Oxygen sensor Oct 2012
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This document describes an oxygen sensing technology developed by Dr. Nuno Faria and Prof. Jonathan Powell at the Medical Research Council in Cambridge, UK. The technology uses a cheap modification of mineral structures to create an oxygen sensor that provides an irreversible color change. Key features include a clearly visible color change, tunable color and oxygen sensitivity, low cost and safe materials, and potential incorporation into materials like packaging. The sensors are composed of metal oxide particles modified with organic ligands to control the color change triggered by oxygen exposure.
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Oxygen sensor Oct 2012
- 1. Oxygen Sensing Minerals Dr Nuno Faria and Prof Jonathan Powell Medical Research Council Cambridge UK Challenge sponsored by:
- 2. The Technology • We have developed and patented an oxygen sensor technology based on a cheap, scaleable modification of mineral structures • Our oxygen sensors can provide an irreversible colour change and can be incorporated into a variety of settings
- 3. Key Features •Clearly indicates changes - Colour change upon oxygen exposure is striking • Colour, composition, oxygen sensitivity can all be tailored to meet specific requirements - Minimum exposure time required for a colour change can be adjusted from a few minutes to several days. - Many possible colour combinations •Accurate and effective - Sensitivity can be adjusted to different oxygen levels as required per specific application • Can be incorporated within various materials during its manufacture • Low cost - Synthesis is a one-step aqueous process that uses cheap reagents commonly used in the food industry; manufacturing process is easily scalable • Safe for contact with food
- 4. The Material • The sensors are composed of metal oxide particles, which have been modified by incorporating organic molecules (ligands) during manufacture • The type of metal and ligand as well as size and crystallinity of particles can be tailored to achieve specific properties • The metal is present in its reduced state. Exposure to oxygen oxidizes the metal ions, resulting in a colour change of the particles. • Particles can be incorporated into various materials (e.g. gels, paper, plastic).
- 5. Tailorable with different ligands Ligand Mix A Ligand Mix B +O2 - O2 The incorporation of different ligands into the mineral can be used to tailor the colour shift and reactivity to oxygen.
- 6. Various mineral phases can be produced Mineral Phase I Mineral Phase II +O2 - O2 A range of mineral phases can be synthesised. These differ considerably in their composition and physicochemical properties.
- 7. Nanoparticulate sensors Before Sensors present as oxygen particles in suspension exposure - Can be produced as stable colloidal suspensions - Can spray-dried onto surfaces (e.g. packaging After materials) oxygen - As with the sensors in a solid exposure matrix (previous slides), altering the synthesis conditions (sensors A-I) A B C D E F G H I results in distinct colour shifts
- 8. Manufacturing • Low production costs - Low cost reagents used - One-step synthesis at room temperature - No solvents required • Straightforward scale-up -Preliminary syntheses have already been carried out by a manufacturing CRO • Easy incorporation into various materials (e.g. packages) - Particles can be easily spray-dried or coated onto everyday materials (paper, gels etc)
- 9. Summary • Does not need expensive sensing equipment • Colour change can be reversible or irreversible • Does not bleach upon exposure to light • Safe - Existing sensors are built from materials that should not be ingested - Our sensors are ‘assembled’ from GRAS reagents used in the food industry • Cheap - Aqueous synthesis that uses inexpensive reagents