This document discusses various topics related to pharmacology including definitions of drugs, classifications of drugs, subdivisions of pharmacology, sources of drug information, essential medicines, orphan drugs, drug schedules, and drug nomenclature. It provides classifications of prescription drugs and over-the-counter drugs. It also summarizes key concepts in pharmacokinetics, pharmacodynamics, pharmacotherapeutics, and toxicology.
www.linkedin.com/in/dr-aboobecker-siddique-p-a-200783a0
General Pharmacology
Introduction to pharmacology
Definition of pharmacology and its subdivisions, Sources of drug info and category of info for each source, Sources of drugs and drug nomenclature.
Pharmaceutics
Routes, Factors determine selection of routes, advantages and disadvantages,of enteral, parenteral inhalational routes, and transdermal routes
Membrane transport mechanism, Bioavailability factors and definition, factors influencing drug distribution pattern, Biotransformation,-Definition, phases, sites, Factors affecting,
Drug elimination-Routes of excretion, factors affecting renal excretion, halflife definition and importance, dose response and steady state concentration
MO drug action, Factors that modify, drug interaction
Safety margin and drug toxicity 1h
TI, Untoward effects-predictable unpredictable and others, Principles of management of drug toxicity
definition
why study pharmacology
subdivision
clinical pharmacology
source of information of drugs
nomenclature of drugs
sources of drugs
www.linkedin.com/in/dr-aboobecker-siddique-p-a-200783a0
General Pharmacology
Introduction to pharmacology
Definition of pharmacology and its subdivisions, Sources of drug info and category of info for each source, Sources of drugs and drug nomenclature.
Pharmaceutics
Routes, Factors determine selection of routes, advantages and disadvantages,of enteral, parenteral inhalational routes, and transdermal routes
Membrane transport mechanism, Bioavailability factors and definition, factors influencing drug distribution pattern, Biotransformation,-Definition, phases, sites, Factors affecting,
Drug elimination-Routes of excretion, factors affecting renal excretion, halflife definition and importance, dose response and steady state concentration
MO drug action, Factors that modify, drug interaction
Safety margin and drug toxicity 1h
TI, Untoward effects-predictable unpredictable and others, Principles of management of drug toxicity
definition
why study pharmacology
subdivision
clinical pharmacology
source of information of drugs
nomenclature of drugs
sources of drugs
I upload a series of knowledge for pharmaceutical professional such as students and other specialized field. Presentation for "LEARN & EARN KNOWLEDGE" based.
presented by: Miss Prajakta D. sawant, Lecturer at Genesis Institute of Pharmacy, radhanagari.
SECOND YEAR DIPLOMA IN PHARMACY. PHARMACOLOGY AND
TOXICOLOGY(0813).
General Pharmacology Lecture Slides on introduction to Pharmacology by Sanjaya Mani Dixit Assistant Professor of Pharmacology at Kathmandu Medical College
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NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
I upload a series of knowledge for pharmaceutical professional such as students and other specialized field. Presentation for "LEARN & EARN KNOWLEDGE" based.
presented by: Miss Prajakta D. sawant, Lecturer at Genesis Institute of Pharmacy, radhanagari.
SECOND YEAR DIPLOMA IN PHARMACY. PHARMACOLOGY AND
TOXICOLOGY(0813).
General Pharmacology Lecture Slides on introduction to Pharmacology by Sanjaya Mani Dixit Assistant Professor of Pharmacology at Kathmandu Medical College
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
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Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
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Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
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www.agostodourado.com
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
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Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
3.
As per WHO Scientific group
“Any Substance or product that is used and intended to be
used to modify or explore the physiological system or
pathological state for the benefit of the recipient “
4.
Drug categories
Prescription drugs
Are used under only medical
supervision and dispensed by an order
of medical practitioner only
OTC drugs
Can be sold over the counter
without prescription
5.
Sub divisions of Pharmacology
Pharmacology
Pharmacokinetics
Pharmacodynamics
Pharmacotherapeutics
Clinical pharmacology
Toxicology
Deals with ADME process i.e. what the body
does to the drug
Deals with the biological effect of the drug ,its
mechanism of action and relation b/w its
plasma concentration ,its response and
duration of action i.e. What the drug does to
the body .
Clinical application of pharmacodynamics and
pharmacokinetics information to cure a disease
.
Deals with the comparative clinical evaluations of
new drug for developing its therapeutic efficacy
and safety
Deals with the toxicity and poisonous effects of
various chemicals and also with the symptoms
and treatment of poisoning
6.
Pharmacology
Chemotherapy
Pharmacogenetics
Pharmacogenomics
Pharmacoepidemeiology
Pharmacovigilance
Deals with the systemic infection or malignancy with
drugs with selective toxicity for infecting organisms.
Deals with the study of inherited (single gene
mediated)differences in the drug metabolism or drug
response in humans.
Deals with the genetic make up (Genome) of
individual to choose drug therapy .
Deals with the study of use and effects of the
drug in large population to establish risk:
Benefit ratio of the drug .
Deals with the continuous monitoring for unwanted
effects and other safety related aspects of marketed
drugs . Science related to DAUP
(Detection, Assessment. Understanding and Prevention)
7.
