2. P
Population/problem
214 uncomplicated PTA patients that underwent contrasted CT -scan of the
neck from 3 hospitals in a single academic health system
PICO
I Intervention
Sole Medical Theraphy (MT), SurgicalTheraphy (ST)
C
Comparison
87 patients treated with MT (intravenous antibiotics and steroids) and 127
patients treated with ST (MT plus drainage)
O
Outcome
Treatment safety between MT and ST in PTA patient based on abscess size and
predict the treatment failure.
3. Design of Study
Method of Study
Retrospective Cohort Study
Focus of Study
Treatment failure and efficacy
between MT vs ST in PTA patients
Worksheet
Efficacy and safety
4. 4
Question Answers
Are the results of this study
valid?
Yes
Was a defined, representative
sample of patients assembled
at a common?
Yes
Was patient follow-up
sufficiently complete?
Yes
Validity
5. 5
Question Answers
Are the results of this study
important?
Yes
How precise is this efficacy
and safety is estimate?
• Treatment failure occurred in 8% of the MT group and
7.9% of the ST group (P = 1.00).
• In PTAs <2 cm, treatment failure occurred in 5.3% of
the MT group and 5.0% of the ST group (P = 1.00).
• In PTAs ≥2 cm, treatment failure occurred in 13.3% of
the MT group and 9.0% treated with ST (P = 0.53).
• Size ≥2 cm (OR – 3.46, P = .08) and IV clindamycin as
sole IV antibiotic (OR – 2.46, P = 0.15) trended toward
predicting treatment failure.
• Considered failures, 7% of the ST group returned to the
ED with pain versus 0% of the MT group (P = 0.01).
Importance
6. 6
Question Answers
Is our patient same from those in
the study that its results can
apply?
Yes
Will this evidence make a clinically
important impact on our
conclusions about what to offer or
tell our patient?
Yes
Applicability
7. 7
• This appraised study is VALID
• CLINICAL IMPORTANCY was described well in the
article and result of the study was statistically
significant.
• The results and method of the trial were quite
APPLICABLE to be implemented for patients in Zainoel
Abidin General Hospital
Conclusion
