD  COPD  Undergoing major surgery Classification of Risk The risk would increase if the surgery is performed as an EMERGENCY By: Dr. Somaya Banaei
  • 39. spinal anesthesia IS NOT safer than general anesthesia for high-risk patients. No difference in cardiopulmonary complications or mortality. Identification of the high risk patient By: Dr. Somaya Banaei
  • 40. I. ASA American Society of Anesthesia II. MET Metabolic Equivalent of Task III. RCRI Revised Cardiac Risk Index IV. CPET Cardio Pulmonary Exercise Testing V. POSSUM Physiologic and Operative severity Score for the enUmeration of Morality and Morbidity Risk scoring systems By: Dr. Somaya Banaei
  • 41. American Society of Anesthesiologists (ASA) classification system. By: Dr. Somaya Banaei
  • 42. Revised Cardiac Risk Index for Pre-Operative Risk (Dr. Lee Goldman) • High-risk surgery +1 • History of ischemic heart disease + 1 • History of congestive heart failure +1 History of cerebrovascular disease +1 • Pre-operative treatment with insulin +1 • Pre-operative creatinine >2 mg/dL / 176.8 µmol/L +1 Points Class Risk 0 I 0.4 % 1 II 0.9 % 2 III 6.6 % 3 or more IV 11 % By: Dr. Somaya Banaei
  • 43. By: Dr. Somaya Banaei 1 MET 3.5 ml O2/kg per minute Eating and dressing 4 MET Climbing two fight od stairs 6 MET Short run >10 MET Able to participate in strenuous sport Metabolic Equivalent of Task Patients who can exercise at 4METs or above have lower risk of preoperative mortality
  • 44. Optimizing medical management of coexisting disease and intraoperative considerations  Stop smoking  Reduce alcohol intake  Losing weight  Improving nutrition level  Improving Hg level In some cases there will be a need for more complex investigations By: Dr. Somaya Banaei
  • 45. Ischemic heart disease Preoperative MI is associated with a High mortality (15 – 25 %)  Supply of O2 us exceeded by its demand  Hypotension  Tachycardia  Procoagulant states (SIRS) By: Dr. Somaya Banaei
  • 46. Minimizing myocardial ischemia  Anesthesia should avoid tachycardia, systolic hypertension / diastolic hypotension  Pain control is important  Invasive Atrial BP monitoring  Monitoring of blood loss and Hg level  Oxygen supplementation is advised for 3-4 days post operatively  Perioperative beta blocker should be considered  Elective post operative critical care admission should be considered By: Dr. Somaya Banaei
  • 47. Cardiac Failure  IHD  Hypertension  Cardiomyopathies  Valves dysfunction Left ventricular failure Multi Organ Failure By: Dr. Somaya Banaei
  • 48. Cardiac Failure  IHD  Hypertension  Cardiomyopathies  Valves dysfunction EF < 35 % Undiagnostic failure Its Severity underestimated HIGHEST RISK By: Dr. Somaya Banaei
  • 49. Minimizing risks in Cardiac Failure  The patient’s functional capacity needs to be assessed  Surgery May Have to be delayed for investigation  ECHO / Medication (Beta blockers / ACE inhibitors)  Anesthesia with minimum myocardial depression  Control Arrhythmia rapidly  Correct electrolyte imbalance  Invasive BP monitoring with large fluid replacement By: Dr. Somaya Banaei
  • 50. Type of Procedure Cardiac risk for non cardiac surgery (American College of Cardiology and the American Heart Association( By: Dr. Somaya Banaei  Emergent major operations, particularly in elderly  Aortic and major Vascular procedures  Peripheral Vascular procedures  Prolonged procedures with large fluid shifts +/- blood loss High 5%<
  • 51. Type of Procedure Cardiac risk for non cardiac surgery (American College of Cardiology and the American Heart Association(  Intraperitoneal /Intrathoracic surgery  Carotid endarterectomy  Head and neck surgery  Orthopedic surgery  Prostate surgery By: Dr. Somaya Banaei Intermediate 5%>
  • 52. Type of Procedure Cardiac risk for non cardiac surgery (American College of Cardiology and the American Heart Association(  Endoscopic procedures  Superficial procedures  Cataract surgery  Breast surgery By: Dr. Somaya Banaei Low 1%>
  • 53. Hypertension Preoperative blood pressure should not exceed 160/90 mmHg Newly diagnose HTN may need further evaluation Acute admission require urgent surgery, BP should be controlled MORE RAPIDLY By: Dr. Somaya Banaei
  • 54. Respiratory system  Reduce the functional residual capacity of lungs  Respiratory depressant effects of residual anesthetic agent  The patient’s limited mobility  The pain from surgery causes atelectasis  Post operative Resp. infections  Bronchospasm  Pneumothorax  ARDS By: Dr. Somaya Banaei
  • 55. Optimizing preoperative respiratory function  Needs testing to assess pul. Functional status  Consider bronchodilator +/- steroid therapy  Arrange pre/post operative chest physiotherapy / postural drainage  Deep breathing exercises / cough technique  Consider regional anesthesia  Give good quality pain relief  Use non invasive ventilation strategies  Avoid extubation until analgesia, hydration, acid base status have been corrected By: Dr. Somaya Banaei
  • 56. Diabetes  Longer lengths of hospital stay,  Increased rates of postoperative death and complications,  Relatively greater utilization of health care resources elevated postoperative blood glucose levels in diabetic patients translate to progressively greater chances of SSIs Current recommendations for desirable glucose ranges in critically ill patients are commonly about 120-180 mg/dL By: Dr. Somaya Banaei
