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PAC OF CARDIAC PATIENTS FOR
NON-CARDIAC SURGERY,
CARDIAC RISK ASSESSMENT
Presented by:
Pooja Pandeya
1st year Resident
Department of Anesthesiology
INTRODUCTION
• Cardiovascular complications: 25-50% deaths following non-cardiac
surgeries
• Major Adverse Cardiac Event (MACE): composite term  Includes
Acute Myocardial Syndrome, stroke, cardiovascular death, coronary
revascularization and heart failure
• By 2030, 20% individuals aged >75 years will undergo surgery each
year
GUIDELINES FOR RISK ASSESSMENT
• ACC/ AHA Task force report 2014
• ESC/ESA 2022 guidelines
• CCS 2019 guidelines
DEFINITIONS
• Emergency procedure: Life or limb threatened if not in the operating room
(<6hrs)
• Urgent procedure: Limited time for clinical evaluation (6-24 hrs)
• Time sensitive procedure: 1 to 6 weeks to allow for an evaluation and
significant changes in management will negatively affect outcome
• Elective procedure: Could be delayed for up to 1 year
• Low-risk procedure: <1% risk of MACE
• Elevated risk procedure: >1% risk of MACE
AIMS OF PAC
• Identification potentially life-threatening cardiac disease
• Order appropriate tests only
• Stratifications of risks
• Implementation most appropriate medical and interventional
cardiovascular treatment strategies
HISTORY
• Chest pain
• SOB
• Easy fatigability
• Palpitations
• Orthopnea, PND
• Syncope
• Relation of symptoms with activity level
• Hemoptysis
DUKES ACTIVITY STATUS INDEX
EXAMINATION
• Pallor, edema, cyanosis, neck veins
• BP (different positions)
• Pulse
• RR
• Precordium
• Apex beat
• Heart sound and murmur
• Lung bases
• Bruits
NYHA CLASSIFICATION
GOLDMAN MULTIFACTORIAL CARDIAC RISK INDEX
REVISED CARDIAC RISK INDEX SCORING (RCRI)
CARDIAC AND SURGICAL RISK CALCULATORS
• ACS NSQIP MICA Surgical Risk Calculator
• 21 patient-specific variables for prediction of several groups of
outcomes
• https://riskcalculator.facs.org/RiskCalculator/
9/16/2023 Nams 16
DIABETES MELLITUS
• Accelerate progression of atherosclerosis  CAD
• Require Insulin  Higher risk
• Duration of disease
• End organ dysfunction
• Autonomic neuropathy  silent ischemia
HYPERTENSION
• Look for LVH, end organ damage
• JNC -8
• 180/110 mmHg  Evidence
• Optimize VS risk of delaying surgery
METABOLIC SYNDROME
• High BP + Dyslipedemia + FBS + Central obesity
• Cardiovascular + Pulmonary + Renal Complication + Wound infection
INVESTIGATIONS
• 12-lead ECG
• Tropinin I, CK-MB, LDH-1: h/o recent unstable angina
• Echocardiography
• Exercise stress test
• Pharmacological stress test
• Coronary Angiography
ECG
• Left ventricular hypertrophy
• Abnormal Q waves
• Known CAD or other structural heart disease (except for low-risk surgical
procedures)
• Asymptomatic patients with clinical risk factors (except for low-risk procedures)
ECHOCARDIOGRAPGY
• Regional wall motion abnormalities, wall thickness, valvular function,
EF
• Dyspnea of unknown origin
• Current or prior heart failure with worsening dyspnea
• Valvular stenosis or regurgitation with no echocardiography studies
within 1 year, or worsening clinical status
• Aortic stenosis  poor prognosis in noncardiac surgical patient
• Modify perioperative hemodynamic goals and therapy
EXERCISE STRESS TEST
• Sensitivity = 70% -80%
• Specificity = 60% -75% for identifying CAD
• Positive exercise stress test  risk for ischemia associated with
increased heart rate
• Greatest risk  Ischemia after mild exercise
• Ability to exercise No further testing
PHARMACOLOGICAL STRESS TEST
• High-risk patients who either are unable to exercise or have
contraindications to exercise
• Dobutamine  Regional wall motion abnormality
CORONARY ANGIOGRAPHY AND PCI
• Patients with restricted physical activity in whom functional capacity
difficult to determine
• Not recommended for elective surgeries
BETA BLOCKER
• Chronic use  continue
• RCRI >3  May consider  Not on day of surgery
STATIN THERAPY
• Continue if currently taking
• Vascular surgery  may start
• Elevated risk procedure
REFERENCES
• 2014 ACC/AHA Guideline on Perioperative Cardiovascular Evaluation
and Management of Patients Undergoing Noncardiac Surgery
• Barash PG, Cullen BF, Stoelting RK, Cahalan MK, Stock MC. Clinical
Anesthesia. 8th ed.
