PowerUp! is a natural muscle builder supplement that uses nitric oxide and other natural ingredients to help users gain muscle, strength, and energy. It works by increasing the body's natural production of nitric oxide, which dilates blood vessels to improve blood flow, oxygen delivery, and muscle pumps. The benefits listed include increased strength, muscle growth, workout performance, and a lean, ripped physique. Nitric oxide is highlighted as important for vasodilation, brain function, immunity, and more. Purchase options ranging from one to nine months are provided.