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Please show reagents necessary for reactions A-F and briefly describe type of chemistry taking
place for all reactions (A-F).
Solution
a) (i) LiAlH4 (2.0eq)/THF/H3O+, (ii) PBr3(1.0eq), NaOH (ts a intramolecular etherification
reaction)
b) (i) LiAlH4 (1.0eq)/THF/H3O+, (ii) SOCl2/DCM (its aintramolecular lactionazationation
reaction)
c) (i) LiAlH4 (2.0eq)/THF/H3O+, (Reduction)
d) (ii) SOCl2(2.0 eq)/DCM/ NH3 (2.0 eq) (amideformation reaction)
E) MeOH/H2SO4 (esterfication reaction)
f) (i) LiAlH4 (2.0eq)/THF/H3O+, (ii) PBr3(2.0eq), (iii) NaNH2 (2.0eq) (amination reaction)
g) (i) LiAlH4 (1.0eq)/THF/H3O+, (ii) PBr3(1.0eq), iii) NaNH2 (1.0 eq), (iv) SOCl2 (1.0 eq)

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Please show reagents necessary for reactions A-F and briefly describ.pdf

  • 1. Please show reagents necessary for reactions A-F and briefly describe type of chemistry taking place for all reactions (A-F). Solution a) (i) LiAlH4 (2.0eq)/THF/H3O+, (ii) PBr3(1.0eq), NaOH (ts a intramolecular etherification reaction) b) (i) LiAlH4 (1.0eq)/THF/H3O+, (ii) SOCl2/DCM (its aintramolecular lactionazationation reaction) c) (i) LiAlH4 (2.0eq)/THF/H3O+, (Reduction) d) (ii) SOCl2(2.0 eq)/DCM/ NH3 (2.0 eq) (amideformation reaction) E) MeOH/H2SO4 (esterfication reaction) f) (i) LiAlH4 (2.0eq)/THF/H3O+, (ii) PBr3(2.0eq), (iii) NaNH2 (2.0eq) (amination reaction) g) (i) LiAlH4 (1.0eq)/THF/H3O+, (ii) PBr3(1.0eq), iii) NaNH2 (1.0 eq), (iv) SOCl2 (1.0 eq)