• Morgan GE, Mikhail MS, Murray MJ. Clinical Anesthesiology. 7th ed
• Stoelting’s Anesthesia And co existing Disease –7 th edition
• For Professionals | Heart Foundation
THANK YOU

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PAC OF CARDIAC PATIENTS FOR NON-CARDIAC SURGERY,.pptx

  • 1. PAC OF CARDIAC PATIENTS FOR NON-CARDIAC SURGERY, CARDIAC RISK ASSESSMENT Presented by: Pooja Pandeya 1st year Resident Department of Anesthesiology
  • 2. INTRODUCTION • Cardiovascular complications: 25-50% deaths following non-cardiac surgeries • Major Adverse Cardiac Event (MACE): composite term  Includes Acute Myocardial Syndrome, stroke, cardiovascular death, coronary revascularization and heart failure • By 2030, 20% individuals aged >75 years will undergo surgery each year
  • 3. GUIDELINES FOR RISK ASSESSMENT • ACC/ AHA Task force report 2014 • ESC/ESA 2022 guidelines • CCS 2019 guidelines
  • 4. DEFINITIONS • Emergency procedure: Life or limb threatened if not in the operating room (<6hrs) • Urgent procedure: Limited time for clinical evaluation (6-24 hrs) • Time sensitive procedure: 1 to 6 weeks to allow for an evaluation and significant changes in management will negatively affect outcome • Elective procedure: Could be delayed for up to 1 year • Low-risk procedure: <1% risk of MACE • Elevated risk procedure: >1% risk of MACE
  • 5. AIMS OF PAC • Identification potentially life-threatening cardiac disease • Order appropriate tests only • Stratifications of risks • Implementation most appropriate medical and interventional cardiovascular treatment strategies
  • 6. HISTORY • Chest pain • SOB • Easy fatigability • Palpitations • Orthopnea, PND • Syncope • Relation of symptoms with activity level • Hemoptysis
  • 8. EXAMINATION • Pallor, edema, cyanosis, neck veins • BP (different positions) • Pulse • RR • Precordium • Apex beat • Heart sound and murmur • Lung bases • Bruits
  • 11. REVISED CARDIAC RISK INDEX SCORING (RCRI)
  • 12. CARDIAC AND SURGICAL RISK CALCULATORS • ACS NSQIP MICA Surgical Risk Calculator • 21 patient-specific variables for prediction of several groups of outcomes • https://riskcalculator.facs.org/RiskCalculator/
  • 13.
  • 14.
  • 16. DIABETES MELLITUS • Accelerate progression of atherosclerosis  CAD • Require Insulin  Higher risk • Duration of disease • End organ dysfunction • Autonomic neuropathy  silent ischemia
  • 17. HYPERTENSION • Look for LVH, end organ damage • JNC -8 • 180/110 mmHg  Evidence • Optimize VS risk of delaying surgery
  • 18. METABOLIC SYNDROME • High BP + Dyslipedemia + FBS + Central obesity • Cardiovascular + Pulmonary + Renal Complication + Wound infection
  • 19.
  • 20. INVESTIGATIONS • 12-lead ECG • Tropinin I, CK-MB, LDH-1: h/o recent unstable angina • Echocardiography • Exercise stress test • Pharmacological stress test • Coronary Angiography
  • 21.