Sources of Information
Official
Non Official
Martindale
Drug Compendia
Pharmacopoeias
Formularies
Pharmacopoeias Formulary
British pharmacopoeias Pharmaceutical codex(by pharmaceutical
Society of Great Britain )
United states Pharmacopoeias National Formulary (by American
Pharmaceutical Association)
Indian Pharmacopoeias National Formulary of India
8.
Serves as Secondary Source of drug Information both by Generic name
and Trade name
This Information is generalized and is not restricted to only those
drugs which are approved for use by the legally constituted
committee of that country .
For Example :
1. AMA Drug Evaluation : by American Medical Association and
Council on Drugs
2. Modern Drug Encyclopedia: by Yorkee Medical books , New York,
USA
3. Physician’s Desk Reference (PDR) : by Medical Economics
Publications ,USA
4. Martindale Extra Pharmacopoeias : by Pharmaceutical Society of
Great Britain .
Non offical Compendia
9.
A drug generally has three categories of names:
(a)Chemical name
It describes the substance chemically, e.g. 1-
(Isopropylamino )-3-(1-naphthyloxy) propan-2 –ol for
propranolol.
(b) Non-proprietary / official name / Approved name
Name in the official books accepted all over the world
(c)Proprietary (Brand) name
Crocin for Paracetamol
DRUG NOMENCLATURE
11.
Essential medicines, as defined by the WHO are
"those drugs that satisfy the health care needs of the
majority of the population; they should therefore be
available at all times in adequate amounts and in
appropriate dosage forms, at a price the community
can afford."
Essential medicines
12.
These are drugs or biological products for diagnosis/treatment/
prevention of a rare disease or condition, or a more common disease
(endemic only in resource poor countries) for which there is no
reasonable expectation that the cost of developing and marketing it
will be recovered from the sales of that drug.
e.g. sodium nitrite, fomepizole, liposomal amphotericin B,,
rifabutin,, somatropin, digoxin immune Fab (digoxin
antibody), liothyronine (T3) and many more.
Governments in developed countries offer tax benefits and other
incentives to pharmaceutical companies for developing and marketing
orphan drugs (e.g. Orphan Drug Act in USA).
Orphan Drugs
13.
Includes the drugs with high potential of Abuse Eg. LSD, Heroin
.Marijuana, Flunitrazepam and Methaqualone
Includes morphine ,codiene, pethidine, fentanyl, cocaine,
amphetamine,methylphenidate, pentobarbital and secobarbital
.these can be used under medical supervision only
The drugs with moderate physical and psychological dependence
eg. Stanzolol, ketamine ,nalorphine ,thiopental ,suppository form
of secobarbital and pentobarbital etc
They have low potential for abuse and have limited physical and
pshycological dependence eg. Long acting barbiturates
,Benzodiazapines, Propoxyphene ,Pentazocine ,Premolineolpidem
and Zaleplon
They have minimal use abuse potential and minimum
dependence liability eg Lamotil and formulation containing
Codiene while others are OTC drugs.,
Laws governing Drugs (Drugs
Schedule ) AS per detailed in USP Vol.XXII and by NF
Schedule I
Schedule II
Schedule III
Schedule IV
Schedule V
14.
Schedules
A-
Prescribed
forms
B-State
fees
C and C 1-
Biological
and special
products
D-
Import
of Drugs
E 1-
Poisonous
Substances
F &
F(I)-
Standards Of
Bacterial
Vaccines
FF-
Opthalmic
preparations
F(II)-
Surgical
dressings
and bandage
cloth
F(III)-
Umbilical
tapes
G- Drugs
with Label
CAUTION
H-
Prescription
Drugs
J-List of
Ailments
K-Exemtions
from
provisions of
chapter IV of
drug act
M-
GMP
M1- Mfg of
Homeopathi
c Drugs
M-II- Mfg
of
Cosmetics
M-III- Mfg of
medical
devices
15.
Schedules
N- equipments,
entrance
,premises,furnitu
re, apparatus &
general
provisions
O-
Disinfectants
fluids
P- Expiry
period
P 1- Pack
Sizes of
drugs
Q- Dyes
,colours,
pigments used
in cosmetics
and soaps
R- Mechanical
Contraceptives
R-1- Medical
devices
S-
Standards
of
cosmetics
T-requirments
of factory
premises,
hygienic
conditions for
Ayurvedic &
Unani drugs.
U & U1- Mfg
Records
V-Patents &
Proprietary
medicine
W-Names of
drugs which
can be
marketed under
generic names
only .
X- Pshycotropic
drugs req. special
licences for mfg
and sale
Y- req. & guidelines
on clinical trials,
import & mfg of
new drugs.
16.
Bibliography
•Essentials of Medical Pharmacology -7th edition by KD Tripathi
•Goodman & Gilman's the Pharmacological Basis of Therapeutics 12th edition
by Laurence Brunton (Editor)
•Lippincott's Illustrated Reviews: Pharmacology - 6th edition by Richard A.
Harvey
•Basic and Clinical pharmacology 11th edition by Bertram G Katzung
•Rang & Dale's Pharmacology -7th edition
by Humphrey P. Rang
•Clinical Pharmacology 11th edition By Bennett and Brown, Churchill Livingstone
•Principles of Pharmacology 2nd edition by HL Sharma and KK Sharma
•Review of Pharmacology by Gobind Sparsh