  • 57. Instructions for preoperative management of oral anti hyperglycemic medications. Medication Prior to Procedure After Procedure Short-acting sulfonylureas: Glipizide (Glucotrol), glyburide (DiaBeta, Glynase, Micronase) Do not take the morning of procedure Resume when eating Long-acting sulfonylureas: ƒ Glimepiride (Amaryl), glipizide XL (Glucotrol XL) Do not take the evening prior to or the morning of procedure Resume when eating Biguanides: ƒ Metformin (Glucophage), metformin ER(Glucophage XL) Do not take the morning of procedure; do not take the day prior to procedure if receiving contrast dye Resume when eating. After contrast dye wait 48 h and repeat creatinine prior to restarting Thiazolidinediones: ƒ Pioglitazone (Actos), rosiglitazone (Avandia) Do not take the morning of procedure Resume when eating DPP-4 Inhibitors: ƒ Sitagliptin (Januvia Do not take the morning of procedure Resume when eating Meglitinides: ƒ Nateglinide (Starlix), repaglinide(Prandin) Do not take the morning of procedure Resume when eating Alpha-glucosidase inhibitors:Acarbose (Precose), miglitol (Glyset) Do not take the morning of procedure Resume when eating
  • 58. Instructions for preoperative management of insulin. Medication Prior to Procedure After Procedure Glargine (Lantus) Take usual dose the night before or the morning of procedure Resume usual schedule after procedure Detemir (Levemir) Take usual dose the night before or the morning of procedure Resume usual schedule after procedure NPH (Humulin N,Novolin N) Take ½ of usual dose the morning of procedure Resume usual schedule when eating, ½ dose while NPO Humalog mix 70/30, 75/25, Humulin 70/30, 50/50 Novolin 70/30 (all mixed insulins) Do not take the morning of procedure Resume usual schedule when eating Regular insulin (Humulin R, Novolin R) Do not take the morning of procedure Resume when eating Lispro (Humalog), Aspart (Novolog), Glulisine (Apidra) Do not take the morning of procedure Resume when eating Subcutaneous insulin infusion pumps Requires tailored recommendations. In general, most patients may continue their usual basal rate and correction doses, and resume mealtime boluses when eating again
  • 59. SSIs It can reduce by multiple complex interventions that are institution-specific. It could be result of:  Wound contamination  Blood loss  Duration of the operation  Local tissue trauma and ischemia  Excessive electrocoagulation By: Dr. Somaya Banaei
  • 60. EXAMPLES OF PROPHYLACTIC ANTIBIOTIC SELECTIONS FOR VARIOUS OPERATIONS Operation Standard Selection Penicillin Allergy Distal pancreatectomy Cefazolin Vancomycin Hernia Cefazolin Vancomycin Thoracotomy or laparotomy Cefazolin Vancomycin Splenectomy Cefazolin Vancomycin Biliary (elective) Cefazolin Clindamycin gentamicin Biliary (emergency) Ceftriaxone Clindamycin Colorectal surgery (elective) Cefazolin/metronidazole Clindamycin gentamicin Gastroduodenal resection Cefazolin Clindamycin gentamicin Whipple resection Cefazolin/metronidazole Clindamycin gentamicin Gastrointestinal (emergency) Ceftriaxone/metronidazole Clindamycin gentamicin
  • 61. Other comorbidities  Acute Renal Failure  Chronic renal disease  Peripheral vascular disease  Liver dysfunction (Child-Pugh score ) By: Dr. Somaya Banaei Creatinine > 2mg/dl =
  • 62. By: Dr. Somaya Banaei Child-Pugh score for Liver cirrhosis and mortality
  • 63. Consultation If it is in the best interest of the patient If requested by the patient or the patient's family When it is of forensic importance If there is no consensus on how to treat the patient If the risk of surgery is very high If there are high-risk complications If the patient or patient’s family is too concerned about how to treat If there is history of specific internal or surgical diseases. By: Dr. Somaya Banaei
  • 64. ASA fasting guideline Ingested material Minimal fasting period Clear liquid 2h Breast milk 4h Infant formula 6h Non human milk 6h Light meal 6h Fried foods / fatty foods or meat Additional fasting time (8 or more hours) By: Dr. Somaya Banaei
  • 65. Risk assessment and consent All life- or limb-threatening complications All complications with an incidence of >= 1%  Risks: related to comorbidities, anesthesia, and surgery  Explain: advantages, side effects, prognosis  Language: simple, use daily life comparisons to explain risks By: Dr. Somaya Banaei
  • 66. Risk assessment and consent All life- or limb-threatening complications All complications with an incidence of >= 1%  Risks: related to comorbidities, anesthesia, and surgery  Explain: advantages, side effects, prognosis  Language: simple, use daily life comparisons to explain risks By: Dr. Somaya Banaei
  • 67. Preoperative note o PRE-OP DIAGNOSIS: o PROCEDURE: planned surgery + type of Incision o LABS: CBC, chemistries, PT/PTT, urinalysis, etc. o CHEST X-RAY: note findings. o ECG: note findings. o BLOOD: not needed, type/screen or type/cross 2 units packed RBCs, etc. o ORDERS: NPO, preoperative antibiotics, skin or colon preps, NGT, Folly o CONSENT: signed. By: Dr. Somaya Banaei
  • 68. References:  Current Diagnosis And Treatment Surgery  Baily & Love’s Short Practice Of Surgery