  • 22. ECG • Left ventricular hypertrophy • Abnormal Q waves • Known CAD or other structural heart disease (except for low-risk surgical procedures) • Asymptomatic patients with clinical risk factors (except for low-risk procedures)
  • 23. ECHOCARDIOGRAPGY • Regional wall motion abnormalities, wall thickness, valvular function, EF • Dyspnea of unknown origin • Current or prior heart failure with worsening dyspnea • Valvular stenosis or regurgitation with no echocardiography studies within 1 year, or worsening clinical status • Aortic stenosis  poor prognosis in noncardiac surgical patient • Modify perioperative hemodynamic goals and therapy
  • 24. EXERCISE STRESS TEST • Sensitivity = 70% -80% • Specificity = 60% -75% for identifying CAD • Positive exercise stress test  risk for ischemia associated with increased heart rate • Greatest risk  Ischemia after mild exercise • Ability to exercise No further testing
  • 25. PHARMACOLOGICAL STRESS TEST • High-risk patients who either are unable to exercise or have contraindications to exercise • Dobutamine  Regional wall motion abnormality
  • 26. CORONARY ANGIOGRAPHY AND PCI • Patients with restricted physical activity in whom functional capacity difficult to determine • Not recommended for elective surgeries
  • 27.
  • 28.
  • 29. BETA BLOCKER • Chronic use  continue • RCRI >3  May consider  Not on day of surgery
  • 30. STATIN THERAPY • Continue if currently taking • Vascular surgery  may start • Elevated risk procedure
  • 31.
  • 32.
  • 33. REFERENCES • 2014 ACC/AHA Guideline on Perioperative Cardiovascular Evaluation and Management of Patients Undergoing Noncardiac Surgery • Barash PG, Cullen BF, Stoelting RK, Cahalan MK, Stock MC. Clinical Anesthesia. 8th ed. • Morgan GE, Mikhail MS, Murray MJ. Clinical Anesthesiology. 7th ed • Stoelting’s Anesthesia And co existing Disease –7 th edition • For Professionals | Heart Foundation

Editor's Notes

  1. (an important aspect because non-invasive and invasive testing are not only associated with patient discomfort and financial burden, but also with morbidity and mortality related to the test procedure, false test results, and postponement of required surgery
  2. Hemoptysis in mitral stenosis  increase PAH  rupture of vessels
  3. One metabolic equivalent (MET) is defined as the amount of oxygen consumed while sitting at rest and is equal to 3.5 ml O2 per kg body weight x min 1 L O2 = 5kcal
  4. BP: White coat syndrome
  5. Medical history or conditions including the presence of PO2 less than 60; PCO2 greater than 50; K below 3; HCO3 under 20; BUN over 50; serum creatinine greater than 3; elevated SGOT; chronic liver disease; or the state of being bedridden (3 points) Class I (0 to 5 points): correlates with a 1.0% risk of cardiac complications during or around noncardiac surgery. Class II (6 to 12 points): correlates with a 7.0% risk of cardiac complications during or around noncardiac surgery. Class III (13 to 25 points): correlates with a 14% risk of cardiac complications during or around noncardiac surgery. Class IV (26 to 53 points): correlates with a 78% risk of cardiac complications during or around noncardiac surgery.
  6. High risk type surgeries: open intraperitoneal , intrathoracic, vascular surgeries Risk of death, MI or cardiac arrest Ischemic heart disease: previous MI, abnormal exercise ECG, chest pain, use of nitrates, Q waves CHF: s3 gallop rhythm, PND, pulmonary edema, crackles in chest
  7. American College of Surgeons (ACS) National Surgical Quality Improvement Program (NSQIP) Myocardial Infarction and Cardiac Arrest (MICA)
  8. ECG  Qwaves
  9. Joint National Committee
  10. TAG >200 mg/dl and LDL >100 mg/dl Abdominal circumference >90cm for male , >80 cm for female
  11. Radionucleotide ventriculography
  12. CLAUDICATION dipyridamole/adenosine/regadenoson 1498 myocardial perfusion imaging (MPI) with thallium-201 and/or technetium99m and rubidium-82. Dipyridamole, adenosine, or regadenoson is administered as a coronary vasodilator to assess flow heterogeneity and the presence of a redistribution defect.
  13. Patients with acute STEMI Non STEMI and unstable angina Angina unresponsive to medical therapy May be considered: Undergoing high risk surgery Undergoing intermediate surgery
  14. Dabigatran: Thrombin/ IIa inhibitor Fondaparinux: Activates antithrombin  neutralize Xa Rivoroxaban: Xa inhibitor Apixaban Xa inhibitor