Sudden Infant Death Syndrome (SIDS) causes about 2,500 infant deaths yearly in the US. While the exact cause is unknown, research investigates possible genetic, physiological, and environmental factors like prolonged QT interval, lethal arrhythmias, genetic alterations, prenatal cigarette exposure, and sleep-related issues. Continued research into causes like genetic predispositions and prenatal influences may help explain SIDS and potentially prevent future deaths.